Banca de QUALIFICAÇÃO: LORENA MARIA LIMA DE ARAÚJO

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : LORENA MARIA LIMA DE ARAÚJO
DATE: 18/03/2020
TIME: 14:00
LOCAL: SALA 2 DO PPGCF
TITLE:

Acquisition of proton pump inhibitor (PPI) in community pharmacies: characterization and factors associated with prolonged use.

KEY WORDS:

Proton pump inhibitors, drug use study, community pharmacy.

PAGES: 58
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUMMARY:

Proton pump inhibitors (PPIs) are among the most prescribed drugs in the world. However, information on user profiles and factors associated with their purchase at community pharmacies is scarce. The aim of this study is to characterize the pattern of PPI use and factors associated with inappropriate use and prolonged use. A cross-sectional, prospective and observational study involving interviews with 600 patients purchasing PPIs for their own use in community pharmacies is being conducted. The socio-demographic and clinical profile (diseases and other medications) is being investigated. Regarding PPIs and their use, the indication for use, dosage adopted, time and patient knowledge about the drug, potential drug interactions and pharmacoeconomic aspects are being evaluated. We are using descriptive statistics for sample characterization and multivariate logistic regression model to determine factors associated with PPI use. Preliminary results point to an adequate use of PPI regarding indication and form of use (77%), however there is a high prevalence of prolonged use of these drugs (30%) associated with lack of knowledge about adverse reactions (56%). About 18% of users have potential PPI-related drug interactions (PDI), especially older individuals (OR 1.05; 95% CI) and women (OR 2.27; 95% CI). The selection of the PPI does not consider the purchasing power of the patient, with lower HDI neighborhoods presenting the cost of PPI treatment similar to the most economically developed locations in the city. Therefore, PPI use is adequate as to indication and form of use, however, it is used for prolonged periods without knowledge of the risks and existing PDIs, as well as a discrepancy in the prescription between patient's purchasing power and cost of treatment.

BANKING MEMBERS:
Externa ao Programa - 2492944 - CAROLINE ADDISON CARVALHO XAVIER DE MEDEIROS
Externa à Instituição - ERICA LIRA DA SILVA FREITAS - UFRN
Presidente - 1893445 - EUZEBIO GUIMARAES BARBOSA