Banca de QUALIFICAÇÃO: NEYNA SANTOS MORAIS

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : NEYNA SANTOS MORAIS
DATE: 07/12/2025
TIME: 08:30
LOCAL: Google Meet (solicitar link à secretaria do programa)
TITLE:

EVALUATION OF BIOLOGICAL ACTIVITIES AND TOXICITY OF BURITI OIL NANOPARTICLES (Mauritia Flexuosa L.f).

 

KEY WORDS:

Buriti oil; nanoencapsulation; porcine gelatin; antioxidant activity; Candida spp.; C. elegans; in vitro cytotoxicity; simulated digestion.

PAGES: 72
BIG AREA: Ciências Biológicas
AREA: Bioquímica
SUMMARY:

The oil extracted from buriti (Mauritia flexuosa) contains a significant amount of bioactive compounds, but its sensitivity to environmental factors and industrial processes poses a challenge to the industry. The objective of this study was to analyze the biological activities, simulated digestion, and safety of nanoencapsulated buriti oil. The nanoscale particles were spherical, had a mean size of 69.72 ± 15.20 nm, a high encapsulation index (95.79%), and were highly water-soluble. Simulated digestion resulted in a gradual release of fatty acids in the gastric and intestinal stages, maintaining the polyunsaturated fatty acids. The nanoparticle exhibited greater antioxidant potency (23.40 mgAA/g) compared to free buriti oil and exhibited antifungal activity against Candida albicans, C. tropicalis, and C. krusei. Acute toxicity tests with C. elegans showed no reduction in egg hatching or increased nematode growth. The data indicate that nanoencapsulation of buriti oil safely enhances its benefits and suggests future applications in supplied products. 

COMMITTEE MEMBERS:
Externa ao Programa - 3211846 - KARLA SUZANNE FLORENTINO DA SILVA CHAVES DAMASCENO - nullPresidente - 1517220 - MARCIA REGINA DA SILVA PEDRINI
Externo ao Programa - 3471264 - WÓGENES NUNES DE OLIVEIRA - null