Banca de QUALIFICAÇÃO: YASMIN FERREIRA DA CRUZ

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : YASMIN FERREIRA DA CRUZ
DATE: 25/07/2026
TIME: 10:00
LOCAL: REMOTA - https://meet.google.com/jxv-fyck-bqr
TITLE:

DEVELOPMENT OF FACIAL BOOSTER MICROEMULSION USING THE BOX-BEHNKEN DESIGN

KEY WORDS:

Nanotechnology; Microemulsion; Facial booster; Multifunctional cosmetic; Experimental design.

PAGES: 23
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUMMARY:

The international cosmetic market has been highlighted for the production and commercialization of multifunctional products, characterized by presence of several active ingredients. Then, the development of microemulsions (ME) as a cosmetic product stands out due to its ability to deliver different active ingredients to obtain properties as moisturizing, photoprotective and antioxidant. Based on this, the aim of this study was to produce and characterize a multifunctional facial booster (MFB) based on a Linum Usitatissimum (Linseed) Seed Oil ME containing Tocopherol, Hyaluronic Acid (HA), and Phenylbenzimidazole Sulfonic Acid (PBSA) by the Box-Benhken experimental design (BBD). The active ingredients concentrations were defined based on the BBD results of antioxidant activity, sun protector factor (SPF) and occlusivity. The MFB was characterized by its antioxidant activity, occlusivity, SPF and spreadability in vitro. In addition, MFB was physicochemically characterized by hydrodynamic droplet size distribution, polydispersity index (PdI) and pH. The BBD proposed a MFB composed by HA 5 %, Tocopherol 5 % and PBSA 7.5 %, that showed an antioxidant activity, SPF, occlusivity and spreadability of 8.02 ± 1.20 %, 12.65 ± 1.33, 27.65 ± 1.67 % and 2923 ± 167 mm², respectively. These results represent an effective radical scavenging ability, photoprotection, water loss prevention and adequate spreadability. Moreover, MFB showed a droplet size, PdI and pH of 34.74 ± 0.14 nm, 0.184 ± 0.02, 7.14 ± 0.02, respectively. The MFB showed physicochemical characteristics suitable for microemulsion systems and presented suitable stability for 90 days. Finally, the MFB was successfully produced and stands itself as a promising multifunctional cosmetic product.

COMMITTEE MEMBERS:
Presidente - 1178187 - ERYVALDO SOCRATES TABOSA DO EGITO
Externa à Instituição - FRANCELINE REYNAUD - UFRJ
Externa ao Programa - 2569445 - LOURENA MAFRA VERISSIMO - null