Development of a Bulk Fill Flow composite resin with antimicrobial properties from the incorporation of plant extract
antibacterial activity; Streptococcus mutans; plant extracts; composite resin; mechanical properties.
The association of dental materials with anti-biofilm plant extracts is a reality. However, there are some factors that may make it difficult to associate plant extracts with specific dental materials, such as the color of the extract, biocompatibility and not impairing the mechanical properties of the materials. The study aims to carry out a scoping review to map the minimum inhibitory concentration of plant extracts with antimicrobial power against Streptococcus mutans and to identify the most promising plant extracts to be associated with dental materials and also to develop a Bulk Fill Flow composite resin enriched with the plant extract identified in the scoping review, perform the characterization of its antibacterial activity and mechanical and physicochemical properties. The modified Bulk Fill Flow composite resin will be evaluated for antibacterial activity against Streptococcus mutans by direct contact test and expressed by antibacterial ratio, microhardness, degree of conversion (Micro-Raman Spectroscopy), bond strength (microshear) and failure/fracture pattern. The final values will be subjected to normality tests and the parametric data will be subjected to analysis of variance (one-way ANOVA) with Tukey's post-test using GraphPad Prism 8 and Microsoft Excel 2019 software. It is expected that the most promising plant extract identified in the scoping review does not negatively affect the mechanical, physicochemical and organoleptic properties of the Bulk Fill Flow composite resin developed and that it promotes a material with antimicrobial properties.