Complications of prematurity in newborns' motor, cognitive and language development: a systematic review with meta- analysis.
Newborn Diseases; Prematurity; Child development; Complications.
Newborns are considered premature when their birth occurs before completing 37 weeks of gestation and, consequently, the lower the gestational age, the greater the risk of adverse biological conditions and consequent abnormalities of the non-neurodevelopment of pregnancy. Prematurity is a risk factor for child development, as it interrupts brain maturation processes, which can lead to behavioral, cognitive and functional deficiencies, recognized as delays in child neuropsychomotor development. The increase in the number of premature births, after the need for two researchers and child health professionals to develop intervention strategies at an outpatient and hospital level to ensure the survival of the newborn and mitigate the consequences that can arise from brain immaturity. Objective: To verify the results on the complications of prematurity in the cognitive, motor and language development of newborns. Method: This is a systematic review with meta- analysis. The method design will be developed based on the guidelines defined by the Cochrane Handbook (2011) and the instrument The PRISMA Statement (PRISMA). For the construction of the guiding question, the PICO strategy (Patient or Problem, Intervention, Control or Comparasion, Outcomes) will be used: What are the complications of prematurity in the cognitive, motor and language development of newborns? A search will be carried out in the electronic data sources National Library of Medicine, Web of Science, Cumulative Index to Nursing and Allied Health Literature, SciVerse Scopus, Cochrane Library and Gale Academic OneFile, in addition to CAPES theses and dissertation directories for access to the literature. gray The search will use MeSH indexed descriptors: Infant, Newborn, Diseases; Infant, Premature; Child Development; Complication. Primary quantitative studies will be included, such as quasi-experimental and randomized clinical trials that assess the complications of prematurity in the motor, cognitive and language development of newborns. The research will be carried out without language restrictions and without time frame. Review articles, meta-analyses, abstracts, conference proceedings, editorials/letters, case reports and studies carried out with secondary data will be excluded.For the selection of studies, a prior evaluation of the titles and abstracts will be carried out in an initial search which will be carried out by two researchers, independently and blinded, strictly corresponding to the inclusion and exclusion criteria and other aspects previously defined in the protocol. of research. The data will be organized in an electronic spreadsheet, built in Microsoft Office Excel and analyzed using descriptive statistics using the SPSS statistical package version 21.0 for Windows. The Kappa coefficient of agreement will be applied to verify the agreement between the two researchers for their respective ordinal assessments of the same sample.