Banca de DEFESA: KAYONARIA KARDENIA ALVES DA COSTA GOMES

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : KAYONARIA KARDENIA ALVES DA COSTA GOMES
DATE: 27/02/2025
TIME: 09:00
LOCAL: Sala de Aulas II GEP/MEJC
TITLE:

HPV E6/E7 mRNA for cervical cancer screening with self- collected samples: a protocol for a systematic review.

KEY WORDS:

SELF-COLLECTION - mRNA E6 and E7- HPV - CERVICAL CANCER SELF

PAGES: 63
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Cancer is associated with high-risk HPV. E6/E7 oncoproteins are highly expressed in high-risk HPV. Self-collection is a screening method that allows women to collect their own samples for HPV detection, and has been considered a promising alternative to screening for cervical cancer. This study aimed to evaluate the association between HPV E6/E7 mRNA and cervical cancer in self-collected samples. The systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive search was performed in the PubMed, Embase, Scopus, Web of Science and LILACS databases, with no restrictions on language or publication period. Cross-sectional studies involving the detection of HPV E6/E7 mRNA in self-collected cervical cancer samples were included. Study selection and data extraction were conducted independently by two reviewers. Risk of bias assessment was performed using the Joanna Briggs Institute (JBI) tool for cross-sectional studies. This systematic review aims to assess whether mRNA expression of E6 and E7 oncoproteins via cervical self- collection can be used in cervical cancer screening.

COMMITTEE MEMBERS:
Presidente - 3313589 - JANAINA CRISTIANA DE OLIVEIRA CRISPIM FREITAS
Interna - 1199080 - ANA KATHERINE DA SILVEIRA GONCALVES DE OLIVEIRA
Externo à Instituição - KLEYTON SANTOS DE MEDEIROS - LNRCC