Banca de DEFESA: LILIANE CRISTINA NOGUEIRA MARINHO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : LILIANE CRISTINA NOGUEIRA MARINHO
DATE: 06/08/2020
TIME: 09:00
LOCAL: Remoto
TITLE:

HEALTH QUALITY ASSESSMENT THROUGH PHOTOBIOMODULATION FOR THE PREVENTION AND TREATMENT OF ORAL MUCOSITIS IN PATIENTS SUBMITTED TO HEMATOPOIETIC STEM CELL TRANSPLANTATION

KEY WORDS:

Protocol; Photobiomodulation; Low power laser therapy; Oral mucositis; Hematopoietic stem cell transplantation.

PAGES: 72
BIG AREA: Ciências da Saúde
AREA: Odontologia
SUBÁREA: Clínica Odontológica
SUMMARY:

Introduction: Oral mucositis (OM) is an inflammation of the oral mucosa, quite prevalent in patients undergoing Hematopoietic Stem Cell Transplantation (HSCT), contributing to the interruption of antineoplastic treatment. Photobiomodulation therapy (PBM) has been proposed due to its preventive and therapeutic action for OM. Objective: To evaluate the quality of health care through the process and result of photobiomodulation protocols in the prevention and treatment of OM in patients undergoing HSCT. Materials and methods: Observational, descriptive, prospective and health quality assessment study, appropriate according to Squire 2.0. The sample consisted of thirty-six patients who received previous dental treatment and PBM as a preventive protocol for oral mucositis. When diagnosed with mucositis, patients received therapeutic PBM. The patients were followed up and evaluated during the conditioning regime (T0), one day after HSCT (T1), with 5 days after HSCT (T2) and with 10 days after HSCT (T3). The following indicators were used to evaluate the process: Evidence-based therapy, Assessment and recording of symptoms at all visits, Preventive care with PBM during hospitalization and Therapeutic plan for the outbreak of symptoms and worsening. The result indicators were expressed in percentages, being the Percentage of individuals who developed: OM; OM according to gravity; Ache; Severe, mild and / or moderate pain; Oral changes; OM according to sex; OM in leukopenic individuals. In addition to using painkillers during therapy; Pain reduction; Presence of another associated treatment; Individuals with comorbidities who developed OM and Individuals with autologous and allogeneic transplants who developed OM. Descriptive and statistical analysis of the indicators was performed using the non-parametric Wilcoxon test and the Chi-square test with a significance level of 5%. Results: For the process, it was observed that in all indicators, 100% of the sample obtained assistance within the desirable standard. Result indicators showed that 66.6% of patients had Oral Mucositis in at least one follow-up period, with a statistically significant increase between times T1 and T2, as well as between times T1 and T3 (p <0.05), with a predominance grade I (p = 0.014). Four patients (16.7%) reported pain, both at T2 and T3, with a statistically significant increase between T1 and T2 (p <0.05), with moderate pain being the most observed, with no reports of severe pain. In the evaluation of the leukocyte count, it can be observed that in the period in which the patients had a greater number of oral mucositis (T2 and T3), they exhibited leukopenia, but without statistically significant differences (p> 0.05). OM had no statistically significant association with pain, associated treatment, leukopenia, comorbidities and the type of transplant, presenting for females (p = 0.015). There was no statistically significant association for pain reduction. Conclusion: The results presented showed excellent process indicators used to assess the quality of health service provision. The results of the photobiomodulation protocols demonstrated that although there is still the development of OM in these patients, there was a predominance of grade I, with less severity of

OM as well as associated pain. The female sex was more associated with the development of OM.

BANKING MEMBERS:
Presidente - 2085732 - ANA RAFAELA LUZ DE AQUINO MARTINS
Interno - 277398 - KENIO COSTA DE LIMA
Externa à Instituição - MARIA CECILIA AZEVEDO DE AGUIAR - UNIFACEX