NURSING DIAGNOSIS RISK OF FRAILTY SYNDROME IN THE ELDERLY: SYSTEMATIC REVIEW OF ETIOLOGY AND RISK.
Keywords: Frailty, Frailty syndrome, Causality, Etiology, Aged, Aging, Risk factors, Vulnerability,
Nursing Diagnosis.
Objective:To identify the etiological factors related to the Nursing Diagnosis Risk of Frailty
Syndrome in the Elderly. Methods: This study will be conducted through a systematic review of
the etiology and risk factors for the Nursing Diagnosis Frailty Syndrome in the Elderly, following
the recommendations of the JBI Manual for Evidence Synthesis (Chapter 7). A prior protocol will
be developed and registered in the International Prospective Register of Systematic Reviews
(PROSPERO). The following steps will be adopted: defining the research question, identifying
relevant studies, assessing methodological quality, data extraction, and synthesis of results. The
guiding question was: "What are the etiological factors related to the Nursing Diagnosis 'Risk of
Frailty Syndrome in the Elderly'?" Literature searches will be conducted through the CAPES
Journal Portal, using the Federated Academic Community (CAFe) platform of the Federal
University of Rio Grande do Norte (UFRN), in the following databases: Scientific Electronic
Library Online (SciELO), Web of Science, ScienceDirect, CINAHL (EBSCO),
MEDLINE/PubMed (via National Library of Medicine), Cochrane Library, Scopus (Elsevier),
EMBASE, LILACS (Latin American and Caribbean Health Sciences Literature).No language or
publication year restrictions will be applied.Descriptors (MeSH/DeCS):Frailty elderly, Frailty
syndrome, Nursing Diagnosis, Etiology, Aged, Risk factor Boolean operators ("AND" and "OR")
will be used to combine terms according to the PEO (Population, Exposure, Outcome) framework.
Inclusion criteria:Studies addressing the risk of frailty syndrome in the elderly. Full-text articles
available in the databases. Exclusion criteria:Letters to the editor, editorials, protocols, books,
dissertations, theses. Studies without available full text. Studies that, after methodological
assessment, do not meet quality criteria. To minimize selection bias, article screening will be
conducted independently and blindly by two reviewers using Rayyan (Intelligent Systematic
Review) software. Methodological quality will be assessed using JBI checklists for quantitative
studies (cohort, case-control, cross-sectional, case series, and case reports). The study selection
flowchart will follow PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-
Analyses) guidelines. Data extraction will be performed using a structured instrument, and results
will be organized in comparative tables, highlighting:
Attributes, Risk factors, At-risk population, Associated conditions, Conceptual and operational
definitions.