Banca de QUALIFICAÇÃO: POLYANA ALBANO NÓBREGA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : POLYANA ALBANO NÓBREGA
DATE: 03/03/2026
TIME: 07:50
LOCAL: Sala de Reuniões
TITLE:

Effect of nutritional therapy with pasteurized human milk on the adequacy of the diet of premature newborns: a randomized controlled clinical trial.

KEY WORDS:

Enteral Nutrition; Milk Banks; Intensive Care Units, Neonatal; Infant, Low Birth Weight.

PAGES: 61
BIG AREA: Ciências da Saúde
AREA: Nutrição
SUMMARY:

Breast milk is considered the gold standard for nourishing preterm newborns (PTNB). However, achieving nutritional adequacy through enteral nutritional therapy remains a challenge in Neonatal Intensive Care Units (NICU), especially given the physiological limitations and low volumetric tolerance of these newborns. In this scenario, the management of pasteurized human milk (PHM), considering its variability, emerges as a strategy to optimize nutritional delivery for PTNBs, which may favor a faster achievement of the nutritional intake goals established by guidelines for this population. Therefore, the present study aimed to evaluate the effect of nutritional therapy with colostrum PHM followed by hypercaloric PHM on the dietary adequacy of PTNBs through a randomized, blinded, and controlled clinical trial. Participants were randomized and allocated into two groups: the control group, which received expressed maternal milk (EMM) and normocaloric PHM; and the intervention group, which received EMM and colostrum PHM until reaching a volume of 100 mL/kg/day, followed by hypercaloric PHM (≥70 kcal/100ml). Interventions were maintained until NICU discharge or changes in medical prescription. The administered diet was monitored weekly (at 7, 14, and 21 days of follow-up, and at NICU discharge) through medical records, with data collection regarding volume, frequency, type of diet, and administration route. Nutritional adequacy was assessed by the attainment of recommendations for volume, energy, protein, and lipids through enteral nutritional therapy during the PTNB’s stay in the NICU. The intervention lasted an average of 18,27 ± 9,52 days. Although no significant differences were found in the evolution of dietary intake between groups, the intervention group showed a longer duration of EMM use (p = 0.002). The dietary adequacy analysis showed that both groups exceeded the adequacy target for energy and lipids at the time of NICU discharge. It is concluded that, so far, both PHM interventions appear to provide an adequate dietary evolution for PTNBs. However, the early use of colostrum with hypercaloric PHM appears to be effective in protecting breastfeeding at NICU discharge.

COMMITTEE MEMBERS:
Externa à Instituição - EVA DEBORA DE OLIVEIRA ANDRADE - UNIFACEX
Presidente - 2578592 - KARLA DANIELLY DA SILVA RIBEIRO RODRIGUES
Interna - 2315640 - MARCIA MARILIA GOMES DANTAS LOPES