Banca de QUALIFICAÇÃO: ERICA LIRA DA SILVA FREITAS

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
DISCENTE: ERICA LIRA DA SILVA FREITAS
DATA: 30/10/2013
HORA: 14:00
LOCAL: SALA DE AULA 01 - PPGCSA
TÍTULO:

DESENVOLVIMENTO DE SISTEMAS MAGNÉTICOS PARA VETORIZAÇÃO DE ANTIBIÓTICOS NO TRATO GASTROINTESTINAL

PALAVRAS-CHAVES:

Magnetite, Polymeric particles, Amoxicillin, Spray drier, Antimicrobial activity

PÁGINAS: 24
GRANDE ÁREA: Ciências da Saúde
ÁREA: Medicina
RESUMO:

The aim of this work is to develop and evaluate polymeric magnetic particles loaded with the amoxicillin as a potential drug delivery device. The magnetite particles were produced by the co-precipitation method. Therefore, the particles were coated with the Eudragit^® S100 and amoxicillin by the spray-drying technique. The physicochemical characterization of the particles was performed by Optical and Scanning Electron Microscopy, X-ray Powder Diffraction, Nitrogen Adsorption/Desorption Isotherms, Vibrating Sample Magnetometry and Drug Release Test. Additionally, the antibacterial activity of the particles was evaluated against Micrococcus luteus. The results suggested that the produced particles have a potential antimicrobial activity and may be considered as an effective antibiotics carrier. 

MEMBROS DA BANCA:
Externo à Instituição - ANA LUCIA DANTAS - UERN
Presidente - 345702 - ARTUR DA SILVA CARRICO
Externo ao Programa - 1674707 - MARCO ANTONIO MORALES TORRES