Banca de QUALIFICAÇÃO: ROBERTO MORENO MENDONCA

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : ROBERTO MORENO MENDONCA
DATE: 18/11/2024
TIME: 09:00
LOCAL: REMOTO: HTTPS://MEET.GOOGLE.COM/EHU-PQTE-BIG
TITLE:

Demystifying the Relationship Between Breast Vascular Calcifications and Cardiovascular Risk: An Evidence-Based Analysis

KEY WORDS:

Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Mammography; Risk Factors; Tomography

PAGES: 29
BIG AREA: Ciências da Saúde
AREA: Medicina
SUMMARY:

Objectives: To evaluate whether breast vascular calcifications identified on screening mammograms play a role in the cardiovascular risk stratification of the female population, using the coronary calcium score, the primary non-traditional cardiovascular risk stratifier, for this analysis. Subject of questions in the medical literature, if this association is proven, mammography could be given an additional role, supporting the adoption of preventive measures.

Methods: This cross-sectional observational study was based on the analysis of screening mammograms performed at the Maternidade Escola Januario Cicco / Federal University of Rio Grande do Norte between August 2022 - November 2023. Patients with identified breast vascular calcifications on mammograms were referred for data collection and computed tomography to assess the coronary calcium score. The data were tabulated and submitted to descriptive, exploratory, and inferential statistical analysis.

Results: A total of 151 women completed the study. The association between the presence of BVCs and elevated coronary calcium scores was not statistically significant (p=0.341), even after logistic regression (p=0.78). Among the variables studied, which included anthropometric, socioeconomic factors and traditional cardiovascular risk factors, the variables that showed significant positive association with elevated coronary calcium scores were age (p=0.038), presence of systemic hypertension (p=0.004), diabetes mellitus (p=0.012), dyslipidemia (p=0.021), and chronic kidney disease (p=0.007).

Conclusions: No significant association was demonstrated between the presence of breast vascular calcifications identified on screening mammograms and elevated cardiovascular risk when assessed by coronary calcium scoring. Therefore, there is no justification to infer elevated cardiovascular risk based on the presence of vascular calcifications on routine mammograms

COMMITTEE MEMBERS:
Interno - 346138 - ALDO DA CUNHA MEDEIROS
Presidente - 1199080 - ANA KATHERINE DA SILVEIRA GONCALVES DE OLIVEIRA
Externo ao Programa - 2682821 - EDUARDO CALDAS COSTA - null