ACUTE EFFECT OF HIGH-INTENSITY INTERVAL EXERCISE AND MODERATE-INTENSITY CONTINUOS EXERCISE ON IMMUNOLOGICAL AND INFLAMMATORY PROFILE IN OBESE MALES
Obesity, Aerobic Exercise, High Intensity Interval Training; INF-Y/IL-4; Inflammation.
Objective: The aim of this study was to compare the acute effects of high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE) on cytokine levels, include interferon-y (INF-y), interleukin 4 and 6 (IL-4) (IL-6) levels and INF-y/IL-4 ratio in obese males. Methods: Ten obese males were submitted into two experimental sessions with a week interval in a randomized order: 1) HIIE: 10 x 60 s at 90% of HRmáx interspersed by active recovery; 2) MICE: 20 min at 70% of HRmax;. Cytokines was analyzed before, post and 60 min post-exercise. Results: The HIIE results in decrease of INF-Y levels at immediately post-exercise (P=0,032) and 60 min post-exercise (P=0,003) at the same time elevated the IL-4 levels at post-exercise (P=0,007). The MICE results in increase of INF-Y at post-exercise (P=0,025) and 60 min post-exercise (P=0,004). Both exercise conditions results in increase of IL-6 levels at post-exercise (P<0.05). Conclusion: a single session of HIIE suppressed the immune cell response, increasing the “open window” for infections to 60 min post exercise. For other hand, a single session of MICE increased the immune cell response to 60 min post exercise in obese males.