Banca de DEFESA: ERICA ROBERTA BARBALHO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : ERICA ROBERTA BARBALHO
DATA : 27/02/2019
HORA: 14:30
LOCAL: Sala de Reuniões do Departamento de Saúde Coletiva
TÍTULO:

MUSCLE MASS AND ITS INPLICATION IN THE PHYSICAL FUNCTION IN OLDER ADULTS GASTROINTESTINAL CANCER PATIENTS

PALAVRAS-CHAVES:

Sarcopenia, muscle quality, skeletal muscles, handgrip, gait speed

PÁGINAS: 55
GRANDE ÁREA: Ciências da Saúde
ÁREA: Educação Física
RESUMO:

Sarcopenia, a disease that associates skeletal muscle loss with impairment of physical function, is highly prevalent in aging and associated with adverse outcomes in the elderly with cancer. However, studies with oncology patients only analyze the amount of muscle mass, and lack collaborative information on muscle quality and physical function associated with this diagnosis. Therefore, the aim of the present study was to explore the associations between muscle mass, divided into four phenotypes according to the quantity and quality of muscle, and physical function in the elderly with cancer of the gastrointestinal tract. A cross-sectional study was performed evaluating the physical function through the manual grip force (dynamometry) and the gait speed test. To evaluate muscle mass, computed tomography images of the abdominal region were analyzed with specific software, using the parameters of skeletal muscle index (IME) and muscular quality (muscular attenuation). The individuals were classified into four musculature phenotypes: quantity and normal quality, low quantity only, low quality only and low quantity and muscular quality. To compare the physical function variables among the four different phenotypes, we used one-way analysis of variance and to test the associations between muscle mass and physical function, the simple linear regression models were used. A significance level of 5% was adopted. We evaluated 167 patients, with a higher prevalence of males (58.1%) and mean age of 69.17 ± 7.97 years. The majority of patients were physically inactive (82.6%), and the prevalence of sarcopenia was 37.7%. The elderly male oncology with low quality and / or muscular quantity phenotypes presented worse performance in dynamometry and gait tests. There were associations between physical function and quantity and muscular quality, and in the regression analysis, these joints better explained the strength and performance tests in males. We conclude that there are associations between muscle mass and physical function, especially in the male sex, being impaired by the muscular phenotypes with low quantity and / or quality in elderly patients with neoplasias of the gastrointestinal tract.

MEMBROS DA BANCA:
Interna - 1879430 - ANA PAULA TRUSSARDI FAYH
Interno - 2682821 - EDUARDO CALDAS COSTA
Interno - 1989744 - HASSAN MOHAMED ELSANGEDY
Externa à Instituição - FLÁVIA MORAES SILVA
Externa à Instituição - JULIANA FLORINDA DE MENDONCA REGO