Banca de QUALIFICAÇÃO: THATYANE OLIVEIRA SOUZA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : THATYANE OLIVEIRA SOUZA
DATE: 22/11/2019
TIME: 09:00
LOCAL: Sala de aula 7 do Departamento de Nutrição - DNUT/UFRN
TITLE:

Obesity and Habitual Nutrient Consumption in Adolescents with and without Metabolic Syndrome

KEY WORDS:

Adolescent, overweight, obesity, metabolic syndrome, hypertriglyceridemic waist, habitual consumption.

PAGES: 70
BIG AREA: Ciências da Saúde
AREA: Nutrição
SUMMARY:

The present study aims to objective to evaluate the frequency of Metabolic Syndrome (MetS) and its association with inadequate nutrient intake in overweight adolescents. This is a cross-sectional study, conducted by non-probabilistic sampling, with adolescents aged 10 to 19 years, of both sexes, diagnosed with overweight or obesity, who were first seen at the University Hospital pediatric endocrinology outpatient clinic. Onofre Lopes/UFRN, Natal/RN, from October 2016 to August 2019. Anthropometric, biochemical and food and dietary intake data were collected. The diagnostic criterion used for MetS was that established by the International Diabetes Federation (IDF), and for the Hypertriglyceridemia Waist (HW) waist circumference> P90 and triglycerides> 100 mg / dL. The usual intake of energy and nutrients was estimated through two 24-hour recalls (R24h). The prevalence of micronutrient inadequacy was estimated by the Estimated Average Requirement (EAR) as the cutoff point, with adjustments for intra and interpersonal and energy variances. Data distribution normality was verified by the Komolgorov-Smirnov test and Mann-Whitney U test for data that did not obtain normal distribution. Student's t-test for independent samples was used to verify differences in metabolic characteristics between adolescents with and without MetS, as well as between adolescents with and HW. From Pearson's chi-square test or Fisher's exact test, the binary association of the study variables with the MetS was verified. Variables that were associated with P ≤ 0.20 were considered to enter the Poisson Regression model. Poisson regression was used to verify the prevalence ratio and the 95% confidence interval between HW and MetS. The multicollinearity between the model variables was verified by Pearson's chi-square test. Omnibus test and AIC were used to verify the fit of the regression model. For all analyzes a P <0.05 was considered as statistically significant. Analyzes were performed on the SPSS version 25.0 statistical package (IBM®, Chicago, IL, USA). The final study sample consisted of 117 adolescents, with a higher percentage of males (53.8%) and a mean age of 11.4 ± 1.5 years. Regarding the anthropometric state, most had obesity (56.4%) with a mean BMI of 23.8 ±. The prevalence of MetS was 22.2%, while that of HW 42.7%. Significant differences were found between adolescents with and without MetS for HW (t (115) = -4.038; P <0.001), fasting glucose (t (33.649) = -2.233; P = 0.032), fasting insulin. (U (115) = 1707.0; P <0.001), HOMA-IR (U (114) = 1705.5; P <0.001) triglycerides (U (116) = 1860.0; P <0.001) and HDL- cholesterol (t (115) = 5.195; P <0.001). MetS was associated with anthropometric status (χ (2) = 14.928; P = 0.001), waist circumference (χ (2) = 13.133; P <0.001), fasting glucose (χ (2) = 19.486; P < 0.001), fasting insulin (χ (2) = 19.054; P <0.001), HOMA-IR (χ (2) = 17.870; P <0.001), HDL-cholesterol (χ (2) = 20.743; P <0.001) , serum triglycerides, both by the cutoff point for MetS (χ (2) = 29.498; P <0.001) and the cutoff point for HW (χ (2) = 11.112; P = 0.001), and associated with the HW ( χ (2) = 23.959; P <0.001). HW was associated with MetS independent of fasting glucose, HDL-cholesterol and serum triglycerides. The prevalence ratio between HW and MetS was 3.13 (95% CI, 1.21 to 8.12; P = 0.019). The average energy consumption in overweight adolescents ranged from 1674 Kcal / day in those aged 10 to 13 years and 1666 Kcal / day in adolescents aged 14 to 18 years. The average contribution percentage of carbohydrate intake was 52%, total fat 31%, protein 17%. The average fiber consumption was 16.5 g / day. There was a 100% prevalence of inadequacy for the following nutrients regardless of gender and age group: vitamin D, vitamin E, vitamin B12, folate, calcium. Considering age and sex, there was a high prevalence of inadequate intake of magnesium (95-99%), vitamin A (75-98%), vitamin B1 (81-99%), vitamin B2 (93-99%). ), vitamin B6 (97-99%), phosphorus (92-96%), copper (62-91%), zinc (46-72%) and iron (22-70%). When the sample was stratified by the presence or absence of MetS, there was an average energy and macronutrient consumption in adolescents with MetS of 1671.58 Kcal / day, 52.45% carbohydrate, 16.70% protein, 30, 85% total fat and 16.77 g / day of fiber; In those without MetS, the average energy consumption was 1686.16 Kcal / day, 51.26% carbohydrate, 17.35% protein, 31.38% total fat and 16.23 g / day. The prevalence of micronutrient inadequacy in both sexes was 100% for the following nutrients, regardless of the presence of MetS: vitamin D, vitamin E, folate, calcium, vitamin B12. In addition, high prevalences were found between the following ranges for the following nutrients, both in the sample with and without MetS: vitamin A (80.51 - 98.54%), vitamin B1 81.59 - 99.62%), vitamin A B2 (92.79 - 100%), vitamin B6 (96.86 - 99.78%), phosphorus (91.31 - 97.13%), magnesium (95.15 - 100%), copper (77.34) - 92.22%). In conclusion, the sample used in the study presented a high frequency of MetS, which correlated with anthropometric status, waist circumference, fasting glucose, HOMA-IR, HDL-c and triglycerides, as well as association with HWAdequacy of energy and macronutrient intake and high prevalence of inadequate intake of vitamins and minerals were observed regardless of the presence of MetS.

BANKING MEMBERS:
Externa à Instituição - DIRCE MARIA LOBO MARCHIONI
Interna - 2306763 - KARINE CAVALCANTI MAURICIO DE SENA EVANGELISTA
Presidente - 1452705 - SEVERINA CARLA VIEIRA CUNHA LIMA