Production of ceramic tapes for Biomedical applications
casting, nanomaterials, chitosan, palygorskite, neomycin, drug delivery.
In this work, studies were carried out regarding the production of ceramic tapes through the tape casting method, to obtain materials to be used in the biomedical area. Tricalcium phosphate ceramic tapes with different percentages of chitosan were produced, which served as the foundation for the subsequent works that would be produced. These were based on palygorskite clay mineral, using neomycin to study the release of this drug. The first step was to study the powders, with X-ray diffraction analysis (XRD), thermogravimetric analysis (ATG), and scanning electron microscopy (SEM-FEG). To produce the ceramic tape, the slurry was characterized through the viscosity test and then the ceramic tape was produced. These ceramic tapes were characterized through X-ray fluorescence analysis (XRF), X-ray diffraction (XRD), thermal analysis (ATG/ATD), differential scanning calorimetry (DSC), infrared absorption spectroscopy (FTIR), elemental analysis (CHN-S), scanning electron microscopy (SEM-FEG). In addition, tests of antimicrobial activity and minimum bactericidal concentration were performed, as well as calculations of absorption energy. The results obtained were thin, flexible, biodegradable, biocompatible ceramic tapes, which presented important characteristics for use in the biomedical area.