Banca de QUALIFICAÇÃO: FERNANDA DE CASTRO TEIXEIRA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : FERNANDA DE CASTRO TEIXEIRA
DATE: 18/10/2024
TIME: 09:30
LOCAL: Google Meet
TITLE:

EFFICACY OF IRON SUPPLEMENTATION IN ANEMIC PATIENTS IN THE PREOPERATIVE SURGERY PERIOD: SYSTEMATIC REVIEW AND META-ANALYSIS.

KEY WORDS:

Iron Deficiency, Cardiac Surgery, Extracorporeal Circulation and Perioperative Period.

 

PAGES: 30
BIG AREA: Ciências da Saúde
AREA: Enfermagem
SUMMARY:

Iron or micronutrient deficiency (ID) is a condition that affects approximately 40% to 50% of all patients with chronic heart failure and up to 80% with acute heart failure. Iron deficiency is defined as insufficient levels to meet the physiological demands of the body, significantly impairing the quality of life. Consequently, it has been observed that recognizing and treating ID becomes advantageous for patients with heart disease. Patients with iron deficiency are associated with greater blood transfusions in the perioperative period and,
consequently, are subject to possible transfusion reactions, increased postoperative morbidity and mortality, transmission of infection, risk of immunosuppression and increased hospital costs. Thus, the use of blood
products is related to an independent risk factor for postoperative infection. Therefore, the study has the general objective of evaluating the effectiveness of iron supplementation in anemic patients in the preoperative period of cardiac surgery. This is a systematic review and meta-analysis to be conducted in
accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Network Meta-Analyses (PRISMA-NMA) and registered in the International prospective register of systematic reviews (PROSPERO) database, identification number CRD42024568295. Using the “PICOS” strategy (Population, Intervention, Comparison, Outcome and Type of Study), the following research question was constructed: “Does the use of different modalities of iron therapy (intravenous or oral iron) reduce the need for blood transfusion, mortality and length of hospital stay in adult patients with anemia undergoing cardiac surgery?” The search will be performed by two researchers simultaneously in the following databases: Catalog of Theses and Dissertations (CAPES), Cochrane Library, Google Scholar, Latin American and Caribbean Literature on Health Sciences (LILACS), National Library of Medicine and National Institutes of Health (PUBMED), Scientific Electronic Library Online (SCIELO), Science Direct, Elsevier's Scopus (SCOPUS), Web of Science and
Wiley Online Library. The following Health Sciences Descriptors/Medical Subject Headings will be used: cardiac surgery, cardiopulmonary bypass, anemia, ferrous sulfate, perioperative period, iron deficiency. All Cochrane
Systematic Reviews (CSRs) and non-Cochrane Systematic Reviews (non- CSRs) with or without meta-analysis that described the population aged 18 years or older using oral or intravenous iron supplementation in anemic patients in the preoperative period of cardiac surgery will be included in the study. There will be no time restrictions for the selection of studies or the language of the publications; duplicate texts in the databases will be excluded. The results will be extracted using a standardized form containing information about the
authors, year of publication, study location, type of study, main objectives, population, age, sex, type of iron supplementation route, hematocrit and hemoglobin values in the preoperative and postoperative periods, quantity of blood products used, postoperative complications, mortality analysis and length of hospital stay. The meta-analysis will be performed using the R software, considering 95% confidence intervals. The risk of bias analysis will be performed using the Assessment of Multiple Systematic Reviews (AMSTAR 2) and the quality of evidence will be assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE).

COMMITTEE MEMBERS:
Interna - 2553720 - KATIA REGINA BARROS RIBEIRO
Externo à Instituição - KLEYTON SANTOS DE MEDEIROS
Presidente - 3578073 - RODRIGO ASSIS NEVES DANTAS