Banca de QUALIFICAÇÃO: TÁSSYO LEANDRO DA SILVA
Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : TÁSSYO LEANDRO DA SILVA
DATE: 22/03/2023
TIME: 09:00
LOCAL: Link de acesso para videoconferência: https://meet.google.com/yxz-ugvj-jur
TITLE:
Applicability and antioxidant activity of Prosopis juliflora extract as a multifunctional cosmetic raw material
KEY WORDS:
Mesquite; Prosopis juliflora; Antioxidant; Cosmetics; Melanogenesis.
PAGES: 98
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUMMARY:
The rich biodiversity of plant species in Brazil encourages studies with plants for the
development of products containing natural compounds. P. juliflora, popularly known
as algaroba, is a plant that was brought from Peru, introduced and spread through the
semi-arid region of the Northeast and, becoming an invasive species in the Caatinga.
Studies report antimicrobial, antioxidant, antimalarial, antitumor actions, among others,
due to the presence of secondary metabolites such as alkaloids, terpenoids, tannins
and flavonoids, present in different parts of this plant. Some of these metabolites can
be used by the cosmetic industry with different activities. This work aims to evaluate
the antioxidative and antityrosinase activity of the P. juliflora fruit extract and to develop
cosmetic formulations for harmonizing skin color. For that, the extract obtained by
previously standardized methodologies was evaluated for the concentration of total
flavonoids, which showed concentrations of 1.71 ± 0.26 µg EQ/mg and 0.21 ± 0.01 mg
GAE/g of phenolic compounds. In addition, the extract was obtained by previously
standardized methodologies and the antioxidant activity in vitro was evaluated by
different methodologies: scavenging of superoxide radicals and 2,2-diphenyl-1-
picrylhydrazyl (DPPH), total antioxidant capacity, reducing power, chelation of metal
ions (Cu2+ and Fe2+) and superoxide anion radicals (O2-), and the antioxidant activity
of the lyophilized extract was observed. The in vitro safety of the extract was performed
through cytotoxicity tests and the samples did not show cytotoxic effects. The samples
have not yet shown to have an antimelanogenic action, but new tests are needed to
elucidate this activity. This project, in addition to contributing scientifically by
demonstrating the use of a Caatinga plant in anti-melanogenic cosmetic products, will
also contribute to adding value to the P. juliflora production chain, aiming to enhance
aspects of environmental and social responsibility and Brazilian biodiversity.
COMMITTEE MEMBERS:
Externa à Instituição - CASSIARA CAMELO ELOI DE SOUZA - UFBA
Externo à Instituição - ANDRE LEANDRO SILVA - UFOB
Presidente - 3652554 - FRANCISCO CANINDE DE SOUSA JUNIOR