Association between toxoplasmosis and pre and postpartum depression in
women living in the municipality of SANTA CRUZ - RN
Toxoplasmosis, postpartum depression, puerperium, risk factor.
Toxoplasmosis is a zoonosis with a worldwide geographic distribution, affecting all continents despite
climatic variations. The clinical manifestations in a large part of the population are mild or in many cases
subclinical, making it a neglected disease. However, toxoplasmosis presents serious cases in
UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE
PROGRAMA DE PÓS-GRADUAÇÃO EM BIOLOGIA PARASITÁRIA
DEPARTAMENTO DE MICROBIOLOGIA E PARASITOLOGIA
immunocompromised individuals and also in pregnant women through vertical transmission due to the
damage it can cause to the development of the newborn. In addition, studies related to postpartum depression
have shown that latent toxoplasmosis is associated with behavioral changes and neuropsychiatric disorders.
It cannot be said that this includes postpartum depression. In view of this, we evaluated the hypothesis of an
association between Toxoplasma gondii infection and pre and postpartum depression. In this study, we
conducted a population-based cross-sectional survey of women in the gestational period, living in the
municipality of Santa Cruz, in the interior of the State of Rio Grande do Norte, assessed at two time points:
at the end of the third trimester of pregnancy and postpartum. To assess depressive symptoms, we used the
Edinburgh Postpartum Depression Scale (EPDS), a 10-item instrument validated for use in both pregnancy
and the puerperium. A sociodemographic questionnaire structured for this study was used to determine the
profile and epidemiologic aspects of toxoplasmosis. Data were tabulated in the Epidata program and
analyzed using STATA.