Banca de QUALIFICAÇÃO: MARIA KAROLAINY DO NASCIMENTO

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : MARIA KAROLAINY DO NASCIMENTO
DATE: 18/10/2024
TIME: 14:00
LOCAL: REMOTO: HTTPS://MEET.GOOGLE.COM/GIQ-VABQ-AXV
TITLE:

Exploring the role of body mass index-adjusted calf circumference within the SARC-CalF screening tool among older patients with cancer

KEY WORDS:

Sarcopenia screening; Calf circumference; Body mass index; Cancer; Mortality

PAGES: 6
BIG AREA: Ciências da Saúde
AREA: Nutrição
SUMMARY:

Introduction The study aimed to assess and compare the frequency of positive scores using unadjusted SARC-CalF with the scores derived from SARC-CalF after adjusting calf circumference (CC) for body mass index (BMI). The secondary aim was to assess the prognostic value of SARC-CalF after BMI adjustment, for length of hospital stay (LOS) and mortality. Methods This secondary analysis of a prospective cohort study, included both outpatients and inpatients of an oncology unit hospital in Brazil. BMI and CC were measured. Patients with excess weight had their CC adjusted for BMI by subtracting 3 cm, 7 cm, and 12 cm from the unadjusted CC values for respective BMI categories. SARC-CalF was used to screen for sarcopenia. Scores ≥11 were indicative of sarcopenia, considering both unadjusted and BMI-adjusted CC values. Clinical outcomes included prolonged LOS and both short- and long-term mortality. Results Our study included 206 subjects, with a median age of 69 years, and the majority were males (52.1%). The prevalence of low CC increased from 65% to 84% after BMI adjustment. Positive unadjusted SARC-CalF scores (≥11) were observed in 51% of the population and this prevalence increased to 65% using BMI-adjusted SARC-CalF criteria (≥11). Higher scores on BMI-adjusted SARC-CalF but not unadjusted SARC-CalF were independently associated with prolonged LOS [adjusted HR: 1.26 (1.03-1.53)], and 6-month mortality [adjusted HR: 1.42 (1.07-1.87)]. Both unadjusted and BMI-adjusted SARC-CalF were independently associated with 12-month mortality. Conclusion BMI-adjusted SARC-CalF may be a promising strategy to enhance the detection of older patients with cancer and excess weight at risk of sarcopenia, and it may serve a dual role as a prognostic tool, as it was independently associated with prolonged LOS and mortality

COMMITTEE MEMBERS:
Presidente - 1879430 - ANA PAULA TRUSSARDI FAYH
Externa à Instituição - FLÁVIA MORAES SILVA - UFCSPA
Externa ao Programa - 2306763 - KARINE CAVALCANTI MAURICIO DE SENA EVANGELISTA - null