Banca de QUALIFICAÇÃO: AMANDA ALMEIDA GOMES DANTAS

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : AMANDA ALMEIDA GOMES DANTAS
DATE: 20/12/2024
TIME: 09:00
LOCAL: REMOTA - HTTPS://MEET.GOOGLE.COM/QHK-NSUW-GBH
TITLE:

INEQUALITIES IN DIAGNOSIS AND MORTALITY FROM COLORECTAL CANCER IN BRAZIL

KEY WORDS:

Colorectal cancer; Diagnosis; Mortality; Social determinants of health; Health inequalities;

PAGES: 56
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Advanced stage diagnosis and mortality from colorectal cancer (CRC) may be related to individual factors, socioeconomic conditions , and healthcare service availability. The objective of the study was to analyze the prevalence of advanced stage CRC at the time of diagnosis and its association with individual, contextual, socioeconomic, and healthcare service indicators. The objective of the study was to analyze the prevalence of advanced stage and the spatial distribution pattern of advanced stage diagnosis and mortality from CRC in Brazil and its relationship with population socioeconomic indicators and healthcare service availability. For the diagnosis of advanced stage was carried out an observational, cross-sectional study was conducted, analyzing cases of malignant neoplasms of the colon and rectum in individuals of both sexes, aged between 18 and 99 years, diagnosed between 2010 and 2019 in Brazil (n=69,047), and the spatial analysis was carried out based on the 133 Intermediate Regions of Urban Articulation in the Brazilian territory in the period from 2015 to 2019 (n =34,454). Staging, mortality, socioeconomic, and healthcare service availability data were collected from information systems. A Multilevel Poisson Regression model with random intercept was used. The prevalence of advanced stage CRC at diagnosis was 65.6%. Advanced stage was associated with older age groups prevalence ratio (PR) 4.40 and younger age groups (PR 1.84), low Human Development Index (HDI) (PR 1.22), and low density of family health strategy teams (PR 1.10). A spatial analysis was performed using the Global Moran's Index and Local Indicator of Spatial Association. In the multivariate analysis, models with global spatial effects, the Spatial Error, were utilized. The proportion of advanced-stage diagnosis of colorectal cancer for females was 64.7%, and for males, it was 65.9%. The adjusted mortality rate for colorectal cancer was 11.25 for females and 14.29 for males per 100,000 inhabitants. The adjusted mortality rates for colorectal cancer were associated with the social vulnerability index, general practitioner density, colorectal specialist density, and specialized oncology services. The study highlights the unequal distribution of social determinants of health in advanced stage diagnosis and mortality from CRC in Brazil, demonstrating the need to evaluate and reorient public policies to improve early detection and prevention achieve significant advances in the search for health equity in the results for these conditions in the country

COMMITTEE MEMBERS:
Presidente - 3926907 - DYEGO LEANDRO BEZERRA DE SOUZA
Interna - 2495705 - GRASIELA PIUVEZAM
Externa ao Programa - 2305247 - ISABELLE RIBEIRO BARBOSA MIRABAL - null