Banca de QUALIFICAÇÃO: DEYZIANE FERNANDES DA SILVA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : DEYZIANE FERNANDES DA SILVA
DATE: 22/04/2025
TIME: 14:00
LOCAL: Departamento de Enfermagem
TITLE:

USE OF STINGLESS BEE HONEY (MELIPONINAE SUBFAMILY) IN WOUND TREATMENT: A SYSTEMATIC REVIEW AND PROTOTYPE DEVELOPMENT  

 

KEY WORDS:

Honey; Stingless bee; Wound healing.

PAGES: 17
BIG AREA: Ciências da Saúde
AREA: Enfermagem
SUMMARY:

INTRODUCTION: The increasing microbial resistance to conventional antibiotics has
motivated the search for effective and safe therapeutic alternatives for the treatment of
wounds. Stingless bee honey (Meliponinae) appears to be a promising option due to its
antimicrobial, anti-inflammatory and healing properties, with the potential to accelerate tissue
regeneration, modulate the inflammatory response and reduce infections, especially in
chronic and difficult-to-heal wounds. OBJECTIVES: This project aims to evaluate the
efficacy of stingless bee honey in wound healing, comparing the healing rate between
wounds treated with honey and conventional methods, evaluating the inflammatory response
and tissue regeneration in the different groups, and analyzing possible adverse effects or
limitations of the topical use of honey. In addition, we intend to develop a honey-based
prototype for use as a primary dressing on wounds. METHODOLOGY: The research will be
developed in two phases. The first phase will consist of a systematic review and meta-
analysis of preclinical studies on the efficacy of stingless bee honey in wound healing,
considering animal and in vitro models. The second phase will be dedicated to the
development and analysis of a honey-based prototype, evaluating its composition, stability,
safety and efficacy in vitro and, possibly, in vivo. EXPECTED RESULTS: The systematic
review is expected to provide robust evidence on the efficacy of stingless bee honey in
wound healing, identifying the best methods of application. The development of the
prototype may result in a safe and effective product for clinical use, contributing to the
valorization of natural products, the reduction of the indiscriminate use of antibiotics and the
expansion of therapeutic options for the treatment of wounds.

 

COMMITTEE MEMBERS:
Interna - 2882013 - ISABELLE KATHERINNE FERNANDES COSTA
Externo à Instituição - KLEYTON SANTOS DE MEDEIROS
Presidente - 1220986 - RHAYSSA DE OLIVEIRA E ARAUJO