Banca de DEFESA: ANGÉLICA KERCYA PEREIRA DE MENDONÇA

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : ANGÉLICA KERCYA PEREIRA DE MENDONÇA
DATE: 28/06/2021
TIME: 08:00
LOCAL: Plataforma google meet
TITLE:

ANTIMICROBIAL AND ANTIBIOFILM POTENTIAL OF THE HYDROETHANOLIC EXTRACT OF THE MOMBIN L SPONDIAS LEAF AND ITS FRACTIONS AGAINST SUPERINFECTANT MICROORGANISMS OF THE ORAL ENVIRONMENT

KEY WORDS:

Antimicrobial activity; Spondias mombin L .; Antibiofilm.

PAGES: 65
BIG AREA: Ciências da Saúde
AREA: Odontologia
SUBÁREA: Clínica Odontológica
SUMMARY:

The chemical control of oral biofilm acts as an auxiliary method of mechanical control for the maintenance and/or restoration of oral health, also acting on other microorganisms that are not local residents of the oral microbiota. In this context, the literature already reports that many superinfecting microorganisms can be present in the oral biofilm and thus contribute to the occurrence of more serious systemic infections. Therefore, herbal medicines have demonstrated a wide variety of biological activities, especially antimicrobial activity. Therefore, the present study aimed to evaluate the antimicrobial and antibiofilm action of the hydroethanolic extract of Spondias mombin L. and its fractions of phenolic acids, flavonoids and tannins against superinfecting microorganisms (Pseudomonas aeruginosa, Enterococcus faecalis, Staphylococcus aureus and Escherichia coli). For this, the Minimum Inhibitory Concentration by the disk-diffusion technique and by the microdilution technique in microplates, the Antibiofilm Effect of the fractions under the formation of biofilm and in preformed biofilms (monospecies and multispecies), the Minimum Inhibitory Concentration of Adherence and Bactericidal Kinetics of the extracts mentioned, using as control 0.12% chlorhexidine gluconate, in triplicate. The results showed that the hydroethanolic extract exhibited superior antimicrobial and antibiofilm effect when compared to the action of its fractions. Comparing the control group with the action of the hydroethanolic extract, similar results were observed between them. Thus, it is possible to conclude that the hydroethanolic extract has antimicrobial and antibiofilm action similar to 0.12% chlorhexidine gluconate and superior to the studied fractions.

BANKING MEMBERS:
Presidente - 1958729 - RUTHINEIA DIOGENES ALVES UCHOA LINS
Interna - 2492713 - ERICKA JANINE DANTAS DA SILVEIRA
Interno - 1879551 - FABIO ROBERTO DAMETTO
Externo à Instituição - EDJA MARIA MELO DE BRITO COSTA - UEPB
Externo à Instituição - PEDRO HENRIQUE SETTE DE SOUZA - UPE