Banca de DEFESA: LUCIMAR FERNANDES DE LIMA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : LUCIMAR FERNANDES DE LIMA
DATA : 17/11/2017
HORA: 15:00
LOCAL: ECT sala 08
TÍTULO:

BIOPOLYMER GEL FOR PEDICULOSIS TREATMENT

PALAVRAS-CHAVES:

BIOPOLYMER GEL; PEDICULOSIS;

PÁGINAS: 100
GRANDE ÁREA: Engenharias
ÁREA: Engenharia de Produção
SUBÁREA: Engenharia do Produto
ESPECIALIDADE: Desenvolvimento de Produto
RESUMO:

Pediculosis is characterized by lice infestation (Pediculus humanus capitis) in man. Since 1963 the pediculosis has been growing significantly, mainly in the school environment and urban centers, from the agglomeration and have seen in ease with which it is transmitted. Current treatments have side effects, posing a risk to the host's health, as well as promoting resistance to products, thus raising costs with treatments. The authors set out to develop an alternative, non-toxic, biocompatible and biodegradable treatment that would de-emphasize the genetic mutation presented by lice to the current treatments, in addition to managing innovation. To manage the project, the following methods were adopted: a) for the purification of the biopolymer, for this we separated 20g of commercial Polymar® chitosan, which was then dispersed in 2% aqueous SYNTH® acetic acid solution for 24 hours. We precipitated the entire polymer with the aid of SYNTH® NaOH and the precipitate was washed with double distilled water. b) Three samples of the hydrogel were prepared. Sample A was prepared from Sigma-Aldrich® chitosan, dispersed in SYNTH® aqueous acetic acid solution; Sample B and C were produced with Polymar® commercial chitosan, previously purified, the dispersions were shaken for 24 hours at room temperature (25 ± 2 ° C), after the preparation of the hydrogel was added to the essence; SYNTH® glycerin and alquiparabene; C) physical-chemical characterization of the samples through the organoleptic, pH and rheological analyzes of the hydrogel; d) to validate methodologically the product was carried out the in vitro test, which involved, sample selection and collection of material, standardization of wicks, examination and classification of pediculosis and finally application of the product; e) in cost management, the costs of water, energy, raw material and manpower required to produce the hydrogel were calculated with the intention of generating data for the next stages; f) valuation of technology, from the data generated by cost management. Patent application no. BR 1020150251793 was made to guarantee the intellectual property right of the product, the biopolymer hydrogel for the treatment of pediculosis, with low side effects and good theoretical tolerability, able to eliminate and control the pediculosis of Safe, eliminating the main reinfestation agent; The physical-chemical analysis showed that the product is within the required commercial standards, also showing good performance in the removal of the parasite. A new alternative product was developed for the treatment of pediculosis, with a low cost of production and good performance during the first in vitro tests, but it is necessary to carry out in vivo studies for Anvisa registration and possible commercialization.

MEMBROS DA BANCA:
Presidente - 3328363 - FRANCISCO IROCHIMA PINHEIRO
Interno - 1544724 - GLAUCIO BEZERRA BRANDAO
Externo à Instituição - EDUARDO PEREIRA DE AZEVEDO - UnP