Banca de QUALIFICAÇÃO: LUCIANA MOREIRA DANTAS BARRETO

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : LUCIANA MOREIRA DANTAS BARRETO
DATE: 02/08/2021
TIME: 14:30
LOCAL: Em ambiente virtual (Google Meet)
TITLE:

QUALITY IN THE MANIPULATION OF ANTINEOPLASTIC THERAPY IN A UNIVERSITY HOSPITAL: APPLICATION OF AN IMPROVEMENT CYCLE

KEY WORDS:

Antineoplastic, Patient Safety, Good Manipulation Practices, Quality Management.

PAGES: 30
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUBÁREA: Saúde Pública
SUMMARY:

Introduction: Improving safety in the use of high-surveillance drugs is one of the international patient safety goals established by the World Health Organization. Antineoplastic drugs are part of the AVM list and for this reason have high potential to cause adverse events. The complexity of antineoplastic therapy contributes to the high error rate and marked severity. The present study will focus on the process d and manipulation of ED.

Objective: To evaluate and improve the quality in the process of handling ED in a university hospital in Rio Grande do Norte.

Methodology: This is the implementation of an internal improvement cycle, using a pre-after-after-type almost-experimental design, with quantitative approach, to be developed at the Central de Misturas Intravenosas/Setor de Farmácia Hospitalar do Hospital Universitário Onofre Lopes – Natal/RN. The improvement cycle will be developed in six methodological stages. As a fulfillment of the practical work,   developed in the master's degree, it was possible to perform activities that fit some of the stages of the improvement cycle related to the research object: 1) Identification and prioritization of the quality problem - opportunity for improvement  selected was  "Improvement in the safety of the manipulation of antineoplastic therapy"; 2) Analysis of the causes of the problem - a cause and effect diagram was elaborated; 3) Elaboration of quality assessment criteria: 5 quality criteria related to the manipulation process were elaborated (1. Medical prescription should be evaluated by the pharmacist, 2.TA must be correctly identified, 3.Equipo should be properly filled with serum,   4.Os inputs should be separated by patient before transferring them to the handling area and  5. Manipulated TA must be visually inspected); 4) Initial evaluation of the conformity of the criteria: 60 manipulated injectable AT were evaluated, randomly selected simply, prescribed for the treatment of cancer patients treated at HUOL; 5) Improvement intervention directed to the most problematic criteria: After the 1st evaluation, it was verified that criteria 3, 4 and 1 were the most problematic, the set of interventions suggested by the team was: Reorganization of work processes, team training   and Material acquisition; 6)  Two evaluationsofthe quality level to verify the effectiveness of the implemented intervention: This stage will still be performed after the implementation of the interventions. To calculate the improvement between the evaluations, the calculation of the point estimate will be performed, with a confidence interval (95%) the level of compliance with the criteria of the selected samples, calculating the values of absolute and relative improvements of each of the criteria, and for the statistical significance of the detected improvement will be performed a unilateral hypothesis test by calculating the Z value, considering as null hypothesis the absence of improvement, not considering    when p≤0,05. The results will be presented by pareto charts before-after, as it is a complete and informative graphic representation that facilitates the prioritization of intervention strategies.

BANKING MEMBERS:
Presidente - 3578073 - RODRIGO ASSIS NEVES DANTAS
Interno - 1868020 - ZENEWTON ANDRÉ DA SILVA GAMA
Externo ao Programa - 1674779 - NEY MOURA LEMOS PEREIRA