Banca de DEFESA: THAYANNE GURGEL DE MEDEIROS MENDES

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : THAYANNE GURGEL DE MEDEIROS MENDES
DATE: 27/02/2025
TIME: 09:00
LOCAL: Sala de Aulas II GEP/MEJC
TITLE:

Impact of Gestational Hypertensive Syndromes on nutritional and clinical outcomes in preterm newborns: a prospective cohort

 

KEY WORDS:

Hypertensive disorders in pregnancy, Preterm infant, Nutritional therapy, Neonatal intensive care unit

 

PAGES: 60
BIG AREA: Ciências da Saúde
AREA: Nutrição
SUMMARY:

Hypertensive syndromes in pregnancy (HGS) are characterized by changes in blood pressure levels during the gestational period. For children of women with HGS, premature birth is one of the main consequences, which can impact neonatal outcomes. The objective of this research was to compare the nutritional outcomes of preterm newborns (PTNB) born to women with HGS to children of normotensive women. The study was a prospective cohort study with a quantitative approach. The study participants were PTNBs born at the Januário Cicco Maternity School, in Natal-RN, from October 2021 to November 2023 who were hospitalized in the neonatal intensive care unit (NICU). PTNBs with gestational age between ≥23 and <37 weeks and weight less than 2500g were included, and neonates diagnosed with severe congenital malformation or inborn errors of metabolism were excluded. The PTNBs were divided into 2 groups, according to exposure to HGS. Data collection was performed using electronic medical records and statistical analysis was performed using SPSS version 28.0. Of the 220 pregnant women monitored, half had GHS. There was a significant statistical association between GHS and maternal age >35 years (p=0.013) and cesarean delivery (p<0.01). Preterm infants born to women with GHS had a greater need for parenteral nutrition (p=0.017) and a higher risk of inadequate enteral nutrition (p=0.020). Furthermore, children born to women with GHS had a higher prevalence of being classified as small for gestational age at birth (p<0.001) and, upon discharge from the NICU, with extrauterine growth restriction (p=0.018), when compared to children born to normotensive women. The results confirm that GHS are associated with unfavorable nutritional outcomes in preterm infants. Children of women with GHS had difficulty maintaining adequate nutritional status, with lower Z-scores at birth and at discharge from the NICU. Therefore, children of women with GHS require early and individualized nutritional interventions to improve recovery and growth during their stay in the NICU.

COMMITTEE MEMBERS:
Externa à Instituição - CLAUDIA SAUNDERS - UFRJ
Externa ao Programa - 1755394 - JULIANA FERNANDES DOS SANTOS DAMETTO - nullPresidente - 2315640 - MARCIA MARILIA GOMES DANTAS LOPES
Externa ao Programa - 4220250 - NIVIA MARIA RODRIGUES ARRAIS - null