Banca de DEFESA: RICARDO NEY OLIVEIRA COBUCCI

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE: RICARDO NEY OLIVEIRA COBUCCI
DATA: 19/12/2011
HORA: 09:00
LOCAL: Sala de Reuniões CONSEC, 2º andar do CCS - UFRN
TÍTULO:

COMPARATIVE INCIDENCE OF CANCER IN HIV- AIDS PATIENTS AND TRANSPLANT RECIPIENTS.

PALAVRAS-CHAVES:

Neoplasm, Incidence, HIV, Acquired Immunodeficiency Syndrome, Transplants

PÁGINAS: 60
GRANDE ÁREA: Ciências da Saúde
ÁREA: Medicina
RESUMO:

Abstract: Background: Studies have found a relationship between decreased immunity and increased incidence of cancer. Methods: A systematic review of observational studies evaluating the incidence of cancer in both organ recipients and people with HIV/AIDS compared with the general population. Eligible studies were searched up to March 2011 in the following databases: Pubmed, Embase, Scielo, Cancerlit and Google scholar. In this study, the Standardized incidence ratios (SIR) of cancer in people with HIV/AIDS and of organ transplant recipients were compared with those found among the general population. Results: Twenty-five studies of transplant and HIV-associated cancer risk, involving 866 776 people with HIV/AIDS or organ recipients and 21 260 new cases of cancer, were included. The risk for development of new cancer cases were higher among people with HIV/AIDS (SIR=4, IC95% 3.78-4.24)and who received organs (SIR=3.28, IC95% 3.06-3.52) when compared with the general population. Conclusion: Similar SIR in both immunocompromised populations suggests that the weakened immune system is responsible for the increased risk of new cases of cancer among these groups. Research investments are needed to develop effective cancer prevention strategies in these populations.

MEMBROS DA BANCA:
Presidente - 1199080 - ANA KATHERINE DA SILVEIRA GONCALVES
Externo ao Programa - 2149416 - MARIA DA CONCEICAO MESQUITA CORNETTA
Externo à Instituição - MARIA GORETTI FREIRE DE CARVALHO - UnP