Banca de DEFESA: LUANA BARBOSA DA CRUZ

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : LUANA BARBOSA DA CRUZ
DATE: 20/06/2023
TIME: 08:30
LOCAL: meet.google.com/fnu-pjar-jqq
TITLE:

Tape casting of hydroxyapatite and tricalcium phosphate membranes with added manganese for bone regeneration

KEY WORDS:

Tape Casting, biomaterials, manganese, TCP, hydroxyapatite.

PAGES: 118
BIG AREA: Engenharias
AREA: Engenharia de Materiais e Metalúrgica
SUBÁREA: Materiais Não-Metálicos
SPECIALTY: Cerâmicos
SUMMARY:

In recent years, damage to bone tissue has been increasing, especially in the elderly population, thus reducing the condition of well-being. The lesions represent an enormous challenge for the repair of the affected regions due to the slow healing rates (especially among the older), the high cost of treatment and the high risk of rejection by the body. Alternative techniques have been increasingly studied to promote improved bone regeneration; among them, one of the most promising is the use of biomaterials based on the application of barrier membranes for guided bone regeneration. They are able to promote tissue integration, since they prevent the invasion of fibroblasts by providing stability to bone grafts and guarantee protection for the osteogenesis process, thus accelerating the healing process and restoration of the affected area. The development of calcium phosphate membranes has been increasingly researched due to their chemical and biological similarity to bone constitution, for their good cell adhesion and relatively low cost as well. In this work, studies were carried out regarding the development of ceramic membranes of tricalcium phosphate and hydroxyapatite through the Tape Casting method with and without the addition of manganese to improve guided bone regeneration. The ceramic suspension was the first part characterized, being carried out through the study of the rheological behavior. Subsequently, the membrane was characterized through X-ray diffraction (XRD), thermal analysis (TGA/DTA), scanning electron microscopy (SEM-FEG), Raman, degree of swelling, bioactivity and cytotoxicity. The results obtained showed a suspension of pseudoplastic behavior suitable for the process via Tape Casting, for the membranes were flexible, with characteristic phases, biodegradable, biocompatible, non-toxic and with good water absorption, which makes it ideal for the desired application.

 

COMMITTEE MEMBERS:
Presidente - 1149564 - WILSON ACCHAR
Externo à Instituição - EDUARDO GALVAO RAMALHO
Externo à Instituição - HUGO PLÍNIO DE ANDRADE ALVES - IFPB
Externa à Instituição - SHEYLA KAROLINA JUSTINO MARQUES - IFAl
Externo à Instituição - VAMBERTO MONTEIRO DA SILVA - IFPB