Banca de QUALIFICAÇÃO: LINDUARTE VARELA DE MORAIS
Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.STUDENT : LINDUARTE VARELA DE MORAIS
DATE: 10/10/2022
TIME: 09:30
LOCAL: REMOTA - https://meet.google.com/akt-ynha-mua
TITLE:
IMMUNOPHENOTYPING IN A POPULATION OF BLOOD DONORS APPLIED TO TRANSFUSION MEDICINE.
KEY WORDS:
Blood donors; Immunophenotyping; Blood Group Antigens
PAGES: 30
BIG AREA: Ciências da Saúde
AREA: Medicina
SUMMARY:
Objective: To determine the immunophenotyping of a population of blood donors, intended to build a database for transfusion medicine. Show the importance of erythrocyte immunophenotyping as prevention of alloimmunization. Method: A cross-sectional study was carried out on 11,664 blood donors for the ABH system typing and of these, 1255 blood donors were selected randomly for the determination of blood group antigens of the Rh system and Kell antigen. Blood centrifugation methods, centrifuge hemolysis tube test and indirect Coombs test were used for blood typing. The results obtained were compared by the Chi-square test. A level of statistical significance of p ≤ 0.05 was considered. Results: Antigenic frequencies for the ABH system found: the frequency found for the blood group O 48.8%, the frequency found for the blood group A 35.4%; the frequency found for the blood group B 10.6% and the frequency found for the blood group AB 3.2%. In the Rh-Hrsystem the most frequent antigens found: e 94.5%,D 88.9%; c 80.6; C 56.4%; E 26.3%. For the Kell antigen, the frequency found was 6.7%. The most frequent phenotypes found were DCcee 23.3%; ddccee 18.1%, DCCee 16.7%; Dccee11.0%; DCcEe 10.2% and DccEe 8.8%. The lowest frequency was found: DCcEE 0.64% and ddCcEe 0.08%. Conclusion: The antigenic and phenotypic frequencies found, shows the importance of immunophenotyping these blood group antigens in order to transfuse them, making them as compatible as possible, decreasing the risk of alloimmunization.
COMMITTEE MEMBERS:
Externo ao Programa - 346138 - ALDO DA CUNHA MEDEIROS - nullExterno ao Programa - 6349161 - GERALDO BARROSO CAVALCANTI JUNIOR - nullExterna ao Programa - 350753 - VALERIA SORAYA DE FARIAS SALES - null