EST/CCET

DEPARTAMENTO DE ESTATISTICA

CENTRO DE CIÊNCIAS EXATAS E DA TERRA

Notícias

Ciclo de seminários do Departamento de Estatística da UFRN - 2019
06/08/2019 13:23

Ciclo de seminários do Departamento de Estatística da UFRN - 2019

Título: A survival model with Birnbaum-Saunders frailty for

uncensored and censored cancer data

Palestrante: Prof. Dr. Jeremias Leão – UFAM

Quando: 08 de agosto de 2019, quinta-feira, às 14:00h.

Onde: Sala 77 (Seminários) DEST/UFRN

Abstract: Survival models with frailty are used when additional data are non-available to explain the occurrence time of an event of interest. This non-availability may be considered as a random effect related to unobserved explanatory variables, or that cannot be measured, often attributed to environmental or genetic factors. We propose a survival model with frailty based on the Birnbaum-Saunders distribution. This distribution has been widely applied to lifetime data. The random effect is the “frailty”, which is assumed to follow the Birnbaum-Saunders distribution and introduced on the baseline hazard rate to control the unobservable heterogeneity of the patients. We use the maximum likelihood method to estimate the model parameters and evaluate its performance under different censoring proportion by a Monte Carlo simulation study. Two types of residuals are considered to assess the adequacy of the proposed model. Examples with uncensored and censored real-world data sets illustrate the potential applications of the proposed model.