Banca de DEFESA: WESLLEY QUIRINO ALVES DA SILVA

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : WESLLEY QUIRINO ALVES DA SILVA
DATE: 15/12/2023
TIME: 09:00
LOCAL: REMOTA - https://meet.google.com/vbu-bkjc-jpm?hs=122&authuser=0
TITLE:

Self-regulation of the prefrontal cortex and its relationship with physical exercise tolerance and body fat accumulation

KEY WORDS:

Keywords: Brain; Physical Activity; Cognition; Sedentary Lifestyle; Exercise Tolerance; Fatigue.

PAGES: 119
BIG AREA: Ciências da Saúde
AREA: Educação Física
SUMMARY:

Physical inactivity is considered one of the major global public health issues, and understanding its effects is crucial for developing effective behavioral prevention and health intervention strategies. Addressing this health problem, the overall objective of this thesis is to investigate the complex connection between body, mind, and brain during physical exercise. This thesis comprises three chapters that explore the neurobiological aspects of physical inactivity, overweight, and obesity, providing a deeper understanding of these issues and their significance for global health. The first chapter presents a comprehensive review of the neurobiological factors influencing the maintenance of inactive behavior in overweight and obese individuals, highlighting the complex interaction between brain structures such as the limbic system and executive control in decision-making related to physical activity. Moreover, a behavioral model with potential implications in the maintenance and modulation of physical activity behavior is proposed. The second chapter explores the relationship between prefrontal cortex (PFC) hemodynamics, inhibitory control, and exercise performance in overweight or obese individuals. The findings suggest that low PFC oxygenation is associated with poor exercise performance, and that impaired inhibitory control may mediate this relationship. The third chapter investigates the relationship between body fat accumulation, neurovascular coupling (NVC) efficiency, and exercise tolerance. We found that the relationship between body fat and intolerance can be explained by NVC, underlying the PFC's reduced ability to convert hemodynamic responses into inhibitory control to tolerate exercise in physically inactive youths with accumulated fat mass. Although this fact seems to limit the self-regulation of body sensation perception, it brings predictions about the anticipated interruption of exercise. Additionally, interoceptive dimensions of higher distraction and low self-regulation in physically inactive individuals with accumulated fat mass may predict exercise intolerance. The comprehensive knowledge integrating brain responses and exercise tolerance in a sedentary population with high fat accumulation generated by this thesis provides new evidence that underpins the development of intervention strategies for promoting physical activity and combating obesity, thereby enhancing the quality of life of the population

COMMITTEE MEMBERS:
Externo à Instituição - EDSON FILHO
Externo ao Programa - 1696755 - BRUNO LOBAO SOARES - nullPresidente - ***.870.938-** - EDUARDO BODNARIUC FONTES - UNICAMP
Externo à Instituição - GLEBER PEREIRA - UFPR
Externo ao Programa - 1989744 - HASSAN MOHAMED ELSANGEDY - null