PREVALÊNCIA DE INFERTILIDADE CAUSADA PELA SÍNDROME DOS OVÁRIOS POLICÍSTICOS E SUAS CONSEQUÊNCIAS PSÍQUICAS
Polycystic ovarian syndrome; infertility; mental consequences
Polycystic Ovarian Syndrome (PCOS) is a gynecological endocrinopathy that affects about 5 to 20% of women of childbearing age. In addition to reproductive complications, this syndrome is associated with metabolic changes and psychological disorders, such as reduced quality of life and increased risk factors for anxiety and depression, which can degrade health and well-being over time. Infertility can cause negative impacts that involve emotional, physical, psychological and social suffering. Because it is considered one of the main causes of female infertility, the present study aimed to estimate the prevalence of infertility caused by PCOS and its psychic consequences. The study population consisted of women with fertile and infertile PCOS (n = 75), evaluated for clinical, biochemical and psychological aspects. The WHOQOL-BREF, BDI and SCL-90-R were collected from biological material and from clinical and sociodemographic questionnaires. The analysis of the information collected was performed using a statistical system based on Stata version 11 Univariate analysis was performed by logistic regression to determine which of the clinical variables considered in this study were associated with infertility, and the respective odds ratios and 95% confidence intervals were calculated. The variables that presented p value <0.15 in the univariate analysis were included in a multivariate logistic regression model, being considered significant, associations with p value <0.05. Infertility was observed in 43 (57.3%) women as well as the presence of depressive symptoms, with no evidence of association with infertility as an isolated factor in PCOS, increasing the probability of potentiating depression, reducing quality of life and suffering. However, in the multivariate analysis, it was identified that infertility was independently associated with age (odds ratio: 1.16, 95% CI: 1.03-1.31, p = 0.02), parity (odds ratio : 0.15, 95% CI: 0.04-0.53, p = 0.00) and abortion (odds ratio: 21.47, 95% CI: 1.54-298.11, p = 0.02 ). From the evaluation and management of the psychological aspects involved in PCOS, it will be possible to improve the understanding of its etiology and treatment according to the degree of need in each case.