Banca de DEFESA: ALANE DE MEDEIROS SILVA

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
DISCENTE : ALANE DE MEDEIROS SILVA
DATA : 27/08/2018
HORA: 14:00
LOCAL: Anfiteatro das Aves
TÍTULO:

CYTOARQUITETONIC AND MORFOQUANTITATIVE CHARACTERIZATION  OF THE MIDLINE AND INTRALAMINAR THALAMIC NUCLEI AND ITS GLUTAMATERGIC NEURONAL POPULATION IN ROCK CAVIES (Kerodon rupestris)

PALAVRAS-CHAVES:

Glutamate; thalamus; midline nuclei, intralaminar nuclei; stereology.

PÁGINAS: 113
GRANDE ÁREA: Ciências Humanas
ÁREA: Psicologia
RESUMO:

Glutamate (Glu) is a fundamental neurotransmitter in the processing of sensory functions, development and maintenance of cognitive processes. Among brain regions where it can be found, stands out the thalamus, a structure directly involved in both integration and modulation of sensory inputs from the periphery to the cerebral cortex. The midline/intralaminar nuclei (ML/IL) constitute a significant portion of the thalamus and have a global influence on cortical functioning. Herewith, we aim to characterize the morphology and stereology of the ML and IL nuclei of the rock cavy thalamus (Kerodon rupestris), a typical rodent of the Brazilian Northeast, as well as morphological aspects previously neglected so far on the glutamatergic neurons in LM/IL. We used 6 young adult rock cavies, whose brains were submitted to Nissl technique and immunohistochemistry against Glu. The reference volume (Vref) of ML and IL was obtained, which presented statistical difference between them, being IL bulkier than ML. The volume density (Vv) of neuronal bodies immunoreactive to Glu (IR-Glu) between ML/IL did not present statistical difference. However, in the IL nuclei, there was a higher Vv. The total volume of IR-Glu (VTot) neurons between ML/IL presented IL statistically larger than ML. The IR-Glu neuronal bodies visualized among the ML nuclei were characterized predominantly rounded and ovoid. In addition, mean cell area was statistically lower in the ML nuclei when compared to IL. As soon, similar nuclear organization in the ML/IL was revealed in the rock cavy compared to other species. On the other hand, both morphometric and stereological data have shown particular features concern to the glutamatergic neurons in the ML/IL thalamic nuclei in the rock cavy. In more general terms, differences in glutamatergic nuclear organization in the thalamus, may be related to diversity on how thalamic activity influences cortical function among species.

MEMBROS DA BANCA:
Externo à Instituição - CLARISSA LOUREIRO CAMPÊLO BEZERRA - FCM/PB
Presidente - 4363493 - EXPEDITO SILVA DO NASCIMENTO JUNIOR
Externo ao Programa - 1076490 - FERNANDO VAGNER LOBO LADD
Externo à Instituição - FRANCISCO GILBERTO OLIVEIRA - URCA
Interno - 2140860 - ROVENA CLARA GALVAO JANUARIO ENGELBERTH