Banca de QUALIFICAÇÃO: ANGÉLICA KERCYA PEREIRA DE MENDONÇA

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : ANGÉLICA KERCYA PEREIRA DE MENDONÇA
DATE: 10/05/2021
TIME: 14:00
LOCAL: Plataforma google meet
TITLE:

ANTIMICROBIAL AND ANTIBIOFILM POTENTIAL OF SPONDIAS MOMBIN L. EXTRACT FRACTIONS AGAINST SUPERINFECTANT MICROORGANISMS

 

KEY WORDS:

Antimicrobial activity; Spondias mombin L .; Antibiofilm.

PAGES: 40
BIG AREA: Ciências da Saúde
AREA: Odontologia
SUBÁREA: Clínica Odontológica
SUMMARY:

Chemical control of oral biofilm acts as an auxiliary method of mechanical control for the purpose of maintaining and / or restoring oral health, also acting on other microorganisms that are not local residents of the oral microbiota. In this context, the literature already reports that many superinfecting microorganisms may be present in the oral biofilm and thus contribute to the occurrence of more serious systemic infections. Therefore, herbal medicines have demonstrated a wide variety of biological activities, especially antimicrobial activity. Therefore, the present study sought to evaluate the antimicrobial and antibiofilm action of the fractions of phenolic acids, flavonoids and tannins of the hydroethanolic extract of Spondias mombin L. against superinfecting microorganisms (Pseudomonas aeruginosa, Enterococcus faecalis, Staphylococcus aureus and Escherichia coli). For this, the Minimum Inhibitory Concentration was investigated by the disk-diffusion technique and by the microplate microdilution technique, the Determination of the Microbial Death Curve, the Minimum Adhesive Inhibitory Concentration and the Antibiofilm Effect of the fractions under the formation of biofilm and biofilms preforms of the aforementioned extracts, using 0.12% chlorhexidine digluconate as a control, in triplicate. It was observed that the extracts of the fractions have antimicrobial activity, non-stick effect and antibiofilm activity, however 0.12% chlorhexidine digluconate remains the best option of choice for microbial control of the oral cavity.

BANKING MEMBERS:
Presidente - 1958729 - RUTHINEIA DIOGENES ALVES UCHOA LINS
Interno - 1879551 - FABIO ROBERTO DAMETTO
Externa ao Programa - 3138832 - MARIA REGINA MACEDO COSTA