Banca de QUALIFICAÇÃO: FLAVIO PEREIRA DOS SANTOS FILHO

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : FLAVIO PEREIRA DOS SANTOS FILHO
DATE: 25/05/2026
TIME: 15:00
LOCAL: Departamento de Odontologia
TITLE:

Evaluation of desensitizing toothpastes with obliterating and neural action in reducing tooth sensitivity during at-home whitening with hydrogen peroxide

KEY WORDS:

Toothpastes; Sensitivity; Teeth whitening

PAGES: 26
BIG AREA: Ciências da Saúde
AREA: Odontologia
SUMMARY:

At-home supervised tooth whitening is widely used in dental practice due to its conservative nature and good aesthetic results. However, tooth sensitivity represents the main adverse effect associated with the treatment, potentially compromising patients' comfort and quality of life. Recent evidence suggests that this sensitivity occurs not only due to the movement of dentinal fluids but also due to neuroinflammatory mechanisms related to the action of hydrogen peroxide on the dental pulp. In this context, different desensitizing toothpastes have been indicated to minimize this discomfort, particularly those with obliterating action on dentinal tubules and those with neural action. This study aims to evaluate the efficacy of desensitizing toothpastes with obliterating and neural action in reducing tooth sensitivity during at-home supervised whitening with hydrogen peroxide at concentrations of 7.5% and 10%. This is a randomized, triple-blind clinical trial to be conducted at the Department of Dentistry of the Federal University of Rio Grande do Norte (UFRN). Initially, a pilot study will be conducted with 60 participants, distributed into six experimental groups according to the concentration of the whitening gel and the type of toothpaste used: toothpaste without desensitizing action, toothpaste with obliterating action, and toothpaste with neural action. Participants will undergo supervised at-home whitening for 14 days, using individualized trays made by the research team. The variables analyzed will include tooth sensitivity, color change, impact on quality of life, and gingival bleeding index. Sensitivity will be assessed using the VAS and ENA scales; tooth color will be measured using the Vita scale and a VITA Easyshade digital spectrophotometer; quality of life will be analyzed using the adapted OHIP-14 questionnaire; and the gingival bleeding index will be used to monitor periodontal condition. The data obtained will be submitted to statistical analysis with a significance level of 5% and a test power of 80%. It is expected that the results will contribute to the definition of safer and more comfortable clinical protocols during at-home teeth whitening, assisting dentists in choosing more effective desensitizing toothpastes to reduce tooth sensitivity and improve patients' quality of life.

COMMITTEE MEMBERS:
Presidente - 1031499 - LAERCIO ALMEIDA DE MELO
Externo ao Programa - 1645492 - ALEX JOSE SOUZA DOS SANTOS - UFRNExterna à Instituição - LUANA MARIA MARTINS DE AQUINO - UNINASSAU