Banca de DEFESA: KIVIA MARIA BATISTA MARINHO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : KIVIA MARIA BATISTA MARINHO
DATE: 23/09/2024
TIME: 09:00
LOCAL: Remota via Google meet pelo Link: https://meet.google.com/qft-jxsn-fgp
TITLE:

ASSOCIATION BETWEEN INFLAMMATORY BIOMARKERS AND THE DIETARY PATTERN OF BOYS WITH DUCHENNE MUSCULAR DYSTROPHY

KEY WORDS:

Nutrition Assessment; Inflammatory Cytokines; Dietary Intake; Muscular Dystrophy

PAGES: 65
BIG AREA: Ciências da Saúde
AREA: Nutrição
SUMMARY:

Duchenne Muscular Dystrophy (DMD) is a severe progressive neuromuscular condition characterized by orthopedic, cardiac, and respiratory impairments, often leading to premature death, and currently, it has no cure. The role of inflammation in the progression of this disease has been documented in the scientific literature, with reports of high levels of inflammatory markers such as IL-1β, TNF-α, and IL-6. Considering that diet can influence systemic inflammation, this study aimed to investigate possible associations between the Empirical Dietary Inflammatory Pattern (EDIP-SP) and the inflammatory cytokines IL-1β, TNF-α, and IL-6 in the DMD population. The sample consisted of 32 boys with a mean age of 12.69 ± 5.09 years. The mean lean mass of the population was 21 ± 4.74%, and the most prevalent Vignos score was 9. The mean EDIP-SP was -0.38 ± 0.20, indicating a diet considered anti-inflammatory. However, EDIP-SP and daily energy intake showed no significant association with inflammatory biomarker concentrations in boys with DMD. These findings suggest the need for specific adaptations of assessment tools to the regional context, as they highlight the diversity of inflammatory response to dietary patterns. Although no associations were identified between inflammatory cytokines and EDIP-SP, the results provide valuable insights for the literature, considering the progressive decline in muscle tissue with age and elevated serum concentrations of inflammatory cytokines

COMMITTEE MEMBERS:
Externa ao Programa - 2578592 - KARLA DANIELLY DA SILVA RIBEIRO RODRIGUES - nullExterna ao Programa - 2549958 - LUCIA LEITE LAIS - nullExterna ao Programa - 2315640 - MARCIA MARILIA GOMES DANTAS LOPES - nullExterna à Instituição - MARINA MAINTINGUER NORDE - UNICAMP
Presidente - 4659679 - SANCHA HELENA DE LIMA VALE