Banca de QUALIFICAÇÃO: HIGOR PAIVA DE MENDONÇA ALVES

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : HIGOR PAIVA DE MENDONÇA ALVES
DATE: 28/03/2025
TIME: 10:00
LOCAL: Sessão pública realizada por videoconferência: https://meet.google.com/bwf-zxyb-ygy
TITLE:

CONCENTRATION OF SELENIUM, ZINC AND IRON IN PATIENTS WITH FAMILIAL CHYLOMICRONEMIA SYNDROME (FCS)

KEY WORDS:

Hyperlipoproteinemia Type I. Minerals. Rare deseases. Insulin resistance

PAGES: 57
BIG AREA: Ciências da Saúde
AREA: Nutrição
SUMMARY:

Familial Chemicronemia Syndrome (FCS) is a rare disease characterized by the accumulation of chylomicrons in the bloodstream, leading to severe hypertriglyceridemia (>1000 mg/dL). The prevalence of this disease is approximately 1:1,000,000; however, in some areas such as Northeast Brazil, the prevalence is higher due to the founder effect. Nutritional therapy is the main therapeutic approach, consisting of a strict restriction of fat intake, with a maximum allowance of 10 to 15% of the total daily energy value or 15-20 g of total fat per day. Consequently, due to the need for severe lipid restriction in patients with FCS, it is necessary to evaluate the concentration of micronutrients and immunological markers in patients to investigate possible nutritional deficiencies and associations with their inflammatory profile. Thus, this study aims to evaluate the status of zinc, selenium and iron and inflammatory biomarkers in patients with FCS. A case-control study will be conducted, consisting of patients diagnosed with CFS treated at the Onofre Lopes University Hospital (case group), and the control group will be composed of healthy individuals matched by sex, age and BMI, in a 1:1 ratio. Data regarding socioeconomic aspects, body composition, dietary composition and biochemical evaluation will be collected. Serum levels of zinc, selenium and iron, as well as inflammatory markers will be measured. At the end of the study, it is expected to characterize a sample through the application of questionnaires, anthropometric and biochemical evaluations, and to evaluate the dietary collection of patients with CFS, considering that few studies have evaluated these parameters in this population to date. In this way, we seek to better understand the various health aspects of the population with CFS, facilitating and making decision-making for this population more accurate.

COMMITTEE MEMBERS:
Presidente - 3218336 - BRUNA ZAVARIZE REIS
Externa ao Programa - 1837354 - JULLIANE TAMARA ARAUJO DE MELO CAMPOS - nullInterna - 4659679 - SANCHA HELENA DE LIMA VALE