Dietary total antioxidant capacity and polyphenol intake are not associated with metabolic parameters in patients with metabolic syndrome.
Metabolic syndrome; diet, polyphenols; antioxidants; bioactive compounds.
The dietary total antioxidant capacity (DTAC) and dietary polyphenols intake (DPI) are associated with improved metabolic profiles across various populations; however, studies involving individuals with metabolic syndrome (MetS) are limited. Our hypothesis is that antioxidant and polyphenol intake would be associated with improvements in MetS components and inflammatory markers in individuals with MetS. This study included 224 individuals diagnosed with MetS according to the National Cholesterol Education Program Adult Treatment Panel III, aged between 19 and 77 years, of both sexes, recruited from a university hospital in northeastern Brazil. Sociodemographic and clinical data were collected, along with two 24-hour dietary recalls (24h-R) to assess dietary intake. The DTAC was estimated based on data from the literature and The Antioxidant Food Table created by Carlsen et al. (2010). DPI was estimated using literature data and the Phenol-Explorer and USDA databases. Linear models were used to evaluate the association of DTAC and DPI with triglycerides, fasting glucose, HDL-c, waist circumference, blood pressure, and high-sensitivity C-reactive protein. Coffee was the primary source for both DTAC and DPI values. The phenolic acid and flavonoid classes contributed the most to total polyphenol intake. No significant association was found between DTAC, DPI, and the MetS components or hs-CRP. Additional studies are needed to further understand the investigated dietary factors and their impact on metabolic health, especially in individuals with MetS.