FUNCTIONAL NEAR INFRARED SPECTROSCOPY (fNIRS) IN INFANTS WITH CONGENITAL SYPHILIS
Near-infrared spectroscopy; fNIRS (functional near infrared spectroscopy); Spectroscopy; Newborn infants; Speech Perception; Auditory Perception
Introduction: Congenital syphilis (CS) is caused by the bacterium Treponema pallidum, which can affect the vestibulocochlear nerve. However, there is little information about consequences on cerebral hemodynamics. Objective: To study the parameters of functional near infrared spectroscopy (fNIRS) with speech stimulus in infants to support a protocol to be applied in infants with CS. Method: Two studies will be carried out. Study 1 will be a systematic review of fNIRS parameters (Prospero n. CRD42022311267). The search was performed in PubMed, Embase, Scopus, Web of Science, LILACS, PsycINFO, Livivo, Google Scholar and ProQuest. Cross-sectional studies in infants aged 0 to 24 months and normal hearing were included. Study 2 is a cross-sectional and prospective study (CEP/HUOL n. 5,323,957). The sample will be infants with CS and another group without risk indicators. Initially, a pilot study was carried out with normal hearing adults using the NIRSport equipment with /da/ and /ba/ syllables. Partial results: 1.227 articles were identified. At the end of phase 1, there were 113 for complete reading, remaining 75 for final analysis. In study 2, the elaboration of auditory stimuli was carried out, the design of the experiment, capturing the records and analyzes of 28 adults. This pilot gave support to redefine the type of stimulus presentation, the amount of stimuli within a block, the duration of stimulus time and the number of repetitions of the blocks. Partial considerations: It is expected to identify the most common parameters used in fNIRS in babies, as well as to verify the influence of SC on cerebral hemodynamics.