Banca de QUALIFICAÇÃO: CAMILA TATYANNE SANTOS DE FREITAS

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
DISCENTE : CAMILA TATYANNE SANTOS DE FREITAS
DATA : 26/09/2018
HORA: 09:00
LOCAL: PROGRAMA DE PÓS-GRADUAÇÃO EM PATOLOGIA ORAL
TÍTULO:

IMMUNOISTOKYMIC STUDY OF VEGF AND α-SMA PROTEINS IN RADICULAR AND RESIDUAL CYSTS

PALAVRAS-CHAVES:

myofibroblasts, angiogenesis and inflammatory odontogenic cysts.

PÁGINAS: 41
GRANDE ÁREA: Ciências da Saúde
ÁREA: Odontologia
SUBÁREA: Clínica Odontológica
RESUMO:

Myofibroblasts are cells that express alpha smooth muscle actin (α-SMA) and play an important role in physiological and pathological conditions, as well as in organogenesis, repair, regeneration, inflammation and tumorigenesis. Studies involving inflammatory odontogenic lesions reveal that myofibroblasts are related to growth and progression by elasticity restrict in the wall of cysts so controlling their expansion. Other important element in the pathogenesis of inflammatory cysts is vascular endothelial growth factor (VEGF) which induces proliferation, differentiation and migration of vascular endothelial cells. In addition, VEGF can instigates extravasation of plasma proteins, accumulates fluid and produces edema, promoting the expansion of cystic lesions. Thus, the present work proposes to evaluate immunohistochemical expression of VEGF and α-SMA in radicular cysts (RC) and residual radicular cysts (RRCs), aiming a better understanding of these periapicopathies’ etiopathogenesis. Thus, 30 RCs and 30 RRCs were selected for immunohistochemical analysis under mentioned biomarkers.

MEMBROS DA BANCA:
Interno - 1258707 - ANTONIO DE LISBOA LOPES COSTA
Interno - 350485 - HEBEL CAVALCANTI GALVAO
Interno - 350484 - ROSEANA DE ALMEIDA FREITAS