Banca de QUALIFICAÇÃO: RAYANNE OLIVEIRA LOPES

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : RAYANNE OLIVEIRA LOPES
DATE: 05/12/2024
TIME: 09:00
LOCAL: Sessão pública realizada por videoconferência
TITLE:

Assessment of the impact of ultra-processed food consumption on vitamin E markers in adults and elderly people: BRAZUCA POST-COVID-19 study.

KEY WORDS:

Alpha-tocopherol. Micronutrients. Dietary intake. Population groups

PAGES: 61
BIG AREA: Ciências da Saúde
AREA: Nutrição
SUMMARY:

Vitamin E has antioxidant properties that protect cells against oxidative damage, thus preventing the occurrence of non-communicable diseases (NCDs). Evidence suggests that a higher intake of ultra-processed foods (UPF) may lead to lower circulating levels of alpha-tocopherol in lactating women, but it is still unknown if this relationship is present in populations at risk for NCDs. In this context, this study aimed to analyze the relationship between UPF consumption and vitamin E concentrations in serum and diet among adults and older adults, addressing a research gap and its possible implications for health and nutritional status. The study was a cross-sectional analysis based on sampling from the “BRAZUCA POST-COVID-19” cohort in Natal/RN. Participants included adults and older adults of both genders, with socioeconomic, anthropometric, and dietary intake data collected (through two 24-hour recalls), along with blood samples for the extraction and analysis of serum alpha-tocopherol using Ultra-Performance Liquid Chromatography with Diode-Array Detection (UPLC-DAD). Values ⦤ 12 µmol/L were considered indicative of vitamin E deficiency (VED), and < 30 µmol/L as indicative of inadequate serum levels. Alpha-tocopherol data were adjusted by total cholesterol (TC) levels (µmol/mg). Partially, for qualification purposes, data from 68 participants were analyzed, of whom 67.6% were women. The mean age was 44.5 years (SD=11.3) for adults and 70.6 years (SD=6.1) for older adults. The majority of the population (63.2%) was composed of Black, Brown, or Indigenous individuals, while only 17.6% had incomes below the World Bank threshold, and 17.6% were smokers. Low education was observed in 45.6% of participants, being more common among the elderly (62.2%). Among adults, there was a higher level of education, with 51.6% having completed high school and 19.4% higher education (p=0.001). The concentration of alpha-tocopherol ([ ]-alpha-TOH) had a mean (SD) of 12.1 (9.2) µmol/L in adults and 12.2 (6.6) µmol/L in older adults. Overall, there was a 58.8% prevalence of VED and 97.1% inadequacy in serum alpha-tocopherol levels. Dietary intake data will be evaluated up to the defense. Foods will be classified according to the NOVA system and assessed in terms of the relative contribution of UPF in the diet, weight, and frequency of UPF intake. The dietary vitamin E profile will be evaluated, with a dietary adequacy threshold of 12 mg/day. Regression equations will be conducted to assess the association between variables, considering outcome variables as [ ]-alpha-TOH (µg/dL or µmol/mg), dietary vitamin E (mg/day), Vitamin E Deficiency (yes), Vitamin E inadequacy (yes), and UPF participation (%kcal) as the exposure variable. The contributions of this study will be innovative in evaluating the impact of UPF on the nutritional status of a micronutrient important for cardiovascular health and NCD prevention.

COMMITTEE MEMBERS:
Externa à Instituição - ANA GABRIELLA COSTA LEMOS DA SILVA - UFERSA
Externa ao Programa - 2374737 - INGRID WILZA LEAL BEZERRA - nullPresidente - 2578592 - KARLA DANIELLY DA SILVA RIBEIRO RODRIGUES