Banca de DEFESA: MAURÍLIA RAQUEL DE SOUTO MEDEIROS

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : MAURÍLIA RAQUEL DE SOUTO MEDEIROS
DATE: 21/02/2020
TIME: 09:00
LOCAL: AUDITÓRIO DO DEPARTAMENTO DE ODONTOLOGIA
TITLE:

USE OF ANTI MICROBIAL PHOTODYNAMIC THERAPY IN THE TREATMENT OF ORAL CANDIDOSIS: CLINICAL TRIAL, CONTROLLED AND RANDOMIZED STUDY

KEY WORDS:

Candidiasis, Oral; Therapy; Photochemotherapy; Nystatin.

PAGES: 73
BIG AREA: Ciências da Saúde
AREA: Odontologia
SUMMARY:

INTRODUCTION: Oral erythematous candidiasis is a common fungal infection in users of complete dentures and patients often exhibit resistance to conventional treatment. New therapies are emerging as alternatives for its treatment, such as antimicrobial photodynamic therapy (aPDT). AIM: The present study consists of a clinical, controlled and randomized trial conducted by means of a clinical and microbiological analysis in patients diagnosed with oral erythematous candidiasis, who were divided into a control group, treated with oral nystatin suspension, and an intervention group, treated with aPDT sections. METHODS: The present study consists of a clinical, controlled and randomized trial conducted by means of a clinical and microbiological analysis in patients diagnosed with oral erythematous candidiasis, who were divided into a control group, treated with oral nystatin suspension, and an intervention group, treated with aPDT sections. Weekly, patients were reassessed as to the effectiveness of treatment through the application of a clinical index, in addition to microbiological analysis. RESULTS: Of 41 patients analyzed in our research, 5 (12,2%) gave up treatment and 4 (9,8%) were unsuccessful, and 32 (78%) were successful in their treatment. Patients were also analyzed for the degree of the lesion, and it was observed that those of the severe type had more difficulty in presenting remission, while the lesions mild and moderate, all showed regression. Although there was no statistically significant difference between the groups, the control group achieved better results than the intervention group in terms of both treatment success and microbiological analyzes. CONCLUSIONS: aPDT is a promising treatment alternative, as it presents satisfactory results, does not cause changes to oral tissues and its use does not lead to the development of resistance to treatment, so further studies with larger samples are needed to verify its effectiveness.

BANKING MEMBERS:
Interno - 2220417 - CARLOS AUGUSTO GALVAO BARBOZA
Externa à Instituição - CYNTIA HELENA PEREIRA DE CARVALHO - UFCG
Presidente - 2492713 - ERICKA JANINE DANTAS DA SILVEIRA