Banca de QUALIFICAÇÃO: MARCELO ANDERSON BARBOSA NASCIMENTO

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
DISCENTE : MARCELO ANDERSON BARBOSA NASCIMENTO
DATA : 31/10/2017
HORA: 08:30
LOCAL: AUDITÓRIO DO DEPARTAMENTO DE ODONTOLOGIAUFRN
TÍTULO:

IMMUNOHISTOCHEMICAL STUDY OF SOX2 TRANSCRIPTION FACTOR AND FGF-10 AND WNT-1 REGULATORS IN BENIGN EPITHELIUM ODONTOGENIC LESIONS

PALAVRAS-CHAVES:

Stem cells, Odontogenic Epithelial Lesions; Immunohistochemistry; SOX2; FGF10; Wnt-1.

PÁGINAS: 27
GRANDE ÁREA: Ciências da Saúde
ÁREA: Odontologia
SUBÁREA: Clínica Odontológica
RESUMO:

The odontogenic lesions constitute a heterogeneous group of pathologies that affect the jaws, originating from the epithelial or mesenchymal remnants of dental embryogenesis. These lesions may range from cysts to true neoplasms, which sometimes exhibit diverse clinical manifestations. Odontogenic cysts are relatively common and have a slow and benign course. However, some cysts can reach a significant size and if not properly diagnosed and treated, they result in significant disorders for patients. Neoplasms derived from epithelial, ectomesenchymal or mesenchymal tissues that give rise to the teeth are called odontogenic tumors. Some of these lesions have a similar evolution to hamartomas and others may have malignant behavior. Regulation of stem cells is critical for homeostasis and tissue function and disorders in their regulation can lead to excessive proliferation of cells and many tumors are originated and / or maintained by tumor stem cells. Stem cell markers are expressed in many tumor cells and are involved in various stages of tumor formation. In odontogenic tumors, the formation of dental tissues is continuous and is believed to derive from cells associated with tooth development. The contribution of dental stem cells to the generation of odontogenic tumors is not yet well known. In this sense, it is justified to carry out researches that evaluate the role of these cells in the development of odontogenic cysts and tumors, considering that these originate from alterations that may occur during odontogenesis.

MEMBROS DA BANCA:
Interno - 2220417 - CARLOS AUGUSTO GALVAO BARBOZA
Presidente - 346077 - LELIA BATISTA DE SOUZA
Interno - 2859541 - PEDRO PAULO DE ANDRADE SANTOS