Disertación/Tesis

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2024
Disertaciones
1
  • BEATRIZ APARECIDA DE SOUZA
  • Similar but not the same: intra- and interpopulational mate choice in the fiddler crab Leptuca leptodactyla (Rathbun, 1898)

  • Líder : DANIEL MARQUES DE ALMEIDA PESSOA
  • MIEMBROS DE LA BANCA :
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • FELIPE MALHEIROS GAWRYSZEWSKI
  • FELIPE PERNAMBUCO DA COSTA
  • Data: 05-abr-2024


  • Resumen Espectáculo
  • The body coloration of fiddler crabs is especially relevant in recognizing conspecifics and choosing reproductive partners. The color of fiddler crabs can vary within a population, due to factors such as age and body condition, and between populations, due to environmental differences in each location, such as different predation pressures or food composition. In the present study, we investigated the influence of body color of the fiddler crab Leptuca leptodactyla on the selection of reproductive partners. We tested the following hypotheses: 1) females prefer males with higher ultraviolet brightness and saturation and males with ultraviolet hue; 2) females prefer males from their own population over males from another population; 3) females prefer lighter males over darker males. To test these hypotheses, we performed dichotomous mate choice tests in a natural environment, which consisted of offering L. leptodactyla females the option between two males from the same population to test intrapopulation preference, and males from two populations to test interpopulation preference. We also measured the color of the males' hypertrophied chelipeds with a spectrophotometer. The analyses of color measurements were carried out using the ‘pavo’ package, in the R software (R Development Core Team). The results showed that, when given the option between two males from their own population, females preferred males with higher brightness (ultraviolet and visible) and lower green saturation. On the other hand, when confronted with local males and males from another population, females preferred local males, possibly basing this preference on information on the saturation of the hypertrophied cheliped, which differs significantly between the populations studied. Our findings provide a better understanding of the role of body color in the selection of reproductive partners in the fiddler crab L. leptodactyla. We demonstrate that natural variation in the color of the hypertrophied cheliped influences female preference for reproductive partners and that this preference can vary between populations.

2
  • JOSÉ PÉRICLES MAGALHÃES VASCONCELOS FILHO
  • PERCEPTION OF ACADEMIC PRESSURE, SLEEP PATTERNS AND MENTAL HEALTH OUTCOMES IN HIGH SCHOOL STUDENTS.

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • JOHN FONTENELE ARAUJO
  • MARIO ANDRE LEOCADIO MIGUEL
  • Data: 09-abr-2024


  • Resumen Espectáculo
  • The academic environment of high school is conducive to triggering stress in students, becoming more evident the higher the expectations of parents, the school curriculum, the fear of failure and the difficulties in making decisions. Adolescence is marked by physiological changes in the sleep-wake cycle, in which individuals start to sleep and wake up later. In contrast, schools often start classes very early in the morning, leading to daytime sleepiness, concentration difficulties, and worse cognitive processing. In this context, psychological suffering has been increasing in several countries and can have a significant impact on the development of young people. Therefore, this study aims to analyse the relationship between the perception of academic stress, sleep patterns and mental health outcomes in high school adolescents in the morning shift at private schools. The sample included 78 participants of both sexes enrolled in the morning shift in the first, second and third years of high school at two private schools in Juazeiro do Norte/CE. Participants completed the following online questionnaires: “The Health and Sleep”, The Perceptions of Academic Stress Scale, Pittsburgh Sleep Quality Index, Munich Chronotype Questionnaire, Pediatric Daytime Sleepiness Scale and Depression Anxiety and Stress Scale. The data were analysed using a Structural Equation Model after defining a final model composed of: daytime sleepiness, a latent variable representing adolescents' sleep, consisting of sleeping and waking up times during school days and free days, chronotype, social jetlag and irregularity in sleep duration, and the latent variable representing mental health formed by levels of stress, anxiety and depression. Higher levels of perception of academic stress were associated with: higher scores in the mental health construct (B=0.638; p<0.001), with a greater frequency of symptoms of stress, anxiety and depression; higher levels of daytime sleepiness (B=0.252; p=0.026); and the impact on the variables of the sleep construct (B=0.162; p=0.046), with later sleeping and waking up times on school and free days, greater trend to eveningness, higher levels of social jetlag and greater irregularities for sleep duration. The damage to mental health associated with high levels of perceived academic stress is enhanced when the sleep construct is added as an intermediary factor (B=0.731; p<0.001). We further demonstrated that the sleep construct was related to daytime sleepiness (B=0.444; p<0.001), and that higher levels of daytime sleepiness were associated with higher the scores of the mental health construct (B=0.361; p<0.001). Therefore, the perception of academic stress directly influenced, in a negative way, aspects related to adolescents' sleep, as well as mental functioning. The damage to mental health related to the perception of academic stress was enhanced when aspects related to sleep were added as intermediary factors in a single analysis. This study could contribute to expanding knowledge about the relationship between academic stress and sleep and mental health problems in adolescents, and thus help teachers and health professionals to take this discussion into their work environments.

3
  • NARITA RENATA DE MELO SEIXAS
  • EFFECT OF BLUE LIGHT THERAPY ON THE COGNITIVE, EMOTIONAL RESPONSES AND ACTIVITY-REST OF YOUNG AND AGED RODENTS

  • Líder : ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • MIEMBROS DE LA BANCA :
  • ERYCK HOLMES ALVES DA SILVA
  • FLAVIO FREITAS BARBOSA
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 10-abr-2024


  • Resumen Espectáculo
  • With increasing age, it is common to encounter behavioral changes, whether in cognitive aspects or the rhythm of activity and rest, especially in aged animals. Blue light phototherapy has been used as a method capable of providing cognitive and emotional improvements. The objective of this study was to evaluate the effect of blue light therapy on the cognitive and emotional performance of young (3 months) and aged(20 months) rats based on behavioral tests such as open field and object recognition, as well as evaluating the rhythm of activity and rest. The animals underwent a period of adaptation in the activity and rest rhythm recording box for 14 days, under a C-E cycle of 12:12 hours, followed by behavioral tests and finally, a group of treated animals underwent therapy of blue light over 14 days, under a C-C-E cycle of 6:6:12 hours. Our results show that blue light did not impair the performance of aged animals, but it also did not induce an improvement in exploratory behavior and locomotor activity in the open field, when 33 compared to young animals. Both animals did not show improvements in episodic memory in the object recognition test, but for all animals, positive effects of blue light were observed on activity and rest rhythm. In this sense, blue light therapy may be efficient and capable of causing cognitive improvements, but more studies are needed to clarify the relationship between blue light and cognitive and emotional response.

4
  • ISAURA RUTH VIEIRA DA COSTA
  • FEEDING TIME MATTERS? INFLUENCE OF TIME-RESTRICTED FEEDING ON MOTOR AND COGNITIVE ASPECTS IN A CHRONIC MODEL OF PARKINSON'S DISEASE IN RATS

  • Líder : ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • MIEMBROS DE LA BANCA :
  • JOSE RONALDO DOS SANTOS
  • PAULO LEONARDO ARAÚJO DE GÓIS MORAIS
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 11-abr-2024


  • Resumen Espectáculo
  • Parkinson's disease (PD) stands as the second most prevalent global neurodegenerative condition, affecting over 10 million individuals worldwide, with heterogeneous clinical manifestations. Animal models such as reserpine are widely used to evaluate their physiological mechanisms and possible therapeutic interventions. Time-restricted feeding (TRF), defined as the temporal adjustment of food availability without caloric restriction emerges as a potential complementary treatment in neurodegenerative disorders. Here, we evaluated the motor and cognitive effects of a time-restricted feeding intervention in a rat model of Parkinson’s disease induced by reserpine. Male Wistar rats (3-4 months) were randomly assigned to three treatment groups: time-restricted feeding for 60 days, starting 30 days before reserpine injections; time-restricted feeding for 30 days, starting with reserpine injections; and ad libitum food with reserpine injections; and two control groups: time-restricted feeding for 30 days, starting with vehicle injections and ad libitum food with vehicle injections. All animals were submitted the following tests: catalepsy test, oral movements, open field (OFT) and novel object recognition (NOR). All reserpine groups showed a progressive motor deficit, as observed in the catalepsy and vacuous chewing tests, but the TRF groups showed a delay in the onset of motor symptoms in comparison with their respective ad libitum group. Differences in performances on NOR test or OFT were not found between the reserpine groups after the intervention. Here we showed the promising effects of a time-restricted feeding diet on motor symptoms, but not cognitive symptoms caused by chronic exposure to reserpine. This is the first study to investigate TRF in a chronic model of Parkinson’s disease. Further research is needed to explore the different effects of TRF on emotional and cognitive symptoms of PD.

Tesis
1
  • STEPHANY CAMPANELLI ESMAILE
  • Physiological and psychological effects associated withnasal breathing and yoga breathing techniques
  • Líder : BRUNO LOBAO SOARES
  • MIEMBROS DE LA BANCA :
  • BRUNO LOBAO SOARES
  • DANILO FORGHIERI SANTAELLA
  • FELIPE NALON CASTRO
  • HINDIAEL AERAF BELCHIOR
  • LÍVIA CARLA DE MELO RODRIGUES
  • Data: 08-feb-2024


  • Resumen Espectáculo
  • This thesis was divided into a general introduction (in portuguese), 3 chapters (one for each article in english) and a general discussion (in portuguese). The first chapter is a systematic review published in The International Journal of Yoga that follows the PRISMA recommendations, entitled: “PRANAYAMAS AND THEIR NEUROPHYSIOLOGICAL EFFECTS”.  The aim of this review was to describe the influence of yogic breathing exercises on the human brain and mind. After filtering 1,588 articles, the final 14 articles showed that (pranayamas) in general terms promote: clinical improvement in patients with aphasia; reduced cerebral theta oscillation, increased gamma oscillation in the left medial temporal lobe, and increased inhibitory response (self-control) during a reaction time task; immediate reduction in visual and auditory reaction times and increased parasympathetic activity. The second chapter is a quasi-experimental research called PSYCHOLOGICAL EFFECTS OF A THREE-MONTHS UJJAYI PRANAYAMA TRAINING and conducted during COVID-19 pandemic. It is already under submission for publication and highlights that, before the online yoga intervention, N = 72, in the middle of the intervention, after 6 weeks, we had N = 31, and at the end (after 12 weeks) there were N = 17 women. From nine psychometric scales used in the study, we observed a reduction in mind wandering (MEWS), negative affect (PANAS-N) and perceived stress (PSS), and an enhancement in interoceptive awareness (MAIA) over the course of the intervention. Furthermore, significant positive correlations were found between MEWS, PANAS-N and PPS before and after 12 weeks of pranayama intervention. The third chapter is a RCT (randomized controlled trial) called: UJJAYI PRANAYAMA: A PHYSIOLOGICAL AND PSYCHOLOGICAL APPROACH OF A YOGIC BREATHING TRAINING. After 8 weeks of an online ujjayi intervention with university students from UFRN, the findings revealed significant improvements of the test group over the 8-week period compared to the control group for MAIA (interoceptive awareness), PANAS-P (higher pleasant moods or positive affect) and ESS-BR (lower somnolence) scores. Also, PANAS-P x MAIA had a significant and positive correlation (p = .016; r = .438). However, the control group showed better performance in the stress test (MMST) than the test group. No difference was found for delta (after minus before) of salivary cortisol, heart rate variability, Flanker test (go no-go task), spirometry, P0.1, mind wandering measures (MEWS and probe/likert scales), lung capacity and inspiratory drive (P0.1). We conclude that Ujjayi pranayama may be a useful yogic technique for reducing negative affect, perceived stress, daytime sleepiness and mind wandering while increasing interoceptive awareness and positive affect in university students and possibly in the general population. 

2
  • SARAH SOPHIA GUEDES LINHARES
  • CONSEQUENCES OF PERINATAL FLUOXETINE TREATMENT ON THE CIRCADIAN ACTIVITY-REST RHYTHM AND ON TIMING SYSTEM COMPONENTS IN MALE AND FEMALE WISTAR RATS.

  • Líder : JEFERSON DE SOUZA CAVALCANTE
  • MIEMBROS DE LA BANCA :
  • BRUNA DEL VECHIO KOIKE
  • ELAINE CRISTINA GAVIOLI
  • EZEQUIEL BATISTA DO NASCIMENTO
  • JEFERSON DE SOUZA CAVALCANTE
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 15-abr-2024


  • Resumen Espectáculo
  • High perinatal plasticity allows the brain to adapt to its environment, but it also marks a period of heightened vulnerability. The regulation of serotonin levels during development is extremely important for characteristic brain development. Changes in serotonergic signaling, both at low and high levels, appear to be harmful, leading to diverse behavioral deficits. Early exposure to antidepressants, such as SSRIs, during pregnancy or lactation implies several deleterious effects on the anatomical and functional organization in different brain circuits, including those related to the circadian rhythm. In recent years, different authors have investigated these deleterious effects and the mechanisms by which they lead to structural and functional disorganization in specific neural networks, as well as altered behavioral expression in the individual. However, there is a dearth of work at the neurochemical level on structures of the circadian timing system. In this context, this work aims to investigate whether early hyperstimulation of the serotonergic system, through perinatal exposure to an SSRI, can affect the circadian rhythm of activity and rest, especially investigating the expression of neuropeptides and clock proteins associated with the circadian rhythm at different stages of life. of the offspring (PN15, PN45 and PN90). In this study, the locomotor activity-rest rhythm and the visualization of chemical oscillatory markers of the circadian system (NPY, 5-HT, BMAL1, VIP and AVP) will be tested in two zeitgebers (ZT3 and ZT14) in exposed male and female rats. early (developmental period GD13-GD21) to fluoxetine (20 mg/kg). First, with the offspring in adulthood, we performed daily records of the locomotor activity-rest rhythm using activity sensors coupled to individual cages over four weeks, two in light-dark and two in constant-dark. Next, we will identify the expression of neurochemical markers in the suprachiasmatic nucleus, in the intergeniculate leaflet (FIG) and in the raphe nuclei in three life stages (PN15, PN45 and PN90). We hope that, at the end of all the steps, data will be generated that elucidate whether the use of SSRIs during the gestational period causes changes in the serotonergic circuitry in these mentioned regions, in such a way that it causes changes in the behavior of the circadian rhythm.

2023
Disertaciones
1
  • IGOR DE SOUZA BEZERRA
  • Let's get physical? Sexual risk behavior during the pandemic
  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • FIVIA DE ARAUJO LOPES
  • MAURO DIAS SILVA JÚNIOR
  • Data: 30-ene-2023


  • Resumen Espectáculo
  • Individual differences are unique characteristics that develop throughout an individual’s life and are formed based on genetic predisposition and lived experiences. These individual differences can modulate (inhibiting or favoring) the expression of behaviors, including sexual risk behaviors. Sexual risk behaviors are those that expose the individual to physical risck, such as involvement with sexually transmitted infections (STIs), and to social risk and vulnerability, such as early pregnancy. In our work, we present the theoretical concepts about natural selection and sexual selection, as well as the Theory of Parental Investment and Theory of Sexual Strategies; in addition, we detail the concepts of sexual risk behaviors and individual differences. Furthermore, we investigated individual differences and their relationship with risky sexual behavior, as well as variables related to individual characteristics, such as use of pre-exposure prophylaxis to HIV (PrEP) and non-mongamous tendency. Data collect was online, with 293 participants, who answered instruments of personality traits, impulsiveness, sexual sensation seeking, life history strategies and sociosexual orientation, and also a sociodemographic questionnaire with information on sexual risk behaviors. From the sociodemographic data related to sexual risk behaviors, the Sexual Risk Score was created, which represents the level of exposure to sexual risks of each participant, containing information on the number of sexual partners, condom use, substance use during the sexual act, use of PrEP etc. This score was used for data analysis through correlation tests. It was found that sex, sexual orientation and socioeconomic status did not correlate with sexual risks. Extroversion, narcissism and psychopathy personality traits, as well as sexual sensation seeking and unrestricted sociosexual orientation were positively correlated with sexual risks. In turn, neither impulsivity nor the life history strategy correlated with sexual risks. This work brings information about how sexual risk behaviors can have their expression increased due to individual differences, which may favor the increase in the number of individuals affected by sexually transmitted infections (STIs). This knowledge brings an important contribution to combating the spread of STIs, and can be used to prevent new infections from occurring.

2
  • ANNE KELLY COSTA MORAIS
  • COOPERATION POST COLLABORATIVE ACTIVITY AND INFLUENCE OF GESTURES IN VISUAL SPATIAL ACTIVITIES
  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • MAYARA WENICE ALVES DE MEDEIROS
  • RACHEL COÊLHO RIPARDO TEIXEIRA
  • Data: 09-feb-2023


  • Resumen Espectáculo
  • Cooperation is a behavior that benefits the other and is characterized by a decrease in the immediate fitness of those who practice it. Several hypotheses were created to explain the possible advantages and, therefore, the maintenance, in evolutionary terms of this behavior: the interdependence hypotheses, kin selection, direct and indirect reciprocity and cultural evolution. The expression of cooperation may vary according to sociodemographic characteristics, such as social class and gender, or even according to the presence of a collaborative activity before the division of resources. In addition to investigating factors associated with cooperation in children, the present work also proposes to understand the role of gestures in establishing visuospatial information in collaborative interactions. According to the Information Packaging Hypothesis, when there is a greater demand for conceptualization during a cognitive activity, the tendency is for more gestures to occur. To test this hypothesis in a collaborative context, videos of children performing a post-collaborative activity cooperation task were analyzed. The activity involved visuospatial processes and the gestures that occur after the two-part explanation of the task were analyzed. Regarding the earning and sharing of resources, only age was a relevant factor to influence them. Furthermore, there were no more gestures when the task showed greater cognitive demand.

3
  • LUCAS EMANUEL FERREIRA
  • The tug of war between pathogen avoidance and sexual behavior in a setting pandemic
  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • ANTHONIETA LOOMAN MAFRA
  • Data: 10-feb-2023


  • Resumen Espectáculo
  • Since the immune defense against pathogens is expensive and merely reactive, human anti-pathogen defense is also characterized by proactive behavioral mechanisms that inhibit contact with pathogens. This behavioral immune system (BIS) comprises psychological processes that reduce the risk of contagion by responding to environmental cues through the activation of aversive behaviors. 

4
  • SIMONE PERUZZO
  • The coming and go of people: group cohesion in capuchin monkeys (Sapajus flavius)

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • TIAGO FALOTICO
  • ARRILTON ARAUJO DE SOUZA
  • RENATA GONCALVES FERREIRA
  • Data: 14-abr-2023


  • Resumen Espectáculo
  • The intensity of intragroup food competition and the perception of risk are forces that, in interaction, generate and shape the sociality of primates, being important predictors of group size, cohesion and interindividual proximity. This study analyzed the spatial cohesion of a group of capuchin monkeys (Sapajus flavius) in an Atlantic Forest fragment in a secondary stage of regeneration on the border between the states of Paraíba and Pernambuco. We were in contact with the group for 352 hours and obtained 591 scans that contained the spatial position of each individual. We tested five hypotheses with the area of the least convex polygon weighted by the size of the group, the number of individuals in the group, the inter-individual distance and the distance to the centroid as our response variables, and the productivity of the area, proximity to edge, tree stratum, period of the day and sex/age of the individuals as predictive variables of the models. Greater fruit availability was related to smaller groups, less cohesion and greater distance from the centroid, while greater insect productivity explained greater cohesion and larger groups. The variables related to the perception of risk (ground, proximity to the edge, risky behaviors) explained the greater cohesion, larger groups, greater inter-individual proximity and in relation to the centroid. Juveniles were closer to the centroid and males were more peripheral, when juveniles were on the ground they approached females and males approached subadults. The pattern found indicates an indirect competition system characterized by greater distance when there was greater availability of fruits, spatial formation of the group (centroid-periphery) and the differential use of tree strata. While larger, more cohesive groups allowed the group to access substitute resources in areas of greater risk, during periods of reduced food supply.

5
  • MARIA MIXSSAEYDE SILVA DE MOURA
  • Effects of environmental enrichment with classical music on the behavior of zebrafish subject to unpredictable chronic stress.

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • DENIS BROOCK ROSEMBERG
  • PRISCILA FERNANDES SILVA
  • Data: 28-abr-2023


  • Resumen Espectáculo
  • All living beings, regardless of their species or environment in which they are inserted, face stressful situations, predictable or not: food restriction, risk of predation, protection of offspring and other environmental conditions. As in many other species, exposure to something new can evoke anxiety responses in zebrafish, similar to what happens in rodents, for example, when placed in a new environment to observe their exploratory activity it presents a typical fear and anxiety behaviors in the species, such as freezing and reduced time at upper zone of the aquarium until the individual assesses whether it is safe to explore the environment. It is already known which exposure to chronic stress can contribute to development of anxiety and depression.

    Many practices, mainly that use of controlled medication, have been used in order to minimize the negative effects of stress and psychiatric disorders. However, despite the benefits of using these drugs in therapeutic treatment, side effects deserve due attention, such as memory disorders, decreased psychomotor activity, mental confusion, social problems and abuse or dependence. It is known that prolonged consumption of anxiolytics can lead to tolerance, withdrawal and dependence. Based on that, some no-drugs alternative therapies are been adhered like auditory enrichment with classical music that improves welfare and reduces negative effects of stressful conditions. The auditory stimuli can affect physiology and behavior. It is already known that exposure to music, especially classical music, is beneficial in humans in reducing anxiety, improving sleep quality, reducing pain perception and is effective in environmental enrichment in several species. Therefore, music can be used as an alternative therapy in stressful situations. The zebrafish (Danio rerio) is a promising model to study human disorders in behavior, physiological responses and hearing research. To analyze the effects of classical music in stress, anxiety-like and depression-like behavior, we exposed adult zebrafish twice a day for 15 days of Vivaldi’s collection and tested in the open field, homebase formation and sociability test, to evaluate how UCS protocol (unpredictable chronic stress protocol) and music exposure can affect the exploration in the environment.

6
  • JOSÉ EDUARDO DA SILVA FILHO
  • EFFECT OF GENDER, AGE AND ECONOMIC POWER ON AGE PREFERENCE OF PARTNERS

  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • FIVIA DE ARAUJO LOPES
  • WALLISEN TADASHI HATTORI
  • Data: 28-abr-2023


  • Resumen Espectáculo
  • Age is important in choosing a mating partner, as it is associated with many attributes that contribute to an individual's mating value. This study investigated how sex, age, and economic power can influence patterns of age preference for an idealized partner and partner choice. Heterosexual individuals of both sexes participated in the study, ranging in age from 12 to 32 years and belonging to various economic power classes. This research presents a quasi-experimental design with a sample of 2504 participants (1560 women) for preference analysis and a sub-sample of 1443 participants (931 women) for choice analysis. All participants completed questionnaires providing sociodemographic data, indicating the minimum, maximum, and ideal age for an idealized partner, and responded to an instrument that assessed their economic power. Those involved in romantic relationships also indicated their partners' ages. General linear models were applied to investigate the effect of sex (female and male), age range (12-17 years | Adolescents, 18-23 years | Young Adults, and 24-32 years | Adults), and economic power (A-B1 | High, B2-C1 | Intermediate, and C2-DE | Low) on the difference between the indicated ages and the participants' ages. In general, it was observed that men prefer partners with younger minimum, maximum, and ideal ages when compared to women. Men prefer increasingly younger partners (minimum and ideal age) as their age increases, and adolescent males idealize partners older than themselves. Women prefer partners older than themselves (3.41 years) and with a minimum age close to their own, but adult women accept younger partners (minimum and maximum age). Preferences were manifested in choices, as women have older partners when compared to men. Economic power influenced both preferences and choices. Adult women with lower economic power accept partners with a younger minimum age, while adult men with lower economic power accept partners with a higher minimum age, a finding that may represent a reduction in the level of demand due to lower mating value originating from low economic power. It was also found that adolescents with higher economic power seek partners with a higher maximum age, indicating that having high economic power would make adolescents more demanding in seeking partners. Finally, the effect of economic power on choices was observed, as adult women with lower economic power formed pairs with younger men. It was concluded that sex, age, and economic power influence preferences and choices and that economic power can influence mating value by affecting demand levels in seeking partners. These findings expand the understanding of the importance of socioeconomic status in relationships.

7
  • ROBERTA BARBOSA COSTA LIMA
  • From the Board to Life: Transferring Skills Trained in Chess to Other Contexts

  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • JESSICA JANINE DE OLIVEIRA
  • ULYSSES PAULINO DE ALBUQUERQUE
  • Data: 05-may-2023


  • Resumen Espectáculo
  • This study aimed to investigate the effect of chess practice on the adoption of the life history strategy, on levels of focused attention, self-efficacy, self-control, procrastination and resilience in adults and adolescents. To achieve this purpose, instruments were applied to assess the aforementioned variables in a sample of 225 participants, composed of adolescents (14 to 17 years old) and adults (18 to 57 years old), both age groups divided into subgroups of chess practitioners and nonpractitioners. The results of the analyzes indicated that no differences were observed between groups and genders for a life history strategy variable. For the focused attention variable, it was observed that only the Adult Chess Players group had higher focused attention than the other groups. With regard to the procrastination variable, it was observed that the Adult Chess Players group had a lower procrastination score than adolescents chess players and non-chess players, but it was observed a similar value comparing with adults who are not chess players. We also observe that Adult Chess Players showed higher resilience and self-efficacy than the other groups. The research and findings in the present study shed light on the importance of understanding how behaviors not directly linked to contexts of academic and professional conduct (such as games, sports and leisure time) can affect our performance, our choices and our cognitive functions.

8
  • DAVI ANDRADE BARRETO
  • Understanding domestic violence by multiple partners in a Brazilian sample
  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • HELLEN VIVIANNI VELOSO CORRÊA
  • ROSANA SUEMI TOKUMARU
  • Data: 30-may-2023


  • Resumen Espectáculo
  • Intimate partner violence affects victims and society as a whole, and it can affect both men and women. One of the issues little investigated in the literature on domestic violence from an evolutionary perspective is revictimization by multiple partners, especially in the Brazilian context. According to this perspective, it is expected that the choice of partners favors the survival and reproduction of the offspring, elements that are harmed in an abusive relationship, even more so when they are recurrent. This research had a cross-sectional and exploratory character with the objective of identifying which individual characteristics configure groups with this type of revictimization in adults of both sexes. An online questionnaire was applied that contained: questions about sociodemographic data, experience of intimate partner violence, the Rosenberg Self-Esteem Scale, the Experience in Close Relationship Scale - Reduced and the Childhood Trauma Questionnaire. Groups that experienced violence from multiple partners were found to have lower self-esteem, higher scores on attachment-related anxiety, higher scores on attachment-related avoidance, and more experiences of childhood violence than groups that experienced one or no domestic violence. These findings favor the perspective that revictimization is a by-product of adaptive functions of the human mind, related to the self-perception of value in the mating market and the relationship model learned with caregivers.

9
  • IGO PADILHA DE SOUSA
  • ORIGENS DO DESENVOLVIMENTO DO ESTADO DESAMPARADO EM ZEBRAFISH (Danio rerio): INFLUÊNCIA DO ESTRESSE PRECOCE E DA EXPOSIÇÃO FETAL AO ALCOOL

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • ELAINE CRISTINA GAVIOLI
  • AMAURI GOUVEIA JR
  • Data: 02-jun-2023


  • Resumen Espectáculo
  • Diversos traumas nos anos iniciais da vida podem causar danos no futuro, alterando o comportamento e a fisiologia de indivíduos na fase adulta. As origens do desenvolvimento da saúde e da doença (DOHAD, do inglês Developmental Origins of Health and Disease) liga a ocorrência de distúrbios precoces, no início da ontogenia, ao desenvolvimento de desordens fisiológicas, comportamentais e psicológicas futuras. Nesta perspectiva, esse trabalho se dedica ao estudo das desordens do espectro alcoólico fetal (FASD, do inglês Fetal Alcohol Spectrum Disorders) que podem causar efeitos ao longo do desenvolvimento e podem gerar déficits sociais, cognitivos e comportamentais. No entanto, não é apenas a exposição precoce ao álcool que pode causar distúrbios ao longo do desenvolvimento. Diversos estressores presentes no meio ambiente são considerados fatores de risco, esses estressores são conceituados como circunstancias que ameaçam a integridade física ou o bem-estar psicológico, e podem trazer diversos malefícios à saúde, principalmente quando o estresse se torna crônico. Neste sentido, o presente trabalho tem o objetivo de examinar a influência do estresse crônico precoce e da exposição fetal ao álcool no comportamento de peixes zebra submetidos ao estado de desamparo inato e aprendido. O estado desamparado em animais é análogo à depressão em humanos: indivíduos que se encontram nesse estado têm dificuldades na resposta de alerta e na capacidade de aprendizagem como consequência da exposição previa a estímulos aversivos incontroláveis. Para que os objetivos dessa pesquisam sejam alcançados, serão aplicados dois estressores em estágios iniciais do desenvolvimento do zebrafish: exposição ao álcool e ao estresse crônico. Esses animais passarão por testes de testes de imobilização (reposta reflexa inata) e condicionamento aversivo (choque elétrico como estimulo não condicionado). Considerando que a DOHAD pode implicar no desenvolvimento de depressão e desamparo, ou contribuir para o desenvolvimento destas condições, é importante o aprofundamento nesse tema, pois tratamentos eficazes dependem do conhecimento das possíveis causas da depressão e do estado desamparado. Assim, este estudo trará novas informações sobre as respostas inatas e aprendidas, que são potencialmente relevantes para a busca por drogas para o tratamento da condição de desamparo e depressão. Além disso, pretende-se validar o zebrafish como modelo experimental para estados de desamparo.

10
  • HECTOR DAVID QUINONES VARGAS
  •  Pharmacological effects of the main active compounds of ayahuasca on anxious type behaviors and memory in zebrafish (Danio rerio)

  • Líder : BRUNO LOBAO SOARES
  • MIEMBROS DE LA BANCA :
  • BRUNO LOBAO SOARES
  • FERNANDA PALHANO XAVIER DE FONTES
  • ROBSON SAVOLDI
  • Data: 28-jun-2023


  • Resumen Espectáculo
  • Anxiety disorders are among the most prevalent mental health ailments affecting millions of people around the world. Despite substantial progress in the development of new drugs to treat anxiety disorders, current treatments have limited efficacy. Thus, an enormous effort has been devoted to the search for alternative pharmacological treatments. A class of drugs with a pivotal serotonergic agonist action known as psychedelics have shown to be a promising treatment alternative for anxiety disorders, and for the cognitive deficits exhibited by critically depressed patients with co-morbid anxiety. One particular psychedelic, known as Ayahuasca, that is made from the combined infusion of Banisteriopsis caapi stem rich in monoamine oxidase inhibitors (MAOi) such as Harmine and other Beta-Carbolines, and Psychotria viridis leaves, rich in N, N-dimethyltryptamine (DMT), has particularly stood out as a new treatment for depression and anxiety disorders. For the purposes of this study, we evaluated the effects of increasing concentrations of the main active compounds found in Ayahuasca on the behavioral performance of zebrafish (Danio rerio). Adult zebrafish were exposed to 3 different concentrations of: DMT, Harmine, and both alkaloids combined. To determine the therapeutic effects of the alkaloids on memory, and anxiety, behavioral parameters of the zebrafish were assessed with a Novel Tank Diving task and a Conditioned Place Aversion (CPA) task in which place-conditioned aversive memory of the zebrafish was assessed, alongside locomotive behavioral parameters indicative of anxious type behaviors. The behavioral variables analyzed for this study were average swimming speed, maximum speed, total distance covered, freezing, number of entries in the checkered pattern of the CPA tank associated with an aversive stimulus (alarm substance), and time spent on each side of the CPA tank. The results of this study showed that chronic treatment (10 exposures, with a 3-day interval) with increasing concentrations of the main active compounds of ayahuasca (either independently administered or together) exerted pharmacological anxiolytic effects in conditioned place aversion and the novel tank task. For parameters related to anxiety in both tasks, high concentrations of harmine, and DMT in association with Harmine were effective while DMT in all concentrations was only effective in the CPA task. In regards to the effects of these compounds on place-conditioned aversion, we observed that only the low DMT concentration of 0.0038 mg/L significantly made fish spend more time in the side of the CPA tank that was not associated with an aversive stimulus (alarm substance). With this low concentration, animals also exhibited an anxiolytic effect on the CPA task aside from the effect observed on the time that was spent on each side of the CPA tank. These results suggest that low concentrations of DMT might have an effect on the time spent on each side of a CPA tank during testing, while any concentration of DMT and higher concentrations of harmine have anxiolytic properties.

11
  • NATSUMI HAMADA FEARNSIDE
  • The hand that rocks the cradle: Infant and juvenile care of wild blond capuchin monkeys (Sapajus flavius)
  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • GISELA BARBOSA SOBRAL DE OLIVEIRA
  • RENATA GONCALVES FERREIRA
  • SARAH ELIZABETH TURNER
  • Data: 15-jul-2023


  • Resumen Espectáculo
  • In social animals, immaturity represents an important phase in life history in which physical, motor and social development mature. Immaturity is a crucial phase to understand for effective population management. The blond capuchin monkey (Sapajus flavius) is an endangered species endemic to the northeast of Brazil and is restricted to a few fragments of Atlantic Forest and Caatinga. Though there is a growing body of knowledge about the ecology of this species, descriptions of specific aspects of social behavior, particularly parental care, are scarce and are usually either secondary to the main study or are anecdotal. This study intends to document the forms of infant and juvenile care in a group of free-ranging S. flavius inhabiting an Atlantic Forest fragment in northeast Brazil. Data were collected from February to September (excluding August), 2021, resulting in 294.4 contact hours with the group, totaling 112.6 hours of direct observation (n=1105 focal samples). Behavior was collected using the focal animal method, with scans every minute to note the number of neighbors at 1 and 5 m, and which strata the animal was on. We analyzed whether ecological factors like fruit productivity, season, forest strata, and distance to forest edge influenced the form of care given to immatures, and how care changes according to different age/sex classes. In terms of direct care, a female literally carries most of the burden, being the ones transporting the immature 93% of the time, while older juveniles and adult males carried youngsters far less (5% and 2%, respectively) and most often sharing food. They are also the class that most grooms and shares food with immatures. Females with infants are the most attractive group member, as they are the most groomed and most often followed class and are seen more than expected by chance as neighbors at 1 and 5 m from almost every other age/sex class. Young immatures receive significantly more direct care than older juveniles. Males provide indirect care mostly in the form of producing scraps for scavenging, tolerating juveniles scrounging on their food, and maintaining proximity to females carrying infants and young juveniles, being seen near young juveniles and females with infants more than expected by chance (1m: χ²=2167.9, p<0.001, R2adj=12.5 and 7, respectively 20.6; 5 m: χ²=2301.2, p<0.001, R2adj=20.6 and 10.8, respectively), which could represent a form of protection from predators. The upper canopy does not seem to be perceived as more dangerous than the middle substrates, as grooming and nursing rates were high in this stratum, as opposed to the ground, where these behaviors were seen far less or not at all. Fruit productivity was slightly positively correlated with nursing frequency, but not with grooming frequency. Overall, our results corroborate with what has been inferred for this species in terms of direct care for immatures and support the fact that there is extended care up to the first year of the immature. Additionally, data on proximity indicate that males may play an important role in escorting females with infants throughout the day.

12
  • HANNA CARLA GURGEL ARRUDA
  • CLASSIFICATION OF EEG SIGNALS: A COMPUTER VISION APPROACH WITH CONVOLUTIONAL NEURAL NETWORKS FOR PREDICTING EPILEPTIC SEIZURES

  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • JOHN FONTENELE ARAUJO
  • RENAN CIPRIANO MOIOLI
  • LUCAS GALDINO BANDEIRA DOS SANTOS
  • Data: 18-oct-2023


  • Resumen Espectáculo
  • Electroencephalography (EEG) is a non-invasive technique for recording and monitoring brain electrical activity. The EEG signals obtained provide valuable information about cognitive processes, mental states, and neurological conditions such as epilepsy. EEG plays a fundamental role as a diagnostic tool in medicine and extends to various fields, including neuroscience and biomedical engineering. One crucial aspect of EEG study is related to the detection and prediction of epileptic seizures. According to the World Health Organization (WHO), epilepsy affects approximately 50 million people worldwide. The traditional diagnosis of epilepsy involves visual analysis, conducted by a neurologist, of hours of EEG recordings to identify electroencephalographic patterns associated with seizures. However, this process can be costly and is subject to human errors. Faced with this challenge, researchers have been dedicated to seeking alternatives that can reduce analysis time and thus assist in more efficient diagnosis. As an alternative to this scenario, the application of artificial intelligence (AI) techniques can aid in the diagnostic process. The objective of our work is to propose a methodology for EEG signal classification to detect epileptic seizures. We used the open-source EEG dataset from Boston Children's Hospital, consisting of recordings of 198 seizures in 24 patients aged between 1.5 and 22 years. The data were pre-processed to remove noise and artifacts using the MNE Python library, specifically designed for neurophysiological analyses. The data were transformed into images for input into a Convolutional Neural Network (CNN). We implemented a 19-layer CNN in the Python language using the free Google Colaboratory platform. We selected 6 patients for model training using cross-validation and used the remaining 18 patients for individual tests to assess the model's generalization capability. We conducted four training sessions using different techniques to address data imbalance. Due to class imbalance that biases accuracy metrics, we considered Recall for class 1 as the most important metric for model selection for test data application. We achieved an average Recall for class 1 of 73% with unbalanced data and 83% with balanced data in the training set. In the test set, the averages were 38% and 74%, respectively. Computational resources were a limiting factor, influencing the size of the training set and the variability of patterns to be learned by the network. Nevertheless, we consider that our classification achieved good performance, especially given the challenge of dealing with extreme class imbalance. 

Tesis
1
  • ANA LUISA PIRES MOREIRA
  • SUNSCREENS:PROTECTION OR THREAT? EFFECTS OF OXYBENZONE EXPOSURE IN ZEBRAFISH (Danio rerio)
  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • GISELE GIANNOCCO
  • BEMJAMIN GEFFROY
  • ANA CAROLINA LUCHIARI
  • EDUARDO BESSA PEREIRA DA SILVA
  • SILVIA REGINA BATISTUZZO DE MEDEIROS
  • Data: 13-feb-2023


  • Resumen Espectáculo
  • Benzophenone-3 (BP-3) has been the most widely used ultraviolet filter (UV filter) in sunscreens. Its broad use by industries results in continuous discharge into aquatic environments, leading aquatic biota and humans to continuous exposure. The consequences of BP-3 exposure on the physiology of animals have been investigated, including their neurotoxic effects and as an endocrine disruptor. However, little is known about its consequences in longterm developmental and behavioral endpoints. This study aimed to investigate the long-term effects of BP-3 exposure on behavioral and cognitive responses in zebrafish and evaluate biomarkers of oxidative stress and neurotoxicity. For this, we exposed zebrafish embryos (6-96 hpf exposure) and adults (15 days exposure) to BP-3 to evaluate the pollutant consequences. We analyzed anxiety-like behavior, social preference, aggressiveness, learning, and memory as behavioral endpoints, as well as reactive oxygen species (ROS) production, the enzymatic activity of the antioxidant defenses system, and neurotoxic biomarkers (GST, CAT and AChE), and expression of genes related to the antioxidant defenses. In general, animals exposed to BP3 showed increased anxiety-like behavior and reduced social preference. Cognition, in terms of learning and memory, was damaged by BP-3 exposure. The increase in ROS was accompanied by an increase in sod2 and cat gene expression and an increase in GST activity and decreased CAT activity. The biochemical changes caused by BP-3 exposure in larvae were maintained in adulthood. The behavioral and cognitive alterations associated with the biochemical responses found are critical for the survival of several species, represented here by the animal and translational zebrafish model. The continued exposure to personal care products that contain high concentrations of UV filters, whether based on oxybenzone or another organic filter, has harmful physiological effects and should be avoided. We must consider new types of UV filters and change our habits for a safer life and environment.

2
  • ERYCK HOLMES ALVES DA SILVA
  • Light therapy effects on the circadian rhythm of activity-rest and on the neurochemical expression of the suprachiasmatic nucleus of aging rats
  • Líder : ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • FELIPE PORTO FIUZA
  • GISELE AKEMI ODA
  • MARIA PAZ LOAYZA HIDALGO
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 15-feb-2023


  • Resumen Espectáculo
  • The effects of aging on circadian rhythms have implications ranging from complex cognitive performance to simple physiological functions. These changes include alterations in the pattern of rhythmic expression, such as a wide fragmentation of the rest-activity rhythm, decrease in amplitude and difficulty in resynchronization regulated by the suprachiasmatic nucleus (SCN). The study of the biological effects of light has received a great current interest, due, among other aspects, to its positive response in psychiatric disorders in humans, such as seasonal depression. However, data with methodological standards on the effects of light are still conflicting and scarce. With that in mind, light therapy can be used to stimulate the SCN to improve its stability in an ontogenetic phase in which various circadian dysregulations occur, possibly due to damage to this pacemaker. The objective of this work is to evaluate the effect of therapy with blue light on the functional aspects of the SCN of aged rats, through the evaluation of the rest-activity rhythm, as well as on possible neuronal changes, with evaluation of NeuN-IR, and neurochemistry, through BMAL1-IR. For this, 43 male Wistar rats (650-690g) aged sixteen months were used. The animals underwent continuous recording of locomotor activity and were exposed for 6 hours to low-intensity blue light (150 lux; peak at 470-490 nm) during the first half of the light phase of the 12:12 h light-dark cycle for 14 days. Some animals were perfused at this stage in ZT6 or ZT12. At the end of blue light therapy, the remaining animals returned to baseline photic conditions for another 14 days, being perfused at the end. After exposure to low-intensity blue light, the animals showed changes in SCN locomotor and neurochemical rhythmicity patterns. It was observed that blue light seems to have a positive effect, promoting an increase in rhythmic robustness, favoring greater consolidation in the resting phase, increasing the circadian function index, in addition to increasing the number of BMAL1-positive cells in the SCN. We believe that our study will serve as a basis for understanding the neurobiological mechanisms of using blue photic exposure as an effective method to minimize circadian disorders of the aged timing system. 

3
  • CAROLINE PERIPOLLI DOS SANTOS
  • Individual differences and psychoactive substances: alcohol and caffeine effects on zebrafish behavior (Danio rerio)

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • FIVIA DE ARAUJO LOPES
  • PRISCILA FERNANDES SILVA
  • STEFANI ALTENHOFEN
  • VANESSA DE PAULA SOARES RACHETTI
  • Data: 23-mar-2023


  • Resumen Espectáculo
  • Individuals have different behavioral traits that make up their personalities. Traits are considered characteristics that both have a genetic basis and are shaped by experiences throughout life, and guide the way individuals behave in different situations and environmental contexts experienced. The wide behavioral variability in a population is important for species maintenance and individual survival. These characteristics may also be related to risk behavior and influence the consumption, effects, and sensitivity of individuals to psychoactive substances. Among them, alcohol and caffeine seem to be the most consumed worldwide. Alcohol is the licit drug responsible for numerous diseases and accidents in human beings, while caffeine, despite not having such serious effects, can also be harmful if consumed in large quantities. Thus, the objective of this thesis was to evaluate the response of behavioral profiles related to one of the personality traits, the bold-shy profile, under the influence of alcohol and caffeine in zebrafish. In the first chapter, we assess the differences between the profiles of a zebrafish population, to determine the risk-taking and exploration behaviors that determine the two extremes of the bold-shy continuum. Then, we tested the extreme profiles in two different contexts, an affiliative context (social group) and an aversive context (presence of a predator), and under the effect of chronic and acute treatments with alcohol (chapter 2) and caffeine (chapter 3). Our results show that bold and shy profiles show differences in risk-taking, bold individuals are more prone to risk than shy ones, and in exploratory response, bold individuals are more exploitative than shy ones. Furthermore, the profiles respond differently to drug concentrations and analyzed contexts, with differences in drug sensitivity, which makes bold individuals more sociable in some situations and shy individuals less risk-averse in others. Our data show that there is a difference in responsiveness between bold and shy, corroborating studies that relate personality to the effects of psychoactive substances. We hope these results will help advance further research on the effects and treatments for substance abuse and its consequences. Finally, we reinforce the use of zebrafish as an adequate and reliable tool for translational studies related to psychotropic drugs

4
  • NELYANE NAYARA MARTINS DE SANTANA
  • Morfo-quantitative and neurochemical analysis of subcortical visual system in aged marmoset (Callithrix jacchus)

  • Líder : ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • MIEMBROS DE LA BANCA :
  • FERNANDO VAGNER LOBO LADD
  • JEFERSON DE SOUZA CAVALCANTE
  • JOSÉ RODOLFO LOPES DE PAIVA CAVALCANTI
  • PAULO LEONARDO ARAÚJO DE GÓIS MORAIS
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 25-abr-2023


  • Resumen Espectáculo
  • The Dorsal Lateral Geniculate Nucleus (DLG) and the Superior Colliculus (SC) are subcortical structures that comprise image-forming system. Functionally, DLG is considered a first-order thalamic nucleus in the processing of visual information, with relay properties and modulating the retinal inputs to the visual cortex. The CS participates in transferring incoming retinal inputs to other subcortical visual structures and sensorimotor transformations to drive movements of orientation and attention of the eyes and head. These two subcortical nuclei constitute the two main visual pathways in mammals, contributing to the interpretation and subsequent formulation of adequate visual responses by the visual cortex. However, this visual processing is changed by aging, leading progressive functional deficits. Despite these, few studies discuss possible morphological and neuropeptidergic changes that might be directly related to the decline in visual function during aging. In this context, the present study aims to describe quantitatively morphological and neurochemical parameters in the DLG and CS in response to the aging process. Female and male marmosets (Callithrix jacchus) were divided into two age groups: adults (36-50 months old) and aged (119-140 months old) and perfused with formalin (10%). Then, the brains were sectioned (30µm) and submitted to Nissl method and immunohistochemistry for neuronal nuclear protein (NeuN) and protein glial fibrillary acidic protein (GFAP). Through the morphometric cell counting, optical density (OD) and designbased stereological probes, such as Cavalieri estimator, the neuronal number and immunoexpression of astrocytic GFAP, as well as the total and layers volume of DLG and SC were assessed, respectively. Based on these techniques, our results evidence a total and layers volumetric increase of the GLD, in addition to an overall stability in the volume and neuronal number of the superficial layers of SC with aging. A age-related decrease of GFAP immunoexpression was found in the DLG and SCv. Our findings suggest a region-dependent variation in volumetric aspect during aging, perhaps due structural plastic events in response to inflammation and compensatory mechanisms in the cellular and subcellular componentes of 16 this visual structures. Moreover, the SCv appears to be less vulnerable to aging effects regarding of volume and neuronal number. Neuropeptidergic data suggest that declined GFAP expression may reflects a astrocytic atrophy. Hence, we provide an update the current state of knowledge of aging effects in the visual system and an important foundation for future works in terms of visual perception over course of aging, particularly in its morphological-quantitative and neurochemical parameters.

5
  • JÚLIO CÉSAR DE OLIVEIRA LEAL
  • Exposure to an abnormal light condition during the lactation phase: effects on behavioral aspects and protein expression in adult Wistar rats.

  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • JOHN FONTENELE ARAUJO
  • MARIO ANDRE LEOCADIO MIGUEL
  • HORACIO DE LA IGLESIA
  • BRUNA DEL VECHIO KOIKE
  • GISELE AKEMI ODA
  • Data: 27-abr-2023


  • Resumen Espectáculo
  • In adult rats, exposure to constant light condition (LL) leads to uncoupling of the circadian multiple oscillators on the suprachiasmatic nucleus (SCN) and it can produce an arrhythmic pattern on locomotor activity, cognitive and emotional impairments. However, when rats are kept in LL on lactation phase, they develop a circadian rhythm which is maintained for many days after weaning. The aim of this study is to investigate the effect of LL during lactation in cognitive performance, anxiety-like and depressive-like behaviors in adult rats in LL or in a sub-sample of adult rats in LL that kept a long-term circadian rhythm. Male Wistar rats were submitted to LL on lactation phase, from postnatal day 1 (P1) to P22. On weaning, they were transferred to 12:12 light and dark cycle (LD), and on P61, they returned to LL (LL-LD-LL group; n = 8). As a control, a group were maintained in LD 12:12 for the entire experiment (LD-LD-LD; n = 7). ~P107, rats were submitted to an open field test (anxiety-like task), novel object recognition, object-in-place and passive avoidance tests (memory tasks) and sucrose preference test (anhedonia test). Food consumption and body mass were register weekly from the weaning. Finally, rats were euthanized one week after the last behavioral task in order to quantify the expression of c-Fos in the SCN, hippocampus, amygdala and pre-frontal cortex. Our preliminary results showed that 4 rats from LL-LD-LL group kept a long-term rhythm of locomotor activity and 4 rats did not. Moreover, LL-LD-LL showed a higher latency to start the rearing behavior in the open field, and did not show both object recognition and object and location association memory. Finally, LL-LD-LL show a weekly food consumption and body mass similar to LD-LD-LD group. The results for the sub-sample LL-LD-LL group, that kept a long-term circadian rhythm, are the same. Together, these preliminary results indicates that exposure to LL on lactation do not prevents impairments on object and spatial recognition, and this effect is independent of the maintain of a long-term circadian rhythm. More experiments with adaptations on the length of the reexposed to LL are necessary in order to get more conclusive results.

6
  • LUCAS GALDINO BANDEIRA DOS SANTOS
  • Characterization of the Functional Interhemispheric Connectivity using EEG and a Bistable Visual Illusion of Movement


  • Líder : KERSTIN ERIKA SCHMIDT
  • MIEMBROS DE LA BANCA :
  • KERSTIN ERIKA SCHMIDT
  • JOHN FONTENELE ARAUJO
  • CLAUDIO MARCOS TEIXEIRA DE QUEIROZ
  • BRUSS REBOUÇAS COELHO LIMA
  • WILFREDO BLANCO FIGUEROLA
  • Data: 19-jun-2023


  • Resumen Espectáculo
  • Visual illusions can be defined as a dissociation of the physical properties of a visual stimulus that generates an altered or bistable perception. In the field of illusions, the Motion Quartet (MQT) is a well-studied paradigm characterized by generating illusory motion in cardinal directions: vertical and horizontal. However, there is still no evidence regarding the display of this stimulus in different regions of the visual field or after the substitution of its constituent elements by Gabor patches during electroencephalography (EEG) recording. Thus, this project aims to characterize the inter- and intra-hemispheric connectivity of the visual cortex in healthy individuals. At the moment, 32 healthy volunteers have participated in the study. All volunteers went through the following stages: pre-evaluation, screening, and EEG experiment during the performance of the MQT task. After recording, inter-hemispheric connectivity was evaluated using computational metrics and their relationships with each volunteer's behavioral response. The results of this project will help understand the electrophysiological mechanisms involved in the display of MQT (or the visualization of a visual illusion) in different spatial regions or the modification of its constituent elements and may establish a baseline for this phenomenon in a sample of healthy volunteers.

7
  • FRANCISCO WILSON NOGUEIRA HOLANDA JÚNIOR


  • Worry: Psychobiological, Psychometric Aspects and their Relationship with Cognitive and Behavioral Variables

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • JONAS JARDIM DE PAULA
  • FIVIA DE ARAUJO LOPES
  • NEUCIANE GOMES DA SILVA
  • REMERSON RUSSEL MARTINS
  • VALESCHKA MARTINS GUERRA
  • Data: 22-jun-2023


  • Resumen Espectáculo
  • Worry is defined as a chain of predominantly verbal thoughts, whose contents are about future events with some degree of uncertainty. At an atypical level, concerns become persistent, pervasive, uncontrollable, and are associated with distress and functional impairment. There is a scarcity of measures that assess this construct, as well as the need for more evidence on the relationship between worry and other behavioral and cognitive variables. In order to expand the body of evidence on the phenomenon of worry, based on four articles that make up the thesis, this research aimed to review the role of worry from the Tinbergen’s four questions (Study I), to develop and investigate the properties psychometric measurements of an inventory to assess worries (Study II), to analyze the role of worry and sleep complaints in cognitive failures (Study III), to verify the relationship between worry, unpredictability beliefs, neuroticism and uncertainty intolerance (Study IV), and to explore the structural dynamics of worry based on network analysis (Study V).  Study I showed that the application of the four levels of explanation of behavior (e.g., mechanisms, ontogeny, adaptive function, and phylogeny) allows a multifaceted understanding of worry. In Study II, the Worry Assessment Inventory (WAI) was developed, consisting of 21 items based on content validity. The two-factor model provided the best fit and plausibility for the WAI. Evidence on concurrent and convergent validity, measure invariance for gender, internal consistency, and test-retest reliability was provided. Regarding Study III, it was found that worry leads to more cognitive failures. Worry and sleep problems correlated strongly. Sleep problems did not have a significant effect on cognitive failures at a latent level. In Study IV, results indicated that higher unpredictability beliefs about self, people, and the world predicted more intolerance of uncertainty and worry mediated by neuroticism traits. Intolerance of uncertainty mediated the effect of neuroticism on worry.
    The Study V verified that the worry network is multifaceted and varied, with everyday functional impairment related to worrying being the most prominent and influential element.  In general, the set of studies presented here offers a new measure of worry and expands and provides new evidence on worry and how this construct relates to other behavioral and cognitive variables.

8
  • GÊNEDY KARIELLY DA SILVA APOLINÁRIO
  • Role of hippocampal CaMKII in object recognition memory processing

  • Líder : MARTIN PABLO CAMMAROTA
  • MIEMBROS DE LA BANCA :
  • MARTIN PABLO CAMMAROTA
  • ELAINE CRISTINA GAVIOLI
  • VANESSA DE PAULA SOARES RACHETTI
  • JORGE HORACIO MEDINA
  • GRACE SCHENATTO PEREIRA MORAES
  • Data: 12-jul-2023


  • Resumen Espectáculo
  • Consolidation stabilizes learned information in long-term memories (LTM) through a protein synthesis and gene expression dependent process. LTM can be destabilized when recalled and must go through a “de novo” protein synthesis and gene expression dependent process called reconsolidation. Reconsolidation takes place in two phases and acts on an already existing mnemonic trace. The first phase, named destabilization, leaves the reactivated mnemonic trace in a malleable and modifiable state, while the second one, named restabilization, allows the mnemonic trace to become stable again. Object recognition memories (ORM) are declarative representations essential for remembering common sense information and autobiographical episodes. In fact, one of the first symptoms of Alzheimer's disease is a decline in this type of memory. In recent decades, the study of hippocampal synaptic proteins has been fundamental for a better understanding of the molecular mechanisms of memory. However, the role of these proteins in ORM reconsolidation remains inconclusive. We investigate the role of hippocampal calcium/calmodulin-dependent protein kinase II (CaMKII) in ORM processing. Our results shows that in rats (1) CaMKII is required for ORM consolidation, CaMKII activity is necessary for ORM destabilization, but not for ORM restabilization, (2) ORM destabilization requires GluN2B NMDAr activity to occur, suggesting an important interplay between CaMKII and NMDAr, (3) ORM destabilization induces coupling of theta-gamma oscillation which is blocked by CaMKII inhibition. We understand that CaMKII activity is unprecedented for physiological processes and, therefore, that the understanding of CaMKII role in memory is crucial to the better comprehension of how neurological disorders develop.

9
  • SAMARA BEZERRA ALMEIDA
  • Vocal ontogeney and structure of giant otter pups in the hydrographic basin Tocantins-Araguaia

  • Líder : RENATA SANTORO DE SOUSA LIMA
  • MIEMBROS DE LA BANCA :
  • RENATA SANTORO DE SOUSA LIMA
  • LUANE MARIA STAMATTO FERREIRA
  • IGNACIO SANCHEZ GENDRIZ
  • GUILHERME DE MIRANDA MOURÃO
  • VERA MARIA FERREIRA DA SILVA
  • Data: 31-jul-2023


  • Resumen Espectáculo
  • One of the foundations that structures and keeps cohesive animal societies is communication. The giant otter is a social animal that maintains group cohesion using vocal communication. Groups of giant otters defend territories along water bodies using acoustic and chemical signals. There is evidence of the existence of the vocal signature and individual recognition for the species. However, the vocal ontogeny of the giant otter remains poorly understood as well as the variation in the structure of the vocal repertoire. This work aims to investigate the vocal behavior of giant otter cubs, seeking to explore ontogenetic and functional issues in the Tocantins-Araguaia watershed (Cantão State Park), Tocantins state, Brazil. We recorded the sounds with a directional microphone from a minimum distance of 10m and a maximum of 50m and increased the sample using a Song Meter SM3 recorder at the entrance of the sighs of the giant otter burrows and five camera traps. We carried out 28 campaigns, and the campaigns lasted an average of 7 days, with an average of 12 hours in the field per day, totaling 2,688 hours of effort in the field. Otters are highly vocal from birth. Otter pups follow sequences of moans and yelps that can be characteristic of immature calls. Here we present a review of the classification of 16 vocal types found for spider pups and we associate the vocal repertoire with the age stage of these free-living pups. We also present three new types of sound that have not yet been heard for young spider spiders. Some vocal types such as: Cub call, Growl, Scream and Coo call appear in the first stage of life and remain until adulthood. Characteristically, how changes in the development of child production since birth (ontogeny) can bring information about the physiological and social factors that can influence such changes. In addition, this characterization is an important tool for preparing management plans in the natural environment, as well as helping to guide human activities involving the species, such as ecotourism.
10
  • RAFAEL VITOR LIMA DA CRUZ
  • Effects of N,N-Dimethyltryptamine on the Phenotype and Diathesis of Depression: A Laboratory Longitudinal Study using C57BL6 Mice

     

  • Líder : RICHARDSON NAVES LEAO
  • MIEMBROS DE LA BANCA :
  • THIAGO CAVALCANTE MOULIN
  • DRAULIO BARROS DE ARAUJO
  • EMELIE KATARINA SVAHN LEAO
  • HINDIAEL AERAF BELCHIOR
  • LYVIA LINTZMAIER PETIZ
  • Data: 31-jul-2023


  • Resumen Espectáculo
  • Depression is a neurological disorder that affected 4.4% of the global population in 2017. It is characterized by apathy and anhedonia, which significantly impact the social and professional life of those afflicted. The etiology of depression has not been fully elucidated, although genetic, humoral, environmental, and behavioral factors have been correlated with its development. The conventional treatment typically involves slow-acting serotonergic drugs that often have side effects more detrimental to the clinical condition than the symptoms themselves. In the past two decades, the Neurogenic Hypothesis of Depression has linked the production of new neurons in the adult hippocampus to the neurobiological mechanism essential for alleviating symptoms by classical antidepressants. Concurrently, psychedelic drugs have reemerged as a category of molecules capable of enhancing neuronal plasticity. Unfortunately, the hallucinogenic properties of these compounds, despite their clinical utility, have hindered their widespread assimilation. At this stage of psychedelic research, it is necessary to understand the involvement of the subjective experience, the psychedelic experience, in the therapeutic potential of these compounds. This understanding will enable us to focus on delineating more effective, accessible, and comprehensive ways of applying these compounds to populations. In this study, we induced depression in mice using the Unpredictable Chronic Mild Stress model. We evaluated how a single dose of the psychedelic N,N-Dimethyltryptamine (DMT) affects the symptoms and humoral biomarkers of depression. Additionally, we examined whether being conscious during the hallucinogenic phase is necessary for DMT to exert its neurotrophic effect by administering the drug to anesthetized animals.

11
  • NÍVIA DE ARAÚJO LOPES
  • Motivation and conscious consumption: contributions of evolutionary theories applied to human behavior

  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • RENATA PEREIRA DE FELIPE
  • ARRILTON ARAUJO DE SOUZA
  • FELIPE NALON CASTRO
  • RAQUEL FARIAS DINIZ
  • WALLISEN TADASHI HATTORI
  • Data: 29-sep-2023


  • Resumen Espectáculo
  • Studies indicate that current consumption forms are influenced by specific motivating systems. In the evolutionary perspective, the fundamental social motives helped in the survival and reproduction of the individuals in the environment of evolutionary adaptation of the humans. The objective of this work is to investigate the relationship between basic motivations and conscious consumption, considering attitudes, consumption behavior, personal and socioeconomic characteristics and the perception of subjective well-being. Through the application of an instrument that investigates the fundamental social motives and the behavior of conscious consumption, among other information, the tests of the hypotheses of the study will be carried out. It is expected, in the end, an understanding of how human motivation systems can act on conscious consumption behavior in different ages and audiences.

12
  • PHIETICA RAISSA RODRIGUES DA SILVA
  • SUSTAINABILITY IN RIBEIRINHOS: HOW ECONOMIC GAMES CAN HELP UNDERSTAND THE SOCIAL BEHAVIOR BEHIND SUSTAINABLE DEVELOPMENT

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • FELIPE NALON CASTRO
  • PRISCILA FABIANA MACEDO LOPES
  • NATÁLIA BEZERRA DUTRA
  • ULYSSES PAULINO DE ALBUQUERQUE
  • Data: 06-dic-2023


  • Resumen Espectáculo
  • Cooperation is a central feature of human societies. It occurs when an individual has a cost for another individual to receive a benefit. Costs and benefits are measured in terms of fitness. In a population of cooperators, defecting individuals have a higher average fitness than cooperating individuals. However, in a competitive context, populations of cooperators may have a greater fitness than populations of selfish individuals. Adaptive mechanisms can contribute to the evolution and maintenance of cooperation, such as Kin Selection and Direct Reciprocity. To maximize their gains, individuals can use a public good without contributing to its maintenance, but it will increase the costs for other individuals, thus constituting a social dilemma. One way to study sustainable social dilemmas is through economic games. The aim of this work is to investigate cooperation mechanisms that regulate common goods use in communities from a sustainable development reserve. The Ultimatum Game, Dictator Game, Gift Game, Public Goods Game and Third-part punishment game were used to assess cooperation and resource management. A questionnaire on day-to-day cooperation and a norm conformity scale were also carried out. Furthermore, situations that facilitate the management of natural resources in a sustainable way will be observed, such as adherence to the fishing agreements norms. We investigated whether cooperation strategies vary according to the degree of kinship, level of interaction and reputation within the group. Our results showed that kinship is the most influential cooperative mechanism within this population, that direct reciprocity is present in everyday interactions, a good reputation favors gains within the group and a low relationship between cooperation in games and conformity to norms. From these findings, a long-term cooperation plan in a more sustainable system can be proposed, overcoming some cooperation dilemmas.

13
  • NATÁLIA DE ARAÚJO MIRANDA TASSO
  • THE ROLE OF THE PERCEPTION OF UNPREDICTABILITY, HARM AND FAMILY SUPPORT IN THE EXPRESSION OF FUNDAMENTAL REASONS AND SUBJECTIVE WELL-BEING DURING THE PANDEMIC
  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • FIVIA DE ARAUJO LOPES
  • RENATA PEREIRA DE FELIPE
  • ROSANA SUEMI TOKUMARU
  • WALLISEN TADASHI HATTORI
  • Data: 13-dic-2023


  • Resumen Espectáculo
  • This work explores the effects of the Covid-19 pandemic on elements of human psychology, while also examining how perceived family experiences during childhood may have influenced psychological aspects during the pandemic. To achieve this goal, we conducted three independent studies, with the first and third being quasi-experimental and the second an exploratory study, all cross-sectional. Data were collected online, involving 127, 438, and 422 participants, respectively, in each of the studies. The first study demonstrated that both unpredictability experienced during the pandemic and perceived harm played a significant role in promoting self-protective and disease-avoidance behaviors, while also contributing to decreased subjective well-being. In the second study, perceived family unpredictability in childhood revealed impacts not only on the choice of life history strategies but also on the manifestation of fundamental motives, even during the pandemic. Finally, the third study highlighted that perceived family support in childhood emerged as the primary factor influencing the expression of higher levels of subjective well-being and lower levels of self-unpredictability, while suggesting that the pandemic may have heightened the perception of unpredictability in relation to the world, as observed in our sample. In summary, the work provides insights into some of the effects of the pandemic, highlighting the interconnections between childhood experiences, life history strategies, behavioral expressions, and subjective well-being in a global crisis scenario. This integrated perspective enhances our understanding of the factors that influenced the observed human behavioral plasticity during the pandemic.

14
  • DANIELLA BEZERRA DOS SANTOS
  • Self-efficacy, self-expansion, and perceived market value: An evolutionary assessment of self-perceptions and relationships.

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • VICENTE CASSEPP BORGES
  • ALEXSANDRO LUIZ DE ANDRADE
  • ANTHONIETA LOOMAN MAFRA
  • FIVIA DE ARAUJO LOPES
  • MAURO DIAS SILVA JÚNIOR
  • Data: 20-dic-2023


  • Resumen Espectáculo
  • Self-perceptions have a major role in humans’ lives, being influenced by previous experiences and the context in which the person is inserted in, as well as influencing future outcomes in several areas of one’s life. Among the self-perceptions, there are two specific ones that have a considerable relevance when it comes to human motivations, both in our evolutionary history and our modern lives, Self-efficacy and Perceived Mate Value. Self-efficacy is related to the abilities someone has to achieve success, which can be related to survival skills, resources acquisition, forming the sense of competence an individual has about himself/herself on a diverse set of contexts. Whereas Perceived Mate Value is a self-evaluation that allows people’s adjustment to the options available on the mating market, increasing their chances of reproductive success. On this perspective, although several studies have demonstrated the potential use of Self-efficacy on the investigation of several different behaviors and contexts of human life, its participation on the Perceived Mate Value development, as well as its implications on the demand levels towards romantic partners, are still non-existent on the literature. Due to this reality, our main goal was to investigate the relationship between Self-efficacy levels and Self-perceived Mate Value, besides bringing an approach on how Self-efficacy presents itself on a population in which there is a constant demand for competence and adjustment: college students but not restricting to them, once we propose an even wider investigation while assessing this relation on a non-college population, also an analyses of self-efficacy in groups of people on regular global health conditions and during a pandemic moment; we also bring the assessment of self-efficacy on people previous and then after particular stimuli exposure, an effect known as Priming. The present work also innovates by producing by bringing evidence of validity to the Self-expansion Scale for Brazilians, we consider such scale speaks directly to our approach by connecting the notion of personal skills acquisition through intimate relationships. Therefore, the present work offers information on the motivation for competence (represented by Self-efficacy), its evolutionary basis and how it is presented on the context of college demands (Chapter 1); empirical research on the relation between Self-efficacy levels, Perceived Mate Value and the characteristics desired on an idealized romantic partner (Chapter 2); in addition to an empirical study on the potential association between someone’s Self-efficacy levels and how he/she evaluates his/hers partner attractiveness and the attractiveness of an idealized partner (Chapter 3); study developed with the aim to expand our analysis proposal to a more diverse population, assessing the potential relation between Self-efficacy and Perceived Mate Value in a non-college-restrict population (Chapter 4); investigation on the Priming Effect on people’s Self-efficacy perception (Chapter 5); an empirical study which proposes the assessment of people’s Self-efficacy levels before and during COVID-19 pandemic (Chapter 6) and lastly, Validation work on the Self-expansion Scale for Brazilians (Chapter 7).

15
  • DIANA CARVALHO DE FREITAS
  • Cetaceans in the Blue Amazon: occurrence, bioacoustic patterns and conservation
  • Líder : RENATA SANTORO DE SOUSA LIMA
  • MIEMBROS DE LA BANCA :
  • RENATA SANTORO DE SOUSA LIMA
  • CAMILA DOMIT
  • MARIA ISABEL CARVALHO GONÇALVES
  • FERNANDA SCARANO CAMARGO
  • RODRIGO HIPÓLITO TARDIN OLIVEIRA
  • Data: 22-dic-2023


  • Resumen Espectáculo
  • Cetaceans can be found in oceanic, coastal, estuarine and river regions throughout the world. And despite the ecological importance of this group, essential information such as distribution and occurrence patthers are still scarce, especially for species with oceanic habits. The main objective of this thesis is to contribute to the understanding of the occurrence and bioacoustic patterns in sound emission from cetaceans in areas with little sampling effort, especially in the oceanic zones of the Northeast region of Brazil. Chapter 1 of this document deals with the occurrence of humpback whales in an area further north of the use limit considered for the species on the Brazilian coast. The presence of humpbacks was recorded through Passive Acoustic Monitoring carried out in the Barreirinhas Basin, Maranhão, in 2016. Here, we describe the songs of the males and compare the units sung with the song composition of the males from Itacaré, Bahia. We conclude that the singing males from the Barreirinhas Basin belong to Reproductive Stock A, the only stock that occurs on the Brazilian coast, and we suggest an expansion of the area that is commonly considered to be used by stock A. In chapter 2, we describe an unprecedented visual and acoustic record of melon-headed dolphins in the equatorial portion of the South Atlantic Ocean. The observed group had 300 to 400 individuals and was moving quickly, with occasional jumps. We present the acoustic parameters of 225 dolphin whistles and compare these data with records made of the species in other oceans. The frequencies of the whistles ranged from 4.74 to 31.47 kHz and the duration of the whistles from 0.03 to 2.80 seconds, with a mean (±SD) of 0.44 seconds (±0.40 seconds). In chapter 3, we present the acoustic parameters of 1,212 whistles of the pantropical spotted dolphin in two areas with different latitudes, the first in low latitudes close to the equator (02°-05°S), an area where there was no acoustic record for the species, and another area at latitude 14°S. In univariate tests, for the 10 acoustic parameters evaluated, 7 showed a significant difference between areas. And in the quadratic discriminant analysis this difference was also confirmed. We conclude that latitudinal variation and physical and oceanographic differences between the two environments can act as selection forces, shaping the acoustic behavior of the species in different habitats. In the final chapter, our objective was to answer the following question: are Brazil's marine protected areas delimited where there is the highest occurrence and density of cetaceans? We observed that the majority of conservation areas are coastal, with only seven Marine Protected Areas (MPAs) located after the shelf break. Therefore, we conclude that the current distribution of MPAs in Brazil is not sufficient and representative to cover the entire diversity of cetaceans that occur in our waters, especially in oceanic regions.

2022
Disertaciones
1
  • JAMILE MOREIRA MEIRA
  • Protective potential of Tempol against  harmful alcohol effects on zebrafish behavior

     


  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • STEFANI ALTENHOFEN
  • ANA CAROLINA LUCHIARI
  • LUIZ FERNANDO DE FARIAS JUNIOR
  • Data: 23-mar-2022


  • Resumen Espectáculo
  • Alcohol is one of the most consumed licit drugs in the world. However, this drug's indiscriminate and excessive consumption brings great social, economic, and health damages. Currently, it is believed that part of the deleterious effects of alcohol is consequences of the exacerbated production of "reactive oxygen species", molecules that affect the normal homeostasis of the organism. In this work, we tested whether the use of a synthetic antioxidant substance, tempol, could reduce or even eliminate the harmful effects of alcohol in the body since antioxidants have the potential to reduce the number of reactive oxygen species. Thus, we focused this study on evaluating the protective potential of tempol in a cognitive context (memory test) and a stressful situation. For this, we used an animal model already established in the field of psychopharmacology, the zebrafish. The animals were treated with tempol, alcohol, tempol + alcohol, and water (control group). We used the protocol of memorization and discrimination of objects to evaluate how the tempol could reduce the deleterious effects of alcohol in the formation and recovery of memory in the animals. Our results indicate that there was impairment in the discrimination of objects by the alcohol group, but both the tempol group and the tempol + alcohol group showed greater exploration of the new object, indicating that they could discriminate. In another step, the animals were submitted to unpredictable chronic stress treatment and tested for locomotor and anxious-like behavior after treatment with tempol. We observed that the locomotor parameters of the groups not stressed and treated with alcohol and tempol + alcohol were lower than the other groups. As for the anxiety response, the unstressed groups of the control and tempol treatment had the smallest distances from the bottom of the aquarium. In general, our results indicate a protective activity of tempol for the harmful effects of alcohol on tasks requiring memory, but no effect in chronic stress situations, which may have resulted from low tempol concentration or low potency of the stress protocol used. We reaffirm the zebrafish as an experimental model for the search for new options for drugs that protect the nervous system, and we suggest that further studies seek to deepen the knowledge about the actions of time.

2
  • TAINAH PORPINO DE PAIVA COSTA
  • Effect of status motivation on higher education course choice
  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • ANDRÉ LUÍS RIBEIRO LACERDA
  • FELIPE NALON CASTRO
  • JESSICA JANINE DE OLIVEIRA
  • Data: 25-abr-2022


  • Resumen Espectáculo
  • The Fundamental Motivations approach suggests that humans are motivated to seek and maintain status. In Brazil, status can be acquired through professional advancement, as a result of access to higher education. This work investigated whether the status of the higher education course influences the choice of a profession; and whether factors related to the possession of resources influence this choice. A total of 810 individuals participated in the research; each took part in one of three studies. In the first study, 193 participants rated the status of different university courses. In the second study, 252 participants assessed the mate value, social status, and individual characteristics of stimulus subjects who had an academic background in low-status or high-status courses. Finally, in the third study, 365 undergraduate students provided information about their social class, status motivation, childhood environmental unpredictability, personality characteristics, and assessed the social status of the chosen course. The results indicated that courses related to personal urgencies are evaluated with higher social status. In addition, the diploma works as a marker of social and personality characteristics: stimulus subjects with a high-status diploma were evaluated with higher social status and socially aversive personality traits, while those with a low-status diploma were evaluated with pleasant and predictable personality traits. Finally, a positive correlation was found between higher education course status, status motivation and the Narcissism trait and a negative correlation between course status and the Psychopathy trait. This work expands the knowledge about status motivation and its influence on decision making outside the North American and European context. This information is important because career choice has a great influence on subjective and psychological well-being.

3
  • JOÃO LUCAS GARCIA DA SILVA
  • TELL ME WHAT YOU CONSUME AND WILL SAY AS YOU ARE. CULTURAL PRODUCTS AS AN ATTRACTIVITY, STATUS AND SOCIAL DOMINANCE INDICATIVE
  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • FIVIA DE ARAUJO LOPES
  • JEAN CARLOS NATIVIDADE
  • Data: 26-abr-2022


  • Resumen Espectáculo
  • The present study aims to verify if the consumption of Premium cars influences the self-perception of the mating value, social status and the level of social dominance of the individual. For this, 252 heterosexual participants of both sexes, aged between 18 and 70 years old, will evaluate themselves about their mating value, orientation to social dominance and subjective social status. Each participant must take part in one of three experimental conditions: (1) those who do not own a car, (2) who own a non-premium car and (3) who own at least one premium car. All participants will answer anonymous and individual questionnaires that will be applied through an online platform. We believe that work helps us to broaden our understanding of the relationship between consumption choices and self-perception of individual characteristics. The assessment of consumption and its effects on individuals' self-perception allows us to test hypotheses and contributes to the elaboration of current consumer decision-making models, in addition to informing consumers about the direct and indirect consequences of their choices in the social environment.
4
  • ARTHUR MEDEIROS CAMARA
  • RELATIONSHIP OF COMMUTE TIME TO SCHOOL, SCHOOL SHIFT AND LEVEL OF URBANIZATION WITH SLEEP HABITS AND COGNITIVE PERFORMANCE IN ADOLESCENTS FROM AN INTEGRATED TECHNICAL HIGH SCHOOL.
  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • JANE CARLA DE SOUZA
  • ÉRICO FELDEN PEREIRA
  • Data: 06-may-2022


  • Resumen Espectáculo
  • Adolescents show a delayed sleep phase related to biological and psychosocial factors, leading to a contrast between sleep habits and morning school hours, which leads to sleep deprivation and irregularity. This in turn can harm their cognitive and school performance and overall health. Attention and memory may be among the impaired cognitive processes. School commuting time and the degree of urbanization from where they live are related factors. This study aims to analyze the relationship of the duration of commuting to school, school shift and level of urbanization with the sleep-wake cycle and cognitive performance of adolescents. A total of 291 students participated in the study (15.4 ± 0.9 years; 59.5% women; 242 completed all stages), recruited from two units of a technical high school in RN: Natal, metropolitan region, and Lajes, less urbanized area. Sleep habits were assessed using the questionnaires: “Health and Sleep”, the Pittsburgh Sleep Quality Index, the Pediatric Daytime Sleepiness Scale, and sleep diaries with Maldonado Sleepiness Scale completed over 10 days. In this interval, from Tuesday to Friday, the Continuous Performance Task (assessing attention) and the Sternberg Task (working memory) were applied. Higher commuting times were associated with waking up (B=-0.66, p<0.001) and going to bed earlier in weekdays (B=-0.37; p=0.02) and weekends (B=- 0.4; p=0.03), having less total time in bed in 24 hours in weekdays (B=-0.31; p=0.04), greater irregularities in wakeup times (B=0.19; p =0.04), time in bed at night (B=0.45; p=0.03) and in 24 hours (B=0.48; p=0.02), worse sleep quality (B=0 .02; p=0.009), lower percentage of correct responses for memory in the 6-digit (answer: “yes”) (B=-0.09; p=0.02) and 5-digit (“no”) lists (B= -0.07; p=0.03). Morning shift students woke up (B=-181; p<0.001) and went to bed earlier in weekdays (B=-78; p<0.001) and weekends (B=-30; p<0.03), had shorter time in bed at night (B=-101; p<0.001) and in 24h (B=-91; p<0.001) in weekdays, greater irregularities in wakeup times (B=39; p<0.001), in time in bed at night (B=118; p<0.001) and in 24h (B=108; p<0.001), higher levels of social jet lag (B=31; p<0.001), worse sleep quality (B=1, 33; p=0.01) and fewer correct responses in 5-digit lists (“yes”) for memory (B=-8.69; p=0.01). Individuals residing in the less urbanized region woke up (B=-28; p=0.02) and went to bed earlier in weekdays (B=-48; p<0.001) and weekends (B=-28; p=0 .05), showed longer times in bed in 24 hours in weekdays (B=24; p=0.04), fewer correct answers in lists of 5 (B=-7.8; p=0.01) and 6 digits (“yes”) (B=-7.3; p=0.03) for memory, lower percentage of correct answers in tonic alertness (B=-2.67; p=0.02), phasic alertness (B=-5 .16; p=0.04) and selective attention (B=-5.78; p=0.02), but shorter reaction times for correct responses of phasic alertness (B=-54.81; p=0.01). Thus, the hypothesis that school routine and the degree of urbanization may have an impact on sleep habits and working memory in adolescents is confirmed, while attention was only related to the degree of urbanization.
5
  • BÁRBARA FLORIPES DO NASCIMENTO
  • GG! Can online games offer me a buff? Individual factors and online game choices

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • MARIA EMILIA YAMAMOTO
  • WALLISEN TADASHI HATTORI
  • Data: 26-jul-2022


  • Resumen Espectáculo
  • Online games have been showing a significant increase in use nowadays, attracting the most different ages and profiles of players due to the infinite possibilities offered by the virtual environment, making it possible not only to carry out common day-to-day activities, but also surreal experiences. In the literature, several benefits provided by games are discussed, such as the formation of new social bonds and the strengthening of existing bonds, in addition to the improvement of cognitive skills, among others. On the other hand, negative effects are also recurrent, making it necessary to understand how both affect players. With that in mind, this work carried out a theoretical review of human evolution in terms of behavior in games and our biological needs, and analyzed the personality and motivations to play of 405 players of different types of games and what would be associated with problematic use about the game. Our results reinforced what the literature already has on the subject, showing some personality traits and specific motivations as precursors to the emergence of negative behaviors from games. Some limitations of the work are discussed, as well as the need for studies with players from different cultures, as well as a better delimitation of game styles and their respective characteristics.

6
  • ANA GABRIELA AMARAL DOS SANTOS
  • CONSCIOUS CONSUMPTION: EXHIBITION OF LUXURY CARS IN THE MATCHING CONTEXT PERCEPTION OF ATTRACTIVENESS AND SOCIO-SEXUAL AND SOCIO-SEXUALITY USERS OF PUBLIC OR PRIVATE TRANSPORT

  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • ANTHONIETA LOOMAN MAFRA
  • FELIPE NALON CASTRO
  • FIVIA DE ARAUJO LOPES
  • Data: 26-jul-2022


  • Resumen Espectáculo
  • Luxury products can be defined as signs displayed to please observers, and in the
    background they assume their material functions and are therefore termed products of
    conspicuous consumption. Car owners report several arguments to justify their
    consumption decision. The relevance of using automobiles as a model to investigate the
    effect of luxury products on the perception of attractiveness and sociosexuality is given
    by the fact that they meet the necessary requirements to function as a conspicuous sign
    and be a model widely described in the literature. Based on this, this study was designed
    with the main objective of investigating whether vehicle consumption affects the
    perception of attractiveness and sociosexual attitude of third parties, as well as the
    sociosexuality of individuals who use public or private transport. For this, a total of 278
    Brazilian subjects participated in this study. Each participant answered a questionnaire in
    which they rated six stimulus subjects (SS) of the opposite gender, each profile consisting
    of a photo and a description. They rated each SS's attractiveness to (a) a casual
    conversation, (b) a short-term relationship, and (c) a long-term relationship and described
    the SS's attitude according to the revised Sociosexual Orientation Inventory (SOI- R). For
    statistical analysis, General Linear Models (GLM) and Bonferroni's Post Hoc tests were
    applied. For casual conversation, SS who do not own a car were more attractive than those
    who own a popular or luxury car. For short-term relationships, there was an interaction
    effect between the participants' means of transport and the treatment. For participants with
    private transport, SS with luxury automobiles were more attractive than for participants
    who travel by public transport. For long-term relationships, the effect found was similar.
    In the SS who do not have a car or who have a popular car, for casual meeting and
    marriage, no differences were observed. In these two types of relationship there was a
    difference between men and women, however men were more sensitive to this stimulus

    when compared to women. Subjects who own a luxury car had higher sociosexuality,
    compared to those who own a popular car or those who do not. There were no differences
    between the sociosexuality of those who did not have a car and those who owned a
    popular car. In the analysis of the participants' sociosexuality levels, there was an
    interaction between the participants' sex and the means of transport in sociosexuality.
    Men who travel privately had a higher sociosexuality score than men who travel by public
    transport; among women, no difference was observed. This study represents an advance
    in evolutionary psychology research that seeks to better understand human behavior,
    communication, preferences and motivations.


7
  • STEPHANIA RUTH BASILIO SILVA GOMES
  • PREDICTIVE ANALYSIS OF CHRONOBIOLOGICAL VARIABLES AND COMORBITY INDICATORS FOR MENTAL HEALTH OUTCOMES: A MACHINE LEARNING APPROACH

  • Líder : MARIO ANDRE LEOCADIO MIGUEL
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • FELIPE BEIJAMINI
  • MARIO ANDRE LEOCADIO MIGUEL
  • Data: 26-jul-2022


  • Resumen Espectáculo
  • Introduction: studies have shown high incidences of depression worldwide and its co-occurrence with several important medical conditions, especially in middle-aged and elderly subjects. In this multimorbidity scenario, depression is commonly associated with diseases related to metabolic syndrome, such as obesity and diabetes. Chronic alterations in circadian sleep-wake rhythm represent a relationship with the development of depression and its associated comorbidities, as they favor the breakdown of the internal temporal organization of essential physiological and metabolic processes. Currently, making accurate clinical diagnoses and screenings have been a persistent challenge in mental health, due to the use of limited traditional tools that do not include additional characteristics of important clinical data of the patient, including objective observations of disease biomarkers. Objective: Thus, the objective of the present study was to detect depressive symptomatology from general biomarkers of obesity and diabetes, as well as variables related to sleep and physical activity, in middle-aged and elderly adults, through a learning approach of machines. Method: Data from the Global Physical Activity Questionnaire (GPAQ - physical activity level), from the Patient Health Questionnaire (PHQ-9), and from the sleep habits questionnaire were extracted from the National Health and Nutrition Examination Survey database (NHANES) in the period 2015-2016. Other variables were accessed and used as predictive resources, such as anthropometric measurements and plasmatic biomarkers of obesity and diabetes. Three supervised learning algorithms were implemented: Penalized Logistic Regression with Lasso (RL), Random Forest (RF) and Extreme Gradient Boosting (XGBoost). Results: The XGBoost model provided greater accuracy and precision (87%), with a proportion of correct answers in cases with depressive symptoms above 80%. In addition, daytime sleepiness was the most significant predictor variable for predicting depressive symptoms. Conclusions: Sleep and physical activity variables, in addition to obesity and diabetes biomarkers, together assume significant importance in predicting, with an accuracy and precision of 87%, the occurrence of depressive symptoms in middle-aged and elderly individuals.

8
  • JOÃO PAULO MEDEIROS MAMEDE
  • Bold and Shy individiual differences in zebrafish: is there reliability between behavioral profiles?
  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • MARTA CANDEIAS SOARES
  • ANA CAROLINA LUCHIARI
  • PERCILIA CARDOSO GIAQUINTO
  • Data: 01-sep-2022


  • Resumen Espectáculo
  • Behavioral variation between individuals is related to the species biology and the life history of each individual. While boldness is the most studied behavioral dimension in animals, evaluations of behavioral consistency over time and between contexts, as well as which differences matter for separating profiles are still debatable. Here, we divided zebrafish into bold and shy profiles by applying an emergence test (black to white entrance) three times with the same population of fish. The two groups formed (bold and shy) went through six different behavioral tests: novel tank, open field, sociability, novel object, aggressiveness, and black and white preference, which were employed twice, with an interval of 30 days. Bold animals showed less anxiety-like behavior and higher aggressiveness compared to shy animals, and this pattern remained consistent over time for these two aspects. These features were considered the main factors to classify zebrafish into bold and shy profiles. In addition, the consistency appeared to be context-dependent. The differences noted in the behavioral profiles allowed us to understand how individuals behave facing environmental challenges. in different situations.
9
  • JOAQUIM BRUNO CRUZ NETO
  • Demography, nest occupation and social interactions of the ant Odontomachus haematodus
  • Líder : ARRILTON ARAUJO DE SOUZA
  • MIEMBROS DE LA BANCA :
  • ANA MARIA MATOSO VIANA BAILEZ
  • ARRILTON ARAUJO DE SOUZA
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • Data: 30-sep-2022


  • Resumen Espectáculo
  • Ants, eusocial animals, present a variety of society configurations. Such configurations are emergent properties of interactions between individuals and nest space occupancy, which influence many processes necessary to the development of the colony. Among ants, poneromorphs are appropriate models for the study of social configurations, due to their morphological characteristics and behavioral profile. This study is a characterization of nest occupancy and individual interaction patterns in Odontomachus haematodus colonies maintained in laboratory settings. Five colonies were kept in artificial nests in the Behavioral Biology Laboratory (LBC-DFS) at UFRN. The ants were marked for identification, and their behavior was registered and analyzed. In order to understand the dynamics of individual interactions we used analysis of social networks. Our results indicate a nest space utilization patterns related to the entrance distance. Chambers closest to the entrance were used by inactive individuals, which act as a “backup workforce”. Chambers further from the entrance were used for immature allocation. The analysis of the social networks showed the presence of individuals more connected than the others in every colony. This position does not seem to be associated with any particular behavioral pattern or function in the colony. We conclude that the social organization in colonies of O. haematodus relies on the existence of generalists, well connected individuals, that are capable of accessing the necessities of the colony.
10
  • REBEKA GUERRA DE OLIVEIRA
  • COPING & PERSONALITY UNDER AN EVOLUTIONARY PERSPECTIVE
  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • MARIA EMILIA YAMAMOTO
  • VALESCHKA MARTINS GUERRA
  • Data: 21-dic-2022


  • Resumen Espectáculo
  • Personality is characterized by individual differences and influences behaviors, and it can be related to the way of dealing with adverse situations, in Psychology, known as coping. As problems are inherent in everyone's lives, given the COVID-19 pandemic situation, a unique opportunity arose to assess the relationship between coping and personality traits, as this could bring to light important paths regarding to intervention recommendations, respecting such individual differences. The first chapter of this dissertation presents the theoretical foundations on the theme of personality traits and coping. The second article is empirical and focused on investigating whether coping strategies differ among people with different expressions of personality traits; if individuals who score differently on the measured traits show a difference in the difficulty of coping with the pandemic; whether there is a difference in the group of activities considered relaxing and stress-relieving practices in relation to different personality traits. We had the participation of 175 people, through online data collection, who answered four questionnaires: Sociodemographic; Big Five inventory; Toulousaine Coping Scale; Relaxing practices. The data obtained were statistically analyzed from the creation of clusters, application of ANOVA and Kruskal-Wallis tests. We observed that the ways of facing the pandemic and the impacts caused by it, as well as the choice of relaxing practices, differ according to the expression of different profiles and different personality traits. From the present work, it was possible to provide more information on the subject in situations of great collective commotion, in addition to suggesting specific guidelines, related to the choice of relaxing practices, in a more individualized way, with a view to increasing the success of possible interventions.

Tesis
1
  • GEOVAN FIGUEIRÊDO DE SÁ FILHO
  • EVALUATION OF THE MEDICINAL POTENTIAL OF THE METHANOLIC EXTRACTS OF THE CATINGUEIRA (Cenostigma bracteosum) AND CANAFÍSTULA (Senna trachypus) NATIVE PLANTS OF THE CAATINGA

  • Líder : JEFERSON DE SOUZA CAVALCANTE
  • MIEMBROS DE LA BANCA :
  • EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • JEFERSON DE SOUZA CAVALCANTE
  • JOSÉ RODOLFO LOPES DE PAIVA CAVALCANTI
  • LUANNE EUGÊNIA NUNES
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 02-feb-2022


  • Resumen Espectáculo
  • Considered one of the most biodiverse countries on the planet, Brazil has a diversity of species in fauna and flora, this is also a reflection of the territorial extent and diversity of biomes present. Among the biomes in the national territory, the Caatinga stands out for being an exclusively Brazilian biome, whose vegetation is one of the most threatened on the planet, and, despite this, they still do not have many botanical studies in this area, being a large part of these plants used by the population therapeutic purpose. In this sense, the objective of the present study is to evaluate the neuroprotective effect of methanolic extracts from leaves of catingueira (Cenostigma bracteosum) and canafístula (Senna trachypus), plants native to the Caatinga belonging to the Fabaceae family. For this, the leaves of catingueira (Cenostigma bracteosum) and canafístula (Senna trachypus) were separated, cataloged and labeled in plastic bags for processing in the laboratory. Then the process of maceration with the solvent methanol was carried out, to obtain the methanolic extracts. With the obtained extracts, it was possible to verify the presence of secondary metabolites, in addition these same extracts will be used to perform toxicological tests, hemolytic and anti-microbial activity, in addition to checking the neuroprotective potential. The results obtained in this study, about the neuroprotective potential of catingueira (Cenostigma bracteosum) and canafístula (Senna trachypus), two species of plants native to the Brazilian Caatinga, will enable the understanding of the true potential of these species of the Fabaceae family, which are already commonly used to treat various illnesses by the traditional local population.

2
  • MAYARA CRISTINA MOURA SILVA DOS PRAZERES SILVEIRA
  • Fish memory: cognition in reef fish

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • EDUARDO BESSA PEREIRA DA SILVA
  • ELIANE GONÇALVES DE FREITAS
  • LIANA DE FIGUEIREDO MENDES
  • PERCILIA CARDOSO GIAQUINTO
  • Data: 14-mar-2022


  • Resumen Espectáculo
  • Reef environments are highly complex, providing different types of environmental signals that need to go through processing steps to facilitate acquiring information and making decisions. Despite the existing myth around fishes' short memory and limited behavioral repertoire, for a long time considered only instinctive, the development of functions related to learning and memory is widespread among teleosts. These skills are crucial for survival in natural habitats. Many fish species can perform tasks from the simplest to the most complex. However, our knowledge about the variations involving task characteristics or the effects of environmental variables on cognitive processes is still scarce. The general objective of this thesis was to investigate factors related to the nature/complexity of the task in behavioral responses related to learning and memory in damselfish, using three species: Stegastes fuscus, Acanthochromis polyacanthus, and Amphiprion percula. We evaluated information retention time in appetitive and aversive conditioning tasks (chapter 1), We investigated the influence of familiarity on the mnemonic response maintenance over time (chapter 2), and We assessed spatial learning and memory in response to environmental warming (chapter 3). Our results showed that the nature of the stimulus does not seem to interfere with information retention for up to 15 days in S. fuscus, which sustain the mnemonic response 5, 10 and 15 days after aversive and appetitive conditioning. We observed that S. fuscus showed individual recognition and ability to remember conspecifics through the agonistic response, which was affected by the interval time for re-pairing with conspecifics (5, 10, and 15 days). In addition, we observed that A. polyacanthus learns and remembers a spatial navigation task for 5 days while A. percula does not learn the task. In this same task, the increase of 2°C damages memory while the increase of 4°C impairs the learning of A. polyacanthus. Given the vulnerability of reef environments, the understanding of aspects related to the learning and memory of individuals can provide science with valuable results for future management and conservation plans, in addition to contributing to the knowledge of the biology of damsels, which show an elaborate cognitive capacity.

     

     

     

3
  • SABINNE DANIELLE GALINA
  • RELATIONSHIP BETWEEN MORNING LIGHT EXPOSURE, SLEEP-WAKE CYCLE AND ATTENTION ON ADOLESCENTS FROM NATAL/RN.

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • FERNANDO MAZZILLI LOUZADA
  • JANE CARLA DE SOUZA
  • MARIO ANDRE LEOCADIO MIGUEL
  • RUBIA APARECIDA PEREIRA DE CARVALHO MENDES
  • Data: 19-abr-2022


  • Resumen Espectáculo
  • Psychosocial, behavioral and physiological changes related to adolescence contribute to a phase delay in the sleep-wake cycle (SWC). However, morning classes shorten sleep, causing partial chronic sleep deprivation and irregularity, resulting in excessive daytime sleepiness and impairing in cognitive and academic performance. Furthermore, SWC and attention present circadian variation and can be modulated by light-dark cycles. Therefore, this study aims to verify the existence of relations between morning light exposure and SWC and attention in adolescents studying in the morning shift in Natal, RN. The study included 99 adolescents of both sexes (63 girls), aged between 14-18 years (15.7±0.8 years), studying in freshmen and sophomore years of private high school. The students answered the “Health and Sleep” questionnaire and a Sleep Diary, containing the Maldonado sleepiness scale, and used an actimeter for 10 days. Actimetry collected data on SWC and light exposure. Attention was evaluated by a Continuous Performance Task (CPT), on a single application, between 7:30-9:30h during classes. In general, the sample presents poor sleep quality, sleep irregularity, sleep deprivation, and high social jetlag. On free days, high light intensities were associated with sleeping (B=-38.43, p<0.05) and waking up (B=-63.29, p<0.05) earlier on free days and regular time in bed (B=-51.34, p<0.05) as well as tendencies towards morningness (B=-24.91, p=0.07), less sleepiness when waking up on school days (B=-7.83, p=0.09) and regular waking up times (B=-17.67, p=0.09). In addition to shorter reaction time on tonic alertness (B = -32.87, p=0.05) and higher stability in sustained attention (B=-15.90, p=0.06). On the other hand, on school days, high light intensities were related to sleeping later (B=47.84, p<0.01) and shorter sleep duration (B=-41.43, p=0.01) and time in bed (B=-47.22, p<0.01), as well as longer reaction times on tonic (B=58.74, p<0.05) and phasic alertness (B=84.54, p<0.05), and selective attention (B=67.37, p<0.05). On the day of the CPT, high levels of sleepiness upon awakening were related to a higher frequency of omissions on tonic alertness (B=0.31, p<0.05), while lower sleep latencies related to higher percentage of correct responses on phasic alertness (B=-0.16, p<0.05). Furthermore, high light intensities between wake-up and entering the classroom were associated with longer reaction times on tonic alertness (B=95.51, p<0.05), selective attention (B=150.44, p <0.05) and a trend towards phasic alertness (B=53.08, p=0.08). Light during classes (between 7-9:30h) was not associated with changes in attention. Therefore, we suggest that there is a relationship between light exposure in the morning and SWC and attention in adolescents studying in the morning shift, which could contribute to advance rhythms and improve academic performance, however the temporal challenge related to the start of morning classes prevents this expression, masking the effects of light. Thus, additional studies with a larger sample size are needed to confirm these relationships.

4
  • ZOELIA CAMILA MOURA BESSA
  • Relation school shift with sleep habits and cognitive performance in adolescents of a technical high school in different urban contexts.
  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • HORACIO DE LA IGLESIA
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • FABIANA BARBOSA GONCALVES
  • FELIPE BEIJAMINI
  • MARIO ANDRE LEOCADIO MIGUEL
  • Data: 29-abr-2022


  • Resumen Espectáculo
  • The sleep-wake cycle of adolescents is characterized by a phase delay associated with biological, behavioral, and social changes, which are affected by school schedules. The aim of this study was to analyze the relationship between school shifts and sleep habits and quality, daytime sleepiness, and cognitive performance in adolescents from two urban contexts. A total of 294 adolescents from technical high school courses participated in the study, aged 15.3 ±0.8 years (175 girls/119 boys). A total of 133 went to classes in the morning shift and 161 in the afternoon shift. They were subdivided into two groups according to the degree of urbanization: less urbanized (Region 1) and more urbanized (Region 2). Sleep pattern was assessed by the following questionnaires: “Health and Sleep”, Pittsburgh Sleep Quality Index, Puberty and Phase Preference Scale, Pediatric Daytime Sleepiness Scale, in addition to a 10-day sleep diary. In these 10 days, cognitive tasks were performed to assess attention and working memory. Morning shift students showed earlier bedtimes (B=-72; p=0.00) and wake up times (B=-177.3; p=0.00) and had less time in bed (B=-103.7; p =0.00) in the week, worse sleep quality (B=1.5; p=0.00), greater irregularities in waking up time (B=43.3; p=0.00) and time in bed ( B=120.1; p=0.00) between weekdays and weekends, and higher rates of social jetlag (B=31.0; p=0.00), greater daytime sleepiness (B=1.5; p=0.04), greater frequency of naps during the week and predominance of school schedule as a reason for waking up comparing to those from the afternoon shift. Although students from the morning shift had a lower percentage of correct answers in selective attention (B=-5.5; p=0.03) and in tonic alertness (B=-2.0; p=0.09), they presented shorter reaction times in phasic alertness (B=-36.8; p=0.03). Regarding the degree of urbanization, students from Region 2 showed later bedtimes (B=-49.7; p=0.00) and wake up times (B=-31; p=0.01), had less time in bed (B=22.8; p=0.06) and greater sleepiness upon waking up (B=-0.7; p=0.00), as well as a greater occurrence of activities that favor alertness at night and longer reaction times in the phasic alertness (B=-46.7; p=0.01). However, they had a higher percentage of correct answers in tonic alertness (B=-4.1; p=0.00), phasic (B=-7.2; p=0.00) and selective attention (B=-10, 1; p=0.00); and lower percentage of omissions in tonic (B=1.5; p=0.04) and phasic (B=1.6; p=0.03) alertness. Overall, the tendency towards evening was associated with later bed (B=-5.4; p=0.00) and wake up times (B=-3.6; p=0.00), higher sleepiness (B =-0.3; p=0.00) and worse sleep quality (B=-0.2; p=0.00), without association with cognitive variables. There was no consistent relationship between the memory variables and the predictor ones. Thus, future studies using other working memory assessment tasks are needed to analyze this relationship. Therefore, our study confirms the hypothesis that the beginning of classes at 7:00 am is associated with impairments in sleep habits and attentional performance of adolescents, being affected also by the degree of urbanization. We suggest that educational opportunities experienced throughout life can affect the attentional performance of adolescents, which can differ between urban contexts.

5
  • LILLIAN NATHALIE OLIVEIRA DA SILVA
  • INFLUENCE OF THE IMMUNE SYSTEM ON OLFACTIVE SEXUAL ATTRACTION: PERSPECTIVES IN NON-HETEROSEXUAL RELATIONSHIPS

  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • FIVIA DE ARAUJO LOPES
  • HELLEN VIVIANNI VELOSO CORRÊA
  • JAROSLAVA VARELLA VALENTOVA
  • NICOLE LEITE GALVAO COELHO
  • Data: 04-ago-2022


  • Resumen Espectáculo
  • The influence of the Major Histocompatibility Complex (MHC), also known as HLA in humans (Human Leukocyte Antigen), has been extensively investigated in partner choice studies due to its fundamental role in the immune system and the odorous identity of individuals. These researches have verified the preference of individuals for odors of potential partners that have HLA molecules different from their own, and the hypothesis is linked to reproduction, as the immunological variety makes a possible offspring more resistant to various pathogens. Given the reproductive value, HLA research is limited to seeking evidence only in heterosexual couples, with no studies with different sexual orientations. Advancing in these studies, this work aimed to investigate the evolutionary reasons why HLA can influence olfactory sexual attraction in non-heterosexual people, testing the hypothesis that the influence must follow the existing patterns in heterosexual olfactory attraction and that the evolved psychological mechanisms are of the sex of origin, following the Parental Investment Theory regardless of sexual orientation. The methodology to verify the hypotheses was: a narrative literature review, two systematic reviews, and a quasi-experimental study. The results indicate that in a psychobiological panorama, variation is one of the fundamental pillars to study sexual behavior; that the process of choosing a non-heterosexual partner involves the same basic elements existing in heterosexuality, varying in intensity according to the level of parental investment of each sex and the appropriate environmental conditions for the choice of sexual strategies; that there is an interaction between olfactory sexual attraction and sexual orientation, with the latter influencing the preference and production of human body odors and these communicating clues about the sex and sexual orientation of potential partners; and that there is no male preference for odors from other HLA-like/different men, regardless of sexual orientation, as observed in heterosexual men evaluating the odors of women. These results confirm the hypotheses tested. The findings reinforce the classical evolutionary theories in the studies of sexual behavior and the need to treat and study sexuality in its plurality.

6
  • FELIPE PERNAMBUCO DA COSTA
  • MATE CHOICE THROUGH VISUAL CUES AND COLOR PREFERENCE IN THE PRAWN  Macrobrachium rosenbergii

  • Líder : DANIEL MARQUES DE ALMEIDA PESSOA
  • MIEMBROS DE LA BANCA :
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • ARRILTON ARAUJO DE SOUZA
  • VIRGINIA MARIA CAVALARI HENRIQUES
  • MARINO EUGENIO DE ALMEIDA NETO
  • VINÍCIUS DE AVELAR SÃO PEDRO
  • Data: 07-nov-2022


  • Resumen Espectáculo
  • The freshwater prawn Macrobrachium rosenbergii is a species of great economic importance. There are three adult male morphotypes in the species: small males can turn into orange claw males and these into blue claw males. However, there is little information about color preference and the importance of visual cues in mate choice in this species. Thus, this research seeks to analyze the preference for different colors in juveniles and adults and the role of visual cues in mate choice. We evaluated the preference of juveniles and adults for colors by placing the animal into an aquarium containing shelters of different colors to analyze the attraction of the prawn to them. For the analysis of the importance of visual cues in mate choice, we will first take photographs of the prawns and a river water environment. From these photographs, we will create computer stimuli that will correspond to figures with the exact coloration of the claw of a morphotype that will appear on a background that will correspond to the coloration of the claw of another morphotype or the coloration of the river water. We will display these stimuli to the prawns on a monitor. Defensive responses by the prawns will indicate that they are able to discriminate the color of the figure from the color of the background. Subsequently, we will analyze the mate choice in a four-arm experimental maze, through the preference of females for photographs of males of different sizes and colors of claw and the preference of males for photographs of females in different reproductive stages.

2021
Disertaciones
1
  • MARIA EDUARDA DE LIMA VIEIRA
  • Competition between colonies of Dinoponera quadriceps (Formicidae, Ponerinae)
  • Líder : ARRILTON ARAUJO DE SOUZA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • BENOIT JEAN BERNARD JAHYNY
  • NICOLAS GÉRARD CHÂLINE
  • Data: 01-feb-2021


  • Resumen Espectáculo
  • Competition is raised as a determinant factor for the organization of local ant community. Conversely, intraspecific competition is an occurrence with important ecological and evolutionary consequences, but its effect in natural populations remains uncertain. The goal of this research was to verify the intraspecific competition between colonies of the Dinoponera quadriceps in their natural habitat. Ten neighboring colonies of D. quadriceps were chosen within the secondary Atlantic Forest area in the Floresta Nacional de Nísia Floresta. The observations took place between July 2019 and February 2020. We observed one ant at a time, from the moment it left its nest until its return. Food collecting, agonistic interaction and chemical marking behaviors were registered using the All-occurrences sampling method. The displacement and places where these behaviors occurred were marked with numbered flags then measured with compass and tape. Results indicate that the colonies of D. quadriceps have foraging areas that do not form territories. In these areas, food collecting occurs with a higher frequency in overlap areas. The workers perform chemical marking unrelated to overlap areas between neighboring colonies. Agonistic interactions had a low frequency of observation, and were characterized by ritualized combat and were more frequent inside overlap areas. Abiotic factors (temperature, humidity, luminosity, rainfall) and biotic (food availability) had no direct influence on the conflicts between colonies.
2
  • EDUARDO MARIOSI VASCONCELOS
  • OVERCONFIDENCE: ASSISTANCE OR OBSTACLE? EVALUATING METAIGNORANCE FOR POLITICAL KNOWLEDGE

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • FELIPE NALON CASTRO
  • MAURO DIAS SILVA JÚNIOR
  • Data: 06-abr-2021


  • Resumen Espectáculo
  • Overconfidence is one of the most widely studied and discussed self-assessment biases in the literature. However, it is still not widespread in Brazil, with most of the works focusing on the area of behavioral finance. Much is discussed about the human tendency to exacerbate their own evaluations, the accuracy of which in judging their performance is reported as little or none. Some factors are pointed out as possible drivers of self-assessment biases, such as the subject's familiarity with the analyzed topic. Over the years, some results have been superimposed in the literature, and some terms end up covering more than one behavior. Therefore, measures of overestimation, overplacement, and overconfidence in 400 adults subjects were assessed in relation to their performance in a questionnaire on Brazilian political knowledge. The results indicated the existence of the studied behaviors, but to a lesser extent than previously reported in the literature. The methodological aspects involved in the study of these biases are discussed, and the possible factors associated with the exacerbation of previous results.

3
  • FERNANDA MAYARA CRISPIM DIOGO
  • RELATIONSHIP BETWEEN HABITS AND SLEEP QUALITY, COGNITIVE PROCESSES AND BODY AND VISCERAL FAT LEVELS IN POSTGRADUATE STUDENTS

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • JANE CARLA DE SOUZA
  • SABINE POMPÉIA
  • Data: 20-may-2021


  • Resumen Espectáculo
  • Insufficient and irregular sleep is a common problem for modern society, whether due to sleep disorders, stress and / or academic and social demands. This situation can impair the performance of daily activities and generate health problems. Postgraduate students are likely candidates for sleep deprivation and irregularity because they are subject to stressful situations and high academic demand. Studies have pointed out that poor sleep habits lead to deprivation and low sleep quality, in addition to irregular sleep schedules, which can lead to circadian desynchronization, causing an increase in daytime sleepiness. It can also lead to impairment of basic cognitive processes, such as attention, working memory, inhibitory control and cognitive flexibility. Insufficient and irregular sleep are also risk factors for obesity, diabetes and cardiovascular diseases. This work aims to characterize sleep habits and quality of postgraduate students, relating them to cognitive processes and levels of body and visceral fat. 68 students from postgraduate programs in the area of biosciences of a public university will participate in the study. Participants will complete questionnaires about sleep habits, chronotype, sleep quality, daytime sleepiness and will perform tasks to assess cognitive processes, in addition to measures of body indexes to assess body and visceral fat levels. They will also be followed for 10 days to assess sleep parameters through actimetry and sleep diaries

4
  • LUANA PRISCILLA OLIVEIRA DUARTE
  • Análise comparativa do ciclo sono-vigília, qualidade de sono e sonolência diurna em docentes da educação pública em nível de ensino básico e superior

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • JOHN FONTENELE ARAUJO
  • FRIDA MARINA FISCHER
  • Data: 26-may-2021


  • Resumen Espectáculo
  • The work context of elementary and higher education teachers presents different conditions, which may cause irregularities in sleep-wake pattern, excessive daytime sleepiness, and poor sleep quality. In this study, we compared the characteristics of work context, sleep knowledge and habits, sleep-wake cycle pattern, sleep quality and daytime sleepiness among 118 elementary school (BS) and 77 higher education (HE) teachers in public education. Participants completed the “Health and Sleep” and the Morningness and Eveningness (MEQ) Questionnaires, Pittsburg Sleep Quality Index, Epworth Sleepiness Scale and Sleep Diary for 10 days. Most of the ES teachers work 2 shifts (morning and afternoon), while in the EB, 1 to 2 shifts prevail, distributed among morning (21.6%), morning and afternoon (26.2%) and afternoon (24.3%); with a predominant weekly workload between 20-40h, being higher in the ES (t =-2.95; p=0.004). The teachers did not differ in bedtimes (t=-1.06, p=0.28) and time in bed (t=0.15, p=0.87) on working days, but the EB got up earlier (t=-3.07, p=0.01) on working and free days (t=- 2.37, p=0.01). Regarding the level of knowledge, the ES presented higher percentages of correct answers on the importance and influence of light on sleep schedules, while the EB, on general aspects about sleep. The EB presented higher levels of daytime sleepiness (t=3.04; p<0.001), without differences in the quality of sleep, which was poor in both groups (t=0.40; p=0.69). Regardless of education level, female gender predicted worse sleep quality (B=1.16; p=0.03), while morning tendency predicted greater irregularities in bedtimes (B=1.07; p=0.04), less daytime sleepiness (B=-0.09; p<0.01) and better sleep quality (B=-0.07; p<0.01). There was a tendency for higher scores on sleep knowledge to predict lower social lag (B=-2.16; p=0.06). Regarding the work context, starting work later predicted greater irregularity in time in bed (B=0.12; p=0.03), while finishing work earlier predicted greater irregularity in getting up times (B=-0.13; p<0.01) and time in bed (B=-0.15; p=0.01). Higher weekly workload predicted greater irregularity in getting up times (B=2.27; p<0.01) and time in bed (B=2.26; p=0.01); and higher number of shifts predicted greater social lag (B=13.66; p<0.01). Therefore, sleep parameters, daytime sleepiness levels and sleep quality of teachers are predicted by biological factors, such as sex and chronotype, and factors related to the work context, such as work schedules, weekly workload, and number of shifts, regardless of educational level.

5
  • EMANUEL LINEGLEY RIBEIRO DA SILVA JÚNIOR
  • RELAÇÃO ENTRE CRONOTIPO E O CICLO SONO-VIGÍLIA, SONOLÊNCIA DIURNA E ATENÇÃO EM ADOLESCENTES DO TURNO MATUTINO

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • FABIANA BARBOSA GONCALVES
  • SOFIA ISABEL RIBEIRO PEREIRA
  • Data: 28-may-2021


  • Resumen Espectáculo
  • One of the most remarkable characteristics in adolescents is the phase delay in the sleep-wake cycle, which can lead to changes in the chronotype, which starts to present a tendency to eveningness. This tendency to eveningness when confronted with school starts time can lead to a reduction in sleep time, social lag, diurnal sleepiness, which in turn can lead to worse cognitive and academic performance. Therefore, this study aimed to assess the relationship between the chronotype and the sleep-wake cycle (SWC), diurnal sleepiness and attention in adolescents in the morning shift of schools in Natal. 207 adolescents of high school (age: 15.71 ± 1.3 years; 133 girls) participated in the study. The participants answered the questionnaires: “Health and Sleep”, the Food Consumption Questionnaire, the Sleep Diary for 10 days, which contained the Maldonado Sleepiness Scale. The midsleep on free days sleep corrected (MFSc), used as chronotype indicator and basis for calculating social lag were calculated from the data of the sleep diary. Attention was assessed by the Continuous Performance Task, between 7:30 AM and 9:30 AM during school days with a single application. In general, the sample had times to go to bed and get up earlier, less time in bed and more sleepiness on awaking during the week (Anova, p <0.0001). In relation to the chronotype, the evening types go to bed and wake up later, regardless of the day of the week, with higher irregularity in bedtime and waking times, and higher level of Social Lag (Anova - Sidak, p <0.0001). On the other hand, morning types had more time in bed at the weekend and more irregular time in bed (Anova - Sidak, p <0.01). Regarding attention, the longer time in bed at the night before the task predicted a higher percentage of correct responses for phasic alertness (β = 0.038, p <0.01). However, a greater tendency to eveningness predicted a higher percentage of correct responses in the tonic alertness (β = 0.022, p <0.01), selective attention (β = 0.009, p <0.01) and phasic alertness (β = 0.036, p <0.05), and a lower percentage of omissions in selective attention (β = -0.010, p <0.01). Although the chronotype was related to the sleep-wake cycle and attention cycle in adolescents, further studies are needed to investigate the relationship between eveningness and attention.

6
  • LEONARDO HENRIQUE COIMBRA VIEIRA
  • Generosity in Soccer Fans: assay of a typological instrument

  • Líder : MARIA EMILIA YAMAMOTO
  • MIEMBROS DE LA BANCA :
  • DENNIS WAYNE WERNER
  • FIVIA DE ARAUJO LOPES
  • MARIA EMILIA YAMAMOTO
  • Data: 28-may-2021


  • Resumen Espectáculo
  • Violence associated with soccer, or hooliganism, is a global phenomenon that causes upheavals in society. The view that football fans could be divided into types brings new possibilities for research about the evolutionary perspective on cooperative group dynamics through social dilemmas. Parochial altruism, understood as an association between group bias and antagonism to other groups, is the relevant representative of this dynamic, and its investigation through economic games can be done by measuring the generosity of individuals. However, methodological disregard for the costs inherent in cooperation can make the results less representative of the intensity of affiliation to a group, and hence of the motivations behind parochial altruism. In addition, the relationship between cooperative conflict and cognition suggests that physiological variables can influence how individuals deal with social dilemmas. Thus, by hypothesizing, that different types of supporters differ in degree of cooperative motivation. This project will investigate the pertinence of the division of the population in types, and differences in the generosity and neuroendocrine profile of the fans. To this end, parochial behavior will be attributed to the adoption of the paradigm of effort-based decision-making, in order to faithfully represent the fans' affiliative intensity.

7
  • THAÍS AGUES BARBOSA
  • Fantastic genes and where to find them: molecular basis of alcohol effects in zebrafish populations

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • DENIS BROOCK ROSEMBERG
  • ROSANE SOUZA DA SILVA
  • Data: 11-jun-2021


  • Resumen Espectáculo
  • Alcohol (or ethanol) is a powerful psychoactive substance and its excessive consumption may lead one to develop alcoholism. However, it's known that genetic, physiological, and behavioral variations influence how individuals respond to alcohol. In this sense, comparative studies among populations from the same species are useful. Thus, we evaluated behavioral and genetic variations in response to alcohol among zebrafish populations (Danio rerio), using different protocols and stages of development. In the first chapter, we induced alcohol dependency in three zebrafish populations (AB, TU, and WT) using chronic alcohol exposure protocol. We analyzed locomotor and anxiety-like behavior and the expression of target genes involved in neurotransmitter metabolism. We observed that locomotor response and associated genes were similar within all populations. Regarding anxiety, both AB and TU fish presented robust responses, while WT didn't show alterations. In the second chapter, we exposed zebrafish embryos to alcohol from the three populations, in order to simulate the fetal alcohol spectrum disorder - FASD. We evaluated behavior in three ontogenetic phases: larval, juvenile, and adult. We verified, again, consistent and patter response between AB and TU fish, while WT showed no response. In the last chapter, we tried to establish a new protocol of voluntary search for alcohol using a two-chamber apparatus with no mix of substances. After inducing fish to alcoholism throughout chronic alcohol exposure, we tested their preference for alcohol or water. We observed that animals preferred the water side, evidencing that perhaps the protocol wasn't sufficient to induce seeking behavior. In general terms, alcohol response depends on the exposure regimen to the drug and the genetic background contribution. For translational studies, standard populations commonly used in laboratories offer reliable and reproducible results, thus, they should be prioritized.

8
  • DÉBORA LOUISE DA CRUZ SILVA
  • Should I call or should I hold? Factors affecting food-associated calls in wild Callithrix jacchus

  • Líder : ARRILTON ARAUJO DE SOUZA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • MARIA EMILIA YAMAMOTO
  • JUDITH BURKART
  • MARIA ADELIA BORSTELMANN DE OLIVEIRA
  • Data: 21-jun-2021


  • Resumen Espectáculo
  • Food-associated calls are widespread among primates. Its main function is to attract conspecifics to food sources, and callers may benefit from an increase in their inclusive fitness and by diluting predation risks. Conversely, food calls may increase competition over resources. In cooperative breeders, these calls may indicate their high proactivity in sharing resources with other group members, especially at moments where infant care is necessary. In the absence of infants, individuals possibly adopt compensatory strategies to offset infant care costs and to increase energy intake. We aimed at investigating Callithrix jacchus vocal behavior in feeding contexts, jointly addressing their cooperative care and intragroup competition. Thus, we performed a series of experiments in which marmosets would encounter food with diverse quantity and quality, both in periods where infants were present and not. We evaluated the latency to call, time feeding before calling, and the number of calls emitted before others’ arrival by the first animal to find the food. Finally, we analyzed the effects that marmosets’ social status, presence of infants, and different experimental conditions had on these behavioral variables. We observed greater participation of helpers in all sessions. Male helpers, in the presence of infants, had a faster vocal response, decreased food consumption, and an increased food call production. In the absence of infants, however, opposite results were found. Corroborating greater proactivity and willingness to share when infant care is necessary. Regarding different experimental conditions, female helpers showed an increase in their calling latency and food consumption for small amounts of food, which may indicate a lower propensity to share limited resources. Whereas males exhibited a decrease in latency and food consumption only for high-quality resources. Our results are consistent with Callithrix jacchus social dynamics and reinforce male helpers’ proactive prosociality and their crucial role in infant care, whereas subordinate females engage in a more competitive and less cooperative behavioral profile.

9
  • LUCAS SANTOS ALVES
  • Interactions between atmospheric variables, the polymorphism of the VNTR of the gene PER3 and sleep parameters of adult young people living in different latitudes

  • Líder : MARIO ANDRE LEOCADIO MIGUEL
  • MIEMBROS DE LA BANCA :
  • LEANDRO LOURENÇÃO DUARTE
  • MARIO ANDRE LEOCADIO MIGUEL
  • SEBASTIAO PACHECO DUQUE NETO
  • Data: 30-jul-2021


  • Resumen Espectáculo
  • Introduction: The PER3 VNTR polymorphism is an individual variability present in human and non-human primates that is functionally associated with sleep and circadian phenotype. Furthermore, the latitude where the subjects reside seems to be an important factor for synchronization, both photic and social, even more when we consider that we are increasingly deregulating sleep schedules due to demands at work, school or other factors. Considering that the concept of latitude reflects a set of characteristics that involve geophysical and climatic factors, it also seems to be related to sleep markers, such as daytime sleepiness. Objective: Thus, the objective of this work is to verify which interactions exist between the VNTR polymorphism of the PER3 gene and latitude-specific environmental markers in sleep parameters of young adults living in three different latitudes of the Brazilian territory. Method: The method used consisted of three stages, with Stage 1 referring to the use of the sociodemographic questionnaire, the Munich chronotype and the excessive daytime sleepiness scale. In step 2, the genotyping of cells from the oral mucosa was carried out via DNA extraction and classification of the subjects according to the VNTR polymorphism of the PER3 gene. The last step consisted of collecting variables related to latitude in three different cities with different latitudes: Maceió – AL, Campinas – SP and Porto Alegre – RS. The sample number was 702 participants, including only undergraduates who start classes between 07:30-08:00 in the morning. Subjects using medications that affect sleep and who had traveled across the country in the month prior to selection were excluded. After descriptive statistics, the Kruskal-Wallis (p-value <0.05 adopted for significance) was used as a basic test of inferential statistics. Results and discussion: We determined that young adults residing in high latitudes, compared to those living in low latitudes, have higher levels of social jet-lag, excessive daytime sleepiness and are more afternoon. Furthermore, the longest twilight durations, the longest photophase length, the greatest phase angle differences and the lowest mean solar irradiance were found in Porto Alegre, in absolute contrast to the findings in Maceió. Regarding the VNTR polymorphism of the PER3 gene, residents of Porto Alegre and with 4/4 polymorphism showed a sleep compensation on weekends, given the accumulated sleep deprivation during the week. Conclusions: This work provides us with details of sleep behavior and the synchronization process in young Brazilian adults living in different latitudes, representing geophysical and social particularities. Our findings may contribute to the understanding of genetic-behavioral and environmental factors that may explain the existence of high variability in health-disease processes. 

10
  • JAMILE LIMA CARVALHO
  • PERCEPTION OF FEMALE BODY HAIR: AN EVOLUTIONARY ANALYSIS

  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • FIVIA DE ARAUJO LOPES
  • JAROSLAVA VARELLA VALENTOVA
  • Data: 03-ago-2021


  • Resumen Espectáculo
  • Depilation, removal or reduction practices by the body have been present in our history since the times of the Ancient Age, in different human cultures, inside and outside Western industrial societies. Despite being behaviors performed by men and women, hair reduction and removal is still, in terms of frequency, more practiced by women and signified differently between the sexes, whether within gender constructs or in social and sexual contexts. In this sense, evolutionary hypotheses have been launched in order to understand the role of the removal of body hair, as well as the intersexual difference: what makes the 'hairless' ideal an especially feminine attractiveness norm and that, in adaptive terms, preference and display of a hairless body could mean within sexual selection in humans. The aim of this study was to investigate the perception of individual characteristics of women in conditions with and without body hair and as possible within a context of attractiveness and choice of partners. Photos of female models with and without hair on the legs and armpits were used and, through online questionnaires, participants provided their first impressions of the age, personality traits (Big 5) and sociosexuality of the women observed. As a result, we found that men and women regarded as furry models as being more extroverted and more open than as furless models. Only female participants perceived models with body hair as being more emotionally stable. Only male participants perceived hairless models as more amiable and as models with body hair as being more sociosexually unrestrained. No difference was found for age and consciousness between the groups with and without body hair for both sexes. The present work aimed to expand the scientific knowledge about the subject, as well as to deepen the discussion of subjects with high social interest. It is hoped that the results of this study allow us to bring important contributions to the feminist debate and provoke reflections on the construction of gender and attractiveness norms.

11
  • NATHALIA EVELYN MARTINS LEITE
  • Influence of marital satisfaction and stress in women on in vitro fertilization treatment 

  • Líder : NICOLE LEITE GALVAO COELHO
  • MIEMBROS DE LA BANCA :
  • NICOLE LEITE GALVAO COELHO
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • ANAGLÓRIA PONTES
  • Data: 04-ago-2021


  • Resumen Espectáculo
  • One of the most commonly used assisted reproduction techniques today is in vitro fertilization (IVF), but an average worldwide success rate observed by this therapy is about 30%. Physiological and psychological aspects seem to contribute to the treatment outcome. Thus, this study analyzed how psychophysiological stress (assessed by Lipp's general stress, stress related to infertility and salivary cortisol awakening response – CAR) and marital satisfaction (assessed by dyadic adjustment, sexual satisfaction and attachment style) are related with the outcome of IVF, and whether any of these parameters predict treatment success. This was a cross-sectional study carried out at the Januário Cicco Maternity School of the Federal University of Rio Grande do Norte, throughout 2017, with 20 women in the first cycle of IVF. It was seen that the participants who were successful in the treatment, that is, who become pregnant, had greater dyadic cohesion, greater sexual satisfaction and lower CAR. Dyadic cohesion proved to be a predictor of success. A greater adjustment and dyadic consensus were related to the absence of general stress, with the dyadic consensus being a predictor of the absence of stress. In fact, most of the sample was free from psychological stress, and the women with acute stress levels were those with the preoccupied attachment style. These results highlight the importance of low cortisol levels and a good marital relationship for the success of IVF. Therefore,  strategies that helps patients to deal with stressor of treatment and marital relationship should be studied and implemented aiming increase the FIV success rates. It is also important highlight the necessity of further studies to better understand the relationship of these psychophysiological factors with the outcome of IVF in a larger sample, as well as to assess the profile of women seeking treatment in private clinics, which may vary from the profile found in this study of a population sample of lower socioeconomic status with treatment paid for by the Serviço Único de Saúde (SUS), Unified Health Service in English.

12
  • NATHALYA CHRISPIM LIMA
  • INVESTIGATION ON SLEEP DEPRIVATION AND EXECUTIVE FUNCTIONS IN PROGRAMMERS THROUGH SUBJECTIVE AND OBJECTIVE MEANS

  • Líder : KATIE MORAES DE ALMONDES
  • MIEMBROS DE LA BANCA :
  • KATIE MORAES DE ALMONDES
  • JOHN FONTENELE ARAUJO
  • IZA CRISTINA SALLES DE CASTRO
  • Data: 23-ago-2021


  • Resumen Espectáculo
  • Recent studies associate the prolonged and excessive use of new technologies, such as tablets, computers and smartphones, with sleep deprivation, with suggestions of negative impacts on quality and duration of sleep, and of morning consequences of impaired sleep, such as non-restorative sleep and daytime sleepiness. Most of those studies focus on younger age groups, such as children, adolescents and young adults, and mostly on the use of technology for leisure, with few considering the impact of excessive technology use on other age groups, especially on professionals who work directly and for long periods with said technologies, such as programmers, developers and software engineers. Among the long-term effects of this sleep deprivation, we can mention the impairments of cognitive functioning associated with reduced or poor quality of sleep: the most recent literature brings evidence of impairments to processes such as memory, attention and executive functions. Among those, research on the impact of sleep deprivation on executive functions stands out for its conflicting results, with losses in simpler tasks contrasting with the maintenance of executive functioning in cognitively more complex tasks. Processes such as inhibitory control, cognitive flexibility and working memory, classified as executive functions, are of great importance for the individual's functionality in different spheres of life, from daily activities to job performance, suggesting the importance of further research regarding the effects of sleep deprivation on these functions. In view of these three factors - sleep deprivation, excessive use of technology and impairment of executive functions, this study aims to investigate sleep deprivation and potential impacts on executive functions in a population of adult programmers, using subjective methods (neuropsychological tests) and objective methods (P300 wave analysis), compared to a control group without sleep deprivation symptoms and who does not use information technology for work.

13
  • NATÁLIA BRITA DEPIERI
  • Caracerization of activity-rest cycle, light exposition and sleep quality in blind subjects.

  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • FELIPE BEIJAMINI
  • JOHN FONTENELE ARAUJO
  • MARIO ANDRE LEOCADIO MIGUEL
  • Data: 30-ago-2021


  • Resumen Espectáculo
  • It is estimated that 50% of blind people who do not perceive light consciously are unable to synchronize with the 24-hour day. Since non-photic time lanes would not be sufficient to synchronize individuals with vision loss. Considering that the studies that characterized this population were carried out in the northern hemisphere in places with high latitude and consequent wide seasonal variation, the objective of this study was to characterize the pace of activity and rest, the rhythm of exposure to light and sleep quality of the blind in the city of Natal - RN - Brazil, which is located at a low latitude, near the equator, with little seasonal variation. For this, we used actimetry to characterize circadian rhythm, and questionnaires to characterize the chronotype, daytime sleepiness, sleep quality, insomnia, risk of obstructive sleep apnea, as well as questions related to the perception of light and time. The sample consisted of 22 blind people who answered the questionnaires and among them 14 used the actimeter for approximately 20 days. Therefore, we observed that unlike that classically found in the literature, no participant was in free course, both by actimetry and by the results of the questionnaires, which indicate that they do not have severe sleep-related problems. Thus, we verified four factors that can explain the adjustment of this sample with the 24-hour day, which are: environmental (temperature and luminosity), social (regular working and study times and daily interaction with other people), physical activity and use of electronic devices (especially mobile devices). We verified that the main differential of this work with the other ones already performed with non-photic synchronizers is that currently the entire population has easy access to the cell phone. That in the case of the blind is a tool used at all times, which facilitates their routine, especially mobility and communication. However, this cell phone is also helping the adjustment of these blind people, since it is a means of constant temporal information. 

14
  • SOFIA CORADINI SCHIRMER
  • Neotropical butterflies melanism pattern

  • Líder : DANIEL MARQUES DE ALMEIDA PESSOA
  • MIEMBROS DE LA BANCA :
  • ANDROS TAROUCO GIANUCA
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • VINÍCIUS DE AVELAR SÃO PEDRO
  • Data: 08-sep-2021


  • Resumen Espectáculo
  • Patterns of brightness and coloration of butterfly wings may have intraspecific, interspecific and physiological roles, with one of the main functions being thermoregulation. Differences in brightness between the ventral and dorsal surfaces serve to capture and dissipate heat, as butterflies regulate exposure to heat sources by opening and closing wings. Melanism can vary among butterfly families, different wing faces, and be related to wing size and environmental factors. Although well-established patterns exist for other biogeographic regions, no studies have evaluated these issues for Neotropical butterflies. The two main objectives of this work were (1) to survey the scientific production on butterfly color patterns on a global scale, to identify the main knowledge and geographic research gaps; and (2) to evaluate which environmental factors are related to neotropical butterfly wing melanism. The production of papers on butterfly coloration increased and followed the overall scientific production rate (r = 0.076, p > 0.05). We note the concentration of published articles in English-speaking countries (~60%), with most studies having American first authors (27.8%). We found that smaller butterflies are lighter (p < 0.05) and that families vary in brightness differences between the dorsal and ventral faces. There was no relationship between environmental variables and brightness pattern for Neotropical butterflies (p > 0.05), and butterflies from different biomes show similar melanism patterns. Probably, other variables may influence the melanism pattern of these butterflies, such as solar irradiance. For warmer environments, it is advantageous for the butterfly to be small and bright, thus avoiding stresses due to overheating. This variation in brightness among families may be related to different thermal tolerance thresholds, as well as different anti-predatory strategies such as "dynamic flash". Nevertheless, it is necessary to include more species from other biomes and localities in the rest of the country to re-evaluate our hypotheses based on more extensive environmental gradients, given that much of the research focusing on coloration and brightness patterns of butterflies evaluates communities from the northern hemisphere.


15
  • STEFANIE DA PAZ FIGUEIREDO DE MACEDO
  • The relationship between chronotype, social jetlag, quality of sleep, diurnal sleepiness, depression and anxiety in students of health-related undergraduate courses of UFRN


  • Líder : MARIO ANDRE LEOCADIO MIGUEL
  • MIEMBROS DE LA BANCA :
  • DENISE MORAIS LOPES GALENO
  • LEANDRO LOURENÇÃO DUARTE
  • MARIO ANDRE LEOCADIO MIGUEL
  • Data: 30-sep-2021


  • Resumen Espectáculo
  • In this project we proposed to understand the prevalence and relationship between sleep quality, chronotype, social jet lag, daytime sleepiness and the indications of depression and anxiety disorders in young university adults.  Our sample is composed of 578 students, of which 372 (64.36%) are women and 206 (35.64%) are men, from health courses at the Federal University of Rio Grande do Norte, aged between 18 and 32 years. To this end, we applied the following questionnaires: Munich Chronotype Questionnaire (MCTQ), Horne and Östberg's Morningness-Vespertiness Questionnaire (MEQ), Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Beck's Depression Inventory (BDI), and the Beck Anxiety Inventory (BAI). In our results we extracted information for calculating social jet lag from the MCTQ, and from the MEQ results we observed that most of our sample is composed of intermediate chronotype individuals. In addition, we demonstrated that most participants suffer from substandard sleep quality and excessive daytime sleepiness; for depression and anxiety the values with the highest frequency indicate minimal presence of symptoms or absence of these disorders in the students. As a result of Spearman correlations we found between Munich- MEQ (rho= 0.595; p<0.001); Munich- Social Jet-lag (rho= 0.543; p<0.001); Social Jet-lag- MEQ (rho= 0.456; p<0.001); PSQI- BDI (rho= 0.303; p<0.001); PSQI- BAI (rho= 0.452; p<0.001); PSQI- ESS (rho= 0.312; p<0.001) and BAI-BDI (rho= 0.356; p<0.001). These results suggest that there is an association between social jet lag and chronotype, with the restriction-expansion effect between classes days and free days being greater in individuals of the evening chronotype. Among the most significant findings we identified a moderate relationship between anxiety and sleep quality.  Furthermore, we identified that there is a relationship between worse sleep quality and symptoms of depression, anxiety, and excessive daytime sleepiness. Finally we identify that depression symptoms are moderately related to anxiety. Thus, we conclude that the high load of classes and studies, as well as the very early class start time among young health college adults, are factors that contribute to increased stress, poorer sleep quality, decreased academic performance, daytime sleepiness, and the emergence of anxiety and depression symptoms, whose women and evening students are the most vulnerable individuals to these disorders. Therefore, this issue deserves more attention from the scientific community and public health agencies so that measures can be adopted in favor of these students.

16
  • MARIA LARA PORPINO DE MEIROZ GRILO
  • DOES AYAHUASCA MODULATE RESILIENCE? AN EVALUATION IN PRIMATE MODEL OF MAJOR DEPRESSION

  • Líder : NICOLE LEITE GALVAO COELHO
  • MIEMBROS DE LA BANCA :
  • BRUNO LOBAO SOARES
  • JAIME EDUARDO CECILIO HALLAK
  • NICOLE LEITE GALVAO COELHO
  • Data: 08-oct-2021


  • Resumen Espectáculo
  • Throughout evolution, the animals have experienced various stress situations, so there is a great variability of stress responses, some adaptive and others not. Major depression (MD) is a psychopathology associated with chronic stress, vulnerability phenotypes, and non-adaptive stress responses. MD is one of the most disabling psychopathologies in the world, and there is still no completely effective treatment for it, thus generating enormous individual, social and economic losses. Thus, using as a basis the theory of stress inoculation which postulates that resilience can be trained, the psychedelics have become the target of research with prophylactic schemes against the emergence of some mental diseases. Ayahuasca (AYA) is a traditional beverage from the Amazon Forest that acts on the serotonergic system, and in addition to psychedelic effects has antidepressant action. Considering that from an economic, social and psychological point of view, treating depression is more expensive than preventing it, this study has evaluated the possible prophylactic effects of prolonged use of ayahuasca against a major depression induction protocol, the social isolation (9 weeks), using a nonhuman primate animal model of depression, C. jacchus. For this, physiological (fecal cortisol) and behavioral evaluations were performed. The animals (19 juvenile males) were divided into 3 groups: Ayahuasca Group (AG), 6 animals received 3-times AYA dosing while undergoing the depression inducing protocol; Stressed Group (SG) 8 animals submitted to the depression inducing protocol without going through the prophylactic scheme; and Family Group (FG), 5 control animals that remained in their families without any experimental scheme. Overall, a more adaptive stress response to AG was observed when compared to SG. The animals treated with AYA showed a fecal cortisol reactivity like FG and higher than EG, therefore they did not present hypocortisolemia, which is frequently induced by this depression-inducing protocol. Also, AG did not show signs of anhedonia and increased behavior indicative of chronic stress, for example: scratching, scent marking and autogrooming, which, on the other hand, were expressed by SG. Thus, the results showed a prophylactic action of AYA in response to a depression inducing protocol, this substance promoted the expression of resilience responses, keeping the response of cortisol in its homeostatic levels and buffered the emergence of depressive phenotypes. Although new studies are needed, this work opens doors to a new type of intervention in mental health field, the prophylactic use of psychedelics to prevent psychopathologies associated to chronic stress.

17
  • RAIANE DOS SANTOS GUIDI
  • Living with strangers: effect of personality on the social management of captive capuchin monkeys (Sapajus libidinosus)

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • BRISEIDA DOGO DE RESENDE
  • RENATA GONCALVES FERREIRA
  • Data: 29-oct-2021


  • Resumen Espectáculo
  • Group life requires investment of time and energy to maintain relationships between individuals. Factors such as sex, age and rank influence the relationship between individuals, recently the influence of personality on relationships in non-human animal societies is investigated. Capuchin monkeys have a tolerant matrilineal social structure, with a rich social repertoire and a high cognitive capacity. These characteristics make them excellent models for translational studies. In Brazil, capuchin monkeys are intensely trafficked and the continuous influx of individuals in rehabilitation centers (CETAS) poses challenges for the formation of social groups. In the present work we analyze the influence of personality on the management and social relationships of captive-raised capuchin monkeys, at individual, dyadic and group levels. We hypothesized that: 1) we would find personality axes similar to those already described in the literature for capuchin monkeys; 2) the axes of openness and agreeableness would influence social play and grooming behaviors, respectively; 3) the departure of individuals from their social groups would be affected by their personalities and 4) that at the time of insertion, individuals would present a behavioral strategy for social acceptance related to their personality. During 1 year and a half (369.25 hours) we followed 41 individuals and 88 formations of social groups. ICC analysis of scores attributed to animals through the Hominoid Questionary Personality indicates agreement in 47 adjectives and factorial analyzes indicate 5 personality axes: Assertiveness, openness, agreeableness, confidence and neuroticism. Generalized linear models selected via the akaike criterion indicate that the five personality axes and the Euclidean distance between the dyads influenced grooming and play behaviors, but more but individuals with higher score in openness and agreeableness present different affiliation strategies within the group, where individuals with higher score in openness playing more and individuals with higher score in agreeableness grooming more. We also detected that individuals with higher scores in assertiveness and neuroticism are more removed from their social groups and the opposite occurs for individuals with high scores in agreeableness and confidence. In addition, individuals exhibit sexual display and request grooming as a strategy for the acceptance and tension-reducing at the time of social insertion, with individuals who score high on confidence showing less sexual display. Our results indicate that personality influences relationships and management. And that it can be another tool to help management decisions and provide better well-being to captive individuals.

Tesis
1
  • DANIELE OLIVEIRA SOUZA
  • Effect of Lippia alba essential oil on neuropathy caused by sciatic nerve constriction in rats
  • Líder : EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • MIEMBROS DE LA BANCA :
  • EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • FERNANDO VAGNER LOBO LADD
  • RENATA FIGUEIREDO ANOMAL
  • FRANCISCO WALBER FERREIRA DA SILVA
  • JOSÉ HENRIQUE LEAL CARDOSO
  • Data: 05-mar-2021


  • Resumen Espectáculo
  • Peripheral nerve injuries are a public health problem. Motor, sensory, autonomic deficits and the development of Neuropathic Pain (DN), resulting from peripheral nerve injuries, can compromise patients' quality of life. After nerve damage, oxidative stress occurs and the release of inflammatory cytokines and allogeneic mediators that induce DR. The occurrence of these problems instigates the search in nature for compounds for the manipulation of new drugs. Lippia alba is a medicinal plant whose essential leaf oil has biological activity in the Peripheral Nervous System (SNP). The aim of this study is to evaluate the effect of treatment with Lippia alba essential oil (OELa) on peripheral neuropathy caused by Chronic Sciatic Nerve Constriction (CCNC) in rats. Thirty Rattus novergicus (Wistar) rats, of both sexes, with body mass varying between 200-250g were used. The animals were divided into the experimental groups: Control treated vehicle (CON), control treated with OELa 100 mg/Kg, p.o. (CON+OELa), group submitted to CCNC treated with vehicle solution (CCNC) and group submitted to CCNC treated with OELa 100 mg/Kg (CCNC+ OELa). The treatment was administered 30 minutes before the CCNC was performed on the animal's right sciatic nerve for 14 consecutive days. The pain hypersensitivity test was performed using the von Frey test and hot plate, 24 hours before CCNC induction (day 0), and on days 5, 7, 9 and 14 after CCNC. On the 14th day after CCNC, the animals were euthanized. Then, dissection of the right and left sciatic nerve was performed to analyze the extracellular record of the Compound Action Potential (PAC). The evaluated parameters of the PAC were: Pico-a-Pico Amplitude (APP), chronaxia, positive amplitude reobase, conduction speed and duration of the 1st and 2nd components of the PAC. The phytochemical analysis of OELa identified a quantitative variation of substances, the major compound of which was citral (geranial with 42.59% and neral with 28.21%). The evaluation of the mechanical sensitivity presented in the CON an average of 20.87s in the reaction time to the stimulus. In the CCNC group, there was an increase of 72.4% in the reaction time to the stimulus on the 5th evaluation day in relation to the CON, followed by a “sustained” reduction from the 7th evaluation day, in 54.65%, 59.34%, 58.8% on evaluation days 7, 9 and 14, respectively in relation to the CON, characterizing mechanical hyperalgesia. The CCNC + OELa group increased the reaction time to mechanical stimulus by 116.79%, 145.4%, 54.56% and 62% on evaluation days 5, 7, 9 and 14, respectively in relation to the CON. In the CON + OELa group, the reaction time to the stimulus increased by 141.2% after the 5th evaluation, showing a greater response on the 7th evaluation day, with an increase of 260%. There was no significant difference in the sensitivity of the thermal stimulus in rats submitted to CCNC and CON group. However, there was a 56.25% increase in reaction time to the stimulus in the CON + OELa group also on the 7th evaluation day, compared to the CON. In the other experimental groups, there was no significant difference. CCNC caused electrophysiological changes in all evaluated parameters. The sciatic nerve excitability in the CCNC group (mean: 2.5 ± 0.14) increased by 27.53%, when reducing the reobase, compared to the CON (mean: 3.38 ± 0.17). Meanwhile, the chronaxia value increased by 54.89% in the CCNC group (76.67 ± 7.4) compared to the CON (49.5 ± 0.34). In the CCNC+OELa group (3.6 ± 0.05), the reobase increased by 39.5%, compared to the CCNC group, the chronaxia (59.7 ± 1.12) in this group did not change. The reobase in the CON + OELa group (4.14 ± 0.18) differed by 16.5% in relation to the CON. In the NE CCNC group (3.15 ± 0.25) the reobase was not changed. The chronaxia for the CON + OELa (68.5 ± 2.7) and NE CCNC (65.2 ± 5.7) groups did not differ from the CON. The APP in the CCNC group decreased 51.62% in relation to the CON. When associated to treatment with OELa (CCNC + OELa) the reduction in APP was 73%. The CON + OELa group reduced the APP by 54.8% compared to the CON. The positive amplitude of the first component in the CCNC group decreased by 52.53% in relation to the CON. In the CCNC + OELa group, it decreased 74.59%. The CON + OELa group also showed a 57% reduction. The second component was not registered in the CCNC group. However, this was preserved when CCNC was associated with treatment with OELa (CCNC + OELa), with an average of 0.3 ± 0.03, n = 6, with a decrease in amplitude of 88.14% in relation to the CON. The CON + OELa group also decreased the amplitude of the second component by 34.78%, with an average of 1.65 ± 0.14, n = 8, in relation to the CON. The NE CCNC group (2.24 ± 010, n = 6) showed no change compared to the CON. Regarding the PAC's conduction speed, the CCNC group showed a 44.73% reduction in the first component of the PAC. Treatment with OELa (CCNC + OELa) reversed this decrease by 102.96%, compared to the CCNC group. The other experimental groups showed no statistical difference, presenting the following averages: CON + OELa: 92.36 ± 5.28, n = 7; NE CCNC: 112.1 ± 14.45, n = 6. In the second component of the PAC, the driving speed was not changed in the CCNC + OELa and CON + OELa groups compared to the CON. The duration of the first component of the PAC increased by 45.21% in the group submitted to CCNC, in relation to the CON. The other groups showed no significant difference compared to the CON. As for the duration of the second component of the PAC, in the CCNC group it was not possible to evaluate, since it was not registered. In the other experimental groups, there was no statistical difference in relation to the CON. PAC behavioral and electrophysiological assessment data show that they are in line, suggesting an anesthetic effect of OELa. Since in the sensitivity assessment there was an increase in the response time to the stimulus and an increase in the reobase in the groups that received treatment with OELa, while in the CCNC group these parameters decreased. However, in the CCNC group, the chronaxia was increased, possibly related to changes in the passive properties of the membrane, resulting from CCNC. It is important to note that there was no change in chronaxia in the groups treated with OELa, suggesting a neuroprotective effect of OELa through neuronal damage, probably due to its antioxidant activity. Another evidence of the neuroprotective effect of OELa is the preservation of the fibers of the second component of the PAC in the CCNC + OELa group, considering that in the CCNC group there was no record of this. This is an important fact, as this phenomenon is probably related to the reduction of neuroinflammation and neuronal damage.

2
  • NATALIA ANDREA CRACIUN BOCCARDI
  • Investigating the relationship between prosociality and socioeconomic status in children
  • Líder : MARIA EMILIA YAMAMOTO
  • MIEMBROS DE LA BANCA :
  • MARIA EMILIA YAMAMOTO
  • FIVIA DE ARAUJO LOPES
  • DANDARA DE OLIVEIRA RAMOS
  • ANUSKA IRENE DE ALENCAR
  • PATRICIA IZAR
  • Data: 26-mar-2021


  • Resumen Espectáculo
  • There is an ongoing effort by researchers to understand what are the universal factors that favor prosociality in its various forms. One of these factors is the socioeconomic status (status). Evidence about the relationship between status and prosociality is controversial both in children and adults. The present thesis investigates this association in children using different methods. The first chapter provides a general introduction. The second chapter offers a theoretical review of the evolution of social hierarchies and the influence of the class on pro-sociality. The following three chapters are empirical papers, developed from three databases collected in 2012-2013 and 2018-2019. In the third chapter, we took a step back and checked whether economic games have inter-situational and external validity. For this, we conducted the Public Goods Game, the Dictator Game, self-report scales and made behavioral observations. The results indicate that it is necessary to be cautious before inferring any prosocial phenotype to the individual from the outcomes of the games. The fourth chapter brings the status stratification. Through three studies, we assessed the association between different status measures and social contexts. The results showed that these two variables moderated the class differentiation, suggesting that it is not a simple and universal association. The fifth chapter focuses on a single criterion of individual status: parental education. Through two studies we suggest that parental education and children's prosociality are also associated in a complex way. In general, the empirical studies contribute to the discussion about prosociality in children and indicate that people from different classes do not necessarily have different prosocial preferences, but vary according to the behavior being investigated, the context involved and the adopted status criteria. As far as we know, these are the first Brazilian studies to investigate the association between children's status and prosociality through multi-methods. Finally, the sixth chapter summarizes some collaboration and extension activities carried out throughout the doctorate.
3
  • ANA CECÍLIA DE MENEZES GALVÃO
  • INVESTIGATION OF POTENTIAL BIOMARKERS OF MAJOR DEPRESSION
  • Líder : NICOLE LEITE GALVAO COELHO
  • MIEMBROS DE LA BANCA :
  • CRISTIANE VON WERNE BAES
  • FLAVIO FREITAS BARBOSA
  • LUIS FERNANDO FARAH DE TOFOLI
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • NICOLE LEITE GALVAO COELHO
  • Data: 07-abr-2021


  • Resumen Espectáculo
  • The understanding of pathophysiology of mental diseases is mandatory for the strengthening of precision psychiatry, since it can helps in prognosis, diagnosis, treatment, and monitoring of patients. In this context, the use of molecular biomarkers and sleep quality as tools seems to be promising. Among psychiatric illnesses, the mood disorders, especially major depression (MDD), have gained attention by the scientific community due to their increasing prevalence and morbidity. Initially, this study evaluated the sleep quality (Pittsburgh Sleep Quality Inventory: PSQI) and the levels of different peripheral molecules, such as: plasma C-reactive protein (CRP), the neurotrophic factor derived from the mature brain (mBDNF), serum cortisol (SC) and response to salivary cortisol (CAR), for compare them between a group of patients with major depressive disorder (n = 58) and a control group of healthy volunteers (n = 62). While patients in the first episode (de novo) (MD n = 30) had significantly higher CAR and SC levels than controls (n = 32), they showed similar mBDNF concentrations. Patients with treatment-resistant depression (TRD n = 28) had significantly lower levels of SC and CAR, and higher concentrations of mBDNF and PCR than controls (n = 30). Still, the severity of depressive symptoms and the poorest quality of sleep were negatively correlated with SC and CAR, and positively for mBDNF. Then, we evaluated the potential of these variables as biomarkers of MDD diagnosis and disease progression, for it we tested some multimodal mathematical models using multivariate logistic regressions and the RoC (Receiver Operating Characteristic Curve) curve. None of the tested diagnostic models had a higher accuracy than the Hamilton-6 depression rating scale (AUC = 0.99). The best model (AUC = 0.99) of disease progression included: PSQI, CAR, SC and mBDNF. In summary, these findings indicate that the type, intensity and direction of biological changes in MDD differ according to the progression of the disease. Moreover, the impact of these biological changes is mainly relevant for prediction of the progression of MDD, but not for its diagnosis. Thus, the present results help in the comprehension of pathophysiology of MDD and provide a foundation that can contribute to future studies that aimed at the development of mathematical models of MDD biomarkers that can be commercially available and used in the clinical practice of precision psychiatry.
4
  • VANESSA CARLA COELHO DE LIMA
  • Social Networks and Prosocial Behavior in Children

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • BRISEIDA DOGO DE RESENDE
  • FIVIA DE ARAUJO LOPES
  • MARIA ISABEL PATRICIO DE CARVALHO PEDROSA
  • RENATA GONCALVES FERREIRA
  • Data: 12-may-2021


  • Resumen Espectáculo
  • Prosocial behaviors are recognized as attributes essential to the formation and maintenance of bonds between individuals living in society. However, human social relations happen in a great number and in different ways, and the decision to act prosocially is influenced by proximal and contextual factors. In this work, we used social network analysis to examine the hypothesis that the prosocial behaviors of children 5-6 and 10-11 years old, are based on evaluations of contextual factors of the relationships between dyads and in the group as: social proximity and type of group. In a pilot study, 51 children (out of 170 predicted) had their social proximity and play networks constructed from a sampling effort of 25.5 hours of focal observation during the months of February to June 2018. They were also submitted to an application of the Dictator's Game, and four replicates of the Public Goods Game. Our results showed that: 1) the vertex degree of children of 5 and 6 years old was positively correlated with a higher offer of spontaneous pro-social behaviors, but the lower donation in the Dictator's game 2) The strength index was positively correlated the offering, and receipt of prosocial actions only among the youngest children; 3) For both ages, positive correlations were found between the offering of pro-social behaviors and the centrality of the individuals, as well as between the centrality and the reception of this type of behavior; 4) the reach correlated with the offering of prosocial behaviors at all ages. These results suggest that interactions between individuals and the position within their social networks relate to cooperative behavior and that socialization factors acquired with development seem to influence changes in the supply and reception of these behaviors. However, it is necessary to expand the sample to confirm our results.

5
  • DIVNA DJOKIC
  • Assessing song exchange between South American Humpback Whale (Megaptera novaeangliae) stocks

  • Líder : RENATA SANTORO DE SOUSA LIMA
  • MIEMBROS DE LA BANCA :
  • OLIVER ADAM
  • ELLEN GARLAND
  • KATHERINE PAYNE
  • ARTUR ANDRIOLO
  • RENATA SANTORO DE SOUSA LIMA
  • Data: 28-may-2021


  • Resumen Espectáculo
  • South America hosts two breeding stocks of humpback whales. During the austral winter/spring, stock A occupies the south-west Brazilian waters of the Atlantic and stock G, the south-east of the Pacific. Both stocks feed in high latitudes during the austral summer: Stock A in South Georgia and Sandwich Islands, and stock G in Corcovado Gulf, Magellan Strait and South Shetland islands. The aim was to determine if these stocks interact vocally and if so what is dynamics of song exchange that results in the evolution of song structure. Various researchers contributed to the dataset which is comprised by songs recorded in the breeding range of each stock, on their migration path and in feeding areas. Songs from years 2016 and 2017 were processed, while songs from 2018 and 2019 will further be included. Songs were transcribed into a sequence of letters representing each unit. Three criteria were used to letter-code each unit: the spectrogram, the aural perception by the analyst and the position of the unit in the recording. A string of letters was then generated. The Levenshtein distance between two strings computes the minimum number of insertions, deletions and substitutions necessary to transform one string into the other. Levenshtein calculation was applied on these letter strings resulting in values of similarity for further construction of a distance matrix. The matrix shows each song’s structure. Further, bird literature was consulted in order to establish new methods for assessing humpback whale song in more detail. Measurements widely applicable in bird song research were adapted to correspond a study of a humpback whale song: element repertoire (in humpback whale literature known as unit dictionary, (2) versatility (disposition of all units and their ratio within the recording), (3) syntax consistency (placement of units), (4) total number of unit types, as the total number of units sung by each individual per song , (5) mean number of units per song and (6) plateau This new approach could help in identifying if song structure changes more on the breeding or on the feeding sites. Preliminary results suggest a high level of song evolution along the breeding season, especially for stock G. Lacking recordings from the Antarctica feeding region for 2016 and 2017 are preventing any inferences on song evolution during that period. Indirect conclusions can be driven from song comparison among breeding areas in consecutive seasons. It is noteworthy that this project lays on the biggest humpback whale bioacoustic research network formed so far in Latin America.

6
  • FERNANDA DA FONSECA FREITAS

  • Eating behavior and anxiety in young adult women: similar situations in different contexts.

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • PATRÍCIA DE FRAGAS HINNIG
  • FIVIA DE ARAUJO LOPES
  • RACHEL COÊLHO RIPARDO TEIXEIRA
  • SANCHA HELENA DE LIMA VALE
  • VICTOR KENJI MEDEIROS SHIRAMIZU
  • Data: 29-jul-2021


  • Resumen Espectáculo
  • Current life conditions can negatively affect mental health and cause changes dietary
    and eating behavior. It is important to underscore that anxiety and changes in eating
    pattern are also symptoms attributed to the luteal phase of the menstrual cycle. These
    situations that compromise emotional health are usually associated with a propensity to
    desiring and consuming ―tasty‖ foods with high levels of sugar, fat, and calories, as this
    eating pattern possibly interacts with the central reward pathways, causing a pleasant
    and comforting experience, regulating and reducing negative emotions. This present
    study to investigate anxiety and some eating behaviors in young adult women,
    considering the use of oral contraceptives, the presence of premenstrual symptoms and
    the COVID-19 pandemic. With the exception of emotional eating there was no
    influence of the use of oral contraceptives on the other variables. Differences were also
    identified in scores of anxiety, craving for sweet foods and emotional eating according
    to the presence of premental symptoms and, in general, the pandemic positively
    impacted the anxiety and eating behavior of the participants. In conclusion, this study
    provides new and important information about the complexity of factors involved in the
    etiology of anxiety and variations in eating behaviors, highlighting the importance of
    studying different environments and different contexts, as these can generate different
    responses in people to similar situations.

7
  • ALICE BARROS CÂMARA
  • BEHAVIORAL AND NEUROCHEMICAL EFFECTS OF NOCICEPTIN/ORPHANIN FQ RECEPTOR ACTIVATION IN THE SOCIAL DEFEAT STRESS IN MICE
  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ELAINE CRISTINA GAVIOLI
  • FABIANO PERES MENEZES
  • MARIO ANDRE LEOCADIO MIGUEL
  • JULIA JENSEN DIDONET
  • LISIANE DE SANTANA SOUZA
  • Data: 10-ago-2021


  • Resumen Espectáculo
  • Several receptors have been associated with depression. However, the role of the NOP receptor in depression is not widely recognized yet. It is known that the NOP receptor has wide expression in the nervous system and it has been observed that the activation of this receptor induces inhibitory effects, causing a reduction in the release of neurotransmitters and/or inhibition of neuronal firing, depending on the site (pre-or post-synaptic) in which it is expressed. Thus, this study aims to evaluate the possible behavioral and biochemical effects of the NOP receptor agonist RO65-6570 in mice subjected to the condition of social stress. Methods: Male Swiss mice were employed in this study. To evaluate the depressive behavior in animals, the open field test, social interaction test, and tail suspension test were used. In addition, blood and tissue samples were used to evaluate the oxidative stress in lipids and proteins. Results: The NOP agonist, Ro 65-6570 (1 mg/kg, IP), or the stress of social defeat reduced the exploitation rate in the open field test performed six days after the social defeat protocol. The stress of social defeat or treatment with the NOP agonist also reduced the number of animal surveys in the open field on the penultimate day of the social defeat protocol. The stress of social defeat and/or the NOP agonist increased the immobility time in the tail suspension test performed eight days after the social defeat protocol, as well as reduced the social interaction of the animals on the last day of the social defeat protocol. However, seven days after the end of the protocol, only the drug alone was able to affect the animals' interaction. Additionally, the NOP agonist (1 mg/kg, IP) increased the concentration of carbonylated proteins (carbonyl groups) in the hippocampus. The stress of social defeat and the NOP agonist, together, increased malondialdehyde in the animals' serum and prefrontal cortex, as well as increased the concentration of carbonyl groups in the prefrontal cortex. Finally, the drug alone was able to raise malondialdehyde in the serum. The stress of social defeat and the agonist NOP did not affect the distance traveled in open field test, the animals' weight, defecation, grooming, as well as the concentration of malondialdehyde in the hippocampus. Conclusion: The activation of NOP receptor signaling can facilitate the acquisition of sub-chronic depressive behavior in animals, suggested by some behavioral tests. NOP receptor activation and social defeat stress (together) may be related to lipid peroxidation in the blood and prefrontal cortex of animals, as well as protein oxidation in the prefrontal cortex. The drug by itself may also contribute to serum lipid peroxidation and protein oxidation in the mice's hippocampus. These findings indicate a chronic pro-depressive profile induced by the activation of NOP receptor signaling, sometimes regardless of the presence of the stressor (social defeat protocol).

8
  • ANTONIA LÍRIA FEITOSA NOGUEIRA ALVINO
  • SHIFT WORK, SLEEP AND WAKE CYCLE AND CIRCADIAN RHYTHM REST AND ACTIVITY OF NURSES FROM SAMU DO NATAL AND GRANDE NATAL

  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • JOHN FONTENELE ARAUJO
  • FABIANA BARBOSA GONCALVES
  • JANE CARLA DE SOUZA
  • FAUSTO PIERDONA GUZEN
  • MARIA FILOMENA CEOLIM
  • Data: 10-nov-2021


  • Resumen Espectáculo
  • Sleep is a physiological state that occurs cyclically in most species. Human beings, for example, spend more than a third of their lives sleeping. However, not all humans are able to dedicate that one third to sleep for several reasons. One of these reasons is the implementation of working in shifts and because of it, they are forced to reduce their total sleep time according to the demands of their job. This research aims to study the pattern of the sleep/wake cycles, their regulation mechanisms (homeostatic and circadian components), moods, and fatigue of nurses who are chronically submitted to shift work. METHODOLOGY: This is a cross-sectional study, with a quantitative approach and observational design, with thirteen evaluation measures, conducted with 47 nurses assigned to the “Serviço de Atendimento Móvel de Urgência - SAMU” (Mobile Emergency Service) in Natal and Greater Natal area. To know the sleep/wake cycle patterns, The Pittsburgh Sleep Quality Index (PSQI), the Sleep Habits Questionnaire, the Epworth Sleepiness Scale (ESS), and the Sleep Diary, will be used (as subjective measures) and actigraphy (L5, M10, IV and AR) and polysomnography (F3-F4, C3-C4, O1-O2, Ad-Ae, OCG, EMG, ECG, respiratory movements and SPO2) will be used as objective measures. The Horne and Ostberg’s Morningness-eveningness Questionnaire (MEQ) and the Munich ChronoType Questionnaire (MCTQ) will be used to identify the chronotype and social jet lag, in addition to specific questionnaires to assess the socio-economic-demographic situation and the fatigue and depression levels. Nonprobability sampling was used because it was decided to make the subjects' availability more flexible. PRELIMINARY RESULTS: The preliminary results were based on data collected from actigraphy (38 subjects), online survey application (47 subjects answered), and polysomnography (25 subjects). The application of the questionnaires in the sample produced a set of data with 47 participants quantified in 246 random variables. The sample, non-probabilistic and for convenience, is characterized by 34 women and 13 men, which correspond to about 72% and 28% respectively. All subjects have been working in shifts for at least 5 years. Regarding mood states, it was observed that nurses are more depressed than anxious, although both scores were high. The most fatigued, with higher levels of sleepiness (75% for both situations), with worse self-reported quality of sleep (91.3%), and low IS values, however, they were only attributed to nurses who are submitted to shift work from 5 to 7 years, regardless of the type of shift. From the actigraphy data, it was observed that the IS values tend to be lower in this last group as well, showing an unstable rhythm among the participants. Still in this segment, a lower IV was observed when the individual works on a day shift or alternated in another employment relationship besides SAMU. Finally, it was observed that these professionals express an unstable rhythm, poor sleep quality, characterized by high levels of depression and anxiety.

9
  • Francisco Edvaldo de Oliveira Terceiro
  • INTERDEPENDENCE AND THE COOPERATIVE BREEDING SYSTEM: INSIGHTS FROM CAPTIVE AND WILD COMMON MARMOSETS (Callithrix jacchus)

  • Líder : ARRILTON ARAUJO DE SOUZA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • Carolus Phillipus van Schaik
  • Judith Maria Burkart Natalucci
  • MARIA EMILIA YAMAMOTO
  • PATRICIA IZAR
  • Data: 23-nov-2021


  • Resumen Espectáculo
  • The human social repertoire is one of the most puzzling phenomena and historically under examination by several philosophical and scientific traditions. Both the extent of that repertoire and the evolutionary process that fostered such a complex system are of particular interest for behavioural anthropologists. From this school of thought emerges a notable hypothesis tackling the evolution of our social behaviour, the cooperative breeding hypothesis (CBH). Cooperative breeding systems are present in group living species in which offspring receive extensive care from individuals other than their parents. Moreover, because of the prevalence of parental and, especially, alloparental care, this system is also characterized by life history attributes as well as behavioural peculiarities. The CBH posits that, under naturalistic conditions, the psychological and motivational mechanisms required for a cooperative breeding system to function smoothly might also support an increase in performance in a variety of socio-cognitive contexts and tasks. My approach was to explore the behavioural variation associated to contrasting interdependence levels in a cooperatively breeding primate species, namely the common marmoset (Callithrix jacchus). Interdependence, a concept referring to the situation that a subject impacts a conspecifics’ overall fitness, is generally high in cooperative breeders, but variation also exists. Hence, comparing intra-specific behavioral variation in marmosets under different levels of interdependence allows for valuable insights into the underpinnings of their cooperative breeding system. These insights have implications for our understanding of the evolution of the human social repertoire and further tests of the CBH. The overarching goal of my PhD thesis was to investigate the CBH by exploring interdependence-driven intra-specific behavioural variation. In the first three subsequent empirical chapters, I assessed C. jacchus’ behavioural outputs by looking into three biologically relevant behaviours, namely social tolerance, food sharing and reaction to conspecific’s distress. Lastly, I reviewed the cooperative breeding system by addressing its prevalent definitions and pitfalls, the ecological benefits to parents, offspring, and helpers, the possible evolutionary pathways for this system to emerge and thrive, and finally, the behavioural consequences of the cooperative breeding system. In chapter 2, my goal was to assess if common marmosets’ social tolerance is higher in captivity where food is readily available or in the more demanding wild setting. The main finding was that, unlike independently breeding primates, adult common marmosets displayed higher social tolerance toward each other in the wild setting where food is scarce and mutual interdependence to successfully raise offspring therefore high. The results in this chapter thus emphasize the crucial relevance of interdependence in the evolution of highly tolerant cooperative breeders and therefore has implications for our understanding of the origins of humans’ social tolerance and hyper-cooperation. In chapter 3, the goal was to investigate how wild-living C. jacchus adjust their food-sharing behaviour towards infants as food availability varies. The primary finding was that all common marmosets, except female helpers, engage in an interdependence-driven strategy in which decreasing food availability increases food-sharing behaviour toward infants; this was also the case for older infants and for hard to obtain food items. Despite playing a relevant role overall in infant care, female helpers engage in an ecologically driven strategy and thus share food to infants more often when food is more abundant. This chapter helps us to illustrate how C. jacchus’ behavioural variation is remarkably reliant on interdependence levels. Additionally, it consolidates the interconnection between the cooperative breeding and interdependence hypothesis and their role in the evolution of the cooperative breeding system. Finally, in chapter 4, the ultimate objective was to evaluate how common marmosets react to conspecifics in distress and try to disentangle if emphatic rather than selfish motivations would govern these reactions. I found that all group members displayed contagion of emotional arousal, a previously unknown behaviour in common marmosets, thus indicating that common marmosets have a larger social repertoire than previously thought. Furthermore, I also found that male individuals were more likely to approach conspecifics in distress than relaxed ones, a finding consistent with the more conspicuous proactive prosociality from male common marmosets. Altogether, these results from chapter 4 highlight C. jacchus’ empathic competence in light of the combination model framework and helps us to better explain the emergence of empathetic capacities by moving the spotlight from large-brained species to highly interdependent ones. Overall, the main findings from this thesis reflect how interdependence is a driving force for social tolerance and food sharing in the cooperatively breeding common marmoset. Moreover, they also support the importance of social environments shaped through reproductive interdependence for the evolution of complex social skills in our model species, without the presence of large brains and its ensuing computational potency. Notably, the underlying finding from my thesis is the usefulness of interdependence variation as a tool to manipulate and thus expand our comprehension regarding the cooperative breeding system. Furthermore, interdependence appears to work as a linchpin for the cooperative breeding system, and therefore, its controlled manipulation might be used to assess a whole host of behavioural outputs from other species under this system and further explore the cooperative breeding intricacies.

2020
Disertaciones
1
  • HELOYSA ARAÚJO SILVA
  • Fish like us: individual differences and effects of alcohol in zebrafish

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • CARLA DENISE BONAN
  • RAMÓN HYPOLITO LIMA
  • Data: 05-mar-2020


  • Resumen Espectáculo
  • Alcohol is a licit drug. Exaggerated consumption of this substance is known as alcoholism and is among the most devastating problems of drug abuse. Acute drug consumption affects the neural system, culminating with alterations in neural circuitry homeostasis and the behavior of the individual. To evaluate these mechanisms, zebrafish (Danio rerio) has been considered a model, standing out due to its homology of about 70% of the human genome, high fecundity and maintenance. Several studies had shown a relationship between behavioral characteristics and alcohol consumption, a gap that has not yet been filled due to the high variability of its results, often derived from individual differences between the experimental subjects. Recently, it has been demonstrated that these individual differences result from genetic factors, environmental factor, metabolism, ontogenesis and personality, among others. In this sense, this study will evaluate, through behavioral tests and the effect of alcohol in the different behavioral profiles of zebrafish, in order to establish relationships between individual differences and propensity to alcoholism.

2
  • FELIPE AUGUSTO CINI DA SILVA
  • Acute application of d-LSD improves cognitive performance in object recognition and aversive conditioning tasks

  • Líder : SIDARTA TOLLENDAL GOMES RIBEIRO
  • MIEMBROS DE LA BANCA :
  • DRAULIO BARROS DE ARAUJO
  • FERNANDO MAZZILLI LOUZADA
  • SIDARTA TOLLENDAL GOMES RIBEIRO
  • Data: 16-mar-2020


  • Resumen Espectáculo
  • The aging processes lead to cognitive decay, evidenced by the deficit in working memory, attention and problem-solving. These changes are caused by a long list of physiological processes, including lower rates of plasticity, decreased arborization and less dendritic spines. Research shows that the application of classic psychedelics, agonists of serotonin 2A receptors, such as lysergic acid diethylamide (d-LSD), psilocybin, ayahuasca, 5-MeO-DMT can cause changes in brain function that persist long after the acute effects. Also, serotonergic agonists induce gene expression related to synaptic plasticity and promote functional and structural neural plasticity. Thus, this project aims to investigate whether different acute doses of the serotonin agonist d-LSD in animals of different ages, young (2-3 months), adults (8-10 months) and old (12-18 months) can modulate in the long term (7 or 14 days) the cognitive performance of Wistar rats in object recognition (ORT) tasks. We also evaluated whether the serotonin agonist can modulate aversive conditioning tasks (ACT) and the elevated plus-maze (EPM) in adult animals. We found that a single dose of d-LSD increases the preference for the new object in young and adult animals. d-LSD alone did not recover performance in old animals, but when it was combined with environmental enrichment there was a significant increase in novelty preference in old animals. Adult rats also showed higher rates of freezing in the ACT and greater time spent in the open arms of the LCE. Thus, our results show that d-LSD appears to positively modulate memory and learning in cognitive tasks, while at the same time decreases the anxiety levels of these animals. Our results also show that d-LSD has the potential to promote cognitive recovery in old animals.

3
  • MARIA ELISA LEITE FERREIRA
  • Behavioral differences in the response to alcohol in juveniles of zebrafish (Danio rerio).

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • CARLA DENISE BONAN
  • VANESSA DE PAULA SOARES RACHETTI
  • Data: 16-mar-2020


  • Resumen Espectáculo
  • Alcohol (ethanol or ethyl alcohol) is undoubtedly the most widely used legal drug of abuse in the world. The excessive use of this substance can cause alcoholism, one of the most devastating diseases among those related to drugs of abuse. The reinforcing effects of moderate alcohol use are the result of the interaction with neurotransmitter systems such as, for example, dopamine (DA), serotonin (5HT), gamma-aminobutyric acid (GABA), and glutamate, and neuromodulator systems such as adenosine. However, we know that some individuals are more sensitive to the effects of alcohol while others are more resistant, a response that may be related to genetic and environmental / social factors. Determining the relationship between the behavioral profile and alcohol use is difficult, since both the individual's behavioral and neurophysiological analysis must be taken into account. In order to better understand the above cited aspects of alcohol consumption, the zebrafish has become a promising model animal, because it offers the chance to investigate alcohol and individual differences effects, it presents classic vertebrate neurotransmitters, and shows high genetic similarity with humans. Another advantage is the well-known behavioral repertoire derived from zebrafish alcohol exposure, which also shows similarities to human behavior. In this sense, this work evaluated through behavioral tests whether individual differences established early in life can be predictive of the effects of alcohol consumption.

4
  • IARA BEATRIZ SILVA FERRÉ
  • Dynamics of cortical neural activity during pedaling: modulation by visual stimuli

  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • ALEXANDRE HIDEKI OKANO
  • EDGARD MORYA
  • JOHN FONTENELE ARAUJO
  • Data: 16-mar-2020


  • Resumen Espectáculo
  • Bicycling has been proposed by several studies as a therapeutic procedure for patients with Parkinson Disease (PD), particularly to motor rehabilitation. The act of pedaling in these patients is related to an improvement of motor impairments, to reduction of tremors as well as in improvements in bradykinesia and cognition. The neurobiological mechanisms underlying these effects are little understood. It is known that pedaling suppress the beta-band activity (13-35Hz) in the cortex and subthalamic nuclei. It has been suggested that this effect is a consequence of activation cortical circuitry by sensorial proprioceptive feedback from the lower limbs while pedaling, which is a simpler movement than walking, since the pedal connect the two legs. It is also well known that visual stimulation modulates the neural activity by allowing the emergence of spontaneously cortical patterns. Objective: The main objective of this work was to study the neural activity of healthy volunteers through an electroencephalogram record while they pedal with and without visual temporary deprivation. Methods: Forty-two healthy undergraduate students (19 female) aged 18-28 years old participated of the study. In the experiment, the volunteers alternated between rest and pedaling phases on an ergometric horizontal bicycle in two different conditions: without (open eyes) and with visual deprivation (by wearing a blindfold). The pedaling movements were performed in two cadences, 40 and 80 rotations per minute. We recorded an electroencephalogram of the participants during the experiment and calculated the maximum power and maximum power frequency for the alpha (8-12Hz), low beta (13-22Hz) and high beta (23-35Hz) bands. Results and discussions: The movement of pedaling resulted in a lower maximum power of high beta activity when compared to resting. We found no effect of visual deprivation on max. power for beta bands. Thus, visual deprivation does not contribute to a lower neuronal recruitment beyond that resulting from pedaling. We also found no difference between the two cadences. These findings are similar to previous studies and support the relevance of pedaling as an therapeutic sport to people with PD. Regarding visual deprivation, we think that other studies should be done to better investigate the relationship between visual system and PD. Conclusions: High beta activity is suppressed by pedaling movement. This is one more research to clarify the effects of bicycling on the brain and the mechanisms underlying the therapeutically effect of pedaling in PD.

5
  • ADRIELLY MARCELA DE CASTRO DO NASCIMENTO
  • I'ts a date: evaluation of individual differences in a speed-dating

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • FELIPE NALON CASTRO
  • JAROSLAVA VARELLA VALENTOVA
  • Data: 17-mar-2020


  • Resumen Espectáculo
  • Reproduction is necessary to pass the genes to the next generation. All the living beings have evolved behavioral and physiological mechanisms to maximise the benefits and minimise the costs of reproduction, one of them is mate choice. In humans ancestors this choice could represent also the choice for cooperation partners, this may favor some preferences to be selected over others. Over the years many studies analysed the human preferences. But most of them do not evaluate the preferences of non-heterosexual individuals and use romantic partner idealisation. The aim of our study is investigate the differences in preferences for individual characteristics, as personality and attractiveness, between sex and sexual orientation. For this, we applied questionnaires and realized an experiment of speed-dating. In the first empirical article, we aimed to analyze the use of different methodologies in the assessment of partner choice and show the relation between them and the profile of speed-dating participants. Our results show that speed-daterers consider themselves more attractive and with more resourceful than individuals who do not participate in speed-dating. The second article evaluated the individual characteristics such as attractiveness and self-assessment as a romantic partner the relationship between them and their influence on the idealization and choice of a romantic partner. Our results showed that self-perception influences individuals' self-esteem; in addition, this self-perception influences idealization and choice, but with differences between genders. In our third article we assessed the importance of attractiveness and personality in the choices for different relationship contexts Our results show that attractiveness appears to play a more important role for the long-term than personality traits, but only for women. This study shows that there are several relationships between different individual characteristics in the process of choosing a partner, and that these relationships seem to differ according to the sex and sexual orientation of individuals, in addition to being context dependent. In this way, more studies that aim to evaluate the choice closest to the real are necessary, being able to use the speed-dating method.

6
  • EMANNUELLY SEBA DE MEDEIROS
  • Subjective Well Being from the perspective of evolutionary psychology and positive psychology

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • ANUSKA IRENE DE ALENCAR
  • VALESCHKA MARTINS GUERRA
  • Data: 17-mar-2020


  • Resumen Espectáculo
  • Throughout the time, science has dedicated itself to understanding the mechanisms of various mental pathologies, which has led to essential discoveries in the treatment and understanding of numerous health complications. The evolutionary perspective has made an important contribution in the identification of such mechanisms, both with regard to their biological bases in normal functioning and changes associated with pathologies. However, there are relatively few studies based on the understanding from such a perspective of positive aspects of mental functioning such as human strengths and virtues and how this is reflected in people's overall well-being. It is currently known that subjective well-being involves a number of factors that include the inheritability of the propensity for well-being, as well as cultural, social, family and relationship contexts that can modulate their understanding. In this sense, the present study aims to present an evolutionary view of the perception of subjective well-being, including an articulation with practices belonging to Positive Psychology, such as the practice of gratitude, meditation of induction of positive affects and development of character forces, since such tools may be useful for arousing positive aspects, especially in self-critical individuals.

7
  • CATARINA ZULMIRA SOUZA DE LIRA
  • CORRELATES OF BIOPSYCHOSOCIAL VARIABLES IN THE PAIN SCENARIO CHRONICLE: FATIGUE AND CHRONOBIOLOGICAL PARAMETERS IN WOMEN WITH SYSTEMIC LUPUS ERYTHEMATOSUS.

  • Líder : MARIO ANDRE LEOCADIO MIGUEL
  • MIEMBROS DE LA BANCA :
  • JOHN FONTENELE ARAUJO
  • MARIA JOSE PEREIRA VILAR
  • MARIO ANDRE LEOCADIO MIGUEL
  • Data: 19-mar-2020


  • Resumen Espectáculo
  • Systemic Lupus Erythematosus (SLE) is known to have an impact on the health of individuals and is supported by a network of multiple factors that culminates in its various chronic consequences, such as symptoms of pain, fatigue, changes in sleep patterns and changes in humor. OBJECTIVE: to reflect on the interrelationships between sleep, fatigue and pain parameters in patients with SLE, as well as to search for new markers that can influence their behaviors, such as mood, rest-activity rhythm and exposure to light . METHODOLOGY: The research design is characterized as a cross-sectional observational study with the residences of patients (for physically limited patients) and the Laboratory of Neurobiology and Biological Rhythmicity (LNRB) of UFRN as their collection point, where 8 validated questionnaires were applied, divided into 2 stages interspersed by the use of the Actimeter in 2 groups of women, with and without the diagnosis of SLE. Descriptive statistical analyzes of the obtained variables were carried out, including the determination of the characteristic of the distribution of each variable and later the inferential statistical analysis in order to seek the differences between the groups and the relationships between the variables mentioned above. RESULTS: 46 variables were analyzed in order to clarify the scenario experienced by patients with Systemic Lupus Erythematosus. Differences between groups were found for variables of pain, fatigue, quality of sleep, social jetlag, depression, variables of exposure to light and relative amplitude of the activity-rest rhythm. In the lupus group, an association was found between fatigue and pain, as well as between pain and sleep, but the same did not happen for fatigue and sound, with fatigue being justified by perceived stress. Only subjective sleep variables were associated with the activity level of the disease and over-spending was predictive of sleep efficiency. Variables in the rhythm of activity and rest were associated with sleep variables, but only L5 was a predictive variable for sleep duration. Anxiety was able to predict disease activity and this in turn was responsible for the behavior of subjective pain variables. CONCLUSION: The findings demonstrate that it is important to consider chronobiological variables, from exposure to light, activity-rest rhythm and sleep-wake cycle, in the treatment of patients with Systemic Lupus Erythematosus and that mood control contributes to the modulation of disease activity .

8
  • ALAN MICHEL BEZERRA FURTUNATO
  • Electrophysiological characterization of the delta and theta oscillations of the dorsal hippocampus of rats during running on a treadmill

  • Líder : BRUNO LOBAO SOARES
  • MIEMBROS DE LA BANCA :
  • BRUNO LOBAO SOARES
  • CLEITON LOPES AGUIAR
  • HASSAN MOHAMED ELSANGEDY
  • Data: 09-jun-2020


  • Resumen Espectáculo
  • The hippocampal theta rhythm (6-10 Hz) was extensively studied along the literature and has involved with cognitive functions, sensory-motor integration, paradoxical sleep and locomotion. And was well characterized along the septo-temporal hippocampal axis. However, the delta rhythm (0.5-4 Hz), commonly investigated on the slow-wave sleep, inactivity, anesthesia and epilepsy seems to be widespread over multiple cortical and subcortical areas as theta oscillations. What is coherent with the literature, once that slow frequency oscillations allow the exchange of information of neuronal assemblies between distant brain areas. In the present work, we proposed an electrophysiological characterization of theta and delta oscillations through two distinct locomotion protocols on a treadmill, on the hippocampal area of CA1 dorsal of rodents. In the first manuscript, we take data of the electrophysiological register of 3 long-evans male rats submitted to 11 sessions (n=11) of 35 runnings of 15 s at 30 cm/s on a maze task. Where we observed an increase and a gradual decrease of the delta and theta power, respectively across the runnings. Beyond that, an increase of the interhemispheric phase coherence of the delta band. Next, on the second manuscript, we take electrophysiological registers of the local field potential in 6 male rats of wistar lineage on 22 sessions (n=22) of 48 bouts of 20 s on 3 accelerated speeds (1, 1,5 and 2cm/s) and 3 constant speeds (20, 30, 40 cm/s) escalated on a sequence of 8 blocks of 6 runs. Trough these protocols we verified that delta oscillations showed an increase of power meanwhile theta oscillations showed a power decrease along of the runnings. Yet, the hippocampal delta oscillation of rodents showed a significative increase in power and frequency on runnings at highest speed. Together, our results suggest that the hippocampal delta oscillation has function on the physiological condition signaling of the experimental subject, which could serve as a signaling parameter of the fatigue levels on rodents along of successive runnings.

9
  • LÍVIA RODRIGUES NEVES
  • Standardization of spatial pattern separation task in rats - behavioral and electrophysiological investigation
  • Líder : BRUNO LOBAO SOARES
  • MIEMBROS DE LA BANCA :
  • BRUNO LOBAO SOARES
  • DIEGO ANDRES LAPLAGNE
  • FLAVIO FREITAS BARBOSA
  • Data: 23-jun-2020


  • Resumen Espectáculo
  • The formation of new memories is one of the humans and others animals fundamental cognitive capacities. Pattern separation is one of the involved processes in episodic memories encoding, which can reduce interference between similar sensory information and as a effect may facilitate the formation of a new memory that represents the environment in a more refined way. Previous studies revealed that neural oscillations, like theta and gamma, are associated with the encoding of mnemonic informations in the hippocampus, one of the main encephalic regions related with episodic memory formation. However, the relationship of these oscillations to the pattern separation processing in the hippocampus is not well understood in the literature. Therefore, in this project we focus on the process of spatial pattern separation using the object recognition paradigm to look into its repercussions on the neural rhythms of the hippocampus through behavioral and electrophysiological investigations. We evaluated the involvement of theta and gamma neural oscillations in the spatial novelty discrimination of displaced objects in two conditions called high and low interference. To this end, we standardized a new behavioral protocol and simultaneously recorded CA1, CA3 and dentate gyrus local field potential (LFP) of adult male Wistar rats. As a result, we saw that (1) animals showed a preference for exploring the displaced object in both test conditions, and that (2) discrimination index was higher for low than high interference conditions, that is to say, when the object is more displaced from its original position. As a result of the electrophysiological investigation, we observed that (1) there was no significant difference in the theta band (6-10 Hz), and that (2) there was an increase in gamma power in CA1 and CA3 hippocampal areas depending on the object to be explored. In the comparison between displaced objects in BI and AI, CA3 presented greater low gamma power (35-55 Hz) during exploration of the object most displaced from its original position (i.e., BI condition). When comparing displaced and stationary objects in each one of the tests, we found greater low and high gamma power in CA1 (65-90 Hz) during the exploration of the stationary object. Our results suggest that gamma power in CA1 is related to memory recall of objects previously found in their original positions, while the low gamma power in CA3 is related to encoding of new object’s spatial locations. These findings provide an overview of the neural processing dynamics underlying task resolution, and indicate that different areas of hippocampal circuitry are differentially involved in spatial pattern separation.
10
  • ANNA CAROLINA NOGUEIRA BORZANI
  • Individual differences in show jumping horses (Equus cabalus) – a methodological comparison study
  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • ALINE CRISTINA SANTANNA
  • FIVIA DE ARAUJO LOPES
  • RENATA GONCALVES FERREIRA
  • Data: 08-sep-2020


  • Resumen Espectáculo
  • Stable differences in behavioral patterns, also called personality, have been studied in farm animals, particularly to improve their welfare and production. In horses, studies show that personality is linked to performance, risk of accidents, and animals’ health. The most common traits in horse personality are: reactivity, gregariousness, reactivity to humans, sensory sensitivity and locomotor activity. However, methodologies for studying personality in horses vary, with few studies testing for consistency in personality structure. Our objective was to test whether different methods (questionnaire, test and behavioral observation) present congruent results when assessing a horse's personality. This study included 40 animals housed in two riding schools, one in Natal / RN and another in João Pessoa / PB. We used a personality questionnaire with 24 adjectives, which was answered by at least two people. In addition, the animals participated in six personality tests, which were repeated after one month, being: reactivity (three tests), neophobia, gregariousness and reactivity with humans. Finally, we performed 60 min of behavioral observation of the animals in the stall. To verify the temporal consistency and among the respondents, we used analysis of interclass correlation tests. With the relevant variables, we performed principal component analyzes to define the dimensions found by each method. As a way to check the consistency between methods, we performed the Person test with the values of Z-scores of the individuals in each factor found. Of the adjectives in the questionnaire, only nine were considered valid and grouped into two characteristics: sociability and openness. Seventeen out of 34 variables from tests showed e temporal consistency test and were grouped into six traits: fear, locomotor activity, sociability towards human beings, neophobia, aggressiveness towards human beings and food. The behavioral observation variables comprised six stereotyped behavior groups: locomotor, related to food, social eating, threatening, restlessness and scratching. Six correlations were found between all traits that suggests the existence of only one personality axis: proactive-reactive or bold-shy. Locomotor behavior in the tests, openness to new experiences in the questionnaire and threatening behavior in the stall was considered a proactive behavioral syndrome. Reactivity in the tests had a negative correlation with neophobia and a positive correlation with food stereotypes and scratching, indicating more reactive animals. Altogether, we found more correlations between tests and behavior than between these and the questionnaire, suggesting that different methods may not be measuring the same personality traits. The use of diverse methods in conjunct reveal that individual differences in horse can be resumed in one single proactive-reactive axis.

11
  • MIRELLA SALGUES DE CARVALHO
  • Behavioral effects of tamsulosin - selective α1A adrenoceptor antagonist - in mice

  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ELAINE CRISTINA GAVIOLI
  • EDILSON DANTAS DA SILVA JUNIOR
  • ISABELLA MARIA DE OLIVEIRA PONTES FERNANDES
  • Data: 06-oct-2020


  • Resumen Espectáculo
  • Tamsulosin is the main form of treatment of urinary symptoms in patients with benign prostatic hyperplasia. This selective α1A adrenoceptor antagonist acts on both smooth muscle cells of the prostate and in other regions of the central nervous system. Studies suggest that the use of this drug can increase the likelihood of developing depression, dementia and anxiety in treated patients, possibly because tamsulosin can cross the blood-brain barrier. A recent study used DAT-IRES-Cre knock-in animals to evaluate the role of the limbic system in modulating resilience to stress and the results suggested that adrenoceptors play an important role in this process. In addition, it has been shown that transgenic mice expressing constitutively active mutant α1A adrenoceptors presented antidepressant-like phenotype and improvements on general cognition. In the present study, we sought to evaluate the effects of acute treatment with tamsulosin in male mice behavior through forced swim test, elevated plus maze and open field. The results obtained show that tamsulosin was capable of promoting hypolocomotion in the animals treated with the dose of 0,1 mg/kg; it was capable of promoting and increase in immobility time in mice treated with the doses of 0,01 mg/kg and 0,1 mg/kg; and it was not capable of altering the percentage of number of entries, the percentage of time spent at the open arms nor the number of entries on the closed arms. In conclusion, this study points a possible relation between tamsulosin and an increase in vulnerability to stress, which could explain the apparent pro-depressive effect as a result of the use of this medication by patients with BPH.

12
  • DIEGO DE AQUINO CÂMARA
  • Phase-dependent effect of reserpine in promoting behavioral deficit and neurochemical alteration in the nigrostriatal pathway of rats
  • Líder : ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • MIEMBROS DE LA BANCA :
  • JEFERSON DE SOUZA CAVALCANTE
  • JOSÉ RODOLFO LOPES DE PAIVA CAVALCANTI
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 06-oct-2020


  • Resumen Espectáculo
  • Reserpine induces a failure in the storage capacity of monoamines in synaptic vesicles, generating a depletion of these substances in the terminal nerve and an increase in oxidative stress. A large body of evidence shows that this drug causes the appearance of motor and non-motor symptoms similar to those seen in Parkinson's disease, with its common application protocol resulting from a light phase, using nocturnal animals as the main experimental model. Some studies, however, realization that in the light phase there is a lower concentration of antioxidants in the animal body, nocturnal animals due to daily fluctuations in the production of enzymes such as catalase and superoxide dismutase, in addition to the neurohormone melatonin, which show peaks during the dark. These oscillations, therefore, can represent a phase-dependent vulnerability to disorders resulting from damage to a DNA structure, lipid peroxidation and protein oxidation. Many parameters of biological rhythmicity are not taken into account when standardizing experimental models, which can distance the animal results from the pathophysiology of some disorders. In view of the interactions of circadian machinery and EO, the objective of this work is to observe whether the pharmacological model of reserpine in rats (Santos et al., 2013), when provided during a dark phase, has the same effect of inducing symptoms DP engines compared to their standard application protocol in the clear phase, as well as neurochemical changes in the nigroestrital pathway. 41 animals were used with an approximate age of 3 months. The animals were prepared for the administration of reserpine in two distinct phases, activity and rest; the effect of the drug on behavior was assessed using the catalepsy test. The animals also have a group assessment of the rest-rest rhythm throughout the experimental procedure. Subsequently, neurochemical parameters related to the quantification of dopaminergic neurons were adopted. The administration of reserpine does not change changes in the activity / rest period of the groups. In catalepsy test we observed that animals treated with the drug had the expected motor loss at the end of the protocol, however the group that has received the treatment with reserpine during the night had the beginning of this motor loss later, in relation to the group that has received the treatment during the day. In the neurochemical evaluation, it was not seen a neuronal loss consolidating in the substancia nigra pars compacta (SNpc) and substancia nigra lateral (SNL), only a ventral tegmental área (VTA) revealed a meaning neuronal loss in the group that includes a reserpine during the night in relation to its control group.

13
  • MARLON BARBOSA DANTAS DE CARVALHO
  • Participation of the hypothalamus-hypophysis-adrenal axis in modulating the depressive type behavior induced by the activation of nociceptin/orphanin FQ receptor

  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ELAINE CRISTINA GAVIOLI
  • FABIANO PERES MENEZES
  • JULIA JENSEN DIDONET
  • Data: 22-oct-2020


  • Resumen Espectáculo
  • Several studies have linked the N/OFQ-NOP receptor system with depressed mood disorder. Despite the notorious antidepressant effects of NOP antagonists in different behavioral tests and animal models of depression, little is known about the behavioral actions of NOP agonists under stress conditions. The present study aimed to investigate the participation of the hypothalamic-pituitary-adrenal (HPA) axis in the NOP agonist-induced depressive-like behaviors in mice treated prior to the first exposure to the forced swim test. The effects of the treatment with the tricyclic antidepressant nortriptyline, a NOP agonist (Ro 65-6570) and a NOP antagonist (SB-612111) before exposure to forced swimming stress was investigated. In addition, in order to evaluate the participation of the HPA axis in the effects of the NOP agonist (Ro 65-6570) in the forced swim stress, mice were pretreated with CRF1 receptor antagonist (NBI 30755), glucocorticoid receptor antagonist (mifepristone) and glucocorticoids synthesis inhibitor (aminoglutethimide). Firstly, the administration of the nortriptyline prior to exposure to the forced swim did not affect mouse behavior when compared to the control group. However, an increase in the immobility time was observed in mice treated with the NOP agonist, Ro 65-6570, while a decrease in the immobility time was detected in those animals treated with the NOP antagonist, SB-612111, being both drugs administered before stress, when compared to the control group. Finally, it was observed that the effects of Ro 65-6570 in the immobility time were blocked when mice were pretreated with mifepristone, NBI 30755 or aminoglutethimide. However, there were no effects of the HPA axis blocking agents per se on the behavior of mice in the forced swim stress. In conclusion, the activation of NOP receptor promotes depressive-like effects, while the blockade produces opposite effects. In addition, the depressive-like effects of NOP agonists appear to be mediated by the HPA axis.

Tesis
1
  • LUIZ EDUARDO MATEUS BRANDÃO
  • 6-OHDA effects on rest-activity rhythms and the circadian expression of histamine in the central nervous system of rats

  • Líder : JEFERSON DE SOUZA CAVALCANTE
  • MIEMBROS DE LA BANCA :
  • FELIPE PORTO FIUZA
  • JEFERSON DE SOUZA CAVALCANTE
  • MARIO ANDRE LEOCADIO MIGUEL
  • MAXWELL BARBOSA DE SANTANA
  • YWLLIANE DA SILVA RODRIGUES MEURER
  • Data: 29-may-2020


  • Resumen Espectáculo
  • Parkinson Disease (PD) is a neurodegenerative disease mainly characterized by a progressively dopaminergic depletion on central nervous system (CNS). Furthermore, PD patients exhibit non-motors symptoms like sexual dysfunction, cognitive impairment, olfactory damage, depression, anxiety, sleep disturbs, circadian disruptions and others signs. These non-motors symptoms are result of neurochemical changes in others neurotransmission circuitries like noradrenergic, cholinergic, serotoninergic and/or histaminergic systems. Human post mortem studies showed alterations in histaminergic receptors and neural projections distribution throughout the CNS of PD patients. Moreover, studies based on neurotoxin infusion reinforced this relationship between the histaminergic system and the physiopathology process of PD. In mammals, the histaminergic system controls alertness and wakefulness status, acting as an essential component of sleep-wake regulatory system. Here, we used an intracerebroventricular infusion of 6-hydroxydopamine as a pharmacological tool to induce rest-activity rhythm fragmentation and investigated what types of rhythmic parameters were affected and how the wake-promoter histaminergic system contributes with this phenomenon. Our protocol induced a progressive rest-activity rhythm impairment, without changing histidine decarboxylase or bmal1 protein expression in tuberomammilary or suprachiasmatic nucleus. Parametric and non-parametric rhythm analyses were conducted to describe the impairment of rest-activity rhythm as a progressive circadian dysfunction with increased fragmentation/variability on animal activity throughout the day, as well as a reduced stability of this activity pattern between consecutive days within both entrained and constant conditions (i.e. light-dark and constant darkness schedules, respectively). We conclude that dopamine exerts an important role on rest-activity rhythm regulation, in both synchronized and constant photoperiods, without affecting the histaminergic tonus.

2
  • ANA KELLY DE ALMEIDA
  • The use of the Somatic Experiencing®-SE ™ method and its effectiveness in a sample of men with clinical diagnosis of Post-Traumatic Stress Disorder (PTSD)

  • Líder : MARIA BERNARDETE CORDEIRO DE SOUSA
  • MIEMBROS DE LA BANCA :
  • LIANA RODRIGUES NETTO
  • CÍNTIA SATIKO FUZIKAWA
  • EMERSON ARCOVERDE NUNES
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • MELYSSA KELLYANE CAVALCANTI GALDINO
  • PAULA ADRIANA BORBA
  • Data: 02-jun-2020


  • Resumen Espectáculo
  • Posttraumatic Stress Disorder (PTSD) is essentially characterized by the development of clinical symptoms of a psychological, physiological and behavioral nature after exposure to one or more traumatic events that may vary between different individuals, presenting different combinations of symptomatic patterns included in the diagnostic criteria of the disease (DSM-IV). In the contemporary world, violence in urban centers is increasing, with the occurrence of assaults or robberies followed by death that lead to the onset of PTSD. Evidence from studies on the neurobiology of PTSD has shown neural systems particularly involved in its pathophysiology and different types of treatment approaches. For example, there are several approaches and therapeutic methods of a psychological nature, including the SE ™ method - Somatic Experiencing® (Somatic Experience), focused on improving the symptoms of chronic stress and post-traumatic stress. In this context, the objectives of this study involve 3 aspects related to PTSD: (1) to review the state of the art in the use of complementary psychological treatments in PTSD; (2) to investigate possible changes in psychometric scales and biological markers associated with the treatment of PTSD using the SE™ technique in adult men, victims of assault in the city of Natal, with and without pharmacological treatment , and (3) to validate, from a sample of the adult population in general (n = 452; xx men and xx women), a structured questionnaire for screening and verifying PTSD symptoms, based on the DSM-5. In the first study, a systematic review was carried out, where few studies were found, using techniques such as Yoga, Mindfulness, Brainspotting and the SETM method particularly for the latter. In the second study, a sample consisting of 23 participants was used, divided into two groups, six of whom were using (GM) and 17 were not using medication (GS) for PTSD, to investigate the effectiveness of the treatment using the SETM method. The results showed a significant decrease in the PTSD Impact scale and negative Affection scale, in the absence of difference between cortisol levels before and after therapy. There was also a significant increase in the associated Positive Affection scores and an increase in the Perception of Wellbeing scale, the latter being followed up 3 months after therapy. The results in relation to the Impact, Affection and Perception of well-being scales were similar to those of the GM, for individuals in the GS group as a whole (n = 17), before and after therapy. In GS, in addition, the mean values for cortisol and CRP also remained unchanged when the conditions before and after SETM were compared. When the GS group was separated considering the degrees of mild, moderate and severe PTSD, a difference was found in the psychometric scales between the mild and moderate degrees in relation to the severe, in terms of greater decrease in symptoms after SETM. However, there were no significant differences when considering the classification of PTSD in acute and chronic. It can be suggested that the effectiveness of SETM was significant and that both medicated and unmedicated patients benefited equally from this therapy. Thus, it can be suggested to use SETM as a complementary treatment that can be better used by professionals who work with PTSD. Study 3 aimed to validate an instrument based on DSM-5 for the diagnosis of Posttraumatic Stress Disorder (PTSD) in assault victims. The proposed scale was constructed with 41 items and answered by 408 participants (254 women and 154 men), resulting in four empirical factors, grouping items of different symptomatic criteria of PTSD (Hyperstimulation, Difficulties of cognition and hHumor, Intrusion and Avoidance). The exploratory factor analysis, covering the analysis of the main components and factor loads, indicated a one-dimensional construct on the scale. The four factors (Hyperstimulation, Cognition and mood difficulties, Intrusion and Evitation) presented values of internal consistency calculated by the Cronbach's Alpha test equal to 0.94, 0.83, 0.94 and 0.70, respectively. The means obtained from the four factors of the groups of subjects diagnosed (n = 152) and not diagnosed with PTSD (n = 249) was significantly different (p = 0.000). In this sense, it was possible to demonstrate a strongly significant correlation between the factors and the score of the Event Impact Scale.

3
  • KARLYNE MACIEL GADÊLHA DOS ANJOS
  • Relation between sleep habits, use of electronic media and attention: a comparison between adolescents from the urban and suburban areas of the Metropolitan Region of Natal /RN

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • KATIE MORAES DE ALMONDES
  • IVANISE CORTEZ DE SOUSA GUIMARAES
  • FELIPE BEIJAMINI
  • KATHIANE DOS SANTOS SANTANA
  • Data: 29-jun-2020


  • Resumen Espectáculo
  • The objective of this study was to evaluate the relation between use of electronic media and degree of urbanization of living areas with the sleep-wake cycle and attention components in adolescents. 214 adolescents between 12 and 18 years-old, of both sexes, participated in the study, being 111 from the suburban area and 103 from the urban area, enrolled in the 8th and 9th years of Elementary School II in morning shift of the Rio Grande do Norte/Brazil public school system. The sleep-wake cycle was assessed by the questionnaires “Health and Sleep”, “Pittsburgh Sleep Quality Index”, “Morningness-Eveningness questionnaire” and “Pediatric Daytime Sleepiness Scale”; in addition to Sleep Diaries and actigraphy for 10 days. While attention, was assessed by the Continuous Performance Task. Most adolescents that have electronic devices in the bedroom, being cell phones the majority, have the habit of sending messages before going to sleep, listening to music and using it when waking up at night. Most people who share a bedroom with these adolescentes also report the use of cell phones in the bedroom. In the urban area, adolescents report: having greater proportion of TV in the bedroom and the habit of watching it before bed, having internet at home and on their cell phones and having greater proportion of internet access at home, but less internet access on their cell phones, than the suburban area. In addition, in the uran area, they have greater irregularity in get up time and more reports, during weekdays, of waking up only when someone calls them, in relation to those in the suburban area, who mostly wake up with alarm clock aid. There was also a greater tendency to eveningness and higher levels of daytime sleepiness in the urban area. Regardless of the area, adolescents presented poor sleep quality and claimed the use of an electronic device before going to sleep, at least one day per week, with greater frequency of use on weekdays. Regarding the components of attention, there was a higher percentage of correct responses in all components, greater general stability during the task, lower percentage of omissions in tonic alertness and selective attention and a tendency to have lower percentage of omissions in phasic alertness, in the urban area. As for the relation between use of eletronic media and degree of urbanization with sleep variables, the general multivariate linear model did not show associations between use of media and sleep variables. On the other hand, the urban area was associated with lower sleep efficiency on weekdays (β = - 0.64; p <0.01) and weekend, (β = - 0.70; p <0.01), lower sleep latency on weekend (β = - 0.31; p <0.01), greater number of nighttime awakenings on weekdays (β = - 0.69; p = 0.00) and weekend (β = - 0.64; p <0.01), greater irregularity in bedtime (β = 0.38; p <0.01) and get up time (β = 0.66; p <0.01) and had higher percentage of correct responses in selective attention (β = 0.26; p <0.01). In addition, the model pointed out that girls have higher levels of daytime sleepiness (β = - 0.18; p = 0.04), lower sleep efficiency on weekdays (β = 0.17; p = 0.02), and fewer nighttime awakenings on weekend (β = 0.22; p <0.01) when compared to the boys. Thus, in both áreas, adolescents use eletronic media and have bad sleep habits. The urban area was associated with greater irregular sleep hours, worst sleep quality, greater daytime sleepiness, tendency to eveningness and better attentional performance.

4
  • JESSICA JANINE DE OLIVEIRA
  • Together by chance? Individual differences and romantic relationships

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • FIVIA DE ARAUJO LOPES
  • JAROSLAVA VARELLA VALENTOVA
  • NATÁLIA BEZERRA DUTRA
  • VICTOR KENJI MEDEIROS SHIRAMIZU
  • Data: 31-jul-2020


  • Resumen Espectáculo
  • In the last decades, studies with sexual selection in the human species have turned their attention to individual aspects, such as selfesteem, sociossexuality, personality, and attachment. Selfesteem is a social thermometre that indicates to an individual when he has to change his or her behavior. Sociossexuality can be defined as a behavioral tendency of one person engage in casual sex. Personality is a set of psychological traits, that are defined by the interaction between genetic predisposition and environment. The romantic attachment can be described as a set of behavioral tendencies that assists the individual to maintain emotional bonds. The aim of the present study was to investigate the relationship between selfesteem, sociossexuality, romantic attachment, personality, self perceived mate value, idealization of a romantic partner and relationship satisfaction in heterossexuals and nonheterossexuals individuals. 385 volunteers participated in the study, 219 were single and 166 were in a long term relationship. The participation consisted in answer a package of questionnaires. Our results show that heterossexual and non-heterossexual men and women differ in their idealization of a romantic partner, and that selfesteem influence the idealization of a romantic partner. On the other hand, selfesteem does not differ between single and committed participants. The sociossexual orientation, the personality traits and the attachment dimensions are different between different sex and sexual orientations. The romantic attachment and the personality traits were capable of predicting the self perceived mate value and the partners evaluation of the individual’s mate value. The romantic attachment, between the studied variables, was the most capable of predicting relationship satisfaction. We suggest that the evolution of selfesteem, personality and sociossexuality could have influenced the mate choice context and that romantic attachment influences the duration of one relationship.

5
  • FERNANDA CARVALHO CAGNI
  •  

    Effect of NOP receptor antagonist SB-612111 and imipramine in social defeat stress in Swiss mice
  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ELAINE CRISTINA GAVIOLI
  • MARCELO DUZZIONI
  • RAMÓN HYPOLITO LIMA
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • VANESSA DE PAULA SOARES RACHETTI
  • Data: 18-ago-2020


  • Resumen Espectáculo
  • Depression is one of the most prevalent mental disorders in the world. Despite the availability of pharmacological treatment, some patients are not responsive, others experience severe side effects, and the antidepressants take time to produce therapeutic effects. Thus, new antidepressants are needed. Nociceptin/orfanin FQ (N/OFQ) is an endogenous peptide that binds to an inhibitory receptor coupled to G protein, called NOP receptor. NOP receptor antagonists display antidepressant activity and are able to increase resistance to acute stress. However, there are few studies investigating the preventive effects of NOP antagonists in the development of behavioral changes induced by chronic stress, when chronically administered. The aim of this study was to investigate whether treatment with NOP receptor antagonist SB-612111 prevents the development of social defeat stress-induced behavioral changes. To this aim, male Swiss mice were subjected to 10 days of social defeat stress. It was observed that after 5 days of stress, animals showed slight behavioral changes that became significant after 10 days of social defeat, and that remained significant 7 days after stress ceased. The defeated animals displayed a longer immobility time in the tail suspension test (TST), spent lesser time in the center of the open field test (OF) and they significantly lose weight. However, no behavioral changes were detected in the social interaction test (SI). Repeated treatment with imipramine, a classic antidepressant, was carried out to validate the experimental conditions. Imipramine prevented the onset of depressive behavior in TST, but it did not protect against weight loss caused by social defeat. In addition, imipramine induced anxiogenic-like effects in the control group, while no effects were observed in the defeated mice in the OF. The repeated treatment with SB-612111, started concomitantly with social defeat stress, reduced immobility time in defeated animals 24 h and 7 days after the end of the stress, having no effects on the control group. In addition, due to the reduced sample size, other behavioral changes were not detected, thus impacting the investigation of the protective effects of this compound. In conclusion, SB- 612111, administered concomitantly with stress, showed lasting antidepressantlike activity in defeated animals, since the effects were observed 7 days after the end of the treatment. Neurochemical studies are necessary to support the potential increase in resistance to stress induced by blocking the NOP receptor under chronic stress conditions.

6
  • CLARISSA DE ALMEIDA MOURA
  • Prenatal stress: long-term effects on behavior and tryptophan metabolites balance

  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ELAINE CRISTINA GAVIOLI
  • HINDIAEL AERAF BELCHIOR
  • RENATA FIGUEIREDO ANOMAL
  • JANAINA MENEZES ZANOVELI
  • MARIA CAROLINA GONZALEZ
  • Data: 24-sep-2020


  • Resumen Espectáculo
  • Prenatal stress (PNS) directly interferes with fetal programming, a principle by which the mother's endocrine and metabolic environment can generate long-term consequences in adult offspring. Among the potential neurochemical pathways affected by PNS, the tryptophan metabolism by the kynurenine pathway is still poorly investigated. This study sought to investigate the behavioral and neurochemical consequences of PNS, with an emphasis on monoamines and metabolites of the kynurenine pathway, in the adult offspring of mice exposed to PNS. Pregnant females of Swiss mice were subjected to the restraint stress associated with intense light three times a day during the last week of gestation (days 14-21). The adult offspring of males and females submitted to PNS underwent behavioral tests, including: open field, object recognition task, elevated plus maze, social interaction and tail suspension test. For the neurochemical stage, the adult offspring were euthanized and their brains dissected in order to quantify the levels of tryptophan, quinolinic acid (QA), kynurenine, 5-hydroxyindole acetic acid (5-HIAA), serotonin (5-HT), dopamine and noradrenaline in the hippocampus and brainstem, using the mass spectrometry technique. The prefrontal cortex (PFC) of the offspring was also dissected in order to evaluate the gene expression of the following enzymes: indoleamine 2,3-dioxigenase (IDO), kynurenine monoxygenase (KMO) and kynurenine -aminotransferase 3 (KYAT3), through the real-time PCR technique. The results revealed that the adult offspring submitted to the PNS presented: (1) impairment in the object recognition task in the male and female offspring, with the latter being associated with the estrous cycle; (2) hyperactivity of the male offspring, accessed by the greater total distance travelled in the open field, as well as longer time spent in the closed arms in the elevated plus maze test, suggesting an anxious phenotype, with no changes in monoamine levels, but with changes in metabolites of the quinurenine pathway, defined by higher levels of QA in the hippocampus and brainstem and higher levels of kynurenine and tryptophan exclusively in the hippocampus, (3) increased immobility in the tail suspension test by the female offspring, suggesting a depressive profile, influenced by the phases of the estrous cycle, and associated with lower levels of 5-HT in the hippocampus and greater activity of 5-HT in the hippocampus and brain stem, (4) alteration in the gene expression of enzymes related to the kynurenine pathway, so that PNS females had higher expression of KYAT3 in the hippocampus and IDO in the PFC, while the male offspring showed reduced levels of KMO in the PFC. In conclusion, this study revealed a sex dependent behavioral and neurochemical profile as a consequence of late PNS in the mice offspring, evaluating the balance of tryptophan metabolites as a key point.

7
  • JORGE ALEXÁNDER RÍOS FLÓREZ
  • Neuroanatomical substrate of the cognitive and visceromotor circuits of the pre-limbic and infralimbic cortex of the medial prefrontal cortex; description of their projections and interactions with subcortical complexes in the primate Callithrix Jacchus

  • Líder : EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • MIEMBROS DE LA BANCA :
  • EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • FRANCISCO GILBERTO OLIVEIRA
  • JEFERSON DE SOUZA CAVALCANTE
  • MELQUISEDEC ABIARE DANTAS DE SANTANA
  • PAULO LEONARDO ARAÚJO DE GÓIS MORAIS
  • Data: 20-nov-2020


  • Resumen Espectáculo
  • The interest of science, and particularly of the fields of biology and neuroscience, is in understanding the functioning of the nervous system in relation to the products of brain activity, such as cognition and behavior, has led to the development of several investigations that put their focus of study in the frontal lobes, especially in the prefrontal regions. The dorsolateral, medial and orbito prefrontal cortex have been functionally studied; however, the anatomical projections of the axons and the description of the neural networks that originate in these areas of the brain have brought more interest in some than in others. With that being said, the medial region of the prefrontal lobes have not received sufficient attention in the approach and detail of its projections and relations with the subcortical structures of the brain, among which the tonsils and hippocampus are noted for having a functional relationship when considering the manifestations clinics of neurological and neuropsychological syndromes resulting from medial prefrontal cortex damage. Therefore, this research proposal is aimed to establish the neuroanatomic substrate of the cognitive and visceral-motor circuits of the prelimbic and infralimbic cortex of the medial prefrontal cortex and their projections and interactions with subcortical complexes in Callithrix Jacchus primate; delimited to areas and nucleus of the diencephalic, amygdaloid and hippocampus complexes. The research developed is presented as a comparative descriptive study, with non-probabilistic sampling, considering the use of the primate as an animal study model, of the species Callithrix Jacchus (known as Marmoset). As a technique to track nerve cells, the technique of axon marking, antegrade marking was used; deposited in the pre-limbic (PL) and infralimbic (IL) cortices. Among the planned hypotheses, it was proposed that there is an organized and exclusive distribution in the directionality of the fibers towards the subcortical regions associated with the three complexes of interest, in primates, a fact that was possible to corroborate from the results obtained. Most of the areas and nuclei of the diencephalic and amygdaloid complex received fibers of both cortices (PL and IL), and in the diencephalon, the four regions were reached from the PL, and the fibers of the IL were restricted to the thalamus and the epithalamus; in general, at different densities, but in the hippocampus complex the fibers were restricted to PL projections. It was also possible to determine the pattern of rostral-caudal distribution of the fibers in these areas, as well as to identify that the groups of fibers that come from the IL are more grouped within the complexes, than the groups that originate in the PL. These and other findings in this research stand out for their originality, as well as the pioneering methodological characteristics in achieving their objective; facts that, as a novelty, contribute to the study of the morphological correlates of the anatomical-functional activity in the brain.
8
  • ADRIANO CHIOMBACANGA NAFITAL
  • Influence of Temporal Sleep Allocation at Nights Before the Assessments on Academic Performance in Medical Students at the Federal University of Rio Grande do Norte
  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • LEANDRO LOURENÇÃO DUARTE
  • FELIPE BEIJAMINI
  • FERNANDO MAZZILLI LOUZADA
  • JANE CARLA DE SOUZA
  • JOHN FONTENELE ARAUJO
  • Data: 25-nov-2020


  • Resumen Espectáculo
  • The objective of this work is to study the influence of sleep temporal allocation at the nights before the assessments on the academic performance in medical students at the beginning of the course at UFRN - Central Campus. This is a cross-sectional study conducted in the semesters 2018.2, 2019.1 and 2019.2. Students filled out an identification form, answered the Morningness-Eveningness Questionnaire (MEQ), Munich ChronoType Questionnaire (MCTQ), Pittsburgh Sleep Quality Index (PSQI), Beck Depression Inventory (BDI) and the State-Trait Anxiety Inventory (STAI). For academic performance, the final grade of the discipline Biological Module II was used for students in the second semester and the final grade of the discipline Infectology for students in the fourth semester. The Kruskal Wallis test was used to assess the relationship of sleep temporal allocation at the nights before the assessments with academic performance, Horne and Östberg chronotype score, Social Jet Lag (SJL), PSQI score, BDI score, anxiety-state and trait anxiety scores. The research was approved by the UFRN Research Ethics Committee with opinion number: 2,996,461. Our results showed that the majority of the 201 students that participated in the study are male (62.2%), single (94.5%), with average age, body mass index (BMI) and academic performance of 21, 45 ± 3.47 years, 23.66 ± 3.67 and 7.41 ± 0.96 values respectively. Only 30.3% of students reported that they did not change their sleep routine at the nights before the assessments. The majority, 48.8% reported that they use the behavioral strategy of staying up late and sleeping a little before the assessments. Around 5% reported that they do not sleep before the assessments. We found a statistically significant difference between the groups according to the sleep temporal allocation at the nights before the assessments with academic performance [KW = 15.612 (4); p = 0.004], Horne and Östberg chronotype score [KW = 36.936 (4); p <0.01], PSQI score [KW = 22.213 (4); p <0.01], BDI score [KW = 19.358 (4); p = 0.001], anxiety-state score [KW = 23.316 (4); p <0.01] and trait anxiety score [KW = 16.883 (4); p = 0.002]. These results lead us to conclude that students who use a strategy of sleep temporal allocation at the night before the assessments that causes total or partial sleep deprivation have worse academic performance, tendency to evening-type, poor sleep quality and high scores of depression and anxiety. These findings reinforce the guidelines for students to have a study routine. In addition, it has a pedagogical implication in the sense of the need for the teacher to have a mechanism to follow the study routine and thus guide students.
9
  • MAYARA WENICE ALVES DE MEDEIROS
  • Black lives matter: studies about prosocial behavior of "pardo" and black brazilian children
  • Líder : MARIA EMILIA YAMAMOTO
  • MIEMBROS DE LA BANCA :
  • MARIA EMILIA YAMAMOTO
  • FIVIA DE ARAUJO LOPES
  • IZABEL AUGUSTA HAZIN PIRES
  • AIRI MACIAS SACCO
  • BRISEIDA DOGO DE RESENDE
  • Data: 17-dic-2020


  • Resumen Espectáculo
  • Prosociality, in the eyes of some evolution theorists, is seen as the key to understanding the success of humanity, being a factor found present from the first months of child development. The objective behind the present thesis is to investigate the effect of ethnic and social exclusion on prosocial behavior in Brazilian children. In order to achieve this goal, use was made of implicit and explicit measures. The first chapter brings a theoretical review of the theories of evolution that cover prosocial behavior, and which focus on the theory of cultural evolution. The second chapter is composed of a systematic review of studies that investigate the effects of priming on prosocial behavior in children. The third chapter comprises of three empirical studies that analyze, (1) the association between sharing and the racial identification of the child, (2) the effect of ethnicity in prosocial priming, and (3) the choice of a black or white character as friends. Our findings pointed to an association between the racial identification of the child and sharing; an increase in sharing under the condition with prosocial priming, regardless of racial bias; and the preference of a white character as a friend. The fourth chapter reports on the construction and validation of the Implicit Association Test for assessing prosociality in children (IAT-PSC). The test presented good internal consistency and a satisfactory validation of the items. The fifth chapter is comprised of two studies, in which the participants are children that reside in urban areas, rural zones and in quilombo communities. The results demonstrate greater sharing among urban children, but greater implicit prosocial preference among children from quilombo communities. When taken together, our studies suggest that ostracism, racial exclusion and group belonging are factors that influence prosocial behavior in children, both explicitly and implicitly.
10
  • MARIA LUIZA CRUZ DE OLIVEIRA
  • Effect of nighttime use of the cell phone on sleep-wake cycle, autonomic response and cognitive processing in college students

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • JOHN FONTENELE ARAUJO
  • JANE CARLA DE SOUZA
  • Minerva Aída García García
  • FERNANDO MAZZILLI LOUZADA
  • Data: 17-dic-2020


  • Resumen Espectáculo
  • The university experience promotes changes in the lives of emerging adults, among which greater use of media, whose proximity to the beginning of sleep causes irregularities in hours and sleep deprivation affecting basic cognitive processes that regulate performance, such as attention, working memory, inhibitory control, and cognitive flexibility. However, performance and sleepiness can suffer a compensatory effect from brain areas that can be reflected in cortical activation and autonomic activity. In this work, we assessed the impact of nighttime cell phone use on sleep irregularities and quality, social jet-lag, daytime sleepiness, and cognitive performance. In parallel, the compensatory effect of the autonomic nervous system to sleep deprivation was assessed through heart rate variability (HRV). 59 students (44 women) from higher education courses in the field of biosciences completed the questionnaire "Health and sleep" and the Epworth Sleepiness Scale. Then, they filled in the sleep diary, where they recorded their cell phone use after 6 pm, and used actimeters for 10 days. In this phase, they performed cognitive tests and collected variables of autonomic response once between 7 and 9 am. A GLM analysis was performed to see the effect of cell phone use after 6 pm on the other variables and 3 structural equation models to see the multiple prediction relationships between the study variables. In general, students slept and woke up earlier, with greater sleepiness on waking in the week and prevalence of excessive daytime sleepiness in the sample. The greater use of cell phones predicted greater daytime sleepiness (β = 0.016; p = 0.03) and HRV (β = 0.460; p = 0.001), as well as less sustained attention (β = 0.115; p = 0.063) and cognitive flexibility (β = -0.064; p = 0.008). The indirect impact of cell phone use after 6 pm on cognition was assessed using structural equation analysis, considering its action via sleep quality and irregularity, as well as changes in HRV and EEG. However, no indirect effects of cell phone use on cognitive variables were found. Therefore, cell phone use after 6 pm was associated with an increase in daytime sleepiness with negative impacts on sustained attention and cognitive flexibility in the morning in university students. Also, cell phone use was associated with increased HRV, which may be related to a compensatory effect of the parasympathetic nervous system to sleep deprivation.
11
  • JAQUELINNE PINHEIRO DA SILVA
  • Behavioral consequences of premature alcohol exposure in zebrafish

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • VANESSA DE PAULA SOARES RACHETTI
  • MONICA GOMES LIMA MAXIMINO
  • DIOGO LOSCH DE OLIVEIRA
  • ROSANE SOUZA DA SILVA
  • Data: 18-dic-2020


  • Resumen Espectáculo
  • Alcohol is a legal drug of great social acceptance and the impacts of its excessive consumption are targets of concern in the last decades. One of the main damages associated with the use of alcoholic beverages is its consumption by pregnant women. Exposure to alcohol during the prenatal phase compromises the function of the placenta and the fetus development, which can lead to fetal alcohol spectrum disorders (FASD), responsible for morphological, sensory, and cognitive abnormalities. Many studies have sought to identify the mechanisms of action of this substance at the cellular level and, due to limitations in studies with humans, many research use alternative animal models, such as the zebrafish (Danio rerio). Although recent research has explored this vertebrate as a model for alcoholic exposure during development, these studies are mainly focused on embryonic morphological malformations, with a gap in the knowledge of possible behavioral and cognitive deficits in individuals who do not have visible physical deformities. Thus, this thesis aimed to investigate whether early exposure to moderate doses of alcohol can cause behavioral or cognitive alterations, and especially, whether these signals would be detected at early stages of life. For this, we (1) characterized the embryonic development of zebrafish under different doses of alcohol; (2) investigated behavioral changes in zebrafish larvae under the context of a novel tank and inhibitory avoidance; (3) analyzed behavioral and neuronal effects of alcohol exposure at different embryonic stages memory, examining the levels of cell death at each stage; and (4) evaluated the effects of embryonic alcohol exposure on place preference, in fry and adult zebrafish. Our results showed that in addition to the alcohol concentration used and the embryonic stage in which animals were exposed, the effect of alcohol also depends on the particular behavior that is being observed, requiring multidisciplinary analyzes. We observed that behavioral indicators of FASD can be detected at very early ages and could be useful to the precoce diagnosis of the disorder. Also, we confirm the versatility of zebrafish as an animal model for studies of behavior and pharmacology, and especially of development, since this model facilitated scientific approaches that would be more difficult to be developed in mammalian models.

2019
Disertaciones
1
  • RAISSA NOBREGA DE ALMEIDA
  • Modulation of serum Brain Neurotrophic Factor by Ayahuasca: contributions to Major Depression

  • Líder : NICOLE LEITE GALVAO COELHO
  • MIEMBROS DE LA BANCA :
  • JAIME EDUARDO CECILIO HALLAK
  • MARIO ANDRE LEOCADIO MIGUEL
  • NICOLE LEITE GALVAO COELHO
  • Data: 18-ene-2019


  • Resumen Espectáculo
  • The Major Depression (MD) reaches about 300 million people of all age, totalizing 5% of the world population. American projections suggest a cumulative incidence of DM of 13.6% among men and 36.1% among women, aged between 12 and 17 years. In addition, 30% to 40% of patients do not respond to treatment. Recently, a double-blind, placebo-controlled randomized clinical trial (CT) showed that ayahuasca, a psychedelic tea from Amazonian, induced rapid antidepressant effects in patients with treatment-resistant MD. A clinical response was observed 24 hours after it ingestion, with effects statistically different from placebo 7 days post dose. In order to better understand the antidepressant action of ayahuasca, this study investigated the serum levels of brain-derived neurotrophic factor (BDNF) in the same sample of this CT, healthy control volunteers (M = 20, W = 25) and MD patients (M = 7, W = 21), before and 48 hours (D2) after ingestion of a single dose of ayahuasca (AYA) or placebo (PLA), in order to associate possible changes in BDNF with depressive symptoms and plasma cortisol. The research was approved by the Ethics Committee in Medical Research of the University Hospital Onofre Lopes (process nº 579.479) and registered as clinical trial no. NCT02914769. All blood collections were performed around 7:00 a.m. in order to avoid circadian variations. Prior to administration of AYA / PLA, we found similar serum BDNF levels between patients (P) and controls (C). However, we detected lower levels of BDNF in a subgroup of volunteers (P and C) who presented hypocortisolemia (n = 31), compared to those with eucortisolemia (n = 38). Moreover, was observed a negative correlation between BDNF and cortisol in these volunteers with eucortisolemia. After treatment (D2) we observed higher levels of BDNF in volunteers (P and C) who ingested AYA (n = 35) when compared to PLA (n = 34). In addition, only patients treated with AYA (n = 14), and not with PLA (n = 14), had a significant negative correlation between serum BDNF levels and depressive symptoms measured by the Depression Scale of Montgomery-Asberg (MADRS). Few CT evaluated serum BDNF levels in patients in response to antidepressant treatments and their results are inconclusive. This is the first double-blind, randomized, placebo-controlled CT to investigate the relation of BDNF and the clinical response of patients with depression after treatment with psychedelic that shows antidepressant potential. We observed a relationship between BDNF and cortisol that corroborates the current literature. In addition, the results suggest a link between ayahuasca-induced antidepressant effects and serum BDNF. Thus, this study contributes with an emerging view of the use of psychedelic drugs in the treatment of treatment-resistant DM, as well as the relationship between BDNF and the drug-induced antidepressant effect for DM treatment.

2
  • LETÍCIA AURORA COELHO DA SILVA
  • Comparison of cetacean detection during seismic surveys activities by three methods and from two monitoring platforms.

  • Líder : RENATA SANTORO DE SOUSA LIMA
  • MIEMBROS DE LA BANCA :
  • RENATA SANTORO DE SOUSA LIMA
  • ANDRÉ SILVA BARRETO
  • CRISTIANO LEITE PARENTE
  • Data: 25-feb-2019


  • Resumen Espectáculo
  • One of the most intense anthropogenic noises occurring in the oceans is caused by the explosions of air guns during seismic surveys. The highest energy levels produced by seismic surveys overlap the sound frequencies emitted by baleen whales, and most of their noise emissions are within the toothed whale's auditory range. As more research are being done and more information about the effects of seismic surveys on the marine biota has been investigated, Brazilian research should continue to contribute with scientific knowledge to improve the mitigation measures of these effects in our country. The first step to mitigate the effects of seismic surveys on cetaceans is the detection of these animals during this activity. The detection of cetaceans involves monitoring the oceans in two ways: a) visual monitoring; and b) passive acoustic monitoring (PAM). Were used as independent platforms of simultaneous monitoring, the traditional monitoring platform (TMP), the seismic vessel itself; and the alternative monitoring platform (AMP), the support vessel supporting the seismic vessel. The main goal of this study is to analyze the acoustic detections recorded during seismic survey activities, by the comparison of the methods of sampling effort (MSE) punctual and continuous, and between the TMP and AMP; and, b) to compare the visual detections recorded between TMP and AMP. The specific objectives of this research are: a) to verify if there is difference in the number of acoustic detections per hour, between the punctual MSE, in comparison to the continuous MSE; b) to verify if there is a difference in the highest values detected per hour of acoustic sampling effort between TMP and AMP; and, c) to verify if there is a difference in the number of visual detections recorded by the TMP in comparison with the AMP. A significant difference was found in the acoustic detection between the MSE and in the acoustic detections of higher values between the platforms, with the addition of the unidentified signal. But no significant difference was found between the acoustic detections of higher values between the platforms, without the unidentified signal and in the number of visual detections between the platforms. Here, we demonstrated the potential for cetacean detection that different methods and platforms have. Further research should be done prioritizing the standardization and union of cetacean monitoring and detection methods, so that we can detect them more efficiently and better identify the effects of seismic prospecting in each group.

3
  • FELIPE HAEBERLIN
  • Some more alike than others: personality influences on social relationships of captive capuchin monkeys (Sapajus sp.)

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • PATRICIA IZAR
  • RENATA GONCALVES FERREIRA
  • Data: 08-mar-2019


  • Resumen Espectáculo
  • In social context factors like age, sex, kinship and rank influence the quality of relationships between individuals. Beyond these factors, recent studies are showing the influence of individual differences on quality of relationships in animals. Similarities in personality dimensions like Openness, Sociability and Neuroticism can influence quality of relationships between individuals in dyadic and group levels. Given their enlarged neocortex and their behavioral complexity, capuchin monkeys are considered excellent translational models. The present work analyzed the influence of personality on social relationships in captive capuchin monkeys (Sapajus sp.). In dyadic level, results shown that similarity in higher Sociability, Openness and Assertiveness is related increased affiliation and better relationship quality while high Neuroticism related with increased agonism. At group level, high Sociability and Openness also relates to better general relationship quality. The present result refine the available information showing that not only similarities, but similarities in high values in personality traits influence social relationships. The results regarding Assertiveness, affiliation and relationship quality suggest a new perspective to this dimension besides the reported increased agonism, which was more influences by Neuroticism At group level we found and expansion to the pattern   found in dyadic level. However, this related to only two dimensions, indicating that social structure is more than the simple sum of dyadic relationships.

4
  • RODRIGO DE MENEZES GOMES
  • Sexual Strategies and Mate Choice in Transgenders

  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • VICTOR KENJI MEDEIROS SHIRAMIZU
  • WALLISEN TADASHI HATTORI
  • Data: 25-mar-2019


  • Resumen Espectáculo
  • Several researches on the intersexual differences of human sexual strategies and mate choice criteria have been made over the last decades, resulting in empirical data supporting the theories that have explained the evolution of human sexual and reproductive behavior, such as Sexual Strategies Theory (SST), Strategic Pluralism Theory (SPT) and Biological Market Theory (BMT). In general, these studies have focused on heterosexual individuals because hypotheses and predictions from explanatory theories of sexual strategies focus on their consequences in terms of reproductive success. Though many recent researches have also been performed with samples of homosexual individuals, pointing largely towards sex-typical behavioral strategies regardless of sexual orientation, the transgender phenomenon still remains relatively absent from investigations on human sexual strategies. This study aimed to assess and compare indicative and moderating variables related to sexual strategies and mate choice criteria in a sample of 120 individuals composed by 27 male-to-female (MtF) transgenders, 24 female-to-male (FtM) transgenders, 37 female cisgenders (F) and 32 male cisgenders (M). It was investigated whether either biological sex or gender self-perception was more influent on transgenders’ measures of sociosexuality (SS), mate value self-assessment (MVS), self-esteem (SE) and preferred characteristics for both short- and long-term mates. Statistical analysis of the obtained data indicated that, for sexual strategies deemed as more advantageous from an evolutionary standpoint (short-term for males and long-term for females), transgenders’ mate preference criteria were concordant with their biological sex. For the less advantageous strategies (long-term for males and short-term for females), however, the data pointed towards a likely influence of gender self-perception on mate preference criteria. Transgenders’ MVS measures were also congruent with their gender self-perception, whereas SS ones were mostly sex-typical. No statistically significant differences were found for SE measures. In sum, the study’s findings largely corroborated SST, SPT and BMT predictions, although both MtF and FtM transgenders had mixed patterns for what literature has established as being typical of each sex regarding the investigated variables.

5
  • THALLES DA SILVA PINTO
  • Environmental complexity: Effects on learning and aggressiveness of the Dusky Damselfish(Stegastes fuscus)

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • ANTOINE LEDUC
  • CARLOS EDUARDO ROCHA DUARTE ALENCAR
  • Data: 25-mar-2019


  • Resumen Espectáculo
  • Dusky damselfish (Stegastes fuscus) is a reef fish endemic to Brazil that occurs from the coast of the RN to SC. This species presents a strong agonistic behavior in defending your territory against intra and interspecific animals that transit or compete for resources, being considered a "key-specie" in the reefs in which it occurs. S. fuscus plays a strong role in regulating the agonistic relationships among the various species that make up the reef community. Due to the high anthropogenic impact the reef environments have been modified in terms of temperature, pH, oxygen and structural complexity. Research that relates changes in temperature and habitat structure of animals with behavioral and learning alterations can help to understanding the ecological consequences of these impacts and suggest more effective conservation alternatives. This study aimed to better understanding how global climate change can influence changes in the agressiveness, territoriality and learning of S. fuscus. The objective of this work was to test if the environmental complexity and water temperature influence the learning and aggressiveness of S. fuscus. All animals were collected on Pirambúzios Beach, transferred to the laboratory and placed in stock tanks. For experiment 1, animals were divided into: EE group (n=11) habitat consisting of an tank with bottom and walls covered with gravel substrate adhesive, shelter and artificial plant and group "BE" (n=09) habitat consisting of an tank without additional items. After 34 days under these conditions, time spent in each area and latency to reach the target area were quantified. For experiment 2, beyond to the complexity levels, there was also a temperature regime, as follows: Group "28B" (n=09) barren habitat at 28ºC, "28C" group (n=12), complex habitat at 28°C, group "34B" (n=09) barren habitat at 34°C and group "34C" (n=06) complex habitat at 34°C. After 30 days under these conditions, animals were submitted to mirror test, being filmed before (5min) and after (5min) exposure to the mirror, being verified swimming velocity, immobility time, time spent in each quadrants and frequency of agonistic displays in the two moments. Our results suggest that, in a future scenario, S. fuscus will have higher energetic costs caused not only by increase of temperature but also by physiological changes and its behavioral pattern.

6
  • EMANUELLE SILVA PEREIRA
  • Relationship between the level of knowledge about sleep and habits and quality of sleep, and the components of attention of colleges students

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • FERNANDO MAZZILLI LOUZADA
  • MARIO ANDRE LEOCADIO MIGUEL
  • Data: 26-mar-2019


  • Resumen Espectáculo
  • The delayed sleep phase, characterized by later sleeping and waking hours, seen in adolescence may persist after the youths' entry into university. In this context, many students use stimulants to minimize the effects of daytime sleepiness generated by chronic partial sleep deprivation on week schooling. This behavior can modify the habits and quality of sleep and thus, cause damage in the attention of those of the morning shift. Knowing that attention is a basic process capable of interfering in cognitive processes and that knowledge acts in decision making, we investigate the relationship between the level of knowledge about sleep and habits and the quality of sleep, and the components of attention young people from an RN public university. The 35 participants (19.8 ± 1.9 years old - 27 women and 8 men) answered the questionnaires: Health and Sleep, Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Morningness-Eveningness Questionnaire & Östberg; filled out the Sleep Diary and used an actiwatch for 10 days, and performed a Continuous Execution Task. Overall, G2 reported better sleep habits when compared to G1, such as: lower cell phone use and higher frequency of spontaneously arouse on school days, lower caffeine intake before sleep and less irregularity in total sleep time. Regardless of the group, some sleep habits differed between school days and free days. The bed, sleep, wake-up and get up times occurred earlier in school days (Anova, p <0.05) and the total time in bed and sleep duration were shorter on school days (Anova, p <0.05). However, the number of awakenings after sleep onset was greater on the days off (Anova, p <0.05). The quality of sleep did not differ according to the knowledge about sleep whereas daytime sleepiness scores were negatively correlated with the number of correct sleep alternatives (r = -0.35, p <0.05). Daytime sleepiness was reported more frequently by G1 (X2, p <0.05) who tended to have higher means of sleepiness scores (Mann-Whitney, p <0.05). At wake-up time, the sleepiness differed only between class and free days (Anova, p <0.05). The performance in the task that evaluates the four components of attention differed from that expected, since there was no relationship between performance and sleep knowledge. Most indicators and components of attention did not differ. There was only a tendency for G2 to present a reduction in the percentage of correct responses throughout the task (Anova, p = 0.09), suggesting a trend towards less sustained attention. Therefore, it is suggested that knowledge about sleep is related to the practice of better sleep habits and lower diurnal sleepiness. However, no relationship was observed regarding knowledge, sleep quality and performance in the attention task. Therefore, it is necessary to expand the sample to clarify the relationship between the level of knowledge about sleep and sleep habits and quality, and the components of attention of college students.

7
  • LUIZ GUILHERME MESQUITA PINHEIRO
  •  Morphophysiological correlates of personality in rescued capuchin monkey (sapajus sp.)

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • PATRICIA IZAR
  • RENATA GONCALVES FERREIRA
  • Data: 26-mar-2019


  • Resumen Espectáculo
  • Personality can be defined as stable differences in the behavioral pattern among individuals of the same population and it has been recorded in several animal species. One aspect of increasing research concerns the relationships of morphological and physiological variables to personality. In this work we investigated the relationship of characteristics such as face, weight, size, teeth and cortisol with the personality measured by 3 different methods: behavioral observation, behavioral tests and questionnaires, in a sample of 42 rescued monkeys (Sapajus spp). Based on the literature, we test the following hypotheses: 1) animals with a larger face are more assertive; 2) animals with a higher baseline level of cortisol are more explorative. To verify such relationships we created regression models that were selected by the Akaike information criterion. The analyzes revealed positive relationships between the face and curiosity, aggressiveness to strangers and in-group affiliative social behavior. Canine size and body length positively influence traits such as openness, feeding, positive social and locomotion. Cortisol negatively influenced assertiveness and sociability, and positively exploration and locomotion. The pattern found is discussed in light of the different methodologies used and the altered growth environment of the sample studied.

8
  • Ana Cecília Correia Santos das Chagas
  • Living in the crowd: Influence of density and social factors on cortisol levels in captive capuchin monkeys (Sapajus libidinosus)

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • RENATA GONCALVES FERREIRA
  • NICOLE LEITE GALVAO COELHO
  • PATRICIA IZAR
  • Data: 26-mar-2019


  • Resumen Espectáculo
  • Captive animals must cope with chronic stressors in their lives, from reduced and altered space to lack of scape areas. Capuchin monkeys (Sapajus spp.) are detached models to study effects of life in captivity, not only due to their prevalence in Brazilian rescue centers and Zoos, but also because of their detached behavioural flexibility, which made it possible for them to adapt to different natural environments such as the Atlantic forest and the Caatinga. This thesis uses behavioural and physiological (fecal glucocorticoid metabolics - FMG) measures in capuchin monkeys (Sapajus libidinosus) from different captive environments (CETAS at Natal/RN and Cabedelo/PB, and zoo at João Pessoa/PB) to test the hypotheses that social crowding, visitor presence and high hierarchical position are factors that increase stress levels, while social grooming and sexual behaviour decreases stress levels. In the first chapter, we explain the concept of stress, allostatic load and how it is affected by the environmental and social factors we will to analyze. Selecting regression models based on Akaike Information Criteria, our analyses corroborated the hypotheses that social crowding is a strong stressor to capuchins as revealed by increased mean, median and maximum FMG levels, however, presence of visitor was not a strong predictor of cortisol levels. As expected, dominant individuals were more stressed than subordinates. Contrary to expected grooming was not a strong predictor of decreased cortisol levels, but "sexual behaviour", "retreat", "proximity", "self-grooming" were. In conjunct these results indicate that despite increased vigilance in zoos, crowding is a stronger stressor to captive capuchin monkeys, and animals use an avoidance strategy, proximity and sex to cope with challenges of social life in captivity.

9
  • LUZIA ELIONAIDE ALBUQUERQUE MARTINS
  • Evaluation of food neophobia in twins

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • ALEXANDRE COELHO SERQUIZ
  • FIVIA DE ARAUJO LOPES
  • SANCHA HELENA DE LIMA VALE
  • Data: 26-mar-2019


  • Resumen Espectáculo
  • The food behavior refers to the attitudes related to the dietary practices of the individual and can act to promote the alimentary habit. There are some behavioral reactions that can increase or restrict food consumption. Food neophobia is characterized by the individual resistance to try a new food that can interfere in the nutritional balance, impacting the body composition. The relationship between genetic and environmental factors provides important clues to accounting for individual differences, especially in relation to the food choice process and the study with twins makes it possible to observe these factors. Thus, the objective of this study was to investigate the role of the degree of genetic proximity on the similarity in the neophobic response and its possible correlation with the body composition and zygosity. This research is composed of two cross-sectional descriptive studies. In Study 1, 138 adult subjects, both sexes, were submitted to the application of the Food Neophobia Scale (ENA) and anthropometric measurements and body composition measurements. In Study 2 the sample consisted of 138 adult individuals, both sexes, divided into 3 groups: monozygotic twins (MZ), dizygotic twins (DZ) and non-twin siblings (NG) with age difference of up to three years, who answered the Food Neophobia Scale (ENA). The results of Study 1 showed that dietary neophobia does not correlate with the measures for body composition analyzed in our study, BMI, lean mass and fat mass. In Study 2 the results showed a tendency for differentiation between groups, but not statistically significant. The results pointed to a heritability index of 29% for food neophobia classified as moderate mild. These findings become relevant for the understanding of the response of food neophobia and open important ways for its impact not only on body composition, but also on diet composition and on people's eating habits, as it can be reflected in several food decisions.

10
  • MARIA GABRIELA NOBRE MEDEIROS E SILVA
  • Psychological aspects in male infertility and its relationship with seminar parameters

  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • DIEGO MACEDO GONCALVES
  • Data: 27-mar-2019


  • Resumen Espectáculo
  • Conjugal infertility is a disease of the reproductive system that occurs in couples trying to conceive for at least twelve months without any contraception and without success. Male infertility may be related to the reduction of seminal quality and was related to numerous factors, whether physiological or even psychological. This research sought the relationship between seminal quality parameters and psychological aspects such as fertility adjustment, relationship satisfaction, self-esteem and the dimensions of self-perception of mate value in men seeking treatment for infertility at the Assisted Reproduction Center of the Maternity-School Januário Cicco in Rio Grande do Norte, Brazil. A total of 135 men filled up the research questionnaires and collected semen samples in the institution. The correlation between the spermogram values and the psychometric scales was performed to test three hypotheses: if there is a relation between seminal quality and psychological aspects; If there are differences between men who already have children and men who do not; if there are differences between men who know to have a male factor as the cause of infertility and men who do not know? A correlation was found between seminal volume and the sociability’s dimension, and also between progressive sperm motility and appearance’s dimension. Men who have children scored more in the relationship’s dimension. Men who did not have a diagnosis of male factor of infertility presented a higher score in two dimensions, view of the opposite sex and relationship. We conclude that there is a relation between the results obtained in the seminal analyzes and the psychological reality experienced by infertile men, more evident for the man who has a diagnosis of a male factor. We understand that neither the cause of infertility or the fact that the man has already had children has shown to be relevant to his fertility adjustment, his self-esteem and his satisfaction in the relationship. The greater impact of coping with the disease is the self-perception of mate value’s dimensions, of how the man sees and feels in relation to the opposite sex.

11
  • CAMILA PORTO BAUCHWITZ
  •  Sex, health, career success or birth order: What factors influence parental favoritism?

  • Líder : FELIPE NALON CASTRO
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • ANTHONIETA LOOMAN MAFRA
  • Data: 27-mar-2019


  • Resumen Espectáculo
  • In their life cycle, living beings want to transmit their genes to future generations, so reproduction is a fundamental step for transmission to occur. As part of the reproductive strategy, the parents of many species provide the necessary care to increase the chances of survival and reproductive success of the offspring, but alternatively they could also initiate another reproductive event. Therefore it is expected that those individuals who optimize energy expenditure will be selected by investing in the offspring who appear to have the highest reproductive return and so they can invest more readily in a future offspring. The parents are probably influenced by factors that contribute to increase the reproductive value of their offspring and thus invest in the higher value, saving energy, a concept called parental favoritism. This study tried to understand which factors influence the parents in favoring one child in front of the others. Through the literature, four factors have been selected that can influence the decisions of the parents: the physical and mental health of the children, the sex of the children with the highest reproductive value, the birth order effect and the professional success perspective of each son. We consider that these factors interfere in the reproductive success of the individual and, therefore, the parents would be expected to perceive and invest more in that son with more advantages before the brothers. Two hundred and twenty people participated: eighty-two parents of three children and one hundred and thirty-eight parents of two children. Significant results were observed in the relation of the prospect of career success with the favoritism of the parents in the group of parents of three children. Parents have invested more in their children who have had greater prospects for career success, demonstrating that the prospect of greater career success has an influence on parents when it comes to favoring one of their children. The study proved to be innovative by using a task to measure favoritism and by measuring career success to investigate parental preference. Modifications are necessary for the study to be able to evaluate parents with more children and it would be interesting to test other variables, such as attachment and parent-child personality.

12
  • SARAH SOPHIA GUEDES LINHARES
  • Behavioral and neurochemical evaluation of components of the timing system in male and female Wistar rats exposed to perinatal treatment with fluoxetine

  • Líder : JEFERSON DE SOUZA CAVALCANTE
  • MIEMBROS DE LA BANCA :
  • JEFERSON DE SOUZA CAVALCANTE
  • NICOLE LEITE GALVAO COELHO
  • EZEQUIEL BATISTA DO NASCIMENTO
  • Data: 28-mar-2019


  • Resumen Espectáculo
  • Selective serotonin reuptake inhibitors (SSRIs) are most commonly prescribed psychotropic drug during pregnancy and lactation. In this sense, it exposes mothers and infant brain to up modulatory and trophic effects of serotonergic neurotransmission. The serotonin promotes fundamental changes across development which include neuron migration, differentiation and organization of brain circuitry related to emotional, cognitive and circadian behavior. Early exposure to the selective serotonin reuptake inhibitors (SSRIs) induce long-lasting effects on behavioral and neural signalization of rodents. These effects include increased anxiety and depression-like behavior in adulthood and also aberrant neural circuit formation during lifespan. However, the long-term effects of early exposure to antidepressant over circadian rhythms and their neurochemical markers remain unclear. In this study, we tested the locomotor activity-rest rhythm, anxiety-memory performance and chemical oscillatory markers of the circadian system (neuropeptide Y and serotonin) at two zeitgebers (ZT6 and ZT18) in male and female offspring rats early exposed (developmental period GD13-GD21) to fluoxetine (20mg/kg). First, we carry out daily records of the locomotor activity-rest rhythm using activity sensors coupled to individual cages over four weeks. Then, we tested the anxiety-trace and memory behaviour using the open field chamber (OF) and discriminative avoidance (DA) paradigms. We lastly identify the neuropeptide Y (NPY) expression labelling both suprachiasmatic nucleus and intergeniculate leaflet (IGL), and as well the serotonin (5-HT) expression in the dorsal and medial raphe nuclei. In summary our results showed (1) perinatal fluoxetine affect anxiety and memory behaviour only in female rats (2) perinatal fluoxetine affect NPY and 5-HT expression and phase entrainment of locomotor circadian rhythm at ZT6 and ZT18 more in male than female offspring. Our data concur with previous reports had been showing that perinatal fluoxetine treatment do not elicit anxiety-trace and memory deficits in male rats although we have shown differential effects in females. The sexual differences induced by early exposure to fluoxetine on both locomotor circadian rhythm abnormalities and neurochemical expression are an important highlight of present work. Here, we show that male rats are more susceptible of phase entrainment and the NPY and 5-HT mis-expression compared to female rats. Thus, our results may helpful to a better knowledge about neurobiological mechanisms of circadian rhythms and relevant to understand the “broken brains” and behavioural abnormalities of offspring early exposed to antidepressants.

13
  • LARA GOMES DE SOUZA SILVEIRA
  • Empathy and recognition of emotions in childhood

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • ADRIANE XAVIER ARTECHE
  • FIVIA DE ARAUJO LOPES
  • MONIQUE BEZERRA PAZ LEITÃO
  • Data: 28-mar-2019


  • Resumen Espectáculo
  • Emotions can be a factor of improvement in social interactions. Expressing emotions brings an informational burden both to the individual who expresses them and to the individual who perceives them, and this creates a relationship between them, which is the basis of social interaction. For humans, the first established emotional relationship occurs between the baby and his or her primary caregiver. It is in this first relation that there is the development of what we call empathy, an emotional and behavioral perception before the emotions of the other. Empathy is a social skill that has its intricate roots with emotional attachments and the ability to relate to others. Thus, an inclusive, affective family background with authoritative parents end up favoring empathic abilities. The main objective of this work was to understand the development of empathy and the perception of emotions in childhood. This research is composed by four articles, two theoretical articles and two empirical articles. Theoretical articles addressed the topics emotions and empathy and were made from bibliographic documentary research. The empirical articles were collected in the city of Natal, Rio Grande do Norte, Brazil. For the empirical study on emotions we had a total sample of 153 participants, divided into three age groups (1: 5 and 6 years, group 2: 7 and 8 years and group 3: 9 and 10 years), of both sexes, students from a municipal school and a private school. The collection was performed individually and the children performed an emotion perception test, performed through a computer, in which they were presented three images of individuals expressing each of the six basic emotions so that the emotion could be identified. For the empirical article on empathy, we used two questionnaires guided with the children and a questionnaire was sent to parents to respond to their children's empathy (n = 306). It was observed that the child's age influences the ability to recognize emotions, unlike the gender that, in children belonging to the same age group, does not influence the perception of emotions. The results showed that there is no influence of the sex of the child on empathy in any of the three groups, however, that age is an important factor in children's empathic ability. It has also been observed that parents can not correctly perceive how empathetic their children are. Our findings bring a greater understanding of the role of emotion recognition and empathy throughout childhood, as well as the social role that the two abilities - which are intrinsically related - exert in the child and in its surroundings.

14
  • MARÍLIA FERNANDES ERICKSON
  • Floral Syndromes through pollinators eyes

  • Líder : DANIEL MARQUES DE ALMEIDA PESSOA
  • MIEMBROS DE LA BANCA :
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • FELIPE MALHEIROS GAWRYSZEWSKI
  • LEONARDO DE MELO VERSIEUX
  • Data: 27-may-2019


  • Resumen Espectáculo
  • Flower coloration is as beautiful and intriguing as the ecological and environmental factors behind them. Since the beginning of studies in floral biology, the question of the reasons behind floral coloration has been asked. Many authors have attributed flower colors to sexual selection and pollinator pressure. This is well exemplified by the idea of pollination syndromes: flowers with certain similar characteristics, such as color, are visited by similar groups of pollinators. Such a diverse array of coloration, however, is hardly ever explained by one factor alone. In this study, we aimed at understanding which environmental, ecological and physiological pressures are behind flower coloration, emphasizing, in testing, if flowers predicted by pollination syndromes are in fact conspicuous to their pollinators. We used Apis mellifera (honeybee), Drosophila melanogaster (housefly), Heliconius erato (butterfly) and Sephanoides sephanoides (hummingbird) as models to study how different pollinators see flowers. Flowers were more conspicuous to tetrachromat (housefly, female butterfly and hummingbird) than to trichromat (honeybee and male butterfly) pollinators. Coloration of Flowers is obtained mainly by pigments, that beyond the function of attracting pollinators have a role as chemical defense against herbivore and protection against solar radiation, among other things. Furthermore, plants are competing for pollinators, which might lead to divergence or convergence of floral color, depending on the environment. Even only taking pollination pressure into account, many animals have innate preferences for certain colors, and can easily learn how to associate color and rewards, which matters directly during foraging. Probably the interaction of all these factors have shaped the coloration of flowers across time, and pollination syndromes are a piece of the whole picture.

15
  • DIOGO JACKSON DE AQUINO SILVA
  • Visual communication in fiddler crabs: the influence of colors in the socio-sexual context

  • Líder : DANIEL MARQUES DE ALMEIDA PESSOA
  • MIEMBROS DE LA BANCA :
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • FELIPE MALHEIROS GAWRYSZEWSKI
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • Data: 29-may-2019


  • Resumen Espectáculo
  • The process of animal communication influences how individuals find food, perceive predators, recognize their conspecifics, and select reproductive partners. Fidler crabs are strongly influenced by intra and intersexual selection; they can communicate visually by having their chela, size, ornament building and body coloration. Studies regarding body coloration, however, are restricted only to one species, endemic to Australia. Considering the richness in spices fiddler crabs have all around the planet, the need for more studies, especially in phylogenetically different groups, is evident. In this work we reviewed how visual communication in fiddler crabs, and their different signals, can influence socio-sexual decisions in female and male crabs. We tested how body coloration of a fiddler crab species from the America (Leptuca leptodactyla) affects recognition of conspecifics and mate selection. For this, we studied female preference by presenting females with males with painted chela and/or carapace, so they would reflect hetero-specific or conspecific males. We verified that claw coloration is important for mate selection, and carapace colour is fundamental for inter-specific recognition. This is the first study evidencing that the coloration of the carapace in make fiddler crabs serve as a parameter for interspecific recognition in fiddler crabs.

16
  • SYLVIA LIMA DE SOUZA MEDEIROS
  • Behavioral evidence of a state analogous to REM sleep in octopuses (Octopus insularis and Octopus cf. vulgaris)

  • Líder : SIDARTA TOLLENDAL GOMES RIBEIRO
  • MIEMBROS DE LA BANCA :
  • SIDARTA TOLLENDAL GOMES RIBEIRO
  • JOHN FONTENELE ARAUJO
  • WILFREDO BLANCO FIGUEROLA
  • Data: 26-ago-2019


  • Resumen Espectáculo
  • Sleep is a behavior that occurs in several taxa of the animal kingdom, suggesting that sleep emerged primarily in the evolutionary chain of metazoans. Despite being a widely studied behavior in vertebrates, mainly mammals and birds, it is known that some invertebrates also present this quiescence state. Octopus is one of the invertebrates in which this behavior is expressed in a complex way, with electrophysiological records showing that brain activity increases when the animal is resting. However, these data were observed only in 4 Octopus vulgaris, due to technical challenges of conducting electrophysiological records in the aquatic environment that make this type of experiment difficult. However, sleep studies can be performed using the behavioral criteria used to identify this state in vertebrates. Thus, this work aimed to investigate, classify and describe in detail the quiescence states observed in Octopus insularis and Octopus cf. vulgaris through comprehensive behavioral quantification using video recordings. In addition, to assess potential differences in the arousal threshold of each state, O. insularis were exposed to visual and vibratory stimuli during each identified sleep-wake state. The results showed that O. insularis and O. cf. vulgaris have conspicuous behavioral variations during quiescence. Some of them have been cited in the literature, such as presenting half-and-half body pattern (QHH) and narrow or completely closed eye pupil (QCP). But other changes in the quiescent state have not been described yet: The change in body pattern to dark color (observed only in O. cf. vulgaris); one eye movement (QOEM) (observed in both species); and a REM-like sleep of vertebrates (QEMBPC) (observed only in O. insularis). In this last, occurs movement of both eyes while the animal changes the skin color and texture, accompanied by contractions of the body similar to muscular spasms and random movement of the suckers. The test to evaluate the arousal threshold of each state showed significant difference between the states, with the highest latency observed in the QEMBPC state, followed by the QPC, QHH and, finally, the alert, with the lowest arousal threshold. These results suggest the existence of different sleep states in the octopus, which makes the quiescence of this animal even more similar with the vertebrates sleep. For example, the "QCP" state appears to be analogous to slow wave sleep, while QEMBPC appears to be analogous to REM sleep. In addition, the QOEM state may be an evidence of uni-hemispheric sleep, which is an adaptation commonly observed in marine mammals and birds. Thus, this work suggests investigating whether, in addition to the behavioral similarities observed, the sleep of these cephalopods also have the same physiological functions that it performs in vertebrates. This will be possible with the improvement of techniques for conducting electrophysiology in the aquatic environment or without the use of wires, as well as by investigating immediate early genes that may be associated with the sleep of these animals.

17
  • EVERTON XAVIER DE LIMA
  • The man on streets: the relationships between risks, love and family from the evolutionary perspective.

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • FELIPE NALON CASTRO
  • ANTHONIETA LOOMAN MAFRA
  • Data: 27-ago-2019


  • Resumen Espectáculo
  • Reproductive behavior is an important factor in the evolution field. Starting from sexual strategies, we can analyze the repercussions of mate choices and what motivates them.
    Therefore, papers that seeks to understand the factors involved in this field and related environmental characteristics becomes really important. This paper has two studies as focus. From a center that serves homeless people, we obtained a sample of 136 homeless men. In the first study, a sociodemographic characterization of the male population was performed from homeless men in the city of Natal / RN. Our sample had a majority claiming single marital status, mean age 37.5 years, ie men approaching middle age. We also observed a predominance of time of four years or more on the street. The expressive use of chemical and illicit substances was one of the main results in the sample. In addition, most men reported the conception of short-term relationships up to six months and long term being from four years or more time. Finally, in study 2, we analyzed a relationship between anxious and avoidant attachment dimensions with risky behaviors and family unpredictability. We found out that as much as older they get, the lower is the avoidance of affective relationships, and also found out inversely proportional relationship between avoidance and anxiety. We also discovered positive correlation between unpredictability of resources and anxious attachment. The individuals were classified into risk groups, where it was possible to observe a predominance of high averages of anxiety levels related to higher risks. Finally, we hypothesized the possibility of mixed strategies related to sexual selection in homeless men. In summary, the present study demonstrates the importance of expanding responses on reproductive strategies in different groups and environmental situations involved.

18
  • MARIANA DA SILVA CAPÍTULO
  • Influence of color vision on fruit and insect detection in Callithrix jacchus groups in Caatinga

  • Líder : DANIEL MARQUES DE ALMEIDA PESSOA
  • MIEMBROS DE LA BANCA :
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • RENATA GONCALVES FERREIRA
  • ANDRE CARREIRA BRUINJÉ
  • Data: 29-ago-2019


  • Resumen Espectáculo
  • Primates have the ability to be trichromat, but this characteristic is quite variable. While in catarrhine monkeys males and females both have trichromatic vision, in platyrrhine there is color vision polymorphism, with occurrence of trichromat and dichromat females, while males are necessarily dichromat. Trichromacy is thought to be an adaptation to improve detection of ripe fruits and / or young leaves against a background of mature leaves. On the other hand, it has been suggested that dichromat individuals are better at finding camouflaged insects, whereas trichromatmas have the advantage of detecting conspicuous insects. Although there are several studies on color vision focused on visual modeling, experiments on semi-natural conditions and studies on nature, the results are inconsistent. Therefore, in this study we analyze if color vision influences the detection of fruits and insects in groups of Callithrix jacchus in Caatinga. For this, two groups of marmosets were followed from dawn until dusk and recorded the food items consumed. Fruit availability and arthropod abundance in the foraging area of marmoset groups was also evaluated. We used visual modeling to calculate the chromatic contrast (JND) between fruits and insects and their backgrounds for the six color vision phenotypes from field photographs. According to our work, the fruits found in Caatinga can be detected by the brightness and the green-red axis, while the insects can only be detected by the green-red axis, suggesting an advantage of the trichromats in the detection of both. the items. We have found that trichromat phenotypes have superior fruit detection performance as expected. As far as insect detection is concerned, although phenotype 543/562 outperforms, all phenotypes are equally able to detect insects. This is the second work on color vision carried out at Caatinga and the first visual modeling work that includes the two main food item types of the calithrichid diet.

19
  • KLEYTONE ALVES PEREIRA
  • Look at you! Evaluation of sociosexual color signaling in Artibeus planirostris (Mammalia - Chiroptera), the influence exercised by parasitism and preaction pressures

  • Líder : DANIEL MARQUES DE ALMEIDA PESSOA
  • MIEMBROS DE LA BANCA :
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • ARRILTON ARAUJO DE SOUZA
  • ANDRE CARREIRA BRUINJÉ
  • Data: 30-ago-2019


  • Resumen Espectáculo
  • Coloring is responsible in organisms for mediating the relationship between the individual and the environment in which they are inserted in important ways, including social signaling, anti-predation defense, parasitism, thermoregulation, protection against sunlight at wavelengths light in the range of ultraviolet, microbes and abrasion. To this end, several factors are associated with the production of colors in animals and, in addition, many factors are also associated with the perception of coloration expressed in the body of animals. Many factors can influence the way colors are expressed, either individually, such as parasitism, or evolutionarily, as pre-dation pressures. Thus, this paper aims to physically describe the coloration expressed on the coat of Artibeus planirostris and to know if parasite infection and predation pressure visually influence how this coloration is expressed. For this, the Artibeus planirostris stains were meas-ured in six body parts of different individuals, aiming to use the color obtained to visually model the way individuals at different times in the life history of the species see each other and com-pare how they were seen by the predator and the conspecific. In addition, the influence of par-asite infestation was tested to determine if there was a change in the expression of coat color. Our results showed that the Artibeus planirostris coat was visually perceived better by the owl than by the conspecific and that different aspects of the species biology are distinguished by the conspecific. We also show that parasite infestation influences the coloration expressed on the animals' coat, and is also distinguished by other individuals between parasitized and non-para-sitized animals. Our work is pioneering in information about the coloration of bats and espe-cially about how these animals see themselves and what are the relationships between this pa-rameter and interactions with predators, as well as the influence of parasitosis on coloration expressed in the coat of animals. This shows us how vast this area can be for studying the group's behavior and sensory ecology, opening up a huge range of opportunities for other re-searchers.

20
  • YVES MARTINS VARELA
  • Group Cognitive-Behavioral Therapy in the Treatment of Major Depressive Disorder

  • Líder : NICOLE LEITE GALVAO COELHO
  • MIEMBROS DE LA BANCA :
  • NICOLE LEITE GALVAO COELHO
  • FIVIA DE ARAUJO LOPES
  • MELYSSA KELLYANE CAVALCANTI GALDINO
  • Data: 30-ago-2019


  • Resumen Espectáculo
  • Major Depressive Disorder (MDD) is a mental disorder whose prevalence grows significantly with each generation, today affects more than 320 million people and is predicted that by 2030 it will be the first disabling cause for work. To elucidate the neurobiology underlying MDD is useful to understand this disorder , and is a service to the advancement of clinical practice focused on its identification and treatment. In this context, there are psychophysiological parameters with potential to be biomarkers of MDD, including cortisol and the sleep quality. Likewise, it is understood that, besides depressive symptoms, other psychological aspects are linked to the presence and course of MDD, being anxiety and self-esteem some of the main ones. Thus , this study, a clinical trial, aimed evaluating before and after monotherapy treatment using group Cognitive Behavioral Therapy( GCBT), cortisol (plasma and salivary) levels , anxious symptoms, self-esteem levels and sleep quality in depressed patients (n = 20; women n = 11), specifically college students. Prior to treatment, patients showed higher plasma cortisol levels than their healthy peers, the control group (n = 25; women n = 13), and higher salivary cortisol response on awakening and poor sleep quality. Patients responded to the intervention with decreased of depressive symptoms, and 55% of the m achieved remission. In addition, there was a reduction in anxious symptoms, increased of self-esteem and improved sleep quality; however, cortisol levels remained without significant variations. Still, it was noticed that self-esteem had a mediating effect and that cortisol had a moderating effect on the symptoms of depression, due to the remission of MDD. In view of these data, the efficacy of GCBT monotherapy in the treatment of patients with mild and moderate levels of MDD was observed, which surpassed remission rates of clinical trials with psychotherapy, pharmacotherapy, and combined use of both. Therefore, it is understood be relevant additional studies that investigate the GCBT and psychophysiological biomarkers in order to contribute to the solidification of precision psychiatry.

Tesis
1
  • SEBASTIAO PACHECO DUQUE NETO
  • Neuroanatomical Study of the Subparaventricular Zone (SPVZ) of the Marmoset (Callithrix jacchus): Cytoarchitecture, Neurochemical, and Retinal Projections Considerations, as well as its relationship with the Extended Circadian Rhythm System

  • Líder : JEFERSON DE SOUZA CAVALCANTE
  • MIEMBROS DE LA BANCA :
  • EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • JEFERSON DE SOUZA CAVALCANTE
  • JOSÉ RODOLFO LOPES DE PAIVA CAVALCANTI
  • MARIANA FERREIRA PEREIRA DE ARAUJO
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 21-feb-2019


  • Resumen Espectáculo
  • The circadian timing system (CTS) is composed of a set of neural structures responsible for the generation and modulation of the circadian rhythms. The suprachiasmatic nucleus (SCN) of the hypothalamus is the structure that generates the circadian rhythmicity, synchronizer with the 24h environmental light cycle. The SCN generates the expression of circadian rhythms in several diencephalic, telencephalic, and forebrain neural structures. Recently, has been proposed the concept of "extended circadian rhythm system", considering that there are almost 100 neural structures that could compose this system. Of the several regions involved in this context, the Subparaventricular Zone (SPVZ), the densest projects of the SCN, has been highlighted, although not yet studied, especially in primate species such as the Callithrix jacchus (marmoset). The objective of our study is to characterize its cytoarchitecture and neurochemical composition, and to map afferents from the retina in the SPVZ of the marmosets. We were able to identify the SPVZ cytoarchitecture in this species through the Nissl method and immunoreactivity for specific neuronal nuclear protein (NeuN), and glial fibrillary acidic protein (GFAP). We have identified the SPVZ located between the dorsal and caudal portions of the SCN, from its central level and retrochiasmatic region, and ventral portions of the hypothalamic paraventricular nucleus (PVN), distributing lateral to the third ventricle, occupying periventricular portions. The neurochemical content of calcium-binding proteins demonstrates a more pronounced presence of immunoreactive neurons for calbindin (CB) when compared to the few immunoreactive neurons for calretinin (CR) and non-marking for parvalbumin (PV). The CB immunoreactive neurons present a dorsolateral route, as well as the ventromedial, ventrolateral, and perisuprachiasmatic ventrolateral regions of SPVZ. It was also possible to observe in the ventromedial portion of SPVZ immunoreactive neural fibers to the neuropeptide Y (NPY), the enzyme decarboxylase of glutamic acid (GAD), and substance P (SP), whereas in the ventral and retrochiasmatic portions we observed immunoreactive 5-HT neuropil. The glutamate receptor subunit 1 (GluR1) is strongly present in the dorsal SPVZ. We also observed a bilateral distribution of axonal terminals of the immunoreactive retinohypothalamic tract (RHT) to the b subunit of the cholera toxin (CTb), which demonstrates retinal projection to the ventral and perisuprachiasmatic ventrolateral region, keeping topographic relationship with immunoreactive neurons for CB in this region. Although we did not perform functional experiments, the clear presence of CB in the marmoset SPVZ, and relationship with the SCN and PVN, together with the data available in the literature, places the marmoset SPVZ as an important region of the extended circadian rhythm system.

2
  • LUANE MARIA STAMATTO FERREIRA
  • The call of the (Neotropical) wild: maned wolf long-range acoustic ecology.

  • Líder : RENATA SANTORO DE SOUSA LIMA
  • MIEMBROS DE LA BANCA :
  • HOLGER KLINCK
  • JEFFREY EDWARD PODOS
  • JULIE ANNE PATRIS
  • RENATA SANTORO DE SOUSA LIMA
  • SUSAN PARKS
  • Data: 28-feb-2019


  • Resumen Espectáculo
  • Maned wolves are difficult to observe in the wild because of their low densities and of their cryptic and crepuscular-nocturnal habits. Exploring their long-range call – the roar-bark – is an efficient alternative to study the species. We used a combination of methodologies: we played back roar-barks in their natural habitat to test how free-ranging animals would respond and to understand the propagation properties of this vocalization in the wild; we recorded spontaneous roar-bark sequences of wild maned wolves through a grid of autonomous recorders for eight months to reveal long term temporal patterns; and we used captivity records to access gender and individuality in the roar-bark and test its application on natural recordings. We found that maned wolves vocalize more on the beginning of the night, and this was the only period we obtained responses during the playback experiment, despite dawn being the best propagation period for roar-bark transmission. Social factors may be influencing the timing of their long-range vocal activity. We suggest that roar-barks may be an honest advertisement of quality for territorial defense. Maned wolves vocalize more on better moonlit nights, especially when the first half of the night is illuminated, likely as a consequence of reduced foraging time and therefore having more time to invest in acoustic communication. It was possible to identify the mating and circa-parturition period in the natural recordings by an increase in solo and group vocal activity, which indicates a role of roar-barks in partner attraction/guarding and intra-familiar-group communication. In captivity, male roar-barks were distinguishable by their longer duration, also indicating a sexual function and suggesting a higher energy investment to advertise motivation. Roar-barks were also individually distinct. However, site characteristics, such as presence of vegetation, drastically affected both the propagation of broadcasted roar-barks and most identity and gender parameters’ transmission in the wild. Elevating the speaker 45° upward to simulate the head/muzzle position during vocalization lead to lower sound intensities, but partially counteracted the negative effects of vegetation on signal transmission. The few stable parameters were able to discriminate individuals, although with lower success rate. In wild recordings the variation of parameters due to propagation was larger than the variation due to individual differences limiting passive acoustic monitoring as a means of counting individuals in their natural habitats. Despite the present limitation of vocal identification in the wild, bioacoustics tools proved efficient in revealing the secretive behavior ecology of maned wolves.

3
  • PAULO LEONARDO ARAÚJO DE GÓIS MORAIS
  • Axonal architecture of the thalamic striatal connections in marmosets (Callithrix jacchus)

  • Líder : EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • MIEMBROS DE LA BANCA :
  • EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • FAUSTO PIERDONA GUZEN
  • FRANCISCO GILBERTO OLIVEIRA
  • JUDNEY CLEY CAVALCANTE
  • RUTHNALDO RODRIGUES MELO DE LIMA
  • Data: 11-mar-2019


  • Resumen Espectáculo
  • The basal ganglia are involved in motor control and learning and in executive functions, integrating cortical, thalamic and brainstem information. The striatum is the main gateway to this information, being organized into 2 compartments: matrix and striosome, structures with different neurochemical patterns and input-output projections. It is known that the caudal intralaminar nuclei (centromedian and parafascicular) promoves strong input to the striatum in primates. However, studies of projections from other nuclei are poorly documented. Therefore, we aim to describe and characterize quantitatively and qualitatively the thalamus-striatal projections in the commom marmoset (Callithrix jacchus). We used iontophoretic microinjections of BDA, an anterograde tracer, in the mediodorsal (MD), rostral intralaminar (IL) and medial pulvinar (PM) nuclei to study the axonal arborizations types of the thalamo-striatal neurons. We performed different histological staining procedures to delineate and identify structures (to delineate the nuclei, to identify the striatal compartments and to localize the deposits and the axons/varicosities). The striatal compartments were clearly distinguished, exhibiting a mosaic appearance. The matrix is strongly reactive for calbindin, parvalbumin and acetylcholinesterase histochemistry, while the striosome has low reactivity for all three markers. Type 1 arborization contains axons with varying length and thickness and varicosities of different sizes in passant, while type 2 has variable thickness, with many ramifications and display many short radiating dendrites studded with protrusions and grapelike appendages. The MP presented scarce and sparse projections in a large rostrocauldal extension of the striatum, with an important input to the tail of the caudate nucleusl, and type 1 arborization. The MD projects more focally and denser than the MP, and shows both types of afforestation. The projection from the IL was dense, with both types of arborization, mainly in the dorsolateral putamen, in a restrict rostrocaudal extension. All nuclei exhibited projections that preferentially reach the matrix. The varicosities of IL are significantly larger than those of MD and MP, and there are no differences in the sizes of the varicosities present in the matrix and the striosome.

4
  • DIANA ALINE NOGA MORAIS FERREIRA
  • Molecular mechanisms involved in reconsolidation of fear extinction

  • Líder : MARTIN PABLO CAMMAROTA
  • MIEMBROS DE LA BANCA :
  • ALESSANDRA MUSSI RIBEIRO
  • ANA CAROLINA LUCHIARI
  • DIEGO MONCADA
  • MARIO ANDRE LEOCADIO MIGUEL
  • MARTIN PABLO CAMMAROTA
  • Data: 15-mar-2019


  • Resumen Espectáculo
  • ReactiMemory reactivation can induce two apparently competing processes, namely extinction and reconsolidation. Extinction involves reduction of a previously acquired response to a stimulus through formation of a new memory trace. On the other hand, reconsolidation involves modification of a previously established memory trace, either for its strengthening or updating. Several studies discuss the opposition between extinction and reconsolidation, but little attention was given to a possible interaction between them. Previous work by our group has demonstrated that extinction memory is susceptible to reconsolidation in a BDNF-dependent manner. In the present work, we investigated the mechanisms involved in activation/expression of BDNF and the pathways it activates in CA1 region of dorsal hippocampus. We trained male Wistar rats in step-down inhibitory avoidance task, extinguished the aversive memory and performed pharmacological interventions before (Ro 25-6981) and/or after (rapamycin, BDNF, anti-BDNF, anisomycin, pep2m, Ro 25-6981, TCN-201) memory reactivation. In addition, we analyzed expression and phosphorylation of target molecules at different times after reactivation of extinction memory. As a result, we observed that rapamycin administration immediately, but not 6 h after reactivation, impairs reconsolidation of fear extinction, an effect reverted by BDNF co-infusion. In addition, we showed AMPARs trafficking is required for reconsolidation of fear extinction and BDNF is not able to reverse the amnesic effect of AMPARs trafficking blockade. Finally, we observed that NMDARs containing GluN2B participate in destabilization, while NMDARs containing GluN2A participate in trace restabilization during reconsolidation of fear extinction. Finally, our results suggest the existence of a mTOR-BDNF-AMPAR pathway that would act in the memory trace restabilization.

5
  • GIOVANNA WANDERLEY PETRUCCI TOSCANO
  • School bullying: Evolutionary understanding and cognitive-behavioral intervention

  • Líder : MARIA EMILIA YAMAMOTO
  • MIEMBROS DE LA BANCA :
  • MARIA EMILIA YAMAMOTO
  • FIVIA DE ARAUJO LOPES
  • IZABEL AUGUSTA HAZIN PIRES
  • MELYSSA KELLYANE CAVALCANTI GALDINO
  • SILVIA HELENA KOLLER
  • Data: 06-may-2019


  • Resumen Espectáculo
  • Bullying has been heavily investigated, but the results of anti-bullying programs are still unsatisfactory. Studies in the evolutionist perspective and different intervention programs have been developed with the purpose of amplifying these results. The present work has proposed to investigate possible contributions of Evolutionary Psychology to the understanding of school bullying as well as to develop a program of cognitive-behavioral intervention for its confrontation among adolescents. Five studies were carried out. The first was a systematic review of the literature on bullying in Evolutionary Psychology, in which where found nine empirical studies reviewed by peers in the databases: PsycINFO, PUBMED, Google Scholar, Index Psi, SciELO, LILACS and PePSIC. The second study performed procedures for adaptation and validation of the Bullying Participant Behaviors Questionnaire with a sample of 478 Brazilian adolescents. The third study compared indicators of mental health and perception of school climate among 240 adolescents, categorized in different roles in bullying. The fourth study evaluated the influence of third parties under different conditions on the cooperation frequency with a possible bullying victim using an adapted version of the prisoner's dilemma with 274 students. The fifth study presented the development, application and evaluation of a universal cognitive-behavioral intervention to reduce school bullying in 58 participants, using an evolutionary understanding of the phenomenon. The results showed that Evolutionary Psychology can broaden the understanding of school bullying by providing information articulable with the cognitive-behavioral intervention model, favoring the development of promising anti-bullying programs.

6
  • LUCIDIO CLEBESON DE OLIVEIRA
  • Analysis of the inoculation of mesenchymal stem cells in the presence of fibroblast growth factor 2 in the morphological and functional regeneration in Facial Nerve Fraction of Wistar rats

  • Líder : JEFERSON DE SOUZA CAVALCANTE
  • MIEMBROS DE LA BANCA :
  • JEFERSON DE SOUZA CAVALCANTE
  • EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • EUDES EULER DE SOUZA LUCENA
  • JOSÉ RODOLFO LOPES DE PAIVA CAVALCANTI
  • MARCO AURÉLIO DE MOURA FREIRE
  • Data: 07-jun-2019


  • Resumen Espectáculo
  • Studies have shown the influence of the environment on the growth of peripheral nervous system (PNS) injured nerve fibers, as well as the potential for stem cell (CT) use, associated or not with Fibroblast Growth Factor - 2 (FGF - 2), in make this environment more conducive to nerve regeneration. Thus, the study proposes to analyze the effect of the inoculation of mesenchymal CTs in combination or not with FGF-2, in promoting facial nerve regeneration. Wistar rats were submitted to facial nerve crushing in the vicinity of the post-auricular region and were treated or not with CT associated or not with FGF-2. Then, the behavioral evaluation of the animals was performed for 90 days, after which the facial nerve tissue analysis was performed through immunohistochemistry for the growth-associated protein 43 (GAP-43), for the nuclear neuronal protein (NeuN), for Protein glial fibrillary acid (GFAP) and for OX-42. The study showed the influence of the Stem Cells and FGF-2 on the behavior of the motor function of animals submitted to facial nerve injury, evidenced by the behavioral analysis. When comparing the four groups in the histological evaluation, these presented significant differences between them, when comparing the results, it was observed that the groups with CT administration and the CT group associated with FGF-2 and the FGF-2 group presented better results, considering that the Stem Cells groups associated with FGF-2 and FGF-2 groups showed a greater number of fibers, demonstrating a greater axonal budding, thus confirming the properties of FGF-2 in optimizing the differentiation of Stem Cells, as well as stimulate the regenerative process. In view of the results, it is evident that the use of stem cells and FGF-2 potentiated the regenerative process of the facial nerve, providing a more significant functional and histological recovery.

7
  • FABÍOLA RODRIGUES DE FRANÇA CAMPOS
  • MOTOR INJURIES OF CENTRAL AND PERIPHERAL ORIGIN INTERFEREM DIFFERENT IN ACURACY AND PRECISION OF TARGETS IN BIOLOGICAL TRAJECTORIES

  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • JOHN FONTENELE ARAUJO
  • KERSTIN ERIKA SCHMIDT
  • TANIA FERNANDES CAMPOS
  • ANTONIO PEREIRA JUNIOR
  • EDGARD MORYA
  • Data: 08-ago-2019


  • Resumen Espectáculo
  •  

    Several experimental results suggest that the perception and production of human movement share a common functional network of control in the brain. To study this perception-action interaction, we evaluated the precision and accuracy by conducting a behavioral test to determine targets in similar trajectories, but differed in relation to their velocity profiles: biological (B) and non-biological (NB). The volunteers were asked to estimate the end point of trajectories that had their last part occluded and that differed in relation to the movement: B and NB and direction: ascent (S) and descent (D). Thirty-six volunteers participated in the study: 13 healthy volunteers (M = 2 and F = 11, mean age 41,36 ± 12,91), 12 volunteers with Stroke (M = 6 and F = 6; 51,67 ± 10,13) and 11 volunteers with Peripheral Nerve Injury all males with a mean age of 33,64 ± 7,42. Estimated vector distance was calculated for each trial [DVE (Rn2 = Xn2 + Yn2)]. Precision was calculated by the median of the DVE and the accuracy of its dispersion (quartile 75). The results pointed to an interesting finding: the behavioral test was sensitive to point out differences between the biological and non-biological trajectories in the patient groups (stroke and LNP). Patients with stroke differed in the MSB trajectory (107,14mm) vs MSNB (164,68mm) (U = 7921; p = 0,001), showing a greater precision in the biological profile trajectory, whereas the LNP patients differed in the MDB trajectory (103,23mm) vs MDNB (78,20mm) (U = 7263; p = 0,019) and showed a greater precision in the non-biological profile trajectory. The group of healthy subjects had greater precision when compared to the other groups in all trajectories [X² = 348,06 (2); p <0,001]. Regarding accuracy, healthy individuals and patients with LNP behaved in a similar way and differed from stroke patients [healthy x stroke - X2 = 16,800 (3); p = 0,01] and [LNP x stroke - X2 = 12,774 (3); p = 0,005]. Using a mixed model it was found that healthy individuals are more exact (precision + accurate) than individuals with LNP and these are more exact than individuals with strokes. Exactitude was greater in detecting descent and biological movements. The results suggest loss of the perception-action coupling, individuals with motor injury may present losses in the biomechanical efficiency of the movement. The origin of the lesion (central or peripheral) seems to affect the recognition of biological movement.


8
  • UBALDO ENRIQUE RODRIGUEZ DE AVILA
  • SUSTAINABLE ATTENTION IN THE CLASSROOM: PERSONALITY, EMOTION AND CHRONOTYPE MODULATION

  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • JOHN FONTENELE ARAUJO
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • IVANISE CORTEZ DE SOUSA GUIMARAES
  • KATHIANE DOS SANTOS SANTANA
  • RAPHAEL BENDER CHAGAS LEITE
  • Data: 09-ago-2019


  • Resumen Espectáculo
  • Introduction: Attention is considered a psychological process that supports all cognition. To measure attention in a natural learning context (classroom), using objective and non-invasive methods, easy to use and with scientific rigor, to understand how it behaves over time and how it is modulated from the individual characteristics of the students, has become a challenge for teachers and researchers. Today it is known that the Sustained Attention (SA) can be measured by autonomic activity of Heart Rate Variability (HRV). Objectives: To design and validate an SA detection system from HRV (ADS-VHR1). To detect HRV behavior from time, frequency and non-linear measurements domains, throughout 60 minutes of classes in class room. To verify if the SA can be modulated by individuals Personality characteristics, Emotion and Chronotype in University students. Method: 12 systems ADS-VHR1 were validated using long segments with heart pulse recordings in a time no longer than 10 minutes, paired to a standard system, in a simple random sample, with three male volunteers. Subsequently, the Cardiac Pulses were recorded in a time of 60 minutes during 4 sessions of classes in a sample of 30 Nursing and Physiotherapy undergraduate students, with an average age of 25 ± 6,951. Subsequently, using a nonparametric procedure, it was verified how students psychological structure modulates the SA in classroom. Results: In the exploratory analysis for the validation of the, a Cross-Correlation Coefficient of r=0.569 to r=0.996; an Intraclass Cross-correlation of CCI=0.605 to CCI=0.998 and a Cronbach's Alpha of α=0.61 to α=0.99. The correspondence between the paired systems is confirmed by an analysis of variance. On the other hand, there were significant differences in HRV in the time series in the 60-minute window, in all its parameters (Time domain, Frequency and non-linear measurements), with a systematic reduction of heart rate to from the first 15 minutes until the end of classes. At the same time, there was no significant intra-group difference in any psychological measure associated with HRV. However, for Chronotype, in the 40th minute there is a difference with respect to the High Frequency band [χ²=9,853(3), p=0,020] and there is a significant difference between the Vespertino and Matutino groups [H=-20,1 (DV=-2.73), p=0.038]. Conclusions: The validity and reliability of ADS-VHR1 is demonstrated for what it was designed. It is concluded that the time of attention sustained in the university students has an important physiological activation in the first 15 minutes of a class. It was also verified that the Chronotype modulates, although in a diffuse way, the Sustained Attention in the university students in the classroom. It is recommended to continue with the studies.

9
  • JAQUEIUTO DA SILVA JORGE
  • Behavioral ecology of Mabuya agmosticha (Mabuyidae) in Encholirium spectabile (bromeliaceae): relevance of this association and of this host bromeliad to brazilian semiarid

  • Líder : ELIZA MARIA XAVIER FREIRE
  • MIEMBROS DE LA BANCA :
  • ELIZA MARIA XAVIER FREIRE
  • ADRIANO CALIMAN FERREIRA DA SILVA
  • RAUL FERNANDES DANTAS DE SALES
  • DANIEL CUNHA PASSOS
  • LEONARDO BARROS RIBEIRO
  • Data: 13-sep-2019


  • Resumen Espectáculo
  • The success of a species in a particular habitat or ecosystem depends on a range of behaviors, each with a specific purpose, always taking into account maximizing energy gain and decreasing costs. The habitat where the species lives guides its behaviors, most of them focused on the way of life in these places. Bromeliads, for example, are important habitats for many species, including reptiles, among which Mabuya agmosticha, a species of lizard of the Mabuyidae family, bromelicolous habitat and endemic from northeastern Brazil. Considering its close relationship with the Encholirium spectabile, a rupicolous bromeliad in the Brazilian semiarid, this study addressed the behavioral ecology of M. agmosticha in association with E. spectabile in the Agreste region of the state of Rio Grande do Norte, besides analyzing the importance of these host plants for biodiversity and the socioeconomics of the northeastern semiarid. Methodology: The fieldwork was carried out during monthly excursions, for four consecutive days, over a year, when the behaviors of this species of lizard in association with the bromeliads were observed and recorded, such as period of activity, diet, foraging behavior, thermoregulatory behavior and detection and flight of predators. This part of this field study was observational; To analyze the diet, data were collected during part of the Master's research. For foraging behaviors, the activities of each individual were categorized into Proportion of Time Spent Moving (PTM), Number of Movements Per Minute (MPM), Number of Successful Attacks on Prey per Minute, and Time on Watch. The influence of seasonality on diet and foraging behaviors was also tested. Circular statistics were used to evaluate the relationship between lizard position and the angle of incidence of sun rays and hours. The period of activity was tested by the number of active individuals over hours and days, as well as the effects of seasonality and interspecific variations in the population. Escape behaviors were expressed by the Flight Intiation Distance (FID) index, and the predator potential simulation was performed by a human observer. Other predator models, such as snakes, ontogeny on FID values, as well as the effects of seasonality, substrate temperature, caudal autotomy and between the sexes were also tested. To evaluate the importance of E. spectabile for the semiarid biodiversity and its socioeconomic role, fieldwork was carried out over nine years, allied to extensive bibliographic research. Results: The diet was basically composed of small arthropods; little consumption of plant material and no vertebrate prey. Termites make up 23.63% of the diet, followed by arachnids (14.93%) and cockroaches (7.52%), without significant seasonal differences. There were also no differences in the diet of males and females. Mabuya agmosticha presented PTM 18.3 ± 2.8% and MPM  3.8 ± 0.38 seconds per minute and passed on average 81.7% without moving; He captured approximately 1.72 ± 1.4 per minute stuck and passed on average 22.2 ± 7.62% of waking time. Significant differences in movement were found between males and females, and females and juveniles. Mabuya agmosticha showed significantly positive relationships with both the sun's angle of incidence and the hours of the day. This species remained active throughout the day, although it showed a preference for the start and end times of the day. It had an average FID of 3.1 ± 0.7 meters. Females had a higher FID than males and juveniles. Significant effect of substrate temperature on total FID was found, but not in relation to sex. Conclusions: The dependence of Mabuya agmosticha on macambira bromeliads distinguishes it from other sympatric species of the genus, and its food ecology is directly related to the use of bromeliads. Their dependence on these rupicolous bromeliads is a major threat to their survival in the face of overexploitation and possible disappearance of these bromeliads; Social and environmental policies aimed at the conservation of both species are essential. Regarding the importance of macambira bromeliads for the semiarid biodiversity and socioeconomic interest, these showed significant relevance, because they host a great diversity of associated species and numerous ecological and social interactions. Consequently, we propose the rupicolous bromeliad E. spectabile as a keystonespecies for the semiarid region, and we suggest more effective environmental policies for the conservation of these plants, which contribute so much to this region of Brazil.

10
  • RAYANE BARTIRA SILVA DO NASCIMENTO MENDONCA
  • RETINAL AFERENCE, CYTOARCHITETONIC CHARACTERIZATION AND MORPHOLOGY OF PULVINAR COMPLEX (Callithrix jacchus): A COMPARATIVE ANALYSIS BETWEEN ADULTS AND ELDERLY.

  • Líder : JEFERSON DE SOUZA CAVALCANTE
  • MIEMBROS DE LA BANCA :
  • FRANCISCO GILBERTO OLIVEIRA
  • JEFERSON DE SOUZA CAVALCANTE
  • JOSÉ RODOLFO LOPES DE PAIVA CAVALCANTI
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • SEBASTIAO PACHECO DUQUE NETO
  • Data: 30-sep-2019


  • Resumen Espectáculo
  • The pulvinar complex plays a key role in the processing and transmission of information between cortical areas. This nucleus receives inputs from various areas of major sensory systems, such as the cortex, and projects to areas of association of the cerebral cortex, and is thus considered as an associative nucleus. This structure is not identifiable in rodents or other small mammals. However, in primates or pulvinar complex it occupies much of the thalamus and is a component of the subcortical visual system as it receives afferences from the retina and superior colliculus and exhibits the necessary notifications for various areas of the neocortex. Classically this structure has four subdivisions, inferior, medial, lateral and anterior, neuronal density and fiber distribution, being the first three changes in visual processing. Aging is the biological process of decreased physiological function that involves neurological changes associated with cognitive decline, as well as neurodegenerative diseases during advancing age. The marmoset (Callithrix jacchus) is one of the New World primates of daytime habit and visual guidance, which is used in biomedical research because of its phylogenetic proximity to humans. Our objective was to perform a cytoarchitectonic characterization of the pulvinar complex in this species by performing a comparative analysis between two groups: adult and elderly animals, showing their subdivisions and identifying a distribution of neurons, axonal terminals and glial cells and subdivisions of this complex. For this purpose, histochemical and immunohistochemical techniques were used, as well as intraocular injection of neuronal tracker to display as subdivisions, neuronal distribution, glial cells, and currently complex fibers/terminals. All experiments were approved by the Animal Use Ethics Committee of UFRN (CEUA-UFRN Nº. 009.013/2017). Our results demonstrate the presence of subdivisions in the pulvinar complex in the anterior pulvinar nucleus (APul), medial pulvinar nucleus (MPul), lateral pulvinar nucleus (LPul) and inferior pulvinar nucleus (IPul) presenting the latter four subnuclei: inferior pulvinar centromedial (IpulCM), inferior medial pulvinar (IPulM) and posterior inferior pulvinar (IPulP). The pulvinar complex presents along its rostrocaudal extension, immunoreactive neurons to the specific neuronal nuclear protein (NeuN), the calcium binding protein calbindin (CB), besides glial cells immunoreactive to the glial fibrillar acidic protein (GFAP). Data in elderly animals differ from adult animals, as older animals have a lower intensity of cell labeling in NeuN and CB and a lower intensity of labeling in GFAP. The presence of immunoreactive fibers/terminals in the subunit b of the cholera toxin (CTb) was well evidenced in the IPul only in the medial subnucleus, contralateral to the injected eye, characterizing the presence of direct retinal projection in this nucleus. In older animals, a retinal projection shows discrete when compared to young animals. Despite being a qualitative study, our data indicate differences between adult and elderly animals, suggesting that the pulvinar complex may suffer a significant loss of functional character during the processing of visual information.

11
  • ISABELLA MARIA DE OLIVEIRA PONTES FERNANDES
  • Sex differences in behavior of rats submitted to chronic mild stress.
  • Líder : ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • MIEMBROS DE LA BANCA :
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • VICTOR ANASTÁCIO DUARTE HOLANDA
  • VANESSA DE PAULA SOARES RACHETTI
  • EZEQUIEL BATISTA DO NASCIMENTO
  • RAMÓN HYPOLITO LIMA
  • Data: 12-nov-2019


  • Resumen Espectáculo
  • Stress is characterized by physical and psychological changes triggered by external and internal pressures. Repeated exposure to stressful events promotes changes in an individual's cognitive, emotional, and behavioral processes, and such changes may be related to mental illness such as depression. Studies point to different stress coping strategies and data from the World Health Organization show that the incidence of depression and the response to antidepressant treatment are different between men and women and that this difference is related to the hormonal cycling that occurs in females. In addition, stress-induced cognitive changes and response to treatment in males and females are distinct, especially memories with emotional context, which are known to be directly influenced by sex hormones, and are still related to the mechanism of action of antidepressants used in the clinical practice, such as fluoxetine (FLX). However, most studies are conducted on males with the excuse that hormonal variation makes female analysis even more complex. Understanding the sexual differences in stress response in males and females is essential to prevent and treat pathologies that may arise from stress more effectively, looking up to the particularities of each individual. In this sense, we submitted male and female Wistar rats to the model of chronic mild stress (CMS), widely used to induce depressive-like behavior in animals, to investigate possible behavioral changes related to depression and fear memory, and its response to FLX treatment. At first, two pilot experiment were held to establish the time required to animals present depressive-like behavior and the moment of treatment beginning. The animals were submitted to 35 days of CMS and treated in the last 14 days with FLX or its vehicle (VEH), and were submitted to forced swimming (FST), open field (OF) and splash test (ST) before and after the FLX treatment, and contextual fear conditioning (CFC) at the end of the protocol. Females were separated by estrous cycle phases with high (proestrus and estrus - P/E) and low (metaestrus and diestrus - M/D) hormonal levels. Our data demonstrate that before treatment (TTT) only male-CMS showed depressive-like behavior represented by increased immobility time in FST compared to male-control (CTR), but not after TTT possibly because immobility memory retention impairment. After TTT femalesCMS showed increased climbing time, independent of FLX, and P/E-CTR showed reduced immobility time and increased active time compared to M/D-CTR, suggesting that estrogen may have an antidepressant effect. Also, CMS-FLX showed reduced immobility and increased active time compared to M/D-CTR-FLX but not P/E-CTR-FLX and CMS-VEH. In ST, male-CMS showed increased grooming time compared to male-CTR before TTT and male-CMS-VEH showed increased grooming time compared to male-CTR-VEH and after TTT. After TTT female-CTR-FLX showed reduced grooming time compared to female-CMS-FLX, showing conflicting results to literature. The animals of both sexes showed no differences in locomotor activity in OF, demonstrating that the effects observed in the other tests were not due to locomotion impairment. P/E-CMS explored less the center of the field than its CTR, suggesting an anxiogenic effect, possibly mediated by estrogen. In CFC male-CMS showed reduction in freezing time compared to CTR, regardless of treatment with FLX, suggesting impairment in fear memory caused by CMS only in male. In conclusion, our data show sex differences of CMS in response to FST and CFC. Male rats demonstrated to be more vulnerable to CMS exhibiting depressive-like behavior earlier than females and also fear memory impairment. On the other hand, female express depressive-like behaviors in phases of estrous cycle with low hormone levels (M/D) and high levels of hormones (increased estrogen) may have protective effect in females in depressive like behavior after chronic stress but no impact on fear memory.

2018
Disertaciones
1
  • LUANA PINI CAVALCANTI DE SOUSA
  • Rate of song change within a humpback whale (Megaptera novaeangliae) breeding stock

  • Líder : RENATA SANTORO DE SOUSA LIMA
  • MIEMBROS DE LA BANCA :
  • RENATA SANTORO DE SOUSA LIMA
  • MAURO PICHORIM
  • MARIA ISABEL CARVALHO GONÇALVES
  • Data: 16-mar-2018


  • Resumen Espectáculo
  • Humpback whales (Megaptera novaeangliae) migrate annually from feeding to breeding grounds in tropical and subtropical areas during the winter and spring. One of these reproductive habitats is off Brazil, where the Abrolhos’ Bank (Bahia) is the principal area of the subspecies M. n. australis occurrence and concentration in the Occidental South Atlantic Ocean. Throughout the breeding season, males produce complex and long vocalizations: the song. It is comprised of repetitive patterns and it is structured hierarchically by units, phrases and themes. Even though the song’s function is not fully understood, it is associated with the species sexual selection. The hypothesis most accepted is that the song is a way to attract females and may act as inter- and intra-sexual displays. Each population in the world has its own song version that evolves along the years with varying rates of change and all males from the same population incorporate these changes. The modifications and the learning of all the males result in different or new songs, phenomenon previously described as cultural evolution. There are few qualitative studies about the song evolution of the humpback whale population that visits Brazil, but to the best of our knowledge no quantitative study in medium temporal scale has been done yet. The present study aims (1) to describe the song themes of males in Brazil from 2006 to 2017, (2) to characterize themes composition in phrase level and (3) to identify theme sequences alterations quantitatively by Levenshtein distance similarity index method from 2000 to 2017. Data were collected by passive acoustic monitoring during the breeding season in Brazil (July to November). Just static themes were considered to define the median song of each year and a song cycle was compounded by a sequence of themes without repetition of themes. The results enabled verifying song cultural evolution in small temporal scale when comparing consecutive years and medium temporal scale when assessing a longer time interval (2000 to 2017). Inter- and intra-individual variations were found in different hierarchical levels of the song: unit, phrases and themes, probably reflecting the dynamics of the species’ sexual selection process. Qualitative analyses characterized the structure of the song from Breeding Stock ‘A’ (Brazil). Additionally, quantitative analyses showed different rates of change in the song over the years, demonstrating no single pattern. These results show that song cultural evolution within the population that visits Brazil is not directed by a single force emphasizing that and further research is necessary to define what is driving this phenomenon.

2
  • JADDE EMMYLLE SILVA DE MOURA
  • Are Roses Red and Violets Blue? The Influence of Emotions on Color Perception

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • MARIO ANDRE LEOCADIO MIGUEL
  • NELSON TORRO ALVES
  • Data: 17-abr-2018


  • Resumen Espectáculo
  • Colors are not just an aesthetic stimulus, they also directly affect human cognition and behavior. Studies called psychodynamics and color psychology, for example, indicate that the colors of an object, or a place, can induce emotions. Emotions, in turn, also interfere with color vision and perception, due to the ability of certain emotional states to induce changes in important neurotransmitters, directly affecting the excitation, which in turn causes contractions or dilations in the pupil, altering the amount of light that reaches the retina. Negative emotions such as sadness, for example, would impair the visual perception of color by triggering reactions that promote falls in dopamine levels, and disrupt pupil contraction, consequently impairing sensitivity to chromatic contrast. Already positive emotional states, such as joy, could be responsible for expanding visual attention. The present research observed the occurrence of the influence of the emotional states of joy or sadness on the perception of colors of the human vision. We investigate how that influence affects individuals with normal color vision and colorblind individuals, who in turn can no longer distinguish certain colors, the research will include the participation of 74 men between the ages of 18 and 35, colorblind and non-colorblind. All participants were submitted to the Beck Depression Inventory (BDI), the Ishihara Test, and the Lanthonny D-40 Hue color perception test and will watch a video of approximately 3 minutes of emotional stimulation. After the videos were taken, the participants again performed the color perception test and it was evaluated whether there was a significant change in the performance of the ability of their color perception. The data resulting from this work suggest that there is significant influence of emotion on both color perception and pupil size. Thus, as hypothesized initially, not only semantic information, but also emotional aspects seem to be involved in visual cognition and consequently in color perception of human vision.

3
  • SABRINA RUIZ BRONZATTO
  • THE EFFECT OF A BRIEF INTERVENTION OF LOVING-KINDNESS MEDITATION ON PROSOCIAL DECISION-MAKING
  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • LUIZ CARLOS SERRAMO LOPEZ
  • MARIA EMILIA YAMAMOTO
  • Data: 19-abr-2018


  • Resumen Espectáculo
  • Emotions and social skills such as perspective-taking, empathy, and compassion are fundamental to a highly social, like the human specie. It is considered that prosocial behavior emerged and remained evolutionarily because it presented a survival and reproductive differential for the species. It is suggested that there are stable individual characteristics that favor individuals to be more or less responsive in behaviors that help their co-specific ones, especially the personality trait called agreeableness and one of the affective components of empathy, empathic concern. It has been shown that exercises or mental training can influence the behavioral response to prosociality, and in particular are meditative techniques such as loving-kindness meditation (LKM). There are indications that even short LKM exercises may influence social decision-making by impacting on cognitive control and regulating emotional states, directing behavior towards greater prosociality. The main objective of the present study was to investigate the influence of individual differences, through agreeableness and empathy traits, and the effect of a brief LKM intervention on the prosocial decision-making of unilateral donation of resources and the help intention in different scenarios (travel and disease) as well as the coherence between them. We also investigated the effect of meditative intervention on the participants' emotional state. The sample consisted of 134 undergraduate students, divided into three experimental conditions: LKM, neutral control and positive control. There was correlation between the agreeableness trait and the help intentions in the travel and disease scenarios and a correlation between the empathy trait and the help intention only in the disease scenario. There was no correlation between socialization and empathy scores nor its subcomponents in relation to the task of donating resources to third parties. There was no difference among the experimental groups regarding the donation of resources to third parties nor regarding the help intentions. There was a positive correlation among the three prosocial tasks investigated only in the LKM group. The three experimental groups showed a decrease in negative affects after intervention and there was a reduction of positive affects in the neutral control group. The results suggest that the meditative interventions impact differently on the prosocial decision-making, and the brief intervention of LKM promoted greater coherence in the prosocial decision-making, between the help intention and the effective behavior of donation of resources to third parties. It is considered that the translated and adapted LKM protocol can open the way for future investigations with the use of easy-to-execute and low-cost techniques in Brazil. In addition, it is suggested that it has a potential applicability as a supporting measure for the improvement of subjective well-being through the regulation of emotional states, especially with regard to the reduction of negative affects, and the cognitive and affective controls on the decision-making process in social interactions, potentially reducing conflicts between intention and action.

4
  • NATÁLIA DE ARAÚJO MIRANDA TASSO
  • Blood Donation: Sociodemographic Aspects and Evolutionary Analysis

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • CARLOS ROBERTO SORENSEN DUTRA DA FONSECA
  • FIVIA DE ARAUJO LOPES
  • RONALDO PILATI RODRIGUES
  • Data: 24-abr-2018


  • Resumen Espectáculo
  • Donating blood is a pro-social behavior. By donating, we are able to save a person's life. In Brazil, the donor population rate still does not reach the minimum proportion stipulated by WHO, which is 1.76% in the country, when would be ideal to have between 3 and 5% of the donor population. Therefore, papers that investigates the motivational components for donation are important and urgent, in order to increase these numbers. In the first study, we did a systematic review in the literature of the last ten years, searching for Brazilian studies that approached blood donation from the motivational point of view. At the end of the selection criteria, 38 publications were analyzed. We believe that this number needs to increase, mainly because only one article was found in the psychology area. This area studies human behavior and therefore should be more present, since blood donation is a helping behavior that we find in our society. In study two, we surveyed the sociodemographic and socioeconomic profile of the donors. Our sample consisted of mostly of the donors being male, age between 18 and 27, Catholics/Protestants, complete high school and O blood type. In addition, more than 40% of the sample was in the highest socioeconomic levels (A and B1). This study showed that the socioeconomic factor can be an important component in the decision to become a donor or not. Finally, in study 3, we analyze some motivations related to donation. We found that the "It seemed right" motivation was more important for replacement donors and for men, "Moral/social obligation" and "Free snack" was more important to first-time donors and "I feel psychologically well make the donation "was more relevant to women. In addition, we saw that most of the first donations were spontaneous. In summary, this work showed that blood donation is a complex process, composed of several nuances and that it is necessary to bring knowledge from several areas of knowledge to understand the behavior more completely.

5
  • ELENICE SOARES
  • Evaluation of Maternal Prosociality as a Model for Children Prosociality.

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • ANUSKA IRENE DE ALENCAR
  • FIVIA DE ARAUJO LOPES
  • RONALDO PILATI RODRIGUES
  • Data: 26-abr-2018


  • Resumen Espectáculo
  • Evolutionary Psychology (EP) is a perspective that starts from the knowledge about the Theory of Evolution and uses them to seek to understand the behaviors and the human mind. It’s originated from the union of elements of cognitive psychology and evolutionary biology, presenting the advantage of undoing the existing dichotomy between the biological and cultural aspects that are common to other perspectives within psychology. The fundamental tenet of EP is that the human brain is shaped to solve issues related to survival and reproduction. To understand this it is necessary to keep in mind that the brain has been shaped over time in the so-called Evolutionary Adaptive Environment, that is, the environment where our hunter-gatherer ancestors lived. This environment had characteristics different from those currently found; the search for food possibly demanded more energy expenditure, the groups were smaller and with more related individuals, which increased the probability of cooperation between the individuals and made it easier to identify who was not collaborating for the common good, called free riders. In this context, some mechanisms were developed to deal with the occurrence of free riders in the group, such as kinship selection, reciprocal altruism and indirect reciprocity. In addition to these mechanisms, studies that include the understanding of cooperation from ontogeny add important elements related to the development context of the individual. Such studies aim to identify the modulating factors and how they influence the prosocial behavior of children by making possible comparisons among several of these factors, such as: gender, age, individual characteristics, as well as parental and cultural influences. In order to investigate whether there was influence of the maternal prosocial behaviors and the perception of this prosociality in the prosocial behaviors presented by the children, the study was conducted in Natal / RN and had the participation of 71 dyads composed of children between seven and eleven years old and their mothers. The mothers answered a self-report questionnaire about their prosocial behavior (BPP) and the questionnaire for sociodemographic characterization of the participants. The children answered a questionnaire about their perception of the prosocial behaviors of their mothers and participated in a round of the dictator's game as a behavioral measure of prosociality. Some similarities and differences were observed between the children's perception in relation to that reported by their mothers. In three factors (out of a total of 7), the means of mothers and children did not differ significantly, indicating that in these factors, children may be easier to identify the behaviors performed by them. The model created to investigate which variables influenced the prosocial behavior of the children explained 30% of the variation of the data, with one of the factors of BPP (Reasoning Related to the Other) and age presenting main effect, which requires more in-depth studies to investigate other variables that influence this behavior. Finally, children who demonstrated more prosocial behavior took less time to decide on donation, indicating that prosocial behavior may require less rationalization and would be more intuitive than pro-self behavior.

6
  • DANIELLA BEZERRA DOS SANTOS
  •  The influence of Higher Education on Sexual Selection

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • FIVIA DE ARAUJO LOPES
  • ROSANA SUEMI TOKUMARU
  • Data: 27-abr-2018


  • Resumen Espectáculo
  • Throughout life, some periods prove to be more meaningful than others, promoting personal changes. Therefore, life experiences shape the way we see ourselves and the world. In this way, we can point College years as an important period in someone’s life. College represents an intellectually rich environment that stimulates personal growth, in this scenario the student is exposed to a great diversity of people and knowledge. Thus, Higher Education acts as a catalyzer for personal changes, through which undergraduates get the chance to widen and reevaluate their perceptions. New physical and social environments promote changes in the way people see themselves, influencing, for example, their self-esteem (known as a sociometer) and self-efficacy (belief on your own capacity). Considering the importance of self-evaluation on sexual selection (e.g. mate value) and the potential of transformation promoted by college experience, it’s interesting to observe the relation between these self-perceptions (self-esteem and self-efficacy) and the influence on undergraduates’ self-perceived mate value. The present work was conducted using an undergraduate Brazilian population, students participating in the study were freshmen and seniors. Our aim was to compare how undergraduates’ self-perception on self-esteem, self-efficacy (general and specific to higher education) and self-evaluation as romantic partner (SRP) was presented, considering the different time exposure to college experiences and demands. On the first study, our goal was to verify the relation between self-esteem and self-efficacy in undergraduate students, one group initiating their college studies and other finishing their studies. For the second study, considering our knowledge from the literature on how self-esteem acts influencing people’s SRP and having established the relation between self-esteem and self-efficacy in our first study, our aim was to observe the influence of undergraduates’ self-efficacy on their SRP, analyzing this influence for both freshmen and seniors. Results indicated positive correlation between self-esteem and self-efficacy for undergraduate students from both college periods and both sexes, no significant difference was found between periods. Further, we also found an association between general self-efficacy and SPR but there was no significance for college period.  For the analysis involving SPR and higher education self-efficacy it was found significant association, for sex as well as college period. Thereby, the present research brought a new approach to sexual selection studies, using self-efficacy in the context of romantic partner selection and offering evidence that one’s own perception of mate value seem to be affected by personal beliefs relating to competence.

7
  • AMANDA TOLEDO PEREIRA DE CARVALHO
  • The influence of environmental cues in life history strategies

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • MARIA EMILIA YAMAMOTO
  • ROSANA SUEMI TOKUMARU
  • Data: 30-abr-2018


  • Resumen Espectáculo
  • One of the most fund––amental principles of Life History Theory is that natural selection has shaped life forms to harvest energy from the environment and convert it into replicates of themselves. However, fitness maximization does not always imply producing large amounts of offspring: considering environmental factors such as mortality and unpredictability is crucial to understand trade-offs performed by organisms along their lifespan, therefore, their life history strategies, which are organized around a fast-slow dimension. Fast strategies are characterized for greater energetic allocation in tasks and traits related to current reproduction, while slow strategies are future-oriented, allocating energy towards somatic effort. Human beings lie on the slow end of the continuum, but still exhibit intraspecies and populational variation. In the past decades, the global phenomenon of fertility decline in spite of the current affluence of resources have been challenging tenets of human reproductive behavior. In this context, in our empiric study we sought to understand how factors such as mortality, unpredictability, socioeconomic context and populational density might explain variation in reproductive strategies in a Brazilian sample. We found evidences that mortality, childhood unpredictability and socioeconomic context predict some life history behavioral markers such as reproductive effort, idealized offspring quantity, idealized age of first reproduction and length of commited relationship. Our results partially corroborate current literature about the interaction between environment and life history strategies development. On the other hand, we found unusual results regarding the relation between childhood context and life history strategies, which demonstrate that more investigation on this subject is required, especially in countries out of North American and European contexts, such as Brazil.

8
  • RAFAEL VITOR LIMA DA CRUZ
  • A Single Dose of 5-MeO-DMT Stimulates Adult Neurogenesis in Mouse Dentate Gyrus

  • Líder : RICHARDSON NAVES LEAO
  • MIEMBROS DE LA BANCA :
  • RICHARDSON NAVES LEAO
  • EDUARDO BOUTH SEQUERRA
  • WILFREDO BLANCO FIGUEROLA
  • Data: 24-may-2018


  • Resumen Espectáculo
  • The subgranular zone (SGZ) of dentate gyrus (DG) is one of the few regions in which neurogenesis is maintained throughout adulthood. It is believed that newborn neurons in this region encode temporal information about partially overlapping contextual memories. The 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a naturally occurring compound capable of inducing powerful psychedelic states. Recently, it has been suggested that N,N-Dimethyltryptamine (DMT) analogues can be used in the treatment of mood disorders. Due to the strong link between altered neurogenesis and mood disorders, we tested whether 5-MeO-DMT is capable of increasing DG neurogenesis in vivo. We show that a single intracerebroventricular injection of 5-MeO-DMT increases cell proliferation in the DG, as evinced by 5-Bromo-2′-deoxyuridine (BrdU) staining. Moreover, using a transgenic mouse that expresses tamoxifen-dependent Cre recombinase under doublecortin (DCX) promoter control, we found that newborn DG granule cells have more complex dendritic morphology after 5-MeO-DMT. Moreover, newborn granule cells display longer afterhyperpolarization potentials (AHP) and lower action potential threshold when compared to 5-MeO-DMT treated. Our findings show that 5-MeO-DMT affects neurogenesis and this effect may contribute to the known antidepressant properties of DMT-derived compounds.

9
  • PABLO FELIPE GONÇALVES DE ARAÚJO SANTOS
  • HIERARCHY INFLUENCE IN THE SOCIAL INTERACTION DYNAMICS OF Callithrix jacchus MALES IN NATURAL ENVIRONMENT.

  • Líder : ARRILTON ARAUJO DE SOUZA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • MARIA EMILIA YAMAMOTO
  • WALLISEN TADASHI HATTORI
  • Data: 29-ago-2018


  • Resumen Espectáculo
  • Cooperation is an affiliative social interaction that brings a gain to all involved. In a social group, investment in this interaction provides a cooperative response as a direct result. In primates, affiliative social interactions reinforce the bonds between individuals in the group. There are also agonistic interactions, which refer to behaviors used in aggressive and submissive contexts, but these are less frequent in primates. Callithrix jacchus males play an important role in the relationship cooperation x competition in this species. In order to understand the interactions dynamics of more complex societies, many researchers use networks approach to find a refined design of social groups structural aspects. In this study, male subjects (adults and subadult) of a marmosets group were observed twice a month, as well their affiliative and agonistic behaviors were recorded. Affiliative behaviors (grooming and contact) were documented by the focal animal method, recording the duration and frequency of interactions, while agonistic behaviors (avoidance, escape, submission, intimidation and fight) and sexual behavior (mount) were documented by behavioral sampling. The collected data were used in the social network elaboration and other analyzes. The results showed that grooming and contact duration, and the aggressions frequency did not differ statistically. However, the affiliative behaviors frequency, grooming and contact, differs between males, with the dominant showing such behaviors more frequently. Sociograms show that affiliative dynamics and agonistic interactions between males differ. We have verified that the breeder and the second male in the hierarchy succession perform more agonistic displays for other individuals. The breeder also holds the largest number of affiliative interactions while the others are similar in these interactions. We found that there is a social interaction asymmetry involving C. jacchus males in the Caatinga environment, and this asymmetry is related to the dominance position occupied by the animal in the social group.

10
  • ANGELICA KAYNNE DA CUNHA MOURA
  • Networks of support (online and offline), happiness and personality: Differences between generations

  • Líder : MARIA EMILIA YAMAMOTO
  • MIEMBROS DE LA BANCA :
  • ALEXSANDRO LUIZ DE ANDRADE
  • FIVIA DE ARAUJO LOPES
  • MARIA EMILIA YAMAMOTO
  • Data: 30-ago-2018


  • Resumen Espectáculo
  • Group life is a determining factor for the life of various animal species, especially Homo sapiens, which is a social animal par excellence. In recent years we have had a new way of socializing with the arrival of online networks. In this context, we aim to investigate whether individual factors such as age, personality and happiness influence the organization of online and offline support networks. We conducted the research in public institutions of the capital (Natal / Rio Grande do Norte-RN) and in the interior (Pendências / RN), with 297 participants, between 12 and 68 years old, who were grouped in adolescents, adults and adults. Through questionnaires (socioeconomic, Reduced Markers for Personality Assessment, Subjective Happiness Scale and a Social Networks Questionnaire), we showed the size and frequency of contact of the off-line support network, being greater in relation to the support network online for the three age groups. Among the age groups, the size of the online support network has a strong relationship with the offline network. Thus, in general, people who are part of the online network are also part of the offline network, although each age group has its particularities, which will be pointed out in the present work. Regarding subjective happiness, it is not influenced by the place where the person lives (interior or capital); is influenced by offline emotional proximity, although the effect disappears when age groups are separated; correlates negatively with the frequency of on- and off-line contact in emergent adults; and is influenced by the size of offline networks in the three age groups, but the size of the online network only influences the happiness of adolescents and emerging adults. Regarding personality characteristics, more neurotic adolescents present larger online sizes and those who score more in conscientiousness present a greater emotional proximity offline; more open emergent adults feel less emotionally close in such relationships; and more extroverted adults exhibit greater emotional closeness offline. In general, we find behavioral differences between the generations, which we understand to be explained by cultural evolution.

11
  • CARLA JÉSSICA RODRIGUES SALES
  • Endocrine and behavioral profile of common marmoset (Callithrix jacchus) at young age in the family group and during social isolation

  • Líder : MARIA BERNARDETE CORDEIRO DE SOUSA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • MARIA DE FATIMA PEDROSA PINTO BARBOSA
  • Data: 31-ago-2018


  • Resumen Espectáculo
  • Common marmoset, Callithrix jacchus, is a New World primate considered an important experimental model. Until very recently, most of the studies have been performed using adult marmosets in different areas of interest, such as genetics, metabolism and, mainly, neurosciences. The study of the stress response in this model has also produced relevant information, where mature males and females present a behavioral and endocrine dimorphic response. In the perspective of current models for depression and considering the high prevalence of 18% of this neuropsychiatric disorder in the human population, and around 14% in adolescents, the use of these animals during development is in the initial phase of research. Therefore, studies with immature animals are necessary to validate this experimental model in the early stages of its development. The objective of this study was to describe the hormonal and behavioral changes in immature males and females within family group and during social isolation. Twenty-nine animals with ages of 6 (n = 8, 4 males), 9 (n = 10, 5 males) and 12 (n = 11; 5 males) were used, where data collection occurred in the family group (baseline), in the first 2 days (FEI) and in the last two days (FEF) after separation for 3 weeks, and two days after the animal returned to the family group (reunion). Females presented significant changes in cortisol at 3 studied ages and males responded by increasing cortisol faster than females at 9 months, while cortisol elevation at this age in females occurred at the final stage of the separation period. The behavior of the females showed significant differences in the autogrooming in relation to that of males and the behavior of scent marking showed an increasing profile with the age of both males and females. The food intake behavior, modulated by the hypothalamic-pituitary-adrenal (HPA) axis, showed a decrease in the final phase of the study in females and needs to be investigated in males. These results indicate the potential of common marmosets, at young age, as an important experimental model, when exposed to isolation, for the study of psychiatric disorders in adolescence, and emphasizes that the protocols should be aware to the sex and age of the animals in their use as experimental models.

12
  • NATHÁLIA KAREN MAIA BEZERRA
  • Psychophysiological modulation of stress on in vitro fertilization treatment.

  • Líder : NICOLE LEITE GALVAO COELHO
  • MIEMBROS DE LA BANCA :
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • NICOLE LEITE GALVAO COELHO
  • RUI ALBERTO FERRIANI
  • Data: 31-ago-2018


  • Resumen Espectáculo
  • The infertility is reaching an increase number of women of reproductive age. The probability of conception per female reproductive cycle, which is naturally low, approximately one fifth, is further reduced when psychosocial and physiological stressors are associated. In this context, the use of modern assisted reproductive technologies has been enable achieving pregnancy but these procedures require extensive and invasive therapeutic protocols and usually involve expensive investment, thus causing high expectations, anxiety and stress. Increase the success rate of assisted reproduction treatments is the greatest challenge in the area today. It is believed that psychophysiological factors associated with the stress response system, such as cortisol, modulate directly or indirectly the success of treatment. The present study showed that patients who were pregnant at the end of the in vitro fertilization treatment (IVF) (n = 7), which was realized at Center for Reproductive Assisted Reproduction of the Januário Cicco Maternity School of Federal University of Rio Grande do Norte (UFRN), presented a less anxious profile and lower salivary cortisol awakening response than patients unsuccessful in the treatment (n = 13). These patients, in turn, presented lower perception of social support and modes of coping with problems centered on religious practices and / or fanciful thoughts. Understanding how these factors correlate with the success of IVF treatment can and should facilitate the practice of effective interventions in assisted reproductive services in order to reduce stress and provide an emotional adjustment to patients, which should therefore contribute for better pregnancy rates.

13
  • LARISSA DA MATA OLIVEIRA PRADO
  • BACKGROUND COLOR AND BRIGHTNESS PREFERENCE BY THE SOUTH AMERICAN ELECTRIC FISH ITUÍ-CAVALO (Apteronotus albifrons

  • Líder : DANIEL MARQUES DE ALMEIDA PESSOA
  • MIEMBROS DE LA BANCA :
  • ANDRE CARREIRA BRUINJÉ
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • Data: 27-sep-2018


  • Resumen Espectáculo
  • The Gymnotiform weakly electric fishes are widely used as animal models for studies in electrocommunication. The theoretical body regarding the vision of these animals is scarce, since their eyes are less developed than their electric sense. In comparison to the physiological evidence from the Gymnotiform Eigenmannia virescens, it is believed that the South American electric fish Ituí-cavalo (Apteronotus albifrons) is a long-wave-sensitive cone monochromat. However, no experiment demonstrated the color perception in this animal by behavioral basis, nor was the influence of the brightness cue on its natural behavior investigated. In the present study, eight Ituí-cavalos in the UFRN Sensory Ecology laboratory were tested for preference of brightness and color by comparisons on backgrounds. The stimuli were designed after visual modeling for the photopic and mesopic vision of the fish under 800 and 8 lux, respectively. The brightness parameters were referenced at 40, 65, 70 and 100% to the gray color reflectance standard, while the chromaticity parameters were 100% of the reflectance pattern of the yellow and green colors. Circular backgrounds were divided into three equal parts, one for the brightness experiment, divided into gray40 (dark), gray65 (intermediate) and gray100 (light), and one for color test, divided into yellow100, green100 and gray70. The greys used in the brightness test were controlled for the same chromatic value and varied only in achromatic value, inciting discernment based solely on the brightness cue; in the color test, all colors were controlled for the same achromatic value and only varied in chromatic value, guaranteeing that the animal would only differentiate them if it had color vision. The time spent/area of the stimulus was recorded as a deterministic parameter of preference. The results showed that the Ituí-cavalo had a population preference for darker shades, avoiding the lightest one, and that the possible color preferences were individual and without any discernible pattern. The preference for dark backgrounds can be justified as a possible maneuver to reduce stress and/or risk of predation, as observed in Heterandria formosa, while color preference rests on a possible visual modeling mismatch, since the spectral sensitivity of a close species was considered in the absence of accurate physiological evidence on Ituí-cavalo. These findings demonstrate the importance of behavioral experimentation for the practical verification of physiological studies. 

Tesis
1
  • RAUL FERNANDES DANTAS DE SALES
  • Behavioral ecology of the lizard Ameivula ocellifera (Squamata: Teiidae) in different phytophysiognomies of northeastern Brazil 

  • Líder : ELIZA MARIA XAVIER FREIRE
  • MIEMBROS DE LA BANCA :
  • ELIZA MARIA XAVIER FREIRE
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • LEONARDO BARROS RIBEIRO
  • VANDERLAINE AMARAL DE MENEZES
  • Data: 30-abr-2018


  • Resumen Espectáculo
  • Lizards of the family Teiidae are recognized as active foragers that maintain elevated body temperatures in activity, and do not defend territories, so that both males and females have opportunities to mate with several partners during the breeding season. However, there are few available studies that quantitatively analyzed the behavior of teiids, especially in South America. In this perspective, the purpose of this study was to investigate the foraging, thermoregulation and reproduction behaviors of the whiptail lizard Ameivula ocellifera, a conspicuous species widely distributed in the Northeastern region of Brazil, aiming to contribute to the knowledge about the behavioral ecology of South American teiids. To collect behavioral data, field excursions in two seasons of the year (dry and rainy seasons) were carried out in three locations in the state of Rio Grande do Norte, two in the Caatinga domain (Lagoa Nova and Acari), and one in the Atlantic Forest domain (Nísia Floresta). To complement the analysis of reproductive behavior, we also used behavioral data from two additional localities (Natal and Serra Negra do Norte). The focal observations were recorded with a digital camcorder, and the videos were later analyzed by the continuous animal focal method. Some animals were captured after video records for analysis of diet and body temperatures. The diets of Lagoa Nova and Acari populations were predominantly composed of termites and insect larvae, respectively, while the Nísia Floresta population presented a more generalized diet, without a single predominant prey category. The foraging behavior was characterized by high indices of movement and active search for prey, but the population of Nísia Floresta presented a lower rate of active search in relation to the two caatinga populations because lizards spent more time exhibiting vigilance. There were also differences in the main mode of prey discovery among the population of Nísia Floresta (visual and chemosensory search while moving) and caatinga populations (digging the substrate). In Lagoa Nova population, seasonal differences in foraging behavior were observed. Behavioral adjustments in response to changes in prey availability and differences in vigilance time against predators are plausible explanations for seasonal and population differences in foraging behavior. The active body temperatures (TC) varied between 32.4 and 43.4 °C, with similar mean values among the three populations, in the range of 38-39 °C. Despite the similarity in TC, lower values of substrate temperatures (TS) and air temperatures (TA) were recorded for Lagoa Nova. When comparing the three populations during the rainy season, it was verified that animals from Lagoa Nova spent more time in the sun and less time in the shade than the other two populations. In addition, TS and TA varied seasonally in Lagoa Nova, with lower values in the rainy season, and animals spent more time exposed to the sun and less time exposed to filtered sun in the rainy season than in the dry season. A positive relationship was observed in the three populations between the time exposed to cloudy conditions and basking time, and lizards from Acari spent more time basking in comparison to the other two populations. The results suggest that the maintenance of similar TC between populations and throughout the year in Lagoa Nova occurred due to flexibilities in thermoregulatory behavior that reduced the impact of changes in environmental conditions. The mating system of A. ocellifera is characterized by consensual copulations preceded by male courtship, and post-copulatory accompaniment of the female, with the male companion repelling rival males, and guarding the entrance to the female's burrow when she finishes daily activity. Additionally, some males may copulate opportunistically with a female without previous courtship. The accompaniment has survival costs for companion males, as they spent more time in vigilance, less time performing active search for prey, captured less prey, and initiated 75% more agonistic interactions against other males when compared to males foraging alone. Females can benefit from post-copulatory courtship and access to high-quality males. Opportunistic copulations, on the other hand, may be a conditional strategy adopted by less dominant males to achieve mating, but presumably confer a lower fitness value.

2
  • EZEQUIEL BATISTA DO NASCIMENTO
  • Modulatory effects of sex steroids hormones in socially isolated female: a study about neuroendocrine profiles related to emotional and cognitive changes

  • Líder : ALESSANDRA MUSSI RIBEIRO
  • MIEMBROS DE LA BANCA :
  • ALESSANDRA MUSSI RIBEIRO
  • DEBORAH SUCHECKI
  • JOSE RONALDO DOS SANTOS
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 17-may-2018


  • Resumen Espectáculo
  • Stress can be defined as a set of physical and psychological mechanisms to coping disturbances that threat the homeostasis. Long-term exposure to stressful events is associated with negatives effect on cognition, emotion and behavior, moreover, these alterations are suggested to be in onset of psychiatric disorders. Glucocorticoids (GCs) are the main hormones involved in stress response. The glucocorticoids receptor (GR) are extensile expressed in different types of tissues in the body, including the central nervous system (CNS), especially in hippocampus, amygdala, and prefrontal cortex. These structures are involved in mood regulation, anxiety and mnemonic processes and are targets of the stress. Although, it remains controversial how stress can impair functionality in these brain areas and how it correlates with disturbances in mood, anxiety and memory impairment. In contrast, oscillations of sex hormones, such as estradiol and progesterone, can profoundly influence the CNS, acting against deleterious effects of stress. In this regard, we used an animal model of chronic stress - social isolation - in female rats with intact estrous cycle to investigate modulatory effect of sex steroid on cognitive and emotional responses. Moreover, we investigated the dissociative effect of estradiol and progesterone, using agonist or antagonist. Our main results demonstrated that: (1) females in diestrus showed depressive-like behaviors and memory deficits when compared to estrus and proestrus phases; (2) depressive-like behaviors and memory deficits induced by social isolation was estrous-cycle dependent; (3) stressed females treated with estradiol (but not progesterone) showed less depressive-like behaviors and memory impairments; (4) tamoxifen (but not mifepristone) induced depressive-like behaviors in proestrus females; (5) There was a anxiolytic effect induced by progesterone. Taken together, these findings suggest that endogenous variations of sex hormones are important to modulate mood, anxiety and mnemonic process in socially isolated females.

3
  • ALANE DE MEDEIROS SILVA
  • CYTOARQUITETONIC AND MORFOQUANTITATIVE CHARACTERIZATION  OF THE MIDLINE AND INTRALAMINAR THALAMIC NUCLEI AND ITS GLUTAMATERGIC NEURONAL POPULATION IN ROCK CAVIES (Kerodon rupestris)

  • Líder : EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • MIEMBROS DE LA BANCA :
  • CLARISSA LOUREIRO CAMPÊLO BEZERRA
  • EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • FERNANDO VAGNER LOBO LADD
  • FRANCISCO GILBERTO OLIVEIRA
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 27-ago-2018


  • Resumen Espectáculo
  • Glutamate (Glu) is a fundamental neurotransmitter in the processing of sensory functions, development and maintenance of cognitive processes. Among brain regions where it can be found, stands out the thalamus, a structure directly involved in both integration and modulation of sensory inputs from the periphery to the cerebral cortex. The midline/intralaminar nuclei (ML/IL) constitute a significant portion of the thalamus and have a global influence on cortical functioning. Herewith, we aim to characterize the morphology and stereology of the ML and IL nuclei of the rock cavy thalamus (Kerodon rupestris), a typical rodent of the Brazilian Northeast, as well as morphological aspects previously neglected so far on the glutamatergic neurons in LM/IL. We used 6 young adult rock cavies, whose brains were submitted to Nissl technique and immunohistochemistry against Glu. The reference volume (Vref) of ML and IL was obtained, which presented statistical difference between them, being IL bulkier than ML. The volume density (Vv) of neuronal bodies immunoreactive to Glu (IR-Glu) between ML/IL did not present statistical difference. However, in the IL nuclei, there was a higher Vv. The total volume of IR-Glu (VTot) neurons between ML/IL presented IL statistically larger than ML. The IR-Glu neuronal bodies visualized among the ML nuclei were characterized predominantly rounded and ovoid. In addition, mean cell area was statistically lower in the ML nuclei when compared to IL. As soon, similar nuclear organization in the ML/IL was revealed in the rock cavy compared to other species. On the other hand, both morphometric and stereological data have shown particular features concern to the glutamatergic neurons in the ML/IL thalamic nuclei in the rock cavy. In more general terms, differences in glutamatergic nuclear organization in the thalamus, may be related to diversity on how thalamic activity influences cortical function among species.

4
  • DIANA QUITÉRIA CABRAL FERREIRA
  • EVALUATION OF FOOD NEOPHOBIA, BODY IMAGE AND SELF-ESTEEM OF ADULTS UNDERGOING TO BARIATRIC SURGERY

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • MARIA EMILIA YAMAMOTO
  • SANCHA HELENA DE LIMA VALE
  • Valdiney Veloso Gouveia
  • WALLISEN TADASHI HATTORI
  • Data: 28-ago-2018


  • Resumen Espectáculo
  • Obesity, characterized by excessive accumulation of adipose tissue, is considered a serious public health problem and increasingly reaches the adult population. Bariatric surgery (BS) has proven to be an effective method for the treatment of obesity, but this procedure can cause significant changes in perception and body satisfaction, self-esteem and in the eating behavior. After surgery, some people often have difficulties in including unfamiliar foods in their diet, which may characterize food neophobia (FN), defined as reluctance to eat unfamiliar foods. In this sense, the aim of this study was to evaluate the explicit and implicit FN, body image and self-esteem of adults undergoing BS. This research is composed by 3 studies. In Study 1, a cross-sectional correlational study was carried out with 140 adults, both sexes, applying the Food Neophobia Scale (FNS) and the Implicit Association Test for food neophobia (IAT-FN). For studies 2 and 3, a prospective longitudinal cut study was performed with adults, both sexes, submitted to BS evaluated at 3 moments: preoperative, 3 and 6 months after the BS. In the second study 37 eutrophic and 68 obese individuals responded to FNS and performed IAT-FN. In the third study 35 obese answered the Rosenberg Self-Esteem Scale and the Brazilian silhouettes Figures Scale for Adults, the three time points. The results of Study 1 showed that IAT-FN represents a satisfactory tool for FN assessment, showing no association with the explicit FN measurement. In Study 2 it was found that the explicit and implicit response of FN in eutrophic group was like obese participants in the preoperative period. It was also observed that obese individuals presented greater neophobia 3 months after BC, but the implicit measure did not change. In Study 3 it was seen that after BS there was a significant improvement in perception and satisfaction with the body image, accompanied by an increase in the participants' self-esteem. These findings bring relevant contributions in the clinical practice of health professionals who accompany individuals submitted to BS, helping to better understand the effects of surgery under aspects related to neophobic food behavior, satisfaction with new body image and self-esteem.

5
  • ALINE LIMA DIERSCHNABEL
  • ACUTE STRESS IMPAIRS LONG-LASTING STORAGE OF AN AVERSIVE MEMORY

  • Líder : JEFERSON DE SOUZA CAVALCANTE
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA BIONE KUNICKI
  • JANINE INEZ ROSSATO
  • JEFERSON DE SOUZA CAVALCANTE
  • MARIANA FERREIRA PEREIRA DE ARAUJO
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 19-oct-2018


  • Resumen Espectáculo
  • Learning and memory are plasticity-related processes guided by our life experiences. Emotions reflect ability to assign valences to those events, making learning of aversive experiences more leaning to persist. Long-lasting storage of a memory is controlled by intracellular signaling cascades activation after learning, which can be modulated by external agents, as stress. Modulation of cognitive functions could be caused by changes at cellular and/or neural levels, through decrease in neurotransmitter release, deactivation of specific kinase pathways, protein synthesis and connectivity damage between limbic brain regions. The aim of our study was to investigate the effect of after training acute stress on the persistence of an aversive memory in rats submitted to avoidance discriminative in elevated plus maze, an apparatus that simultaneously evaluates learning, memory, anxiety and locomotor activity. Our results show that memory lasted up to five days in this task, accompanied by an increase of Zif268 expression in the CA1 sub-region of dorsal hippocampus 18 hours after training. Stress immediately after training diminished long-lasting memory storage and decreased late protein synthesis of Zif268 18 hours after training and C-fos 1 hour after training. The exact mechanism underlying Zif268 and C-fos down-regulation still not clear. However, we suggest that glucocorticoids deregulate MAPK/ERK, JNK and p38MAPK signaling pathways in dorsal hippocampus pyramidal neurons, leading to dysfunctional expression of immediate-early genes.

6
  • FELIPE PORTO FIUZA
  • Aging of the rat lateral geniculate nucleus: morphological changes and daily rhythm of calretinin.

  • Líder : JEFERSON DE SOUZA CAVALCANTE
  • MIEMBROS DE LA BANCA :
  • FERNANDO VAGNER LOBO LADD
  • FRANCISCO GILBERTO OLIVEIRA
  • JEFERSON DE SOUZA CAVALCANTE
  • MANUELA SALES LIMA NASCIMENTO
  • RUTHNALDO RODRIGUES MELO DE LIMA
  • Data: 09-nov-2018


  • Resumen Espectáculo
  • Normal aging is accompanied by declines in visual system even in the absence of pathological processes. Among the components of this system, the lateral geniculate nucleus (LGN) comprises the dorsal lateral geniculate nucleus (dLGN), intergeniculate leaflet (IGL) and ventral lateral geniculate nucleus (vLGN). A characteristic of these nuclei is the immunoreactivity of calcium binding proteins (CaBPs), which regulates the intracellular concentration of this ion and presents a daily and regional expression. In parallel, modern theories of aging correlates functional deficits of neurons to dysregulation of calcium homeostatic mechanisms. In this context, the present study aims to describe quantitative morphological parameters of LGN and immunoreactivity of the CaBP calretinin (CR) in distinct phases of day across different age groups. Male wistar rats were divided into three age groups: young, middle-age and aged (3, 13 and 23 months old) and perfused with formalin (10%) in Zeitgeber times (ZTs) corresponding to distinct photic conditions, namely ZT 0 (dark/light transition), ZT 6 (light), ZT 12 (light/dark transition), ZT 14( beginning of dark) and ZT 18 (dark) . Then, the brains were sectioned and submitted to immunohistochemistry for Neuronal Nuclei protein (NeuN) with Nissl counterstain or immunohistochemistry for CR. Through the stereological methodologies of optical fractionator and Cavalieri estimator we estimated the regional volume, neuronal and glial number, glia/neuron ratio and CR+ neuronal number in the CGL nuclei. We observed LGN neuronal numbers remained stable during aging. However, glial numbers, glia/neuron ratio and volume increased in a region-specific manner. In addition, we observed a peak of CR-immunorreactive cells in the light phase that was diminished in the beginning of the dark in all LGN subnuclei of young animals. Furthermore, we show na age-related reduction of CR+ cells in all subnuclei at ZT 12, as well as in ZT 6 of IGL and the external portion of vLGN. These reductions seem to be due to the neuron capacity in express CR rather than neuronal loss, since no alterations were observed in total cell numbers. The daily rhythm of CR observed in young is lost in middle-aged and aged animals and were detected only in the light phase.

7
  • VICTOR ANASTÁCIO DUARTE HOLANDA
  • Role of the peptidergic system of nociceptin / orphanin CF in depressive behavior in mice

  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ELAINE CRISTINA GAVIOLI
  • HINDIAEL AERAF BELCHIOR
  • JANINE INEZ ROSSATO
  • MARIANA FERREIRA PEREIRA DE ARAUJO
  • SILVÂNIA MARIA MENDES VASCONCELOS PATROCÍNIO
  • Data: 23-nov-2018


  • Resumen Espectáculo
  • Introduction: Nociceptin/orphanin FQ (N/OFQ) is the endogenous ligand of a receptor coupled to Gi protein named NOP receptor. Both N/OFQ and NOP receptor are widely expressed in brain areas involved in the processing of emotions. Clinical and preclinical evidence suggests antidepressant effects due to the blockade of the NOP receptorThis study aimed to investigate the role of the N/OFQ-NOP receptor system in the modulation of depressive-like behaviors in mice. Methods: Male Swiss and CD1 mice and mice knockout for the NOP receptor (NOP (-/-)) were used in this study. The forced swimming test (FST) and the learned helplessness model (LH) were used to evaluate the depressive-like behavior of mice. Firstly, the effects of NOP agonists, antagonists and NOP(-/-) phenotype were investigated in the acquisition of the helpless behavior. The effects of co-administration of NOP agonists and classical antidepressant drugs on TNF and DA were also investigated. Results: The NOP agonists, Ro65-6570 (0.01-1 mg/kg, ip) and MCOPPB (0.1-10 mg/kg, ip), pre-induction sessions, increased the percentage of mice developing the helplessness behavior. In contrast, blocking the NOP receptor with the antagonist SB-612111 (1-10 mg/kg, ip) reduced the percentage of mice exhibiting helpless behavior, and similar results were observed in NOP(-/-) mice. Interesting enough, under the same experimental condition, administration of nortriptyline (20 mg/kg, ip) did not alter the acquisition of helpless behavior. In the second part of this study, fluoxetine, nortriptyline, R-ketamine and SB-612111 induced similar antidepressant-like effects in the TNF. Administration of the NOP agonists, N/OFQ and Ro 65-6570, did not induce any behavioral changes. However, co-administration of N/OFQ and Ro 65-6570 blocked the antidepressant effects of SB-612111, fluoxetine and nortriptyline, but not R-ketamine, in FST. Likewise, the systemic injection of SB-612111, nortriptyline, but not R-ketamine, reversed the helpless behavior of the mice exposed to LH. Co-administration of Ro 65-6570 blocked the antidepressant effects of SB-612111 and nortriptyline, but not R-ketamine. Conclusion: The activation of NOP receptor signaling facilitates, while its blockade, prevents the acquisition of helpless behavior. Furthermore, NOP receptor activation interferes with the antidepressant effects of monoaminergic drugs, including nortriptyline and fluoxetine, but not R-ketamine. Ultimately, these findings indicate a pro-depressive profile due to the activation of the NOP receptor signaling during a stressful event, as well as contribute to the investigation about the role played by the N/OFQ-NOP receptor in the regulation of mood states.

8
  • INGRID BRASILINO MONTENEGRO BENTO DE SOUZA
  • Experimental depression induced by acute and repeated administration of dexamethasone in mice: an appliance for studying the antidepressant potential of NOP antagonists

  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ELAINE CRISTINA GAVIOLI
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • VANESSA DE PAULA SOARES RACHETTI
  • FLAVIO FREITAS BARBOSA
  • IRIS UCELLA DE MEDEIROS
  • Data: 14-dic-2018


  • Resumen Espectáculo
  • Major depression can be triggered by stressful events which deregulate the hypothalamic-pituitary-adrenal axis response, promoting, in some circumstances, sustained elevation of circulating glucocorticoid levels. Hypersecretion of glucocorticoids may alter the functionality of glucocorticoid (rG) receptors at the CNS level, especially on the HPA axis and the hippocampus, generating behavioral abnormalities observed in patients with depression. Clinical and preclinical findings suggest antidepressant effects due to the blockade of the NOP receptor signaling. This study aimed to investigate the behavioral effects of acute and chronic administration of dexamethasone in mice and the NOP receptor antagonist, SB-612111, in this experimental model. Male and female Swiss mice were used. The behavior of the depressive type was evaluated through the Tail Suspension Test (TSC), the splash test and the social interaction test; in addition, the spontaneous locomotor activity of the mice was measured in the open field. Dexamethasone (64 μg / kg, sc) was capable of altering the behavior of the mice, inducing a depressive-like state in males and females, by increasing TSC immobility time, self-cleaning latency in the splash test, and reduce the frequency of interactions with an unknown animal. Treatment with the anti-depressants Nortiptilin (i.p) and Venlafaxine (i.p) reversed most of these behaviors, except for social interaction. Also, acutely administered dexamethasone did not affect the spontaneous lomocoção of the animals, however the acute administration of Nortiptilina and Venlafaxina significantly reduced the distance covered. In addition, the data point to similar behavioral change in males and females, thus characterizing this protocol as a good inducer of experimental depression. NOP receptor antagonist treatment reversed the depressive-like behavior caused by the acute administration of dexamethasone in the TSC and reduced the latency for self-cleaning in the splash test, without altering the locomotion of the mice. For the repeated protocol, dexamethasone (16 μg / kg, s.c.) was administered for 14 days and the behavior measured at two times (eighth and sixteenth day). In the first seven days, dexamethasone showed a depressive type profile responding with elevated immobility in the TSC and increased latency in the splash test without altering the locomotion in the open field. After administration of dexamethasone for an additional 7 days, treatment with Imipramine was able to reverse the increase in immobility in TSC and increase latency in the splash test. In conclusion, this data suggests that acute and repeated dexamethasone induces depressive-like effects which are reversed by conventional antidepressants and NOP antagonist (acutely). In addition to being an effective protocol in males and females for the induction of experimental depression caused by stress. Ultimately, these data provide evidence of the therapeutic potential of NOP antagonists in the treatment of depression.

9
  • MARIA JAQUELINE MONTE DE ANDRADE
  • Behavioral ecology of Hemidactylus agrius Vanzolini, 1978 e H. brasilianus (Amaral, 1935) (Squamata: Gekkonidae) in different phytophysiognomys of Caatinga in the Northeastern Brazil

  • Líder : ELIZA MARIA XAVIER FREIRE
  • MIEMBROS DE LA BANCA :
  • ELIZA MARIA XAVIER FREIRE
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • RAFAEL CAMILO LAIA
  • DANIEL CUNHA PASSOS
  • LEONARDO BARROS RIBEIRO
  • Data: 17-dic-2018


  • Resumen Espectáculo
  • Lizards have been widely used in studies of behavioral ecology across the world. Although species belonging to the Gekkonidae Family are known to be sit-and-wait foragers, studies have shown that some groups present modulations in the foraging behavior. In two native species of Hemidactylus that occurr in the northeastern region of Brazil (H. agrius and H. brasilianus), data about the trophic ecology demonstrate the presence of nutrition itens of low mobility, which are uncommon in the diets of species of sit-and-wait foraging type. Adding to that, information referring to activity profiles, termal ecology and thermoregulation behavior in those species remain unclear. Another relevant matter concerns to the distribution of those species across the domain of Caatingas, since, even though they occur in simpatry in highland areas, in some areas of the “Sertaneja Depressão” there is the presence of only one species, which could be related to the specificities in the use and sharing of resources. In this sense, this thesis has as objective to analyse the foraging and thermoregulation behaviors of Hemidactylus agrius and H. brasilianus, as well as the use of resources by both species in the Caatinga. For such reason, 18-day long excursions were taken in two areas of Caatinga with distinct traits, located in the municipalities of Lagoa Nova and Serra Negra do Norte, Rio Grande do Norte, Brazil. In the first area (“Caatinga Serrana”) both Hemidactylus species occurr in simpatry, while in the second (“Caatinga Stricto sensu”) one there is only the presence of H. agrius. Nocturnal active searches were carried out along preexisting transects (600m). For each registered animal, notes were taken about time, habitat and micro-habitat and behavioral observations were taken by focal-animal sampling method, during 10 minutes. After which the specimens were captured and body temperature (Tc), substract temperature (Ts) and air temperature (Ta) were assessed. Results showed that both species are foragers of the sit-and-wait type, remaining in stationary posture during most of the observed time with low activity rates (PTM ≤ 1,6%; MPM ≤ 0,3; e NAP ≤ 0,3).  In the diet analysis, 20 categories of prey were registered, where Orthoptera, Blattaria and Lepidoptera larvae were the main itens in both investigated areas. Furthermore, unprecedented cases of keratophagy and malocophagy were registered on both species of Hemidactylus. Seasonal differences in the diet were noted only on the H. agrius population in the ESEC Seridó; there were no sexual and interpopulational differences related to volume and number of consumed preys on the populations. Hemidactylus agrius presented a larger trophic niche and high values of overlapping between both species were obtained, especially when in sympatry. In relation to activity, both species are nocturnal with registered activity from 18:00h to 05:00h. Concerning the habitat use, H. brasilianus has used mainly areas of tree and shrubs vegetation, while H. agrius used mostly areas of rocky outcrops. The average body temperature (Tb) of H. brasilianus and H. agrius in activity in the highland area were the same at Tb = 22.8 °C and Tb = 23.2° C, while the Tb of H. agrius in the typical Caatinga was considerably higher (Tb = 26.2 °C); positive correlations were obtained between the body temperatures of the species and both environmental analysed temperatures (air and substract). In relation to the behavioral degree of thermoregulation, the values obtained from both species were relatively low (Δ < 1), indicating that the behaviors of both species have a low influence on the body temperature maintenance in those environments.

10
  • PAULYANNA MEDEIROS DE ARAUJO
  • influence of type of milking and the temperament of the cattle Gir breed and buffaloes Murrah breed on production and milk composition.

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • ANTHONIETA LOOMAN MAFRA
  • EBSON PEREIRA CANDIDO
  • FIVIA DE ARAUJO LOPES
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • VICTOR KENJI MEDEIROS SHIRAMIZU
  • VIVIANE DA SILVA MEDEIROS
  • Data: 27-dic-2018


  • Resumen Espectáculo
  • The studies  related to animal  behavior have increased in recent years, and are important because they allow better understanding of the causes that guide the actions of the animals  and allow for better planning in the implementation of more eficiente production systems.  Adding  to  this,  the  animal  welfare  has  received  increasing attention in the technical, scientific and academic means. The main reasons that lead people to be concerned with the farm animals welfare are concerns of ethnic origin, the potential effect it may have on productivity and quality of food and the links between animal welfare and international trade its products of animal origin. The study of the welfare is shown as complex and includes different aspects related to health and animal behavior and interactions that occur  between  these  aspects.  The  dairy  farming  is  a sector of animal production in which the human-animal interaction is of fundamental importance because of contact that establishes daily in carrying out routine activities. Among the factors that affect the behavior of cattle and buffaloes, stand out food, the weather and the adopted production  system. For lactating animals, the number of milkings,  production and time of milkings  are key conditions in their behavior patterns. Currently, the dairy Gir is the second breed in official milk control in Brazil, the first Brazilian zebu and dairy breed in the world. The Gir has established itself as breed adapted to the conditions of tropical Brazil, with good productive results. The Gir, as well as other Zebu breeds, tolerate higher ambient temperatures and can be managed  in  regions  with  these  temperatures  without  severe  impairment of milk production. Regarding the buffalo, one of the main points stand out these animals is the fact that the cost of production in general is not far from both the cost of cattle, as well as great adaptability to almost any kind of weather. In Brazil four breeds  are recognized, and the Murrah used in this research. The Murrah buffalos can be created in various weather conditions, often presenting as an option for the areas of use of the  property  to  which  the  cattle  do  not  fit.  The  buffalo  milk  has  a  different composition compared to cow's milk, and provides an output of oil products with high  commercial  value.  In  this  work,  the  Gir  cattle  and  Murrah  buffaloes  were exposed  to  two  different  types  of  milking,  manual  milking  and  subsequently mechanical tandem milking for Gir  and mechanical "espinha de peixe" milking and then milking carousel for Murrah buffalo.  The  aim  of  this  study  is  to  describe  the behavioral expression during routine milking in dairy cows of Gir and dairy buffaloes of  Murrah  and  identify  possible  changes  in  the  productive  and  nutritional characteristics of milk. The change in the milking routine and change the type of used milking can bring behavioral changes with influence on productivity. However, the two  races  presented  behaviorally  extreme  docility  that  was  reflected  in  an  easy adaptation  to  the  new  proposed  milking  system,  without  compromising  the productive aspects.

2017
Disertaciones
1
  • VITOR HUGO BESSA FERREIRA
  • Facing Stress: A Behavioral and Physiological Study of Captive Capuchin Monkeys (Sapajus Libidinosus)

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • NICOLE LEITE GALVAO COELHO
  • OLÍVIA DE MENDONÇA FURTADO PIMENTA
  • RENATA GONCALVES FERREIRA
  • Data: 24-mar-2017


  • Resumen Espectáculo
  • Considering the welfare of animals in captivity is findamental to take care of the physical and psychological health of individuals. However, despite several indicators available (eg, behavioral, biochemical and physiological), the integration of results still raises doubts about the actual state of well-being of an individual. In this paper we test the hypothesis that the incongruity between well-being indicators occurs because the animals within the same population differ in the way they behave and react to the stimuli. We used, as model, captive capuchin-monkey under the care  of CETAS de Natal / RN and Cabedelo / PB and the zoo of João Pessoa / PB. In the first chapter, we review several concepts and methodologies of the study of the animal personality. In the second chapter, we define the axes of the behavioral profile (GNB - Gender Normative Behavior) and stress coping (BPIS - Behaviors Potentially Indicative of Stress), and we verify if it is compatible with the physiological profile (Metabolites of Fecal Glucocorticoids - MFG) of animals in chronic stress of captivity. In the third chapter, we analyze whether the different behavioral types react to an acute stress of change of enclosure. Our main results were: Individuals who move more exhibit faster BPIS (eg head twirl), while more inactive individuals exhibit more stationary BPIS. At both ends of the activity-inactivity axis, the animals show physiological signs of low welfare. More sociable animals are more resilient, both physiologically and behaviorally level to chronic stress. After an acute stress, the individuals that score positively in the Sociability and Exploration axes exhibit better adaptation to the new environment. Our results corroborate models indicating the existence of different behavioral profiles that react differently to stress and that present physiological profiles. The pattern found resembles that described in other works for other species and may shed light on behavioral evolution and plasticity of the animal kingdom.

2
  • DENILSON ALVES HONORATO SILVA
  • The study of individual differences in horses (Equus caballus): comparing methodologies

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • MATEUS JOSÉ RODRIGUES PARANHOS DA COSTA
  • RENATA GONCALVES FERREIRA
  • VIVIANE DA SILVA MEDEIROS
  • Data: 27-mar-2017


  • Resumen Espectáculo
  • The study of individual differences in behavioral patterns of animals has gained prominence in the scientific literature. However, the forms of measuring these differences between individuals of different species are still being defined and tested. In this work we used two methodologies to assess individual differences in sport horses: a questionnaire with caregivers and behavioral tests. We tested two hypotheses: 1) questionnaire and behavioral test are identifying the same personality traits in animals; and 2) the behavioral profile will show temporal stability. The study was performed with 21 animals kept in the Vila do Cavalo stud farm in the city of São José de Mipibu, with 10 adult males and 11 adult females animals. It was possible to define two behavioral axes: Exploration/Safety and Activity/ReactivityAlert, as well as 5 axes through the questionnaire: Neurotic, Self-confident, Consciousness, Social and Nervousness. The Activity/Reactivity axis of the behavioral test exhibited a tendency to positively correlate with Consciousness, and the Exploration/Safety axis tended to correlate negatively with the Self-confident axis of the questionnaire. Among the 13 indexes created, the Alert was the only one to present a consistency over time, while animals considered as explorers, showed less explorations after four months. This low congruence between the indicators and the low consistency in the behavioral profile of the animals, when at the time of retest, questions the validity of the tested instruments and demands for new analyzes of the behavioral profile of horses.

3
  • MARIA LOUYSE DOS SANTOS LOPES
  • Cognitive bias in horses (Equus caballus)

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • MATEUS JOSÉ RODRIGUES PARANHOS DA COSTA
  • RENATA GONCALVES FERREIRA
  • VIVIANE DA SILVA MEDEIROS
  • Data: 04-abr-2017


  • Resumen Espectáculo
  • Studies on welfare show that several species of animals in worse emotional conditions exhibit learning and memory deficiencies as well as cognitive bias, in the sense of judging ambiguous stimuli as negative stimuli (ie they are pessimistic). However, most of these studies disregard the influence of the animal's personality at the time of testing. In this study we applied the methodology of cognitive bias tests to assess the emotional state of horses (Equus caballus) championship participants vaquejada, considered the stressing factor for the animals. We tested the hypotheses that: 1) animals in worse emotional state (indicated from the tests of cognitive bias) present worse performance in learning tasks of local discrimination and 2) the cognitive bias is influenced by the personality of the animal. The study was conducted with 21 adult animals, 11 males and 10 females, allocated in a hotel for horses and all submitted to training for sports activities, such as championships. We found that the pessimistic and optimistic profiles were predictive of learning and that more sociable animals with humans had better learning performance. Our work showed that the methodology of cognitive bias is an easy and fast applicability tool, demonstrating being able to assess emotional aspects relevant to animal learning and welfare. However, the personality of the animal needs to be taken into account to avoid false negatives.

4
  • JOAQUIM GONÇALVES DE AZEVEDO NETO
  • Effects of nociceptin/orphanin FQ receptor, Ro65-6570, on anxiety-related behavior in helpless mice

  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ELAINE CRISTINA GAVIOLI
  • VANESSA DE PAULA SOARES RACHETTI
  • MIRIAN GRACIELA DA SILVA STIEBBE SALVADORI
  • Data: 27-abr-2017


  • Resumen Espectáculo
  • Nociceptin/orphanin FQ (N/OFQ) is a heptadecapeptide, acting as an endogenous ligand of the NOP receptor. The NOP receptor has wide expression in the central nervous system and its activation induces inhibitory effects, causing reduction of neurotransmitters release and/or inhibition of neuronal firing, depending on the site (pre or post-synaptic) in which it is expressed. In vivo studies have showed the involvement of the N/OFQ-NOP receptor system in the modulation of emotional states. This study aimed to evaluate the effects of the NOP agonist, Ro65-6570, on the mouse behavioral changes after an uncontrollable stressful situation due to unpredictable electric footshocks. To achieve this aim, the learned helplessness model (LH) was used as a stressor to induce a helpless behavior. Helpless phenotype consists of a deficit in the escape behavior of the electrified compartment. Not all animals exposed to the LH developed the helpless phenotype, and then two distinct groups were observed: helpless and non-helpless mice. After the LH, tests were performed aimed to identify the behavioral changes induced by stress, such as elevated plus maze (EPM), forced swimming and open field. LH exposure induced anxiogenic-like effects in helpless mice. In fact, when compared to non-helpless and naive controls, helpless mice displayed decreased number of entries and time spent in the open arms of the EPM. After then, the effects of diazepam (1 mg/kg, via ip) and the NOP agonist, Ro65-6570 (1 mg/kg, via ip) were assessed in the anxiogenic-like behavior of helpless mice, as well as in spontaneous locomotion. Diazepam was able to reverse the anxiogenic-related behaviors of helpless mice in the EPM, without affecting locomotion. Similarly, the administration of Ro65-6570 induced anxiolytic effects only in helpless mice, without changes in the locomotor activity. In conclusion, this study supports to the N/OFQ-NOP receptor system as an innovative therapeutic target for the treatment of psychiatric disorders related to stress.

5
  • PRISCILLA VALESSA DE CASTRO ANDRADE
  • What does lies individual differences? Behavioral and physiological teste on Betta splendes

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • NICOLE LEITE GALVAO COELHO
  • RENATO HAJENIUS ACHÉ DE FREITAS
  • Data: 28-abr-2017


  • Resumen Espectáculo
  • According to environmental changes, the individuals present different strategies for coping with the varied external stimuli. The different responders comprise the different phenotypes that compose a population. These differences can be explained by endogenous changes, such as hormonal secretion. For instance, hormones modulate reproductive behaviors and cognitive processes. In order to characterize individual differences in a population, the present study aimed at testing the relationship between behavioral and hormonal profiles in a group of males Fighting fish, Betta splendens. A group of 86 males were observed for bubble nest construction, agonistic displays in conspecific contests and performance in a spatial learning protocol. After that, cortisol and testosterone plasma levels were measured. An innovative and stylish statistical procedure was applied to the data set in order to separate animal in groups related to its nest building behavior (k-means test) and then shown which behavioral and physiological parameters better explain the groups’ profiles (Random forest and Classification tree). Our results point to three distinct profiles: nest builders (nests of 30.74 ± 9.84 cm2), intermediates (nests of 13.57 ± 4.23 cm2) and non-builders (nests of 2.17 ± 2.25 cm2). These groups presented marked different in agonistic and learning behavior, as well as hormone levels. Cortisol was the main predictor prepared by the Random Forest test for the separation of individuals in the different groups (IG = 4.9; WMD = 94.5): nest builders and intermediates showed lower levels of cortisol while non-builders presented the highest basal cortisol values. The second most important predictor was learning performance, that separated animals from the intermediate from the nest builders (faster learners), followed by basal testosterone levels and agonistic behavior displays. While the testosterone levels were not significant to explain behavioral differences, it seems to be related to the construction profile. Our finding shows that different profiles invest differently in reproduction and that cortisol negatively influences nesting behavior and learning. In summary, our data suggest that different profiles in a population are determined by both hormonal and behavioral responses, and these differences confer flexibility to the population, allowing the presence of animals that invest the most in reproduction while other show defense and aggression as the dominant feature expressed.

6
  • RICARDO RODRIGUES AMORIM
  • Effects of alcohol on learning and on anxiety-like behavior in zebrafish

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • JANINE INEZ ROSSATO
  • RENATO HAJENIUS ACHÉ DE FREITAS
  • Data: 28-abr-2017


  • Resumen Espectáculo
  • Alcoholic beverages are popularly consumed in various human cultures. However, excessive and long-term alcohol consumption can promote social, physical and psychological damages that are difficult to reverse. In fact, alcohol has different effects on the body. Low concentrations promote euphoria, relaxation, and stress/anxiety relief (anxiolytic effect), and abstinence after chronic medial doses increases stress / anxiety (anxiety) and may interfere with learning. However, there is little information on how this drug alters cognitive and psychological aspects in stress/anxiety situations involving learning. Therefore, in-depth investigations are required with the proposition of translational animal models. As a result, characteristics such as: easy maintenance and reproduction in the laboratory, genetic homology superior to 70% to that of the human genome, and ease of administration of drugs, make zebrafish (Danio rerio) an ideal model in translational research involving drugs of abuse. In this sense, the present work sought to investigate the effect of different alcoholic treatments (chronic and acute) in the unfolding of the anxiety response and in the aversive associative learning of zebrafish.For this, the effects of alcohol in the aversive associative learning of zebrafish (article 1) and the effects of alcohol and environmental enrichment on the impossibility of the fish to avoid a stressor were tested (Article 2). The results indicated that anxiety-like behaviors in zebrafish are altered by changes in alcoholic concentrations, in the exposure regime or in the environment. Acute alcohol increases anxiety and potentiates the electroshock perception. While EE promotes anxiolytic effect and decreases the perception of electroshock. Finally, we suggest that this work serves as a basis for genetic and behavioral neurophysiological research regarding the effects of the interaction between drugs of abuse and environment.

7
  • JOAO CARLOS NASCIMENTO DE ALENCAR
  • Play a song, brain can dance as well: effect of rhythm structure of auditory tones over behavioral and electrophysiological parameters of arithmetic task performance

  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • BERNARDINO FERNANDEZ CALVO
  • DIEGO ANDRES LAPLAGNE
  • JOHN FONTENELE ARAUJO
  • Data: 09-may-2017


  • Resumen Espectáculo
  • Sequences of stimuli presented between 125-2000 ms (0.3-8Hz) may impact on perception, motor responses and cognition. Dynamic Attending Theory postulates oscillations of attention, that may synchronize by entrainment to rhythmic events from environment. Rhythm perception has been shown to involve classical motor areas, notably basal ganglia. These sub-cortical nuclei has been also linked to executive functioning, due to existence of cortical-striatum-thalamic-cortical loops. Since executive function is based on prefrontal cortex activity, this work aims to characterize effect of auditory rhythmic stimuli on motor behavior, executive function and electrophysiological responses. Sample (n=24) was previously calculated by G*Power 3.1 software. Participants were submitted to finger tapping and executive tasks (sequential arithmetic sum), while auditory tones were played or not. Our results show motor synchronization for ISI 500 ms, and increased variability for ISI 350 ms and 650 ms. Autonomic electrophysiological responses did not show any changes, except for a decreased heart rate at ISI 350 ms, Non-Synchronized Condition. Delta-Gama Modulation Index is negatively correlated with hitrate for ISI 350 ms, but positively correlated with hitrate at Synchronized Condition. ISI impacts on hitrate, but a larger modulation of both ISI and auditory stimuli over Reaction Time is shown. Our results suggest an “optimal entrainment range”, centered at 500 ms, and an increased likelihood for involuntary synchronization at this point. Besides, results suggest nervous system uses different cortical processing modes for different temporal requests from environment, consistent with a rhythmic mode.

8
  • SABINNE DANIELLE GALINA
  • Relation among light exposure in classroom, sleep-wake cycle and attention in adolescents of different regions of RN

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • FERNANDO MAZZILLI LOUZADA
  • JOHN FONTENELE ARAUJO
  • Data: 12-may-2017


  • Resumen Espectáculo
  • In adolescents, sleep phase delay is associated with reduced sleep duration, resulting in excessive diurnal sleepiness and low academic performance. This low performance may be related to the reduction in attention, cognitive process, whose components present circadian variation, and as well as the sleep-wake cycle (SWC) can be modulated by cycles of light-dark. Therefore, this study aims to verify the existence of relations between the lighting intensity in the classroom and the SWC, sleep quality, daytime sleepiness and attention in adolescents in the morning shift of private schools of the capital (C) (Natal: Latitude: 05º 47' 42" South, Longitude: 35º 12' 34" West) and from the interior (I) (Santa Cruz: Latitude: 6° 13' 46'' South, Longitude: 36° 1' 24'' West) of the RN‟s state. A total of 115 adolescents (C: 56 and I: 59), of both sexes (41 boys), enrolled in the freshman and sophomore years of high school, participated in the study. The students answered the questionnaires: "Health and Sleep", Pittsburgh Sleep Quality Index, Puberty and Phase Preference Scale, and Pediatric Daytime Sleepiness Scale, as well as a Sleep diary, which contained the Maldonado Sleepiness Scale, the latter for 10 days. Attention was assessed by the Continuous Performance Task (CPT), between 7:30h and 9:30h during school hours on a single application. The light intensity was recorded during the students' break time. The classroom was subdivided into 6 quadrants for measurement, which occurred with all lights on and also with the lights out and a projector on, simulating a projected class. In general, the sample had poor sleep habits and quality, partial deprivation and sleep irregularity between schooldays and weekends, regardless of where they live, showing that the start time of classes in the morning shift remains a challenge for adolescents. The individuals exposed to high light intensity within the classroom had earlier get up times (r = -0.30, p <0.001), later bedtimes (r = 0.23, p <0.05), and get up time irregularity (r = 0.20, p <0.05), and shorter time in bed during the week (r = -0.16, p = 0.05); As well as better attention performance through a higher percentage of correct answers (A) and lower omissions (O) for the tonic (A: r = 0.22, p <0.05, and O: r = -0.26, p<0.05) and phasic alertness (A: r = 0.22, p <0.05 and O: r = -0.23, p <0.05), and sustained attention (A: r = 0.17, p = 0 ,06 and O: r = 0.26, p <0.001). Thus, light intensity in the classroom can be a factor that influences sleep and attention components, such as tonic and phasic alertness and sustained attention; since those who attend classes in rooms with higher light intensity presented modifications in the sleep pattern and better attentional performance. However, additional studies with a larger number of schools in the localities studied are necessary to confirm this evidence.

9
  • CHRISTIAN CAMILO GARCÍA LÓPEZ
  • Freewill? Psychoneuroendocrine factors involved in the process of decision making under risk in young adult men

  • Líder : MARIA BERNARDETE CORDEIRO DE SOUSA
  • MIEMBROS DE LA BANCA :
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • NELSON TORRO ALVES
  • SIDARTA TOLLENDAL GOMES RIBEIRO
  • Data: 05-jun-2017


  • Resumen Espectáculo
  • Taking-risk behavior is under influenced of neuropsychological, neuroendocrine, social and individual factors, although there is still no clear consensus how much these aspects modulate the process of decision-making under risk. The present study evaluated the effect of psychological states, romantic partnership, and testosterone (prenatal and activational) and cortisol on the risk-taking behavior, as well as the reactivity of testosterone in the performance of risky task. University’ students between 21 and 30 years old (n = 49) participated in the investigation. The behavior towards risk was measured using a self-reported scale of risk propensity (EPR) and a task for decision-making under risk, Columbia Card Task (CCT). Multiple regression analysis shows a negative effect between low 2D:4D ratio, which indicates higher prenatal testosterone, and the attitude towards risk in the health/safety dimension of EPR, when plasmatic basal testosterone and cortisol were either low or high. Also, participants with high 2D:4D ratio, that indicates low prenatal testosterone exposition, showed more risky behavior on the CCT associated with high basal testosterone and low cortisol. Testosterone reactivity was associated to a better performance on CCT. Participants with higher scores for depression and anxiety were more likely to be involved in risky situations, and being in romantic relationships was associated with a higher aversion toward risk in the CCT. These results suggest that prenatal exposure to high levels of testosterone strengthens the attitude toward risk, signifying that activational testosterone seems not to be critical for the expression of this behavioral trait. On the other hand, lower levels of prenatal testosterone allow modulatory effects of activational testosterone on risky behavior depending on the context, and also promote following aversion towards risk to get a more favorable outcome. Furthermore, the findings of the present study suggest that not being involved in romantic relationship might account to have greater risk taking in favor of their reproductive strategies. It was also evidenced that under high-risk contexts young adult men with high depressive and anxious traits might show greater risky behavior.

10
  • JÚLIA ALBUQUERQUE AGUIAR
  • Assessing cognition in perimenopauses and surgical menopaused women: do sleep quality, mood and menopausal complaints predict cognitive performance?

  • Líder : MARIA BERNARDETE CORDEIRO DE SOUSA
  • MIEMBROS DE LA BANCA :
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • FABIOLA DA SILVA ALBUQUERQUE
  • TECIA MARIA DE OLIVEIRA MARANHAO
  • Data: 09-jun-2017


  • Resumen Espectáculo
  • General life expectancy has increased, which has provided to women around the world live about half of their adult lives after menopause, facing estrogen deficiency. Hormone deprivation evidenced in this period of life brings with it a great number of consequences for women, including cognitive deficit, changes in mood such as depression and anxiety, reduced sleep quality, and characteristic symptoms of this period, which includes hot flashes and facial flush, among others. Hence, this research aims to assess whether mood, sleep quality, menopausal complaints and surgical ovariectomy predicted the cognitive performance in perimenopausal women. Sixry-nine women were recruited in the Climacteric Clinic at the Januário Cicco Maternity-School, Natal-RN, Brazil. The assessment of cognitive performance occurred through tests of episodic memory, executive function and a questionnaire of memory complaints. Mood, sleep quality, comorbidities, menopausal complaints and surgical ovariectomy were analyzed as predictors of the cognitive performance. Comorbidities and menopausal symptoms data were collected in the participants’ medical records. The menopausal complaints were measured by the Blatt-Kupperman Index. The statistical analysis was conducted using general linear model and all data analysis was considered significant when P- value was &lt; 0.05. Higher anxiety and depression symptoms, as well as worse sleep quality, predicted executive function performance. Also, menopausal complaints and depression symptoms predicted memory complaints, but comorbidities did not predict cognitive performance. Surgical ovariectomy but not natural perimenopause predicted reduced episodic memory performance in women. The acute hypoestrogenism faced by surgically ovariectomized women indicates a fast change in cognitive performance, which may suggest the degenerative effect of hormonal absence and a preventive use of hormone therapy could possibly reduce this alteration, as supported by the critical windows hypothesis. In the perimenopausal transition typical physiological alterations are commonly found, as well as hypoestrogenism repercussions on cognition, mood and sleep quality. Hence, an integrated approach of those factors may improve life quality for the climacteric patients.

11
  • FLÁVIA SANTOS DA SILVA
  • Study of the acute effect of the active compounds of Banisteriopsis caapi and Psychotria viridis in common marmoset (Callithrix jacchus) as an animal model of juvenile depression

  • Líder : NICOLE LEITE GALVAO COELHO
  • MIEMBROS DE LA BANCA :
  • NICOLE LEITE GALVAO COELHO
  • BRUNO LOBAO SOARES
  • MARÍLIA BARROS
  • Data: 05-jul-2017


  • Resumen Espectáculo
  • The Major Depression (MD) is a worldwide mood disorder, reaching approximately 300 million people, capable of induce psychological, social and physiological impair, which in some cases can lead to death by suicide. 14% of young people aged 15-18 have DM that provoke attention and apprehension, since this phase consist an ontogenetic period of major brain modifications that last for the all lives. Currently, the most commonly used antidepressant treatment in all age groups is the pharmacological, although the new classes of antidepressants are more specific in their action, still have considerable side effects, take up to two weeks to initiate the desired therapeutic effects and induce low rate of remission. Thereby, there is a necessity to seek new pharmacological treatments for DM. In this scenario, have been tested some psychedelic serotonergic substances. The ayahuasca tea, a traditional Amazonian tea, has particularly drawn attention by its positive effects on health, both in the general population of users and in patients with mood disorders and drug addicts. To test the acute antidepressant action of ayahuasca was used Callithrix jacchus, a non-human primate that has already been considered an important model in biomedical studies, including mental disorders, because it´s more phylogenetic proximity to humans, has a well-defined etogram, invasive methods for measuring cortisol in feces, good adaptation in captivity and high fecundity rate. However, it was initially necessary to validate the species as a translational model of juvenile depression. For this, it was used the protocol of chronic social isolation that induced a physiological and behavioral depression-like state in males and females juvenile of C. jacchus, which was largely reversed by treatment with a classic antidepressant, nortriptyline (7 days). This study and its results are described in article I entitled " Common marmosets: A translational animal model of juvenile depression". Then was tested the acute antidepressant potential of ayahuasca tea in the previously validated translational model and after that we compared its efficacy with nortriptyline and placebo (saline). Thus, was originated the article II entitled " Acute effect of Ayahuasca tea on hormonal and behavioral parameters in common marmosets, as juvenile non-human primate model of depression". In both treatments was observed that (ayahuasca and nortriptyline) induced improvements in part of depressive-like symptoms, which was not observed with placebo. However, ayahuasca tea presented more effective antidepressant results than nortriptyline, since it started to revert symptoms faster, adjusted and lasting. Both studies presented here are of great relevance to the area, since in an unpublished way a translational model met all validation criteria, both traditional ones, such as; the etiological, face, functional and predictive, as well as the more recent criteria: inter-relational, evolutionary and population, thus enabling its use in complementary areas of investigation. In addition, it was emphasized not only acute antidepressant actions of the ayahuasca tea, but also more effective actions compared to the classic antidepressant, nortriptyline, thus corroborating in the validation process of this drug as antidepressant, stimulating new pharmacological investigations in this line that allow the consolidation of this substance as an antidepressant, since it has not shown tolerance to doses and nor long-term side effects in recreational users.

12
  • KAYO DIOGENES DE AZEVEDO SILVA
  • Decreased expression of melatonin MT1 and MT2 receptors in Specific areas of the central nervous system of rodents submitted to chronic treatment with Reserpine
  • Líder : ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • MIEMBROS DE LA BANCA :
  • FRANCISCO GILBERTO OLIVEIRA
  • JEFERSON DE SOUZA CAVALCANTE
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 31-jul-2017


  • Resumen Espectáculo
  • Parkinson's disease (PD) is a neurodegenerative disorder that mainly affects males with advancing age. PD is characterized by several motor symptoms such as tremors, bradykinesia, stiffness and postural changes. In addition to these, cognitive symptoms such as attention and memory deficits, dementia and mood changes are also present. It is also possible to notice a marked change in the sleep architecture of patients with PD. The hormone melatonin synthesized mainly by the pineal gland located in the thalamus is considered one of the hormones that induce the sleep phase of the organisms. Its action occurs after binding to specific receptors, MT1 and MT2. In the present study, 15 male Wistar rats (10 months) were divided into two groups called Control (CTR) and Reserpine (RES). These animals were submitted to a chronic protocol of 20 injections of reserpine, in order to create symptoms similar to PD. During the experimental protocol the animals were evaluated by catalepsy test. At the end of the treatment the animals were sacrificed and submitted to an immunohistochemical procedure to identify the MT1 and MT2 receptors in 5 areas of the central nervous system related directly to the sleep cycle and with more evident symptoms of PD, VLPO, SN and ZSPV. Our results showed that during the period of treatment the animals of the reserpine group presented a considerable and progressive motor deficit that were accentuated on days seven, eight, nine and ten of injections. Our immunohistochemical analyzes have shown that there is a significant reduction in the expression of melatonin receptors in the reserpine animals in all evaluated nuclei, however, new studies are necessary to better understand the real reason for this decrease in receptor expression and whether this decrease has a significant effect on Observed in patients with PD.

13
  • PÂMELLA CATHERINE SALLES SANTOS
  • Individual differences and player interaction in League of Legends

  • Líder : MARIA EMILIA YAMAMOTO
  • MIEMBROS DE LA BANCA :
  • CHARLES ANDRYE GALVAO MADEIRA
  • FIVIA DE ARAUJO LOPES
  • WALLISEN TADASHI HATTORI
  • Data: 14-ago-2017


  • Resumen Espectáculo
  • Electronic games are increasingly popular among people's leisure options. One of the game types that stands out the most today is the MOBA. This genre of game has as a proposition a dispute of two teams formed by 5 players each one whose objective is to conquer the enemy battlefield. However, when playing matches with people you do not know, it is extremely common to receive swearing and criticism about your choices and gameplay, as well as often encountering players who do not cooperate with the team to achieve the main goal, focusing much more on the intra-group dispute than intergroup, as the game proposes. Therefore the objective of this research is to investigate sociability traits, degree of individuality and risk-taking of the players to identify some probable issues that contribute to these observed behaviors. Participants were students of a technical and higher education institution of the masculine sex. Three stages of research were constituted. The first consisted of an online questionnaire covering sociodemographic information, game preferences and the psychological scales used in the study. The second stage consisted of attending a League of Legends match in an institution's computer lab. In the third stage the participants answered an online questionnaire informing the perceptions and behaviors observed during the match. The matches were recorded and watched. Each interaction of two or more players were labeled. The data obtained in the games with the previously applied scales were analyzed. The results showed that the participants' mean propensity to risk had an effect on the preference of game functions. Participants who presented lower death rates in the match have tended to present higher scores on Risk-Taking Scale. In addition, participants perceived less a contribution of time to the outcome of the match with the highest score in Vertical Individualism, indicating a greater desire to win or be the best. The results may contribute to the understanding of how expressions of individual differences are expressed in cooperative game environments.

14
  • RAFAEL HEITOR NUNES DE RUBIM COSTA
  • Comparative analysis of biological markers between men with and without clinical diagnosis of Posttraumatic Stress Disorder (PTSD)

  • Líder : MARIA BERNARDETE CORDEIRO DE SOUSA
  • MIEMBROS DE LA BANCA :
  • ANDRE GUSTAVO PIRES DE SOUSA
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • PAULA ADRIANA BORBA
  • Data: 16-oct-2017


  • Resumen Espectáculo
  • Posttraumatic Stress Disorder (PTSD) is a psychiatric condition characterized by the appearance of typical symptoms after exposure to a traumatic event, which can occur either directly or indirectly. The clinical presentation is of reliving the trauma, avoidance maneuvers of these intrusive memories, negative changes in cognition and mood, and symptoms of physical and psychic hyperreactivity. The chronic stress situation present in PTSD involves changes in the physiological mechanisms related to the hypothalamic-pituitary-adrenal (HPA) axis and to the autonomic nervous and immune systems. The literature shows no homogeneity regarding the findings indicative of the changes, demonstrating that the secretion profile of the hormone cortisol is high, reduced or unmodified, in studies involving participants with PTSD compared to a control group. A similar situation occurs with dehydroepiandrosterone-sulfate hormone (DHEA-S) as well as with the immune response associated with PTSD, evaluated by C-reactive protein (CRP). The present study was carried out with two groups of men, matched for age, 17 of them with clinical diagnosis of PTSD and 17 of the control group (without PTSD). The serum profiles of cortisol, DHEA-S, cortisol / DHEA-S ratio and CRP in the two groups were analyzed using non-parametric Wilcoxon-Mann-Whitney, Kruskall-Wallis and Spearman´s correlation coefficient. The statistical analysis considered the value of p <0.05. Results showed no statistically significant difference in any of these indicators between the two groups. Within the experimental group, when PTSD grades were stratified, DHEA-S levels were statistically lower in men with severe PTSD grade, when compared to the sum of the levels of participants with mild and moderate degrees. The Spearman´s correlation coefficient showed a negative association between cortisol levels and DHEA-S in the control group and, in the experimental group, a positive correlation between cortisol and CRP. These results suggest that the studied variables, alone, do not seem to be good markers for PTSD diagnosis, but when correlated, may reinforce this diagnosis. In addition, significantly lower levels of DHEA-S in severe PTSD suggest a decrease in the neuroprotective effect of this hormone and, consequently, the worsening of PTSD. The increase in the sample size could better characterize this alteration and if the reduction of DHEA-S could represent a marker for the diagnosis of PTSD severity.

15
  • JOSHUA MICHAEL MARTIN
  • Structural Differences in REM and Non-REM Dream Reports Assessed by Non-Semantic Speech Graph Analysis

  • Líder : SIDARTA TOLLENDAL GOMES RIBEIRO
  • MIEMBROS DE LA BANCA :
  • SIDARTA TOLLENDAL GOMES RIBEIRO
  • ADRIANO BRETANHA LOPES TORT
  • FERNANDO MAZZILLI LOUZADA
  • Data: 08-dic-2017


  • Resumen Espectáculo
  • The extent to which Rapid Eye Movement Sleep (REM) mentation may differ to that of non-REM remains an important area of enquiry in dream research. Previous studies have found that dream reports collected after REM awakenings are, on average, longer, more vivid, bizarre, emotional and story-like compared to those collected after non-REM. Despite this, a comparison of the word-to- word structural organisation of dream reports is lacking, and traditional measures that distinguish REM and non-REM dreaming may be confounded by report length. The analysis of speech as directed word graphs can be suitably applied, as it provides a structural assessment of verbal reports, while controlling for differences in verbosity. In the present study, we aimed to investigate the differences in the connectedness of dream reports and their approximation to a random-like structure through applying speech graph analysis to 125 mentation reports obtained from 19 participants in controlled laboratory awakenings from REM and N2 sleep. We found that: (1) transformed graphs from REM possess a larger connectedness compared to those from N2; (2) measures of graph structure can predict ratings of dream complexity, where increases in connectedness and decreases in their random-like nature are observed in relation to increasing dream report complexity; and (3) the Largest Connected Component (LCC) can improve a model containing report length in predicting sleep stage and dream complexity. These results suggest that REM dream reports have a larger connectedness compared to N2 (i.e. words recur with a longer range), which we interpret to be related to underlying differences in dream complexity. They also point to speech graph analysis as a promising method for dream research, due to its relation to dream complexity and its potential to complement report length in dream analysis.

Tesis
1
  • YWLLIANE DA SILVA RODRIGUES MEURER
  • Behavioural outcome and neurochemistry analysis of female and male Wistar rats early exposed to fluoxetine

  • Líder : REGINA HELENA DA SILVA
  • MIEMBROS DE LA BANCA :
  • REGINA HELENA DA SILVA
  • ELAINE CRISTINA GAVIOLI
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • ALESSANDRA MUSSI RIBEIRO
  • DEBORAH SUCHECKI
  • Data: 13-mar-2017


  • Resumen Espectáculo
  • Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed to treat depression, anxiety and other disorders. The developmental exposure to selective serotonin reuptake inhibitors (SSRIs) results in persistent behavioural impairment into adulthood. In this way, serotonergic overexpression in early life may lead to structural and functional changes in brain circuits that control cognitive and emotional behaviour. Here, we addressed the question of how postnatal (PN7-PN21) exposure to fluoxetine affects memory, anxiety- and depression- like behaviours, as well as neurochemical markers of interneurons and serotonergic cells in brain areas related to these behaviours in juvenile (PN45) and adult (PN90) female and male rats. In a first stage, we analysed both female and male rat’s performances in several behavioural tasks and investigated the expression of serotonin (5-HT) in the dorsal and median nucleus of raphe, and parvalbumin (PV) in PFCm and hippocampus at PN45. We found that early-life exposure to fluoxetine increased anxiety- and depression-like behaviours (more in female compared to male animals), and induced a working memory impairment only in the juvenile male. Afterwards, we performed behavioural and neurochemical analysis of male and female adult rats (PND90), where we found that fluoxetine affects only anxiety-related male behaviour. Also, the memory impairment (more in male than female) and depressive-like profile (both sexes) remained in adult age. Moreover, the exposure to fluoxetine affect PV immunoreactivity in the hippocampus in any sex at PN45 and PN90; however, adult animals appear to recover neurochemical deficits observed at the juvenile age. The results revealed developmental fluoxetine effects on juvenile behaviour that can have implications for affective disorders and mnemonic processes. These results revealed persistent changes a sex and age-manner related to developmental exposure to fluoxetine, where serotonergic modulation induce differential profile of anxiety-and depression-like behaviour and mnemonic impairment on female and male rats at juvenile and adult age. Also, suggest a sex-dependent compensatory mechanism, which it is possibly related to serotonergic sinalisation. Circuits may involve sub-cortical and cortical information processing, including subcortical limbic and possible (pre)frontal areas. Thus, our findings suggest that serotonergic modulation during critical periods of SNC development may alter the organisation of excitatory-inhibitory circuit and induce behavioural changes, which may have repercussions for the onset of neuropsychiatric disorders.

2
  • CLARISSA LOUREIRO CAMPÊLO BEZERRA
  • Polymorphisms in Alpha-synuclein Gene: risk for Parkinson´s disease and associations with motor and non-motor symptoms

  • Líder : REGINA HELENA DA SILVA
  • MIEMBROS DE LA BANCA :
  • GEISON DE SOUZA IZÍDIO
  • JEFERSON DE SOUZA CAVALCANTE
  • JOSE RONALDO DOS SANTOS
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • REGINA HELENA DA SILVA
  • Data: 14-mar-2017


  • Resumen Espectáculo
  • Increasing evidence indicate that genetic susceptibility contributes to the etiology of sporadic Parkinson´s Disease (PD). Genetic variations in SNCA gene, which encodes alpha-synuclein protein, are already well established in linkage and GWAS studies. Worldwide studies have find positive association of single nucleotide polymorphism (SNP) in SNCA and the increase risk for PD. In addition, variants in SNCA can influence individual traits or phenotypes of sporadic PD. The present study investigated associations between SNPs in SNCA gene and motor and non-motor symptoms of PD in a Brazilian population. 206 subjects (PD group= 105 and Control group = 101) participated in this study. The patients with PD were recruited from the neurology clinic of Onofre Lopes University Hospital, in Natal (RN, Brazil). We used questionnaires and scales to evaluate the healthy history, environmental factors, motor (Hoehn & Yarh e Unified Parkinson´s Disease Rating Scale), functional (Schwab & England), cognitive (Frontal Assessment Battery and Mini Mental State Examination) and emotional (Beck Depression Inventory and Beck Anxiety Inventory) aspects of the subjects. We also collected a blood sample to DNA extraction and genotyping of SNPs rs11931074, rs356219, rs2583988 and rs2736990. Regarding clinical assessment, the PD group presented motor impairment associated to a moderate decrease of functional capacity. The cognitive impairments were more evident in individuals with low education. Depressive and anxiety symptoms had a higher frequency and severity in PD group. All SNPs were more frequent in PD patients (p<0.05), and the associations of SNPs rs2583988, rs356219 and rs2736990 with increased PD risk were confirmed. The G-rs356219 and C-rs2736990 alleles had a significant higher frequency in patients with early onset PD. T-rs2583988, G-rs356219 and C-2736990 risk alleles were significantly more frequent in PD patients with cognitive impairments than controls in this condition. Furthermore, the presence of cognitive impairment was a predictor for PD in a logistic regression model. This study demonstrated for the first time an association of SNCA polymorphisms and PD in a South-American sample.

3
  • JULIA JENSEN DIDONET
  • Evaluation of biochemical parameters in two animal models os depression induced by learned helplessness and LPS administration.

  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ALIANDA MAIRA CORNELIO DA SILVA
  • BRUNO LOBAO SOARES
  • DANIELLE MACEDO GASPAR
  • ELAINE CRISTINA GAVIOLI
  • REGINA HELENA DA SILVA
  • Data: 15-mar-2017


  • Resumen Espectáculo
  • Major depression has a great impact on an individual’s quality of life and it is

    considered the leading cause of burden in terms of years lost due to disability. However,

    despite the severity of depression, the pathophysiology of the disease is still elusive. In

    this regard, the use of animal models plays an important role in research for the etiology

    of depression. This work compared biochemical alterations occurring on serum, pre-
    frontal cortex (PFC) and hippocampus in two animal models of depression: learned

    helplessness and administration of lipopolyssaccharide from E.Coli (LPS). Learned

    helplessness protocol used in this work resulted in 70 % of helpless mice, assessed by

    the inability to escape from electroshocks given 24 h or 48 h after the helpless-induction

    session. The other 30 % of mice were considered resilient. Helpless animals showed

    more oxidative damage in PFC and serum when compared to controls. No difference

    was seen between helpless and resilient groups, but there was a positive correlation

    between the oxidative damage on serum and PFC and helpless behavior. There was no

    difference in the concentration of IL-1β, TNFα, IL-6 and IL-10 cytokines on PFC and

    hippocampus of the animals exposed to the learned helplessness test, but there was a

    significant positive correlation between IL-6 concentration and depressive-like behavior

    on hippocampus. Indoleamine 2,3-dioxygenase (IDO) enzyme activity was not altered

    on learned helplessness model. Systemic administration of LPS (0,8 mg/kg) induced

    sickness behavior on animals characterized by decreased food and water intake, body-
    weight loss and altered body temperature 6 h after administration. Sickness behavior is

    over after 24 h, but LPS-treated mice displayed higher immobility time in the tail

    suspension test when compared to saline. There was more oxidative damage in serum,

    PFC and hippocampus of LPS group when compared to saline and controls. No

    differences on IL-1β and TNFα concentration on serum, PFC and hippocampus of the

    animals were detected, suggesting a transient nature of the LPS-induced inflammation.

    LPS-treated group displayed higher concentrations of IL-6 on PFC when compared to

    saline group, and IL-6 concentration positively correlated to depressive-like behavior.

    IL-10 concentrations on hippocampus were negatively correlated to depressive-like

    behavior and IDO activity was increased on PFC and decreased on hippocampus of

    LPS-treated mice. Data presented here corroborate for the hypothesis of immune

    activation during depressive episodes, then resulting in oxidative damage assessed in

    two animal models of depression. IDO activity behaved with some specificity in each

    animal model depending on the brain or systemic area.

4
  • BRENO TERCIO SANTOS CARNEIRO
  • Evaluation of Food Odor as a Temporal Cue in Rats Entrained to Food Availability

  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • CRHISTIANE ANDRESSA DA SILVA
  • JANE CARLA DE SOUZA
  • JOHN FONTENELE ARAUJO
  • MARIO ANDRE LEOCADIO MIGUEL
  • RHOWENA JANE BARBOSA DE MATOS
  • Data: 30-jun-2017


  • Resumen Espectáculo
  • The circadian rhythmicity presents itself as a common aspect in living beings, with the24 h light-dark cycle being its most obvious environmental synchronizer. The availability of food also constitutes an environmental synchronizer, which is evidenced in many species. In mammals, food entrainment is mainly characterized by increased locomotion, wakefulness and core body temperature in the hours before feeding. Convincing evidence shows that this anticipation is controlled by a true circadian oscillatory system, although its physical structure is unknown. The search for the physical substrate of the food-entrained oscillator has always been the main focus of the research in this area, and recent evidence shows that several brain regions seem to be involved in the synchronization by food. In recent years, in addition to the search for the neural substrate of this system, attention has been paid to its possible mechanisms of synchronization. In other words, what would be the signals responsible for the synchronization of the system. In this work, the objective was to investigate whether daily stimulation with food odor is a sufficient signal to induce anticipation in Wistar rats. The animals were kept in a light-dark cycle of 14h light and 10h dark with continuous recording of the motor activity inside wooden cabins. Four groups were used: Chow, Odor, Arousal and Arousal-Isolated. All were submitted to 10 days of feeding ad libitum (baseline). Subsequently, the Food Restriction (19 days) stage was started. Finally, all groups were submitted to Food Deprivation (2 days). The Chow group received two meals a day for one hour each, with 'Meal 1' in the 3rd hour of the light phase and 'Meal 2' at the 12th hour of the light phase. The Odor group received odor stimulation at the 3rd hour of the light phase ('Meal 1') and food at the 12th hour. The Arousal group was only stimulated (opening and closing the cabin) in 'Meal 1' and fed in 'Meal 2'. The Arousal-Isolated group was submitted to the same previous procedure, but was tested alone in the room. All groups presented intense anticipatory activity to 'Meal 2' (feeding). For 'Meal 1', the Chow group presented intense anticipation, the Odor and Alert groups presented mild anticipatory activity mainly
    during the first 10 days of stimulation, and the Arousal-Isolated group did not present anticipation. The results indicate that the odor stimulation is able to promote behavioral anticipation, but weakly, with habituation over the days. Similar responses between the Odor and Arousal groups are discussed considering the possible odor effect in the experiment room.

5
  • JENIFFER DA CÂMARA MEDEIROS
  • Acoustic communication in Neoponera villosa (Hymenoptera, Formicidae, Ponerinae)

  • Líder : ARRILTON ARAUJO DE SOUZA
  • MIEMBROS DE LA BANCA :
  • ADRIAN ANTONIO GARDA
  • ARRILTON ARAUJO DE SOUZA
  • MICHAEL HRNCIR
  • NICOLAS GÉRARD CHÂLINE
  • RONARA DE SOUZA FERREIRA CHÂLINE
  • Data: 31-ago-2017


  • Resumen Espectáculo
  • Acoustic and vibratory signals are used by several ant species in intraspecific and interspecific interactions, although studies concerning these signal modalities are scarce. Stridulation and drumming are among the main ways of producing vibroacoustic signals. These signals can transmit messages relative to alarm, distress, recruitment, attack, colony activation, clues for provisioning of larvae, evaluation of food resources and non-receptivity of females. The aim of this study was to investigate the use of acoustic signals in Neoponera villosa (Hymenoptera, Formicidae, Ponerinae). In order to achieve our aim, we characterized workers, gynes and males stridulation; we analyzed N. villosa colonies’ response to workers’ stridulation and evaluated the acoustic response of N. villosa colonies to nest disturbance. The results showed that stridulatory signals of N. villosa workers are composed mainly of monosyllabic chirp trains, with chirps composed of a single sequence of pulses. Nevertheless, the majority of the chirps produced by the reproductive castes presented a low amplitude pulse sequence preceding the main high amplitude sequence of pulses. These chirps were composed of two subunits and, thus, were identified as disyllabic chirps. The stridulatory signals presented significant differences among the N. villosa castes regarding the inter-chirp interval, the number of pulses per chirp, the inter-pulse interval and the pulse repetition rate. When exposed to workers’ stridulation, N. villosa colonies responded to the emission of stridulatory signals with behavioral pattern changes only if these acoustic signals were produced by nestmates. In nest disturbance context, N. villosa colonies did not respond with stridulatory signal emission, but with the emission of acoustic signals produced by drumming.

6
  • PATRÍCIA VIDAL DE NEGREIROS NÓBREGA
  • Participation of the homeostatic and circadian sleep components in functional performance among institutionalized elderly 

  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • ALVARO CAMPOS CAVALCANTI MACIEL
  • BRUNA DEL VECHIO KOIKE
  • CIBELE APARECIDA CRISPIM
  • JOHN FONTENELE ARAUJO
  • MARIO ANDRE LEOCADIO MIGUEL
  • Data: 11-dic-2017


  • Resumen Espectáculo
  • Introduction: Aging is one of the phenomena that affect the regulation of the sleep-wake cycle (SWC) and its components, the circadian and homeostatic. Disorders in the SWC regulation are related to an important health status indicator in the elderly population, the functional performance, whose progressive decline is known to be a usual Frailty Syndrome characteristic. Both pathological entities largely affect the institutionalized elderly, who are at greater risk of developing a faster deterioration process. Aim: Evaluate the influence of two sleep components, the homeostatic and circadian, on functional performance among institutionalized elderly. Materials and methods: Longitudinal study that lasted 24 months, with three evaluation procedures, conducted with 133 elderly people living in fourteen long-term institutions in the State of Paraíba, Brazil. The Pittsburgh Sleep Quality Index (PSQI) and actimetry (nonparametric approach) were used, in addition to specific questionnaires and tests to access variables in general health and functional performance (frailty phenotype). Descriptive statistics were used for sample characterization, with distribution measures for all variables. Then, bivariate analyzes were performed in order to observe associations between the independent and dependent variables, and the Effect-Size was calculated for each variable. Lastly, linear models of mixed effects were developed and adjusted by covariates in order to analyze whether changes in sleep quality (latency, duration, beginning as well as end of sleep, and PSQI score) and rest-activity rhythm (L5, M10, IS60, ISm, IV60 and IVm) would be predictors of frailty burden increase. Results: The sample was characterized by average age of 78.76 (± 7.62) years-old, poor sleep quality, PSQI (7.71 ± 4.38 points), and 47.3% of frail elderly. The frail elderly had worse sleep quality, PSQI = 9.00 (± 4.59), when compared to non-frail, PSQI = 6.42 (±3.74) (p = 0.001). The elderly with poor sleep quality complaints, prolonged sleep latency, inadequate sleep duration, low habitual sleep efficiency, nocturnal and daytime sleep disorders and/or use of sleeping medication displayed positive criteria for exhaustion, unintentional weight loss, decline in walking speed, grip strength and physical activity. In addition, it was observed a greater irregularity and fragmentation of the rest-activity rhythm among the frail elderly [ISm = 0.32 ± 0.14, p = 0.041) (IVm = 0.88 ± 0.23, p = 0.032), respectively]. Among the sleep quality variables, the PSQI global score was a predictor of frailty burden increase (β= 0.04, p = 0.003). And, of all rest-activity rhythm variables, only the intra-daily variability (IVm) was able to predict changes in frailty (β = 0.906; p = 0.034). Conclusion: Based on this longitudinal study results it was observed that poor sleep quality and rest-activity rhythm fragmentation were predictors of frailty burden increase among institutionalized elderly, that is, the homeostatic component was the main influencer of progressive decline in functional performance, concerning the frailty status. It should be noted that sleep-activity rhythm and sleep quality markers can be a new tool in monitoring the health and disease status in institutionalized elderly.

7
  • FELIPE DE OLIVEIRA MATOS
  • “C ≠ A+B” Face's Gestalt independent of cognitive demand: A study whith electrophysiological bases

  • Líder : ANTONIO PEREIRA JUNIOR
  • MIEMBROS DE LA BANCA :
  • ANTONIO PEREIRA JUNIOR
  • HINDIAEL AERAF BELCHIOR
  • GEORGE CARLOS DO NASCIMENTO
  • BRUNO DUARTE GOMES
  • GUILHERME DE ALENCAR BARRETO
  • Data: 15-dic-2017


  • Resumen Espectáculo
  • The phase-amplitude coupling (PAC) between the neuronal oscillations in the theta (3-6Hz) and gamma (30-90Hz) bands composes the basis of sensory integration, memory and attentional selection mechanism. In the present work, we present evidence through electroencephalography (EEG) that the AFA between theta and gamma in the prefrontal cortex (PFC) and posterior parietal cortex (PPC), respectively, is an underlying process in the perceptual closure in a recognition task holistic view of Mooney's Faces through the formulation of a Gestalt. The PAC tetha-gamma was quantified using the modulation index (MI). The role played by executive functions in this process was verified through logistic regression analysis with measures of general intelligence (IQ) performance and working memory test. The results show a lower MI when the faces are presented in the canonical position (left hemispheres 1.4 ± 0.3x10-3 and right 1.4 ± 0.4x10-3, p <.001 in both) in relation to vertically inverted faces (left hemispheres 2.5 ± 0.5x10-3 and right 2.7 ± 0.7x10-3).  However, the MI does not differ (p> .05) as to the success or failure to identify the images. No regression model tested allowed the prediction of success in the identification of faces based on measures of cognitive performance and MI. Thus, our study provides further evidence that PAC is adjacent to long-range communication between cortical areas and corroborates the discarding of the role of executive functions in supporting Gestalt's visual formulation in the parietal cortex.

2016
Disertaciones
1
  • IGOR FERNANDO COSTA FERNANDES
  • A música como moduladora na escolha de parceiros: um estudo sobre musicalidade e seleção sexual humana.

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • ALEXSANDRO LUIZ DE ANDRADE
  • WALLISEN TADASHI HATTORI
  • Data: 29-feb-2016


  • Resumen Espectáculo
  • A musicalidade humana é alvo de discussão das mais diversas áreas de conhecimento. Sua presença
    universal, datada de pelo menos 36 mil anos, bem como sua utilização cotidiana como ferramenta de expressão são alguns dos diversos argumentos que corroboram para a importância deste comportamento em nossa espécie. A musicalidade humana possui paralelos com atributos semelhantes em outras espécies de aves, cetáceos e primatas, nas quais esta característica tem sido
    estudada de forma sistemática desde às primeiras observações feitas por Darwin na composição da
    Teoria Evolucionista. A Musicologia Evolucionista se propõe ao estudo da função última da musicalidade humana, tendo como uma das hipóteses propostas para explicar a função do
    comportamento musical em nossa espécie a de que este estaria intrinsicamente ligado ao
    comportamento de seleção e escolha de parceiros. Dessa forma, buscamos investigar o efeito dos
    estímulos musicais, segundo sua qualidade, na seleção de parceiros sexuais, através de avaliação de estímulos fotográficos. Encontramos diferenças do efeito da música em homens e mulheres, sendo as mulheres mais responsivas às melodias apresentadas. Os resultados apontam também para um maior efeito de estímulos musicais de baixa qualidade, os quais interferem negativamente na percepção dos parceiros. Encontramos ainda diferentes efeitos segundo o valor de mercado dos
    parceiros potenciais apresentados. Por último encontramos diferentes efeitos dos estímulos musicais na avaliação das diversas variáveis avaliadas, tais como atratividade, inteligência, familiaridade, confiabilidade e interesse sexual despertado. A partir dos resultados obtidos encontramos evidências que corroboram com a hipótese de que o comportamento musical humano está ligado ao processo de seleção e escolha de parceiros sexuais.

2
  • JESSICA JANINE DE OLIVEIRA
  • Romance em baixo d'água: tipos comportamentais e escolha de parceiros em Betta splendens

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • FELIPE NALON CASTRO
  • HELDERES PEREGRINO ALVES DA SILVA
  • Data: 29-feb-2016


  • Resumen Espectáculo
  • Cada indivíduo apresenta uma respostas comportamental diferente diante de um desafio ambiental, muitas vezes mesmo quando comparado a outro indivíduo da mesma espécie, sexo e idade, essas diferenças são chamadas tipos comportamentais e quando consistentes ao longo do tempo caracterizam uma síndrome comportamental ou personalidade animal. Evidências apontam que a personalidade animal pode interferir na aptidão reprodutiva do indivíduo. Tendo isso em vista, no presente estudo machos e fêmeas adultos de Betta splendens foram observados em três contextos (exploratório, social e avaliação de risco), para identificar a existência de tipos comportamentais e diferenças entre os sexos nos tipos comportamentais nessa espécie. Os indivíduos foram classificados em três níveis em cada contexto: contexto social (social; intermediário e não-social), contexto exploratório (explorador, intermediário e não-explorador) e avaliação de risco (bold, intermediário e shy). Após essa classificação, machos sociais e nãosociais, exploradores e não-exploradores de coloração vermelha e azul foram utilizados no experimento de escolha de parceiro pelas fêmeas. Nossos resultados apontam que a maioria dos indivíduos testados possui fenótipos intermediários para os três contextos avaliados, e uma minoria de machos e fêmeas apresentaram tipos comportamentais. E a análise de correlação mostra que machos e fêmeas se comportaram de modo diferente em relação aos contextos. No experimento de escolha de parceiro, os resultados mostram que os tipos comportamentais da fêmea e do macho influenciam no processo de escolha de parceiro e que, mesmo na presença de pistas visuais (coloração corporal dos machos), o tipo comportamental continua sendo importante no processo de escolha.

3
  • JAQUELINNE PINHEIRO DA SILVA
  • Efeitos da privação de sono em tarefas cognitivas, usando o peixe paulistinha (Danio rerio) como modelo animal

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • JUDNEY CLEY CAVALCANTE
  • LIA REJANE MULLER BEVILAQUA
  • Data: 01-mar-2016


  • Resumen Espectáculo
  • Aprendizagem e memória são processos importantes paras as espécies, pois permitem o reconhecimento coespecífico, rotas e sítios de alimentação. Um dos comportamentos conhecidos por facilitar à aprendizagem é o sono, fenômeno universal presente na maioria dos vertebrados e altamente estudado sob vários aspectos. É sabido que a privação de sono altera processos fisiológicos e comportamentais nos animais, no entanto, sua função no organismo não é completamente compreendida. As hipóteses do papel do sono variam de conservação de energia à consolidação de memória, com variadas funções durante a evolução dos animais. O peixe paulistinha (Danio rerio) surgiu nos últimos anos como vertebrado modelo em genética e biologia do desenvolvimento, e rapidamente se tornou popular em estudos do comportamento, assim como aprendizagem e memória. Além de ser um animal de ritmo circadiano diurno e possuir comportamento de sono bem caracterizado, o peixe paulistinha ainda apresenta vantagens por seu tamanho pequeno e de baixo custo de manutenção, o que estabelece essa espécie como modelo interessante para pesquisas sobre sono. No presente estudo buscou-se analisar os efeitos da privação total ou parcial de sono sobre a aprendizagem, e ainda os efeitos concomitantes com o uso de álcool e melatonina. Para isso, o projeto foi dividido em 3 etapas, cada um com um tipo de condicionamento diferente: (1) Reconhecimento de objetos, (2) Aprendizagem aversiva baseada em punição e (3) Aprendizagem apetitiva baseada em reforço. Os resultados analisados mostraram que os peixes que foram parcialmente privados de sono e os totalmente privados de sono + álcool conseguiram realizar as tarefas igualmente aos grupos controle, no entanto, os peixes totalmente privados de sono e ainda os totalmente privados + melatonina apresentaram memória e atenção prejudicadas durante os testes. Por fim, nossos resultados sugerem que apenas uma noite de privação de sono é suficiente para afetar o desempenho do peixe paulistinha em tarefas cognitivas. Ademais, a exposição ao álcool na noite anterior ao teste parece suprimir os efeitos negativos da privação de sono, enquanto a melatonina parece não ser eficiente para promover o estado de sono, ao menos na metodologia aplicada aqui.

4
  • BÁRBARA DE ARAÚJO QUADROS CUNHA
  • Se eu quiser fumar, eu fumo, se eu quiser beber, eu bebo: A influência do álcool e da nicotina na aprendizagem associativa em peixe paulistinha (Danio rerio)

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • ELAINE CRISTINA GAVIOLI
  • JUDNEY CLEY CAVALCANTE
  • Data: 02-mar-2016


  • Resumen Espectáculo
  • O consumo excessivo de bebidas alcoólicas e tabaco é considerado uma das doenças mais devastadoras e dispendiosas atualmente, sendo responsável por inúmeros efeitos prejudiciais aos indivíduos e à sociedade. Dentre as áreas de investigação que abordam o consumo de álcool, muitas se preocupam em determinar os mecanismos de ação desta substância no encéfalo. Apesar de anos de pesquisa, ainda é pouco o conhecimento sobre os mecanismos pelos quais o álcool afeta as funções neurológicas e quais seriam as causas exatas das deficiências cognitivas e de memória relacionadas ao seu uso. Por outro lado, as ações da nicotina já foram bastante estudadas, e o mecanismo de ação melhor estabelecido. No entanto, o uso concomitante de álcool e nicotina ainda necessitam de pesquisas mais aprofundadas no sentido de se estabelecer como as drogas interagem no sistema nervoso e quais as consequências do uso combinado. Uma das principais funções do sistema nervoso é a capacidade de aprender e lembrar. Os reflexos condicionados são mudanças comportamentais, que podem ser aprendidas a partir de experiências repetidas. Essa aprendizagem pode sofrer alterações de acordo com mudanças fisiológicas e neurais, por exemplo, após o uso de substâncias psicoativas, como o álcool e nicotina. Devido à complexidade do sistema nervoso dos mamíferos e de suas respostas comportamentais variadas, outros modelos animais mais simples têm sido propostos, entre eles, o peixe paulistinha, Danio rerio. Neste trabalho, utilizamos esta espécie, com o objetivo de testar os efeitos de álcool, nicotina e álcool + nicotina no desempenho cognitivo do peixe na tarefa de aprendizagem associativa. Neste sentido, seis grupos foram testados: Controle (C00A00, n=13), Álcool 0,5% agudo (Ca00Aa0.5, n=9), Álcool 0,5% crônico (Ca0.5Aa0.5; n=13), Nicotina 50mg agudo (Ca00An50, n=13), Álcool 0,5% crônico + nicotina 50mg agudo (Ca0.5An50, n=15), Álcool 0,5% agudo e Nicotina 50mg agudo (Ca00Aa0.5An50 n= 7). Nossos resultados mostram que o peixe paulistinha é capaz de realizar tarefas associativas, mesmo sob ação de álcool 0,5% agudo, álcool 0,5% crônico, associação álcool crônico + nicotina 50mg agudo, Álcool 0,5% agudo e Nicotina 50mg agudo. No entanto, a nicotina (50mg) aguda interferiu negativamente na aprendizagem do animal. Nossos resultados sugerem que o peixe paulistinha consegue executar tarefas de aprendizagem associativa em labirinto em cruz. Ademais, os grupos expostos ao álcool e que receberam a associação do álcool e da nicotina, não tiveram o desempenho afetado com exceção do grupo que foi exposto somente a nicotina.

5
  • LAURA KYOKO HONDA
  • Ecologia do Movimento de Machos Cantores de Baleia Jubarte (Megaptera novaeangliae) no Sítio Reprodutivo de Abrolhos - BA.

  • Líder : RENATA SANTORO DE SOUSA LIMA
  • MIEMBROS DE LA BANCA :
  • EDUARDO MARTINS VENTICINQUE
  • MADRAS VISWANATHAN GANDHI MOHAN
  • MILTON CEZAR RIBEIRO
  • RENATA SANTORO DE SOUSA LIMA
  • Data: 03-mar-2016


  • Resumen Espectáculo
  • Estudos sobre movimentação podem fornecer diversos tipos de informações sobre a ecologia de diferentes grupos animais, desde padrões de uso de habitat até inferências sobre estados comportamentais. O presente trabalho tem como objetivo a caracterização dos padrões de movimentação em fina escala dos machos cantores de Jubarte em um sítio reprodutivo para detectar efeitos da abundância de machos cantores e da presença de embarcações. Adicionalmente, buscou-se verificar se é possível fazer inferências sobre os estados comportamentais dos cantores através das suas trajetórias. A coleta dos dados foi feita utilizando-se arranjos de gravadores acústicos autônomos desenvolvidos pelo Programa de Pesquisas em Bioacústica da Universidade de Cornell – EUA. O estudo foi realizado no sítio reprodutivo das baleias Jubarte do Pacífico Sul Ocidental localizado no Banco dos Abrolhos-BA durante a temporada reprodutiva de 2005. Os machos cantores de Jubarte foram identificados através da detecção dos seus sons por meio da inspeção visual dos espectrogramas das gravações. As posições dos cantores foram estimadas através da localização de cada som identificado com boa qualidade em pelo menos 3 dos 5 canais de áudio através de algoritmo customizado em ambiente MATLAB. Da mesma forma foi realizada a detecção dos eventos de embarcações. As trajetórias foram construídas a partir dos pontos de localização após uso do filtro Kalman. As trajetórias foram classificadas em categorias de abundância de cantores (baixa = até dois cantores e alta = a partir de três cantores) e de presença de barco (presença e ausência). Funções de distribuição de probabilidade foram construídas a fim de testarmos, por meio da análise de máxima verossimilhança, qual distribuição se ajustaria melhor aos nossos dados. Foi feita uma seleção de modelos concorrentes incluindo como modelos as categorias de análise (abundância e presença de barcos) e as funções de distribuição ajustadas aos dados. A variável preditora utilizada foi a velocidade. O melhor modelo foi escolhido com o Critério de Informação de Akaike corrigido para pequenas amostras (AICc). Os padrões de movimentação descritos diferiram de estudos prévios. Nossas categorias de análise não se mostraram boas para a explicar a variação dos dados, mas os modelos foram capazes de identificar dois padrões distintos de movimentação de machos cantores de jubarte: passos lentos e constantes caracterizando um estado comportamental exploratório intercalados por raros passos rápidos que caracterizam um movimento direcional. As motivações para a alternância entre os diferentes estados comportamentais provavelmente envolvem diferentes estratégias reprodutivas. Nossos resultados mostraram que trajetórias baseadas em dados acústicos podem ser utilizadas para a inferência de estados comportamentais distintos de baleias jubarte através da análise dos padrões de movimentação.

6
  • Francisco Edvaldo de Oliveira Terceiro
  • Cuidado parental diferencial em Callithrix jacchus em ambiente natural

  • Líder : ARRILTON ARAUJO DE SOUZA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • MARIA EMILIA YAMAMOTO
  • WALLISEN TADASHI HATTORI
  • Data: 03-mar-2016


  • Resumen Espectáculo
  • O cuidado parental é muito importante para aumentar a chance de sobrevivência da prole. Porém esse comportamento causa custos aos parentes implicando em um conflito entre pais e prole. Trivers (1974) enfatizou que pais devem otimizar o seu investimento para serem capazes de garantir a sobrevivência da prole atual e ainda serem capazes de ter mais proles no futuro. Por outro lado, infantes tentariam maximizar seus ganhos. Em espécies que são reprodutores cooperativos e possuem uma reprodução custosa esse conflito vai estar distribuido entre os membros do grupo. Como exemplo temos Callithrix jacchus, primatas que vivem em grupos de cinco a dezessete indivíduos, incluindo machos e fêmeas adultos assim como animais imaturos. Uma de suas características mais notáveis é que ajudantes contribuem para o cuidado da prole. O cuidado de comportamento parental parece ser influenciado por uma variedade de fatores tais como idade, sexo e experiência mas ainda não é claro como estes fatores interagem e determinam quando cada individuo irá contribuir. Portanto, é nosso objetivo estudar o investimento feito pelos cuidadores para os infantes em C.jacchus e analisar se existe cuidado parental diferencial em condições naturais. Nós estudamos uma grupo na Floresta Nacional de Assu durante doze meses e gravamos comportamentos de cuidado tais como carregamento, partilha de alimento, catação e amamentação de todos os indivíduos do grupo. Nós analisamos esse comportamento entre várias proles em um grupo familiar. Nós encontramos que o sexo dos cuidadores e dos filhotes só é relevante para o comportamento de catação e que a competição entre fêmeas em diferentes proles muda diretamente a alocação de cuidado para todos os comportamentos registrados e afeta a alocação de cuidado de todos os membros do grupo. Os resultados nos levam a concluir que não existe cuidado parental diferencial ao nível de indivíduo. Por outro lado, o cuidado parental e aloparental refletem a dinâmica social do grupo de C.jacchus e por essa razão podem ser usados com esse propósito como uma alternativa aos comportamentos agressivos e afiliativos.

7
  • CLARISSA DE ALMEIDA MOURA
  • Aprendizagem espaço-temporal e efeitos das condições luminosas no aprendizado do peixe paulistinha

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • MARIO ANDRE LEOCADIO MIGUEL
  • RODRIGO EGYDIO BARRETO
  • Data: 03-mar-2016


  • Resumen Espectáculo
  • Para processar a informação ambiental e perceber o tempo, os indivíduos utilizam-se de pistas ambientais, como luz e temperatura, que servem como guias para o relógio interno. O mecanismo temporizador endógeno é chamado relógio circadiano, o qual comanda uma grande variedade de ritmos diários bioquímicos, fisiológicos e comportamentais presentes nos organismos. Com isso, os animais podem antecipar eventos espaço-temporalmente distribuídos e usar essa informação para organizar as atividades diárias, o que é uma vantagem adaptativa para os indivíduos, já que muitos fatores ambientais apresentam variação circadiana. Aprendizagem espaço-temporal (do inglês: "time-place learning’’-TPL) é a habilidade de associar lugares com importantes eventos biológicos em diferentes horas do dia. Em nosso estudo utilizamos como modelo o peixe paulistinha (Danio rerio), conhecido por ser altamente social, para testar aprendizagem espaço-temporal baseada em reforço social. Além disso, objetivamos averiguar os efeitos das condições de claro constante e escuro constante na aprendizagem espaço-temporal, e se nessas condições, a atividade do peixe paulistinha é alterada. Para isso, testamos três diferentes condições (n=10): grupo claro-escuro (CE), grupo claro constante (CC) e grupo escuro constante (EE) durante 30 dias da seguinte maneira: diariamente, um grupo de 5 peixes paulistinha foi introduzido em um recipiente localizado no compartimento da manhã (um dos lados do aquário), às 8:00h e retirado às 9:00h, e em outro recipiente do compartimento da tarde (lado oposto do aquário), às 17:00h e removido às 18:00h, servindo como estímulo para que o peixe experimental ocupasse o compartimento onde o grupo fosse colocado. O comportamento foi filmado nos dois horários, 15 minutos antes e durante os 60 minutos de exposição ao estímulo, no 15º e no 30ª dia, porém neste último, os peixes foram filmados sem a presença do estímulo a fim de averiguarmos a aprendizagem espaço-temporal. Por fim, para saber a influência das três condições luminosas na atividade dos peixes, filmamos os últimos 6 dias de teste, para registrar o padrão de atividade. Nossos resultados mostraram que em ciclo claro-escuro (CE) o peixe paulistinha apresenta TPL, bem como é capaz de antecipar a hora e local do estímulo (grupo de coespecíficos), enfatizando a importância do estímulo social para a aprendizagem. Em condições de claro constante e escuro constante, o peixe paulistinha não apresentou aprendizagem espaço-temporal. Ademais, após 30 dias em condições luminosas constantes (claro constante e escuro constante), o peixe paulistinha mantém ritmo circadiano, porém em claro constante sua atividade é aumentada e seu ritmo atividade-repouso é alterado, através de um padrão de atividade distribuída homogeneamente ao longo das 24h, ao invés de concentrada na subjetiva fase clara, como nos grupos de ciclo claro-escuro e escuro constante, os quais conservam o padrão de atividade diurno da espécie.

8
  • LUANA CARLA DOS SANTOS
  • Irish Coffee: Efeitos de álcool e cafeína no comportamento e aprendizagem do peixe paulistinha.

  • Líder : ANA CAROLINA LUCHIARI
  • MIEMBROS DE LA BANCA :
  • ANA CAROLINA LUCHIARI
  • RAMÓN HYPOLITO LIMA
  • RODRIGO EGYDIO BARRETO
  • Data: 04-mar-2016


  • Resumen Espectáculo
  • Substâncias psicoestimulantes vêm sendo utilizadas de forma indiscriminada há muitos anos, e pouco se sabe os efeitos que elas causam a curto e longo prazo no comportamento geral, na aprendizagem e na memória. Essas substâncias são bastante usadas por jovens e adultos e elas possuem efeitos diferentes. Essas substâncias são dose dependente, caso consumidas em baixa quantidade agem como estimulante, aumentando a atividade locomotora, caso consumidas em alta quantidade, causam efeito depressor, diminuindo a atividade locomotora e/ou causando ansiedade. Poucos estudos vêm investigando os efeitos dessas substâncias na atividade locomotora, aprendizagem e memória e grande parte desses estudos são realizados em roedores. Peixe paulistinha é um modelo animal promissor para estudos comportamentais, cognitivos, ontogenéticos, dentre outros. Nossos objetivos foram determinar os efeitos do álcool, cafeína e de seu uso combinado com álcool, na atividade locomotora desses animais, usando para isso doses crônicas durante 27 dias e doses agudas durante um dia. Visto que pouco se sabe sobre os efeitos dessa exposição prolongada. Também investigamos os efeitos das substâncias em teste de reconhecimento de objetos, que se baseia na memória de único evento. Essas memórias são mais vulneráveis que memórias baseadas em várias repetições de eventos. Sendo assim, um teste adequado para utilizar com uso de substâncias psicoativas. Observamos que o uso crônico de cafeína provoca alteração na atividade locomotora dos animais, do mesmo modo, abstinência de álcool combinada com cafeína em dose aguda (dose média) provoca aumento de atividade locomotora. Quando submetidos a testes de memória, os animais exposto a doses altas agudas de álcool e em abstinência dessa droga têm prejuízo na formação e/ou resgate da memória. No entanto, tratamento com cafeína não prejudica a formação de memória. Animais expostos a tratamento com dose crônica moderada de álcool e dose aguda moderada de cafeína tem melhor desempenho na tarefa, indicando que dose aguda moderada de cafeína pode evitar os efeitos deletérios ocasionados pela abstinência do álcool. Em termos do comportamento geral, doses agudas de cafeína aumentam a locomoção, enquanto doses elevadas e a abstinência de cafeína induzem a comportamentos tipo-ansioso. A combinação álcool crônico e cafeína aguda induzem a alto comportamento tipo-ansiedade, enquanto a combinação cafeína crônica e álcool agudo diminuem tanto a locomoção quanto a ansiedade.

9
  • DANIEL SILVA POLARI
  • Conscious or Zombies – Self-Perception in Callithrix jacchus & Dinoponera quadriceps.

  • Líder : RENATA SANTORO DE SOUSA LIMA
  • MIEMBROS DE LA BANCA :
  • RENATA SANTORO DE SOUSA LIMA
  • MARIA EMILIA YAMAMOTO
  • JOSÉ ZAMORANO ABRAMSON
  • MILTON CEZAR RIBEIRO
  • Data: 04-mar-2016


  • Resumen Espectáculo
  • Consciousness, as a biological phenomenon, may consists of states of feeling, sensation or awareness. Specialized behaviour, sophisticated actions of communication, metacognition, social interaction, spatial orientation, the use of mental maps for navigation, and spatial memory, all point to conscious processing in genus other than Homo. This work aims to identify self-awareness states in two different species: using mirror self-recognition tests in Callithrix jacchus, and using selfperception tests in Dinoponera quadriceps. Displays of C. jacchus self-recognition using a mirror, were appraised with two protocols: no mark and with mark. D.quadriceps navigational capability displays during foraging trips to food resource, were appraised considering three different tests categories: (1) free access, (2) blocked by opaque object; and 3) blocked by clear object. Our results show selfperception in both studied species. With marmosets displaying contingency check behaviour to the specular image, self-observation, environmental exploration using the mirror as a tool and little, but significant mark reactions. Tocandiras were able to perceive its own location and to calculate short return paths to the colony after obtaining the food resource in all three types of tests. Here we provide further evidence of conscious states for species other than vertebrates.

10
  • JULIANA CAVALCANTE DE MOURA
  • A consolidação prévia de informação conflitante e não aversiva é necessária para a reconsolidação da memória de esquiva inibitória no hipocampo.

  • Líder : MARTIN PABLO CAMMAROTA
  • MIEMBROS DE LA BANCA :
  • LIA REJANE MULLER BEVILAQUA
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • MARTIN PABLO CAMMAROTA
  • Data: 22-mar-2016


  • Resumen Espectáculo
  • A reativação pode levar as memórias consolidadas a um novo estado de labilidade, tornando-as suscetíveis à incorporação de nova informação através de um processo de reestabilização dependente da expressão gênica e da síntese de novas proteínas conhecido como reconsolidação. A interrupção da reconsolidação usualmente produz amnésia. Contudo, algumas memórias são particularmente resistentes a agentes bloqueadores da reconsolidação, indicando que este processo ocorre somente quando é dada uma série específica de condições. Utilizando ferramentas farmacológicas e comportamentais, neste trabalho demonstramos que a consolidação prévia de informação não aversiva é essencial para a reconsolidação da memória de esquiva inibitória em ratos.

11
  • SILVANA SITA
  • Back to The Wild: Individual Differences in Capuchin Monkeys’ Rehabilitation and Relocation.

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • Hannah Buichannan-Smith
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • RENATA GONCALVES FERREIRA
  • Data: 04-abr-2016


  • Resumen Espectáculo
  • Primate populations in the wild have been rapidly declining mainly due to habitat destruction and to wildlife traffic to supply the illegal pet trade and biomedical research demand. As a result, wildlife rescue centers (in Brazil, CETAS) face a huge problem to allocate confiscated wildlife, which became accumulated in large numbers at their facilities. In Brazil, capuchin monkeys are the second most common primate species found at CETAS. Relocation of confiscated primates if well planned is a three-goal tool: help to achieve conservation; solve the problem of destination of confiscated primates and offer welfare condition to displaced wildlife. However, relocation projects have reported a great range of survival rates, being as low as 17% to 98%, so understanding the factors that are related to this disparity in survival rates would help us to achieve high success in primate relocation programs. In this work, we investigate the hypothesis that individual differences in capuchin monkeys are related to post-release survival and dispersal and responsiveness to rehabilitation process. Our research was based on two studies of relocated capuchin monkeys conducted as routine procedures of Brazilian environmental agency (IBAMA). The first (Pioneer Study) accompany the relocation  of 69 capuchin monkeys in lagoon islands Caatinga biome and the second (Detailed Study) accompany the relocation of 9 animals in the Atlantic Forest biome. At Chapter 1, we review the factors described in the literature which would be directly related to relocation success,  especially at individual level. In Chapter 2, two types of non-lexical approach to personality were assessed by behavioral codes: uncontextualized (UD) and contextualized (CD) personality  dimensions. Three UD (i.e. Exploration, Activity and Vigilance) and eight CD (i.e. Boldness, (food) Neophilia, Exploratory, Food orientation, Sociability, Aggressiveness, Activity, Vigilance) were used to classify individuals by score in two categories and then used to investigate trait- group difference in survivorship and dispersal/ habitat use. Chapter 3 was based in the second study (DS) and we analyze behavioral changes during different types of enrichment (i.e. physical, social, acclimatization and post-release) at three levels: group, individual and trait level (based on contextualized dimensions). Our major findings are: food Neophilia (positively) and Activity (negatively) CD related to individual survival after release, that is, more neophilic and less active individuals survived longer. Sociability related to higher dispersal after release and better learning at social enrichment. Enrichment is capable to promote survival skills  training and reduce stress, although different types of enrichment promotes behavioral changes differently; more neophilic individuals responded more to physical enrichment. We suggest that locomotion in captivity relates to anxiousness rather than a positive normal behavior. In conclusion, our findings indicate that individuals indeed respond differently to enrichment and post-release. Moreover, the personality traits such as food Neophilia, Activity, Sociability and Exploration seemed to be related to those different responses.

12
  • ANNARA YVE MOURA SOARES
  • Membrane properties of dentate gyrus neurons in mice lacking the DNA-repair enzyme Neil3

  • Líder : RICHARDSON NAVES LEAO
  • MIEMBROS DE LA BANCA :
  • RICHARDSON NAVES LEAO
  • EMELIE KATARINA SVAHN LEAO
  • OLAVO BOHRER AMARAL
  • Data: 05-abr-2016


  • Resumen Espectáculo
  • Esse estudo objetiva avaliar se a expressão da enzima de reparo de DNA Neil3 é importante para o desenvolvimento funcional dos neurônios. Estudos previos tem demonstrado que Neil3 interfere tanto na neurogênese adulta como na fazer embrionaria. Eu utilizei whole cell patch clamp para estudar propriedades sinapticas e de membrana das células granulares do giro denteado. O giro denteado é uma das regiões com maior expressão de Neil3 no cérebro e estudos previos tem demonstrado que a neurogênese reativa em camundongos adultos é afetada pela ausencia da enzima de reparo Neil3. Eu encontrei que a maioria das propriedades de membrana nas células granulares de camundongos knockout para Neil3 são normais com exceção à resposta de membrana às correntes de hiperpolarização e pós-hiperpolarização. Diferentemente de neurônios imaturos, as células granulares do giro denteado de camundongos com ausência de Neil3, na qual as correntes de hiperpolarização ativadas são geralmente as ultimas a aparecerem durante o desenvolvimento. Além disso, correntes sinapticas excitatorias foram similar em amplitude mas apresentaram um decaimento ligeiramente mais rapido em células de camundongos knockout de Neil3. Esses resultados podem indicar um balanço diferente entre os receptores AMPA e NMDA em camundongos knockout. Analises morfologicas de neurônios preenchidos com biotina e reconstrução post hoc não apresentaram grandes diferenças na morfologia dendritica entre animais controle e knockout. Esse estudo mostra que, em relação diferenças entre animais controle, neurônios do giro denteado de animais knockout de Neil3 não podem ser classificados como imaturos. Eu encontrei diferenças pontuais na corrente de hiperpolarização e pequenas diferenças em propriedades sinapticas. Ainda devem ser avaliadas se essas diferenças podem ser responsáveis por alterações comportamentais encontradas em camundongos Neil3-knockout. Além disso, estudos futuros utilizando marcadores de neurônios recém-nascidos são necessários para analisar o efeito da eliminação da enzima Neil3 no desenvolvimento de neurônios.

13
  • MARIA LUIZA CRUZ DE OLIVEIRA
  • Relação Entre o Uso De Mídia e os Hábitos De Sono, Sonolência Diurna e Cognição em Adolescentes de Escolas Privadas De NATAL/RN

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • FERNANDO MAZZILLI LOUZADA
  • JOHN FONTENELE ARAUJO
  • Data: 05-abr-2016


  • Resumen Espectáculo
  • O atraso de fase em relação aos horários de deitar e levantar na adolescência somado ao crescente uso de mídia pode ocasionar exposição à luz em horários  impróprios, irregularidade nos horários e privação de sono. Processos cognitivos básicos regulam o desempenho dos indivíduos. Nesse trabalho, avaliamos a atenção, a memória operacional e a flexibilidade cognitiva. Esses processos podem sofrer influência da irregularidade e da privação de sono, acarretando redução na performance cognitiva podendo prejudicar a aprendizagem. Nesse trabalho, verificamos se os hábitos de sono, a sonolência diurna e a cognição de adolescentes do turno matutino variam em função do uso de mídia. Assim, 83 estudantes (60 meninas, 23 meninos) da segunda série do ensino médio de escolas privadas de Natal/RN responderam questionários (A saúde e o sono, Avaliação do Cronotipo de Horne-Östberg e Escala de Sonolência de Epworth) e uma bateria de testes cognitivos (avaliação da atenção por uma Tarefa de Execução Contínua; memória operacional, pelo Subteste de dígitos; e Flexibilidade cognitiva pelo teste de trilhas e de Berg de classificação de cartas). Além disso, preencheram o diário do sono durante 10 dias (incluindo a pergunta “o que estava fazendo antes de dormir?”) e um protocolo diário de uso de mídia por dois dias na semana e dois no final de semana. No geral, o uso de mídia foi maior no fim de semana em relação à semana, e o dispositivo mais utilizado foi o celular, seguido de televisão e computador. Não foram encontradas correlações entre a estimativa de uso semanal de mídia e os parâmetros relacionados ao sono. Contudo, foram encontradas correlações fracas entre a estimativa semanal de uso e: a estabilidade geral na atenção (r=-0,23; p<0,05), os pontos (r=0,22; p<0,05) e escore total (r=0,22; p<0,05) na ordem direta do subteste de dígitos, e os erros únicos (r=-0,26; p<0,01) do teste de Berg. Em relação à frequência de uso de mídia antes de dormir, a televisão aparece como o dispositivo preferido pelo grupo que mais usa mídia neste horário (G3). De forma geral, os horários de deitar e levantar diferiram entre os dias de semana e fim de semana, mas não houve diferença na irregularidade nos horários de deitar e levantar em função do uso de mídia antes de dormir. Foram encontradas diferenças nos horários de levantar no fim de semana, de modo que o grupo com menor frequência de uso de mídia antes de dormir (G1) levantou mais cedo (Anova, p<0,01 –Bonferroni, p<0,05). A maioria dos estudantes apresentou sonolência diurna excessiva, com diferenças nas proporções entre os grupos. Porém, os maiores percentuais foram observados sucessivamente no G1 e G3 (X2, p<0,05). Quanto ao desempenho nos testes cognitivos, o G1 apresentou menor percentual de omissões no alerta fásico (Mann-Whitney, p<0,05), uma tendência a um menor percentual de omissões em relação à atenção sustentada (Kruskal-Wallis, p=0,06), maior número de pontos na versão indireta do subteste de dígitos (Mann-Whitney, p<0,05) e uma tendência a ser mais eficiente na versão A do teste de Trilhas (Mann-Whitney, p<0,05). De maneira geral, esses resultados corroboram nossas hipóteses de que o uso de mídia influencia o sono, a sonolência diurna e a performance cognitiva, principalmente quando a utilização dos dispositivos eletrônicos ocorre próximo ao horário de deitar. Porém, estudos adicionais com um maior número de indivíduos são necessários para confirmar estas evidências.

14
  • GALILEU RODRIGUES BORGES
  • Caracterização Dos Hábitos De Sono, Sonolência Diurna e Qualidade Do Sono em Professores Universitários Das Áreas Biomédica e Tecnológica. 

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • FERNANDO MAZZILLI LOUZADA
  • MARIO ANDRE LEOCADIO MIGUEL
  • Data: 06-abr-2016


  • Resumen Espectáculo
  • A expressão do Ciclo Sono/vigília é resultante de interações entre características individuais, conhecimentos e hábitos de sono, e o ambiente social. Em estudos com professores do ensino fundamental e médio, foi observada má qualidade de sono e sonolência diurna em metade da amostra, além de privação de sono. Dessa forma, é importante uma investigação em professores universitários, que além da docência, desenvolvem atividades de pesquisa e extensão acumuladas a funções administrativas. O objetivo desse trabalho foi caracterizar de forma comparativa os hábitos e conhecimentos sobre o sono, a qualidade de sono, sonolência diurna de professores de uma instituição de ensino superior das áreas Biomédica e Tecnológica. Estes aspectos foram avaliados por meio dos questionários: 1. Sono e Saúde, 2. Índice de qualidade do sono de Pittsburg, 3. Escala de Sonolência de Epworth, e 4. Avaliação do cronotipo de Horne e Ostberg (HO). Além disso, o padrão de sono e vigília e os horários de trabalho foram registrados por meio do 5. Diário de sono e do 6. Protocolo de atividades diárias preenchidos durante 10 dias. Participaram da pesquisa 86 professores, sendo 44 (23 mulheres) da área biomédica e 47 (14 mulheres) da área tecnológica. O horário de início de trabalho (BM: 9:53h ± 1:30h; TC: 10:05h ± 2:30h) e a duração do trabalho na instituição (BM: 7:30h ± 1:27h; TC: 7:30h ± 1:28h) não diferiram entre as áreas (ANOVA, p > 0,05). Porém, o horário de fim de trabalho foi mais tardio em professores da área tecnológica (BM: 18:10 ± 1:35 h; TC: 18:48 ± 1:24 h – ANOVA, p < 0,05). A carga horária total de trabalho tendeu a ser maior em professores da área biomédica (ANOVA, p = 0,06). Associado a isso, houve uma maior carga horária em ensino em programas de pósgraduação e número de orientandos nesta área (ANOVA, p < 0,05). Professores da área biomédica apresentaram um percentual maior de acertos nas questões sobre o conhecimento sobre sono, acompanhado de melhores hábitos de higiene do sono (X2 , p < 0,05). Os horários de dormir (BM: 23:53h ± 15min; TC: 23:31h ± 22min) e de acordar (BM: 6:46h ± 40min; TC: 7:40h ± 30min), e o tempo na cama (BM: 6:58h ± 60 min; TC: 7:12h ± 55min) não diferiram entre as áreas (ANOVA, p > 0,05). Embora os professores da área biomédica tenham apresentado uma tendência à matutinidade em relação aos professores da área tecnológica (X2 , p < 0,05). Quanto à qualidade de sono e sonolência diurna, há um percentual maior de boa qualidade acompanhado de um percentual menor de sonolência diurna excessiva na área biomédica (X2 , p < 0,05). Essas diferenças nos parâmetros de sono podem estar relacionadas a melhores hábitos de higiene do sono e conhecimento sobre o sono nos professores da área biomédica. Dessa forma, sugere-se que a área de atuação profissional influencie os conhecimentos sobre o sono impactando os hábitos de sono, produzindo efeitos na qualidade e na sonolência diurna de professores universitários. Esse quadro reforça a necessidade de realizar programas educacionais sobre o sono com professores universitários na tentativa de promover melhores hábitos de sono e consequentemente melhor qualidade de vida, saúde e produtividade acadêmica nesses profissionais.

15
  • THAMIRES CASAGRANDE
  • The Rhythm of Male humpback vocal activity

  • Líder : RENATA SANTORO DE SOUSA LIMA
  • MIEMBROS DE LA BANCA :
  • RENATA SANTORO DE SOUSA LIMA
  • JOHN FONTENELE ARAUJO
  • SIMONE ALMEIDA GAVILAN
  • ARTUR ANDRIOLO
  • Data: 07-abr-2016


  • Resumen Espectáculo
  • Many studies of vocal activity of humpback whales have focused on investigating the temporal and geographical pattern changes in the male song. This knowledge can contribute to the species management, explaining how the behavioral traits are modulated by external factors of the environment in which the individual is inserted. This knowledge associated with information about the life history, biology and ecology of the species, provides the development of more successful conservation measures. Determining the existence of a periodic pattern of vocal activity of male humpback whales along the breeding season may support the hypothesis of endogenous biological rhythms, or how the biotic or abiotic zeitgebers could modulate the expression of the vocal behavior of these animals, which is so important for their reproductive success and maintainance of a increasing and healthy population. The aim of this study was to verify the existence of such rhythm in the occurrence of male vocal displays in the vicinity of the National Marine Park of Abrolhos. For this, we used acoustic data previously collected during the years 2003, 2004 and 2005. In 2005 the effort was divided into two areas, a treatment area where whale watching boat traffic is frequent similar located in the same general area to the previous years and a control area with rare boat traffic. The recordings were visually and aurally inspected every 2 minutes using XBAT an application that runs in MATLAB. These 2-minute samples were categorized as: presence or absence of humpback vocal activity and also vessel noise. Spectral analyzes were performed using Cosinor and a correlation test through a routine developed in MATLAB. Our results show the existence of a vocal activity pattern for all years in the treatment area, but not in the control area. Vocal activity concentrated between 15:00 pm and 10:00 am. The same pattern was not observed in all months of 2005 in the control area where the boat traffic is reduced. Coincidentally, the temporal pattern of vessel noise was highest between 10:00am and 15:00pm revealing a negative correlation with male vocal displays. Motorboat noise not only mask humpback male vocal displays but also the endogenous rhythm of vocal activity of humpback whales. Because of the masking caused by motorboat noise in male vocal displays, they avoid higher sound intensity schedules, organizing themselves in time.

16
  • NARA PAVAN LOPES
  • Acoustic variability in Guiana dolphins (van Benédén, 1864) 

  • Líder : RENATA SANTORO DE SOUSA LIMA
  • MIEMBROS DE LA BANCA :
  • RENATA SANTORO DE SOUSA LIMA
  • ARTUR ANDRIOLO
  • FERNANDA SCARANO CAMARGO
  • Data: 08-abr-2016


  • Resumen Espectáculo
  • In communication a signal is transmitted by a sender and can carry information about its identity, size, sexual status, ability to fight and to survive. Multiple factors can interfere with this communication, varying the output signal as a result of variation in the environment, body size, social learning and cultural transmission. Acoustic signals may vary within species between populations. Dialects are signal variations of two populations that can exchange genes and geographic variation micro- or macro-geographic, depending on the distance, occurs when individuals from different populations don’t mix. These terms are not well established in the literature and are often considered the same or used errouneously, thus a revision was made to clarify the terms involved in acoustic variation. A standardization of terms is proposed and clear deffinitions presented based on the processes that may or may not be related to the evolution of variability. Odontocetes (toothed whales, Order Cetartiodactyla) use acoustic communication in the mediation of social interactions, to obtain food and to navigate. One of the main sounds produced by dolphins in their interactions is the whistle (frequency modulated tonal sound). This study aimed to compare whistles of estuarine dolphins (Sotalia guianensis) collected in Baía Formosa, RN (6o 22' S; 35° 00' W) with published data from other sites in Latin America. The results show significant correlations between maximum and end frequencies as well as between initial and minimum frequencies in Baía Formosa as well as in all other places, indicating a preponderance of frequency ascending whistles used by the species along its distribution. The duration had a significant negative correlation with the initial frequency at all locations tested (p <0.00001 and r = 0.71) and suggests a physiological threshold for high frequency whistles. The principal component analysis divided sites into two major groups, but the discrimination was not related to latitudinal variation. Sampling differences (equipment with distinct sample rates) and analyses with different parameter values likely resulted in different results. Other likely explanations are: variations due to the environment, presence and percentage of calves in the data samples (producing higher frequency sounds) or larger animals (emit lower frequencies) and social vocal learning.

17
  • GUSTAVO ALEXANDRE BRAGA DE CARVALHO
  • Evaluating the influence of biotic and abiotic factors on the selection of visual color signals in Gymnophitalmidae lizards of coloured tails

  • Líder : DANIEL MARQUES DE ALMEIDA PESSOA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • RAFAEL CAMILO LAIA
  • Data: 27-abr-2016


  • Resumen Espectáculo
  • The coloration can peform a variety of functions among the various groups of animals, and, especially in lizards, this functional variability is relatively high, may act for exemplo as reproduction signaling, social signal and anti-predations strategy. Thus, the color adopted by the species may vary depending on the characteristics of the environment (e.g. Illuminant and background) and biotic factors (e.g. visual system of the observer), so that different colors are selected in according to the sensory environment in question. The aim of this study was to test the hypothesis of sensory drive in the tail coloration of two species of lizards gymnophitalmideos (Vanzosaura multiscutata and Micrablepharus maximiliani). For this were conducted collects samples in three different ecosystems (Caatinga, Sandbank and Atlantic Rain Forest) and in two different seasons (rainy and dry season). The color of the animals, as well as the surrounding substrate and the solar light spectrum was measured by a spectrophotometer and these information were inserted in a visual modeling for lizards and potential predators. The results showed peaks of the UV light in the surfaces of the two species measured, which may be responsible to increase contrast to animals with UV vision. The phenotype of lizard was the one that showed best results in detection of the tail of these two species. On the other hand, the other parts of the body, would supposedly have camouflage function, because of their low contrast with the substrate. We also found a variation of the color contrast between the animal and substrate for different visual phenotypes found in different observers. Therefore, it is concluded that the intraspecific communication may be the main factor affecting the conspicuous coloration of the tail of the two species. Moreover, the blue and red color may exert different functions at certain times. With the red tail fulfilling camouflage function to lizards, for example.

18
  • PHIETICA RAISSA RODRIGUES DA SILVA
  • Empatia e reciprocidade em ratos Wistar: um paradigma para avaliar comportamento pró-social

  • Líder : MARIA EMILIA YAMAMOTO
  • MIEMBROS DE LA BANCA :
  • FLAVIO FREITAS BARBOSA
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • REGINA HELENA DA SILVA
  • Data: 04-may-2016


  • Resumen Espectáculo
  • O comportamento pró-social se refere a quaisquer ações que têm a intenção de beneficiar outros, independente do ator também se beneficiar no processo. O termo é bastante amplo e abrange vários subcomponentes, tais como cooperação, mutualismo, altruísmo e ajuda. A cooperação geralmente traz um custo para o indivíduo cooperador que resulta na diminuição da sua aptidão. Embora isto pareça contraditório com a teoria da seleção natural, mecanismos que favorecem a evolução da cooperação foram selecionados, tais como a seleção de parentesco, a reciprocidade direta e a reciprocidade generalizada. Por trás do comportamento pró-social pode estar um componente emocional motivador, tal como o sentimento de empatia. A empatia é a capacidade de experienciar reações afetivas ao observar a experiência do outro (empatia emocional), partilhando o seu estado emocional, e ser capaz de adotar o ponto de vista do outro (empatia cognitiva). Ainda não há um modelo animal estabelecido para o estudo da empatia como motivador do comportamento pró-social, em seus diversos aspectos. Dessa forma, utilizamos um protocolo que propõe avaliar empatia e comportamento pró-social em ratos (Bartal et al., 2011) visando verificar sua reprodutibilidade e buscando compreender aspectos como ajuda e cooperação (reciprocidade direta e generalizada) bem como motivação para esses comportamentos. O comportamento de ajuda foi avaliado a partir da libertação de um colega aprisionado, pela abertura da porta de uma caixa restritora. A posterior retribuição da ajuda foi o parâmetro utilizado para investigar reciprocidade para um rato conhecido (direta) ou não (generalizada). Os ratos não recebiam treinamento ou recompensa pela tarefa. Reproduzimos os resultados do protocolo original e verificamos a presença de reciprocidade, porém não pudemos distinguir a direta e da generalizada. Identificamos outros fatores associados com a abertura da porta. Vimos que os animais continuavam abrindo a porta quando submetidos a um teste com a caixa restritora vazia, após ter aprendido como abrir a porta. Vimos também que os ratos “libertadores” entravam na caixa após abertura e permanenciam nela a maior parte do tempo durante o teste. Quando os ratos foram submetidos previamente à caixa vazia e depois à caixa com um coespecífico não houve abertura em nenhuma das circunstâncias, indicando um possível efeito de hábito sobre o comportamento. Sendo assim, é necessário investigar os demais fatores que possam estar envolvidos com a abertura da porta antes de considerar o uso do paradigma aqui estudado para investigação de mecanismos relacionados à empatia e ao comportamento pró-social.

19
  • CINTHYA MONTENEGRO DE VASCONCELOS SILVA
  • Avaliação do perfil de sono-vigília em um modelo crônico de roedor para a doença de Parkinson

  • Líder : ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • MIEMBROS DE LA BANCA :
  • JOSE RONALDO DOS SANTOS
  • MARIO ANDRE LEOCADIO MIGUEL
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 13-may-2016


  • Resumen Espectáculo
  • A doença de Parkinson (DP) é uma desordem neurodegenerativa e progressiva com espectro clínico variado. Além dos sintomas motores clássicos também podem surgir complicações não-motoras, destacando-se aí problemas cognitivos, psiquiátricos e autonômicos. Evidências demonstram que tais sintomas não-motores frequentemente precedem o aparecimento dos sinais motores e são extremamente relevantes, dado o impacto negativo que causam na qualidade de vida dos indivíduos. Os sintomas não-motores podem apresentar múltiplas causas, dentre as quais uma possível disfunção do sistema circadiano. Dessa forma, diversos processos fisiológicos influenciados pelo sistema de temporização circadiano (STC), como o ciclo sono/vigília podem se mostrar alterados em pacientes acometidos pela DP. O STC é responsável pela geração e manutenção dos ritmos circadianos, que são oscilações endógenas manifestadas pelos seres vivos em diversos processos fisiológicos e comportamentais, com período em torno de 24 horas. Assim, é fundamental a compreensão dos efeitos da progressão do processo patogênico da DP sobre o perfil circadiano do ciclo sono/vigília e também de componentes do STC, em particular no núcleo supraquiasmático (NSQ), o principal marcapasso do sistema. No presente estudo, ratos wistar jovens (6 meses) e de meia-idade (10 meses) foram submetidos a um modelo animal crônico de DP com administração de reserpina durante 20 dias. Ao longo do tratamento foram realizadas análises comportamentais do sono, bem como a avaliação motora dos animais. Após o fim do tratamento, foram realizadas análises imunoistoquímicas no NSQ dos animais. Nossos resultados mostraram que o tratamento crônico com reserpina promoveu comprometimento motor progressivo tanto nos animais jovens quanto nos de meia-idade. Além disso, as análises comportamentais revelaram perturbações no ciclo sono/vigília dos animais tratados em comparação aos indivíduos controle, incluindo avanço na fase de sono e aumento na fragmentação do sono. As análises imunistoquímicas não permitiram observar efeitos significativos do tratamento com reserpina sobre a composição neuroquímica do NSQ, contudo novos estudos são necessários para a avaliação neuroquímica e morfométrica desse importante marcapasso circadiano na DP.

20
  • VANESSA CARLA COELHO DE LIMA
  • The Immaturity period in capuchin monkeys (Sapajus sp.): social network and foranging skills

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • RENATA GONCALVES FERREIRA
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • BRISEIDA DOGO DE RESENDE
  • Data: 23-may-2016


  • Resumen Espectáculo
  • The study of development has been highlighted with the growing acceptance of new models that argue that behavioral processes can play an important role in the origin and maintenance of phenotypic variation. This perspective is particularly relevant in the study of species living in socially and ecologically complex environments, because is during development that individuals improve appropriated behavior for survival in the
    face of immediate conditions. We evaluated the changes in social redes and changes in patterns of foraging and obtaining food in immature capuchin monkeys, specifically analyzing the following hypotheses: 1. Infants exert widespread attraction to other members of the group; 2. The social relations of lactating females are mediated by market forces; 3. The feeding behavior efficiency increases with development; 4. Social proximity acts as a facilitator in foraging behavior. We used data collected from a group of capuchin monkeys (Sapajus sp.) inhabitants of the Tiete Ecological Park (PET) (about 20 ha), located on the east side of São Paulo and composed of 26 individuals. The observations were made between the years 1999 and 2001, totaling 304 hours, 18,081 scans of behavior and proximity, and 1568 behavioral sequences. Infants were the most tolerated among all immature, having the highest levels of reach and strength in their proximity redes, while juveniles from the second year of life received significantly more aggressive approaches. These results support the evidence high tolerance to individual infants. However, the results do not support the model that the lactating females´
    interactions follow market rules, because these females both received and offered more grooming. In the analysis of feeding behavior we detected changes in obtaining food strategies, with infants making use of breastfeeding; Juveniles I, getting food scrounging from foraging conspecifics; and juveniles II and III gradually increasing the percentage of time dedicated to handling the food by themselves. Infants were more central than at later ages, and efficiency at this age correlated to centrality. Consistently, the centrality not correlated to foraging efficiency in juvenile over 2 years. Nowadays, for many species the rate of environmental changes exceeds the capacity of animals to adapt to new conditions. Knowing that most of behavioral plasticity occurs during development, social tolerance for maintenance of group cohesion and for learning foraging skills is
    crucial for survival of young individuals.

21
  • LAURA CAROLINA AHUMADA HERNÁNDEZ
  • EMOTIONAL STIMULATION EFFECT ON SENSORY PROCESSING AUDITORY
     
     
  • Líder : JOHN FONTENELE ARAUJO
  • MIEMBROS DE LA BANCA :
  • JOHN FONTENELE ARAUJO
  • KATIA CRISTINE ANDRADE
  • NELSON TORRO ALVES
  • Data: 24-may-2016


  • Resumen Espectáculo
  • Emotions are crucial for the survivor of the organisms. They allow individuals to recognize what is threatening and what is safe in the environment. Emotions work modulating several cognitive processes, such as perception, attention and memory. At an electrophysiological level, emotions influence the response of neuronal networks measured by Event-Related Potentials (ERP). It has been documented that pleasant and unpleasant pictures increase the amplitude of the visual ERP in the visual areas of the brain. However, little is known about how emotions affect the processing of stimuli of different sensory modalities. The aim of this work was to test how the International Affective Picture System (IAPS) may affect the ERP of an innocuous sound. For this purpose the auditory ERP of 36 healthy students was recorded while they were watching a stream of high arousal unpleasant, high arousal pleasant, neutral images or a white screen. Heart rate variability (HRV), subjective self-report and band frequency power were measured too. Results showed that subjective self-report of the pictures emotional property verified the emotional qualities of these pictures, but it was slightly different form the Brazilian standard scores. We also found a deceleration of the HRV during emotional pictures viewing, and this correlated with the subjective self-report. No effect from emotional valence on the auditory ERP was found, only an effect of the pictures when compared to the white screen condition. In the left hemisphere, band frequency power showed a increase of theta and alpha power in the first moment for the four conditions. In a second moment, there was a increase of the power of this two bands during emotional pictures presentation in the right hemisphere. And then, it was seen a decrease in the right hemisphere of theta band power during unpleasant picture viewing. Scores from the subjective self-report and HRV confirmed that IAPS are a good method to elicit and evaluate emotions, but is necessary to extend the Brazilian standardization to have a more reliable instrument. Findings in the auditory ERP suggest a division of attention between the two kind of stimulation. Finally, the increase in the theta and alpha band power, especially in the right hemisphere, throughout the temporal series suggest a specialization of right hemisphere in the processing of emotional information.

22
  • DEISYLANE GARCIA DA SILVA
  • Information flow on the regulation of the foraging activity of Dinoponera quadriceps

  • Líder : ARRILTON ARAUJO DE SOUZA
  • MIEMBROS DE LA BANCA :
  • ANA MARIA MATOSO VIANA BAILEZ
  • ARRILTON ARAUJO DE SOUZA
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • Data: 29-jul-2016


  • Resumen Espectáculo
  • Social interactions between workers in a colony do not happen randomly, since workers decide how often they will interact and who they will interact with. Interactions rate in the colony are regulated by the density of individuals it contains and through which can quickly transfer information in the colony, causing changes in network dynamics. In order to analyze the flow of information among workers of Dinoponera quadriceps we investigated two colonies based on the number of workers and larvae in the nest, number of individual interactions, number of outputs, 'strength' and 'reach of each interaction, and also the information flow at different times. The study was conducted in the Behavioral Biology Laboratory at UFRN. Two colonies with different densities of workers were observed for 16h/colony, totaling 8 hours/day by recording using a digital camera. Colonies of D. quadriceps showed no correlation between the total number of interactions with the total number of workers nor to the number of nest exits. The per capita rates of interactions showed a similar pattern in both colonies, being higher during the food availability periods. The colony with lower density of workers had more interactions per individual, especially on the day and period with food, and these interactions got stronger and greater range. The dynamics of social networks also showed a similar pattern among colonies, with greater flow of information during the feeding time. Based on these results we conclude that workers of D. quadriceps regulate foraging activity through self-stimulation, as well as with their contact rates by increasing the number of interactions when food was offered to the colony, changing the flow of information and increasing dissemination of information.

Tesis
1
  • LAILA DA SILVA ASTH FERNANDES
  • Efeitos in vivo e in vitro de agonistas parciais do receptor NOP: implicações para o tratamento da ansiedade, depressão e mania

  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ELAINE CRISTINA GAVIOLI
  • GIROLAMO CALO''
  • JOHN FONTENELE ARAUJO
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • THEREZA CHRISTINA MONTEIRO DE LIMA
  • Data: 26-ene-2016


  • Resumen Espectáculo
  • Introdução: Este trabalho investigou os efeitos de dois agonistas parciais peptídicos, UFP-113 e [F/G]N/OFQ(1-13)NH2, e um agonista parcial não peptídico, AT-090, do receptor NOP no comportamento emocional de camundongos, bem como as vias de transdução do sinal decorrentes da ligação destas moléculas com o receptor NOP. Métodos: Foram utilizados camundongos machos, das linhagens Swiss e CD-1, além dos nocautes para o receptor NOP (NOP(-/-)) e seus controles selvagens NOP(+/+). O labirinto em cruz elevado (LCE) foi utilizado para avaliar o efeito dos compostos sobre a ansiedade. O diazepam e os agonistas do receptor NOP, N/OFQ e Ro 65-6570, foram utilizados como controles positivos no LCE. Os camundongos NOP(+/+) e NOP(-/-) foram utilizados na avaliação da seletividade de ação dos compostos com efeito do tipo ansiolítico. O teste da natação forçada (TNF) foi utilizado a fim de se avaliar os efeitos dos compostos sobre o comportamento do tipo depressivo. A nortriptilina e os antagonistas do receptor NOP, UFP-101 e SB-612111, foram utilizados como controles positivos no TNF. As ações da N/OFQ, UFP-101, SB-612111, UFP-113, [F/G]N/OFQ(1-13)NH2 e AT-090 foram ainda avaliadas no teste de hiperlocomoção induzida pelo metilfenidato (HIM), onde o valproato foi utilizado como controle positivo. A influência do UFP-113 e [F/G]N/OFQ(1-13)NH2 na atividade locomotora foi testada no campo aberto. As vias de transdução do sinal (proteína G e β-arrestina 2) dos agonistas (N/OFQ e Ro 65-6570), do antagonista (UFP-101) e dos agonistas parciais (UFP-113, [F/G]N/OFQ(1-13)NH2 e AT-090) do receptor NOP foram investigadas por meio da avaliação da transferência de energia por ressonância de bioluminescência (BRET). Para isso, foram usadas células co-expressando o receptor NOP acoplado à luciferase (doador de energia), e a proteína verde fluorescente (aceptor de energia) acoplada a uma das proteínas efetoras: proteína G ou a β-arrestina 2. Resultados: Diazepam (1 mg/kg), N/OFQ (1 nmol), Ro 65-6570 (0,1 mg/kg) e AT-090 (0,01 mg/kg) apresentaram efeito do tipo ansiolítico no LCE. Os efeitos do Ro 65-6570 e do AT-090 foram devidos a ativação seletiva do receptor NOP, uma vez que ambos foram inativos em camundongos NOP(-/-) expostos ao LCE. Em contraste, UFP-113 e [F/G]N/OFQ(1-13)NH2 foram inativos no LCE. No TNF, nortriptilina (30 mg/kg), UFP-101 (10 nmol), SB-612111 (10 mg/kg), UFP-113 (0,01 e 0,1 nmol) e [F/G]N/OFQ(1-13)NH2 (0,3 e 1 nmol) apresentaram efeito do tipo antidepressivo, diferentemente do AT-090, que foi inativo neste teste. Os efeitos do UFP-113 e do [F/G]N/OFQ(1-13)NH2 foram devidos a ativação seletiva do receptor NOP, uma vez que o pré-tratamento com N/OFQ preveniu o efeito do tipo antidepressivo de ambos. O metilfenidato (MF, 10 mg/kg) induziu hiperlocomoção nos camundongos expostos ao campo aberto, que foi prevenida pelo valproato (400 mg/kg). A N/OFQ (1 nmol), assim como UFP-113 (0,01-0,1 nmol) e [F/G]N/OFQ(1-13)NH2 (1 nmol), foram capazes em reduzir a hiperlocomoção induzida pelo MF, sem alterar a locomoção per se. O efeito do UFP-113 decorreu da ativação seletiva do receptor NOP, uma vez que foi inativo em camundongos NOP(-/-) expostos ao teste da HIM. Em contraste, o UFP-101 (10 nmol), assim como SB-612111 (10 mg/kg) e AT-090 (0,001-0,03 mg/kg) não alteraram o aumento na locomoção induzido pelo MF. Tanto o UFP-113 quanto o [F/G]N/OFQ(1-13)NH2 induziram hipolocomoção nas maiores doses testadas (1 e 3 nmol, respectivamente). In vitro, tanto a N/OFQ quanto o Ro 65-6570, promoveram a interação do receptor NOP com a proteína G e com a β-arrestina 2 de forma concentração-dependente, comportando-se como agonistas plenos do receptor NOP em ambas as vias de transdução. O AT-090, UFP-113 e [F/G]N/OFQ(1-13)NH2 promoveram a interação do receptor NOP com a proteína G com efeitos máximos significativamente reduzidos em relação a N/OFQ. O AT-090 foi capaz de induzir o recrutamento da β-arrestina 2 novamente com efeitos máximos reduzidos em relação a N/OFQ, enquanto o UFP-113 e o [F/G]N/OFQ(1-13)NH2 falharam em induzir o recrutamento da β-arrestina 2. Portanto, AT-090 se comportou como agonista parcial em ambas as vias de transdução, enquanto UFP-113 e [F/G]N/OFQ(1-13)NH2 se comportaram como agonistas parciais e antagonistas, respectivamente, nas vias de transdução da proteína G e da β-arrestina 2. O UFP-101 não promoveu o recrutamento da proteína G, nem da β-arrestina 2, se comportando como antagonista do receptor NOP em ambas as vias de transdução. Conclusão: Ligantes do receptor NOP que produzem o mesmo efeito na interação do receptor NOP com a proteína G (agonismo parcial), são capazes de induzir efeitos opostos no recrutamento da β-arrestina 2 (agonismo parcial vs antagonismo). Essas diferenças no recrutamento da β-arrestina 2 podem promover efeitos distintos sobre a ansiedade e o humor, como foi verificado nos testes comportamentais. Este trabalho corrobora o potencial do receptor NOP como uma ferramenta farmacológica inovadora no tratamento de transtornos emocionais.

2
  • VICTOR KENJI MEDEIROS SHIRAMIZU
  • Stress response system, attachment, and sociosexuality: a psychophysiological analysis of the life history strategies

  • Líder : FIVIA DE ARAUJO LOPES
  • MIEMBROS DE LA BANCA :
  • FIVIA DE ARAUJO LOPES
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • MARIA EMILIA YAMAMOTO
  • ALEXSANDRO LUIZ DE ANDRADE
  • OLÍVIA DE MENDONÇA FURTADO PIMENTA
  • Data: 02-mar-2016


  • Resumen Espectáculo
  • Stress response system is essential to an optimal energetic allocation to the different physiological systems and coordinated behavioral responses during psychosocial and physical challenges. Such allocation is also a central core in Life History Theory, which seeks to explain how and why individuals “decide” to allocate energy and time in somatic or reproductive effort (e.g. mating or parenting effort). Recent theoretical approaches seek to understand how early life experiences can shape the stress response system and their behavioral (e.g: attachment and sociosexuality) and physiological outcomes in adulthood, which are associated with life history strategies. Besides, scholars have hypothesized these components can interact in a functional ways. In study I, it was sought to validate an attachment measure, it was translated and adapted to Brazilian context, showing appropriate indices of reliability. Through study II, distinct physiological reactivity patterns during a psychosocial stressor were found based on basic dimensions of attachment styles and sociosexuality. Erotic videos were presented to participants (study III) and individual differences in cortisol reactivity and habituation response in skin conductance were explained by attachment and sociosexuality. Lastly, study IV showed that differences in marital satisfaction could be explained by attachment-related avoidance and sex specific differences in the overall magnitude of the cortisol response. Thereby, these studies contribute to understanding how early life experiences reflect in different behavioral strategies and physiological profiles underlying the Life History Theory, which could be activated in a context dependent way.

3
  • PATRÍCIA CRUZ BARBALHO
  • Dinâmica social e movimento coletivo em éguas (Equus caballus)

  • Líder : RENATA GONCALVES FERREIRA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • ERICA CRISTINA BUENO DO PRADO GUIRRO
  • FIVIA DE ARAUJO LOPES
  • MATEUS JOSÉ RODRIGUES PARANHOS DA COSTA
  • RENATA GONCALVES FERREIRA
  • Data: 31-mar-2016


  • Resumen Espectáculo
  • Este trabalho analisa a dinâmica social de um grupo de éguas em três dimensões: diádica, triádica e coletiva. Está dividido em três capítulos cujos objetivos são: 1) descrever interações diádicas afiliativas e agonísticas e caracterizar a dinâmica social de parcerias preferenciais, 2) analisar ocorrências e interações em conflitos (intervenções de terceiros) e pós-conflitos (reconciliação, consolo e apaziguamento) e 3) caracterizar a dinâmica de movimentos coletivos sob análises de fatores próprios do indivíduo (idade, peso, ranque e estado reprodutivo). O estudo foi realizado no Haras Volta (Frei Paulo, SE, Brasil) em 2012 e 2013. Foi observado um grupo de 64 éguas e 20 potros lactentes da raça manga-larga machador. Foram realizadas três tipos de observações diurnas: 1) focal (ocorrências de comportamentos agonísticos, afiliativos, sincronia e mudança de direção = 130 horas); 2) todas as ocorrências de conflitos em 304h e 3) varreduras (posicionamento e atividade = 117 varreduras) que geraram informações de proximidade (valor da relação), rede social e distâncias entre os animais. No Cap. 1 descrevemos que as éguas se envolveram mais em afiliação do que em agonísmos. É possível que a sincronia na direção possa ser um tipo de afiliação também nessa espécie. Éguas mais velhas e mais pesadas tiveram ranques mais elevados, mas não houve categoria mais agressiva que outra. Parceiras preferenciais apresentaram similaridade em idade, peso, força nos relacionamentos e centralidade social sendo que a dinâmica social dessas parcerias caracterizou-se por proximidade e baixo agonísmo entre parceiras. A afiliação e a sincronia foram mais direcionadas para animais neutros do que para parceiras preferenciais. No Cap. 2 reportamos que reconciliação, consolo/apaziguamento e intervenção em conflitos (IC) ocorreram em 57%, 37% e 31% dos conflitos, respectivamente. A ocorrência de reconciliação ou dispersão, realizadas pelas díades com e sem reconciliação, respectivamente, podem ser estratégias para redução da incerteza/instabilidade social pós-conflito. Os conflitos ocorreram entre éguas com pouca proximidade e reconciliação não foi dependente do valor da relação (amizade), mas o consolo e apaziguamento foram. A intervenção em conflitos foi realizada por éguas com idade e ranque mais elevados que os das oponentes do conflito, e não foi direcionada a parceiras preferenciais, sugerindo manutenção da estabilidade social. No Cap. 3 detectamos que não houve uma categoria de indivíduos que se posicionasse com maior frequência à frente ou ao centro do rebanho. Animais mais jovens (potros) foram socialmente mais centrais e animais com necessidades nutricionais diferenciadas (prenhes e lactantes) e de alto ranque foram menos centrais socialmente. Mais da metade do rebanho esteve direcionado, com antecedência, para o sentido que o grupo veio a seguir e o índice de concordância na direção (ICD) foi maior quando o grupo se deslocou mais. Isso pode sugerir que o sentido do deslocamento do grupo foi determinado pelo sentido do corpo da maioria dos animais (minimizando custos de consenso), que pode ter ocorrido por processo mimético de sincronização, sugerindo uma forma simplificada de coordenação (liderança) distribuída em pastejo. Éguas vazias e de baixo ranque ajustaram mais suas direções em pastejo à direção das outras éguas. Isso indica maior ocorrência de processos miméticos de sincronismo, o que pode levar a coordenação do movimento ser efetuada por animais que mantenham maior consistência na direção.

4
  • ANNA CECILIA QUEIROZ DE MEDEIROS
  • Comportamento de craving alimentar em população brasileira

  • Líder : MARIA EMILIA YAMAMOTO
  • MIEMBROS DE LA BANCA :
  • FELIPE NALON CASTRO
  • FERNANDA RODRIGUES DE OLIVEIRA PENAFORTE
  • FIVIA DE ARAUJO LOPES
  • JORGE TARCISIO DA ROCHA FALCAO
  • MARIA EMILIA YAMAMOTO
  • Data: 29-abr-2016


  • Resumen Espectáculo
  • O craving por alimentos pode ser definido como um desejo intenso de comer um tipo de alimento em particular. Trata-se de um comportamento bastante comum na população em geral. O presente trabalho se propôs a investigar o comportamento de craving por alimentos em população brasileira, validando questionários para este fim, além de pesquisar a relação do craving por alimentos com o estado de cromo no organismo. Como resultado, foi realizada a tradução, adaptação cultural e validação dos Food Cravings Questionnaire (State e Trait), da versão reduzida do dos Food Cravings Questionnaire-Trait e do Attitudes to Chocolate Questionnaire (ACQ), além do desenvolvimento e validação da versão brasileira do Food Craving Inventory. Foram identificadas influências do estágio de vida, sexo, adiposidade corporal e restrição dietética na ocorrência do craving por alimentos. Também foi encontrado que os indivíduos com níveis mais baixos de cromo plasmático apresentam maior craving por alimentos doces, o que foi concomitante a maior frequência de consumo deste tipo de comida e maior adiposidade corporal.

5
  • INGRID ARAÚJO DE MEDEIROS
  • Division of labor in colonies of Dinoponera quadriceps (Hymenoptera, Formicidae, Ponerinae)

  • Líder : ARRILTON ARAUJO DE SOUZA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • FIVIA DE ARAUJO LOPES
  • OMAR EDUARDO BAILEZ
  • RONARA DE SOUZA FERREIRA CHÂLINE
  • Data: 06-may-2016


  • Resumen Espectáculo
  • In social insects, the division of labor is a hallmark, being considered the key for the ecological success of them. This process raises an important question: how can ant workers, with their simple cognitive system, coordinate efficiently the tasks performed by other workers or even by different group of workers. Aiming to clarify this question, we observed the task allocation in colonies of Dinoponera quadriceps. The study was carried out in the Behavioral Biology Lab, at UFRN. In all observations and experiments, workers were individually marked with an alphanumeric tag glued in the thorax. We used instantaneous focal method to observe the colonies, registering activities of each worker every 15 minutes. In the first part of the study we investigate the effect of age on the division of labor. We observed four colonies during eight months. Each colony was observed two hours a day, three times a week. We found that young individuals perform more nest work, and also have as the main task the immature care. Thus, D. quadriceps serves a temporal polyethism flexible model. In the second part of the study, we investigated whether the workers have behavioral flexibility, being capable of responding efficiently to a disturbance. To answer this question, it was used three colonies in two different conditions: (1) foragers were removed and (2) nurse were removed. Each condition last for nine days, and colonies were observed two hours during these nine days. As a result, colonies were capable of allocating nestmates to the task that demanded more workers due to the removal, either foraging or nursing. In the third and last part of the study, we tested the effect of the workers’ weight on the task allocation. During five consecutive months four colonies were observed once a month for one hour. The next day after the observation, we removed all workers and weighted them. Our data suggest that workers that perform nest work are heavier than foragers and individuals that forage and do nest work. Our data suggest that the body weight of individuals remain engaged in activities internal to the nest is larger, they are heavier compared to those individuals that carry out these tasks and intermediate are heavier than foragers. Thus, body weight and age are modulators of task allocation in D. quadriceps, and flexibility in these colonies make them able to distribute their activities according to the demand of the colony.

6
  • NIRLEI HIRACHY COSTA BARROS
  • Strategy of sex reversal in the marbled swamp eel, Synbranchus marmoratus (Osteichthyes: Synbranchidae) a hermaphrodite, protogynous and diandric fish of Rio Grande do Norte, Brazil

  • Líder : SATHYABAMA CHELLAPPA
  • MIEMBROS DE LA BANCA :
  • GRACO AURELIO CAMARA DE MELO VIANA
  • JOSÉ ZANON DE OLIVEIRA PASSAVANTE
  • LILIANE DE LIMA GURGEL
  • NAISANDRA BEZERRA DA SILVA FARIAS
  • SATHYABAMA CHELLAPPA
  • Data: 12-jul-2016


  • Resumen Espectáculo
  • Reproductive strategy of the hermaphroditic fish, the marbled swamp eel, Synbranchus marmoratus (Bloch, 1795) (Osteichthyes: Synbranchidae) was verified, with individuals captured from July, 2011 to October, 2013, from two hydrographic basins of Rio Grande do Norte, Brazil. The following aspects of the study species were verified, morphometric measurements, taxonomy, sex ratio, length-weight relationship, body size at first sexual maturity (L50), gonadal development stages, gonadosomatic index (GSI), the condition factor (K), hepatosomatic index (HSI), fecundity and the reproductive period, besides the environmental variables and otolith analyses. The data obtained from the results of this research are presented in the form of six articles, one book chapter  and four international abstracts. The first article deals with the reproductive biology of S. marmoratus, which confirmed four different sexual types of individuals in the sampled population, and characterized the species as a protogynic hermaphrodite with diandria. The second article presents the seasonal changes of the condition factor, gonadosomatic and hepatosomatic indices of S. marmoratus during an annual period. The growth was negatively allometric and the reproductive period was during July and August, when theGSI had its peak values.The third article explains about the equilibrium strategy (K) adapted by S. marmoratus. The fourth article describes the histological aspects of gonad development during sex reversal of S. marmoratus. The fifth article presents and compares the reproductive strategies adapted by six fish species including S. marmoratus of the semi-arid region. S. marmoratus presentes equilibrium strategy with low fecundity and total spawning. The sixth article indicates that sex reversal ocourrs in females at a mean age of five and six years based on otolith studies. The book chapter is based on sex change dynamics of S. marmoratus females, showing that the transitional individuals presented both ovarian and testicular tissues in their gonads.  The four international abstracts depict the temporal dynamics of reproduction of the neotropical fish S. marmoratus, including the sex ratio, length-weight relationship, body size at first sexual maturity, K, GSI, HSI, L50 and fecundity.  S. marmoratus is a sequential hermaphroditic species, exhibiting protogyny, and diandry, presenting an equilibrium reproductive strategy. This strategy renders the species well adapted to the semi-arid region.

7
  • THIEZA GRAZIELLA ARAÚJO DA SILVA GÓES DE MELO
  • Estrous cycle and sex on acute fluoxetine interactions on the modulation of memory and anxiety- and depression-like behaviors in rats

  • Líder : REGINA HELENA DA SILVA
  • MIEMBROS DE LA BANCA :
  • ALESSANDRA MUSSI RIBEIRO
  • ELAINE CRISTINA GAVIOLI
  • FLAVIO FREITAS BARBOSA
  • REGINA HELENA DA SILVA
  • VANESSA DE PAULA SOARES RACHETTI
  • Data: 27-jul-2016


  • Resumen Espectáculo
  • Mood and anxiety disorders have great incidence among world population and present high comorbidity. Important cognitive alterations are present in both pathologies, besides the respective emotional characteristics. The main pharmacological treatment for both mood and, to some extent, anxiety disorders are the antidepressants, mainly selective serotonin reuptake inhibitors (SSRI) and serotonin-norepinephrine reuptake inhibitors (SNRI). Even though women are almost twice more affected by these disorders than men, pre-clinical research on the effects of antidepressants on this sex is not as representative as in male subjects. Further, possible influences of the natural female hormonal cycle on the action of these drugs have been poorly explored. Our study aimed to investigate the acute effects of fluoxetine on the behavior of female rats at different phases of the estrous cycle, using the plus-maze discriminative avoidance (PMDAT) and forced swimming (FS) tests. The PMDAT is held in a modified elevated plus-maze that allows concomitant evaluation of memory and anxiety. We used the exploration of the aversive enclosed arm (relative to the non-aversive enclosed arm) to evaluate acquisition, retrieval and extinction of the task in training, test and retest sessions, respectively. The exploration of the open arms was used as a measure of anxiety-like behavior. The FS was performed in two sessions (training and test) in which we evaluated the decrease in immobility duration and the increase in climbing in rats submitted to a water-filled cylinder as indicatives of an antidepressant effect. Fluoxetine (5, 10 and 20 mg/ml/kg) or vehicle were given acutely i.p. to female rats at different cycle phases, previously to the training session (PMDAT, experiments 1 and 2), after the training session (PMDAT, experiment 3) or prior to the test session (experiments 4 – PMDAT and 5 – FS). Animals were tested (PMDAT and FS) and retested (PMDAT) 24 h and 48 h after the training session, respectively. The main results obtained in PMDAT showed that: (1) neither fluoxetine administration nor cycle phase interfered with acquisition; (2) pre-training fluoxetine impaired retrieval (test session) in male, but not female rats (if all cycle phases were taken together for analysis); (3) the effects of pre-training fluoxetine in female varied according to fluoxetine dose and cycle phase: for example, no effects were detected in proestrus, and an improvement and decrease in retrieval were observed when rats were trained in estrus, depending on the dose; (4) corroborating an effect on the consolidation of the task, post-training fluoxetine induced a more ample (irrespective of cycle phase) retrieval deficit (test session); pre-test treated female rats presented retrieval deficits irrespective of phase or treatment (including vehicle), indicating an effect of the injection procedure, but we could still observe a decrease in retrieval caused by fluoxetine; (6) corroborating previous data, extinction of the task (retest session) is more expressive in males, and in females it depends on the cycle phase during training and the protocol of administration; and (7) in general, fluoxetine induced a decrease in open-arms exploration indicating an anxiogenic effect, which was more prominent at some cycle phases. Nevertheless, due to different dose ranges and cycle phases in which these alterations appeared, the drug effects on memory and anxiety do not seem to be related to each other. Regarding the results from FS, no effects of fluoxetine were detected when all phases were considered together for analysis, which is expected after an acute treatment. However, we found an increase in depressive-like behavior in animals in proestrus treated with fluoxetine. While this effect might be related with the anxiogenic effect found in the PMDAT, it is worth mentioning that females in proestrus, irrespective of treatment, present a basal alteration in this test. In conclusion, the results suggest that the acute effects of fluoxetine on memory vary according to the estrous cycle phase, as well as the memory phase in which it was administered. In addition, anxious- and depressive-like behaviors were observed in female rats, under certain conditions, after fluoxetine treatment. Despite clinical and animal studies show antidepressant and anxiolytic beneficial effects of fluoxetine prolonged treatment, the present results suggest possible cognitive and emotional acute side effects which may be influenced by sex and hormonal state.

8
  • ROSANE MARIA SIMON LAMPERT DIAS
  • Effect of wavelength and intensity of light on the circadian rhythm of motor activity in marmosets (Callithrix jacchus)

  • Líder : CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • MIEMBROS DE LA BANCA :
  • CAROLINA VIRGINIA MACEDO DE AZEVEDO
  • JOHN FONTENELE ARAUJO
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • CRHISTIANE ANDRESSA DA SILVA
  • GISELE AKEMI ODA
  • Data: 29-jul-2016


  • Resumen Espectáculo
  • Circadian entrainment depends on a complex interaction between light information and photoreceptor cells. The neurobehavioral circadian light effects are mediated primarily by retinal ganglion cells. Rods and cones operate in light detection and also interfere in the circadian timing system, but the mode of action of these photoreceptors in the control of circadian rhythms in diurnal non-human primates is unknown. Our study evaluated the effect of wavelength and intensity of light on parameters of the circadian activity rhythm in marmosets by analyzing the effect of short and long wavelengths of light in three light intensities. The locomotor activity was monitored by infrared sensors in 16 adult male marmosets, kept in controlled temperature and humidity in a light/dark (LD) cycle 12:12. The effect of two wavelengths in light phase were evaluated: short, with λmax 463 nm - in the spectral region of blue light, and long: with λmax 631 nm - in the spectral region of red light, in three light intensities: 200, 100 and 10 lux, in relation to control condition (fluorescent light). At the end of each stage, the marmosets were maintained in constant light (LL) under 10 lux and 200, to analyze the mechanisms of synchronization. An interval lasting 15 days (fluorescent light - 200 lux/2 lux) was given between the stages with different wavelengths. During the exposure to blue and red lights, the phase angle of the end of active phase was anticipated, and the duration of the active phase and the total daily activity were lower in relation to the control condition, with modulations at 10 lux. There was an increase in the spectral power of circadian period in blue and red lights in LL under 200 lux. We also observed that the duration of the experiment modifies the expression of circadian activity rhythm, possibly affecting the photoreception mechanisms in marmosets. From these results it is suggested that: 1) blue and red wavelengths of light used in LD cycles modify the endogenous expression and photic synchronization of the circadian activity rhythm in marmosets; 2) the animals respond differently to blue and red wavelengths of light at the beginning and end of active phase, with a larger advance the end of active phase, reducing the length of alpha and total daily activity, probably due to a masking effect; 3) the effect of wavelength varies depending on light intensity, with no difference between the intensities of 200 and 100 lux and a greater instability at 10 lux; 4) the duration of exposure of animals to blue and red wavelengths is a factor to be considered in the construction of experimental protocols with this species.

9
  • MELQUISEDEC ABIARE DANTAS DE SANTANA
  • Cytoarchitectonic and retinal projections characterization of the primary visual nuclei in bat (Artibeus palnirostris)

  • Líder : EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • MIEMBROS DE LA BANCA :
  • DANIEL MARQUES DE ALMEIDA PESSOA
  • EXPEDITO SILVA DO NASCIMENTO JUNIOR
  • FAUSTO PIERDONA GUZEN
  • FRANCISCO GILBERTO OLIVEIRA
  • JEFERSON DE SOUZA CAVALCANTE
  • Data: 09-sep-2016


  • Resumen Espectáculo
  • In many vertebrates, most of the brain is devoted to the processing of vision, more than any other sensory modality. This is probably due to the extremely complex task required from vision: classifying and translating the wide range of visual stimuli that animals face in the physical environment. The retina modifies and processes light trigged signals in photoreceptors which are sent to higher centers by ganglion cells. These cells axons form the optic nerves which deliver visual information to brain structures with diverse functions such as the dorsal lateral geniculate nucleus (DGL), from which the visual information rises to the cerebral cortex; the superior colliculus (SC), responsible for mediating visuomotor funtions; and the pretectal complex (CPT), involved in the pupillary light reflex and optokinetic nystagmus. In order to describe the citoarchitecture and the pattern of retinal projection in these structures in Artibeus planirostris bat, CTb intraocular injections were performed and coronal sections of the brain stained with Nissl method and sections subjected to immunohistochemistry for CTb were analyzed. Regarding to the cytoarchiteture, DGL was homogeneous and without evident lamination. However, the retinal projection revealed two layers with significantly different marking intensity, and massive contralateral input. The SC was identified as a laminar structure composed by seven layers, where retinal input was observed only on the contralateral side, targeting the superficial layers I and II. Medial pretectal nucleus, pretectal olivary nucleus, anterior pretectal nucleus, posterior pretectal nucleus and nucleus of optic tract were identified composing the CPT. Only the anterior pretectal nucleus lack retinal input, which is predominantly contralateral in all other nuclei. In sumary, the results show morphometrical and stereological features in a bat specie for the first time.

10
  • MIGUEL FERNANDES KOLODIUK
  • Studies of Squamata community and behavioral ecology of Tropidurus hispidus and Tropidurus semitaeniatus (Squamata, Tropidurudae) in lato sensu Caatinga area

  • Líder : ELIZA MARIA XAVIER FREIRE
  • MIEMBROS DE LA BANCA :
  • ELIZA MARIA XAVIER FREIRE
  • LEONARDO BARROS RIBEIRO
  • MARIA DE FATIMA ARRUDA DE MIRANDA
  • PEDRO MURILO SALES NUNES
  • RAFAEL CAMILO LAIA
  • Data: 31-oct-2016


  • Resumen Espectáculo
  • The Caatinga occupies an area of approximately 800,000 km2, and is characterized by rainfall scarcity, high temperatures, and variability in climatic seasonality, with strong intercalation of dry and floody years. Among these phytophysiognomic and morphoclimatic aspects, it is worth noting that this area has at least two landscapes known in the literature: Caatinga stricto sensu and Caatinga lato sensu. The Caatinga stricto sensu refers to areas located in the Northern Country Depression (Depressão Sertaneja Setentrional), with shrubby vegetation and higher temperatures. On the other hand, the Caatinga lato sensu comprises areas of arboreal-bushy vegetation located on the tops of plateaus and mountains with more than 500 m altitude, thus presenting milder temperatures. Classical studies highlight the existence of a pattern of relictual distribution for some lizard species of the Caatingas, which seem to be unique from areas of Caatinga lato sensu. Four 20-day trips were carried to the study area, two in 2014 and two in 2015, in March (rainy season) and September (dry season). In 2014, Squamata specimens were registered and/ or collected through active search and pitfall traps, and for each active specimen, habitat, microhabitat and activity hour were recorded. In 2015, behavioral observations of tropidurid lizards were carried out through focal sessions to analyze the themoregulatory and foraging behaviors and compare them with populations of a Caatinga stricto sensu area. A total of 34 species of Squamata was recorded, and the rarefaction curve did not reach an asymptote, indicating the possibility of more species in the area. Noteworthy is the presence of species with relictual distributions, such as Acratosaura mentalis, Enyalius bibronii and Anotosaura vanzolinia. Comparing the composition of the lizard species with other Caatinga sites, we observed the formation of three groups: communities from forested highlands; from areas of Caatinga lato sensu, and from areas of Caatinga stricto sensu. A null model analysis showed that the studied lizard community is structured on the spatial niche axis, indicating a significant influence of contemporary ecological factors on this assemblage. The non-random use of space by the lizard species indicates the presence of competitive interactions that influence the selection of habitats and microhabitats used. In general, the two Tropidurus species did not differ in their thermoregulatory behavior, although T. semitaeniatus exposed yourself to the sun more than T. hispidus during the rainy season. Regarding the foraging behavior, T. hispidus and T. semitaeniatus behaved similarly in the dry season, changing strategy during the rainy season. The two species foraged more actively during the rainy season in the studied site when compared with an area of Caatinga stricto sensu. In conclusion, the data obtained in this study confirm the presence of relictual species and the presence of different behavioral strategies for tropidurid lizards in area of Caatinga lato sensu.

11
  • STELLA GUEDES CALAZANS LIMA
  • Acustic behavior and social complexity in Cavioidea

  • Líder : RENATA SANTORO DE SOUSA LIMA
  • MIEMBROS DE LA BANCA :
  • ARRILTON ARAUJO DE SOUZA
  • CARLOS BARROS DE ARAÚJO
  • MARIA BERNARDETE CORDEIRO DE SOUSA
  • RENATA SANTORO DE SOUSA LIMA
  • ROGÉRIO GRASSETTO TEIXEIRA DA CUNHA
  • Data: 22-nov-2016


  • Resumen Espectáculo
  • The relationship between acoustic communication and sociality has been the focus of several studies concerning the hypothesis of social complexity for communication. This hypothesis predicts that animals that live in complex social groups, requires a more diverse repertoire to produce more information. However, there is a lack of studies that explain the causal directionality between social and vocal complexity in mammals, and that identify which factors -environmental and/or social - may have co-evolved and contributed to the complexity of mammalian communication. In this context, the comparative study between caviomorph species that differ in their social and ecological systems, may contribute to the understanding of this system. The caviomorph rodents are comprised of a wide diversity of species, which present variation in the size and composition of social groups, in the types of mating systems, in the types of social systems, in the types of habitat and size of acoustic repertoires. These characteristics of this taxon are available in the literature for ten species of caviomorph. In this study, we aim to provide data about the acoustic repertoire of Cuniculus Paca and Dasyprocta leporina species as well as explore the relationship between social and vocal complexity in caviomorphs. Thus, the first chapter of this work describes the vocal repertoire of spotted pacas kept in captivity. The results revealed seven types of vocalizations, mainly emitted in agonistic contexts, possibly related to territorial defense. We also found sex differences in a call that seems to function as a sexual recognition mechanism. In addition, we found an unexpected degree of vocal complexity for this solitary species. The second chapter describes the acoustic repertoire of red-rumped agoutis, consisting of 10 types of calls, mainly associated with agonistic and defense contexts during the feeding period. Sexual differences were identified in several vocalizations: “coo”, “groan”, “creak-squeak”, “grunt”, bark and snarl”, which generally have lower frequencies for males. We also found gradations, transitions and combinations of sounds that add complexity to the acoustic repertoire of red-rumped agouti, as expected for species that live in pairs or form small family groups. The third chapter tests the correlation between social and vocal complexity among ten species of caviomorphs. The results confirmed that there is a positive relationship between the complexity in the social system of the species (group composition, size of offspring, social system and mating system) and the size of caviomorph friendly vocal repertoires. On the other hand, we found no relationship among vocal complexity and ecological and morphological characteristics of the species studied here. This study corroborates with social complexity hypothesis for communication in caviomorph and contributed to identify which social and non-social factors are related to vocal complexity in these species.

2015
Disertaciones
1
  • VICTOR ANASTÁCIO DUARTE HOLANDA
  • Efeito de antagonistas do receptor NOP em camundongos expostos ao modelo do desamparo aprendido

  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ELAINE CRISTINA GAVIOLI
  • GIROLAMO CALO''
  • ROVENA CLARA GALVAO JANUARIO ENGELBERTH
  • Data: 26-feb-2015


  • Resumen Espectáculo
  • A nociceptina/orfanina FQ (N/OFQ) é um heptadecapeptídeo, sendo o ligante endógeno, de um receptor acoplado a proteína G do tipo inibitória, o receptor NOP.O sistema da nociceptina/orfanina FQ (N/OFQ) e seu receptor NOP tem se mostrado com grande potencial para o desenvolvimento de fármacos antidepressivos com evidências farmacológicas e genéticas apontando um potencial efeito antidepressivo induzido pelo bloqueio do receptor NOP. O modelo do desamparo aprendido (DA) emprega eletrochoques, incontroláveis e imprevisíveis, nas patas dos animais como evento estressor para induzir um fenótipo tipo depressivo. Este paradigma é baseado no fato de que após exposição à eletrochoques incontroláveis, os animais desenvolvem déficits no comportamento de escape do compartimento eletrificado, evento este revertido pelo uso de antidepressivos. O DA é um modelo de depressão mais bem validado em comparação com os testes de desespero comportamental, que são atualmente mais utilizados no screening de novos agentes antidepressivos. Sendo assim, o presente estudo tem como objetivo validar o modelo do desamparo aprendido nas nossas condições experimentais, bem como avaliar a ação de antagonistas do receptor NOP em animais que desenvolveram a condição de desamparo. Para realização deste estudo, camundongos machos foram submetidos a três fases do protocolo DA (i.e., (1) indução,  (2) screening e (3) teste). Os animais que desenvolveram o fenótipo tipo depressivo foram submetidos à sessão teste, cuja fase existe a possibilidade de escape do eletrochoque e o tempo de escape do compartimento onde recebeu o choque, bem como o número de vezes que o animal não escapou deste compartimento foi registrado. O efeito dos seguintes tratamentos, administrados antes da sessão de teste, foi avaliado: nortriptilina (30 mg/Kg, ip, 60 min),fluoxetina (30 mg/Kg, ip, 60 min), ambos antidepressivos clássicos, SB-612111 (1 e 10 mg/Kg, ip, 30 min) e UFP-101 (1 e 10 nmol, icv, 5 min), ambos antagonistas NOP. Ainda, para descartar possíveis falsos positivos no comportamento do tipo desamparado, foi avaliado o efeito destas drogas sobre os componentes motivacional e cognitivo. Assim, foi evidenciado que nos animais que desenvolverem o fenótipo tipo depressivo nortriptilina, SB-612111 e UFP-101 foram eficazes em reduzir a latência de escape e o número de vezes que o animal não escapou do compartimento eletrificado, sem promover nenhuma alteração nos componentes motivacional e cognitivo do DA; o mesmo não ocorre com a administração de fluoxetina, que não promove nenhuma alteração nos parâmetros analisados. Em conclusão, o tratamento agudo com antagonistas NOP é capaz de promover um efeito do tipo antidepressivo em camundongos submetidos ao modelo do desamparo aprendido.

2
  • LISIANE DE SANTANA SOUZA
  • PADRONIZAÇÃO DE TESTES PARA AVALIAÇÃO DO ESTADO DE MANIA E POTENCIAL ANTI-MANÍACO DE UM AGONISTA DO RECEPTOR NOP

  • Líder : ELAINE CRISTINA GAVIOLI
  • MIEMBROS DE LA BANCA :
  • ALIANDA MAIRA CORNELIO DA SILVA
  • ELAINE CRISTINA GAVIOLI
  • PABLO PANDOLFO
  • Data: 13-mar-2015