Banca de QUALIFICAÇÃO: ANA CAROLINA MACEDO DA SILVA DIAS

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
DISCENTE : ANA CAROLINA MACEDO DA SILVA DIAS
DATA : 31/10/2019
HORA: 14:00
LOCAL: DISCIPLINA DE PATOLOGIA ORAL
TÍTULO:
ANALYSIS OF OXIDATIVE DNA DAMAGE IN ORAL PLANE THROUGH 8-HYDROXY-2'-DEOXIGUANOSINE IMMUNOISTOCHEMICAL EXPRESSION


PALAVRAS-CHAVES:

Lichen Planus; Oxidative Stress; DNA damage; Immunohistochemistry.


PÁGINAS: 36
GRANDE ÁREA: Ciências da Saúde
ÁREA: Odontologia
RESUMO:

Oral Lichen Planus (OLP) is an immunologically mediated chronic mucocutaneous disease that is relatively common in the dental clinic. Several researches have been conducted to identify pathogens of this lesion, since it is still unknown, standing out as researches that use oxidative stress biomarkers, suggesting an important relationship of oxidative stress in OLP. Among these biomarkers is the 8-hydroxy-2'-deoxyguanosine (8-OHdG), which is generated after oxidative DNA damage. In this context, the objective of this research is to evaluate the oxidative damage of DNA in OLP through the immunohistochemical expression of 8-OHdG, to verify if this mechanism may be involved in the pathogenic of this lesion. An observational cross-sectional study will be performed, which will be evaluated the 8-OHdG immunoexpression in OLP and correlates with its clinical-pathological aspects.


MEMBROS DA BANCA:
Interna - 2492713 - ERICKA JANINE DANTAS DA SILVEIRA
Interna - 2644142 - PATRICIA TEIXEIRA DE OLIVEIRA
Presidente - 350484 - ROSEANA DE ALMEIDA FREITAS
Notícia cadastrada em: 22/10/2019 17:03
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