Banca de DEFESA: RAYANE GRAYCE DA SILVA VIEIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : RAYANE GRAYCE DA SILVA VIEIRA
DATE: 28/02/2023
TIME: 14:00
LOCAL: UFRN
TITLE:

ACUTE EFFECTS OF MECHANICAL INSUFFLATION-EXSUFFLATION ON PEAK COUGH FLOW AND CHEST WALL VOLUMES IN SUBJECTS WITH AMYOTROPHIC LATERAL SCLEROSIS

KEY WORDS:

Neuromuscular Diseases; Cough; Plethysmography; Respiratory Therapy

PAGES: 70
BIG AREA: Ciências da Saúde
AREA: Fisioterapia e Terapia Ocupacional
SUMMARY:

Introduction: Amyotrophic Lateral Sclerosis (ALS) is a multisystemic neurodegenerative disease with clinical, genetic and neuropathological heterogeneity, with cerebral impairment, characterized by reduced lung volumes and ineffective cough, its main cause of morbidity and mortality. Mechanical insufflation-exsufflation (I-EM) consists of increasing the expiratory air flow and, thus, promoting an increase in the peak cough flow (PCF) and the removal of secretions. Objective: To analyze and describe the acute effects of applying the I-EM technique on PCF and operating volumes of the chest wall (CW) in individuals with ALS versus healthy peers. Methodology: This is an analytical cross-sectional study, where subjects with ALS were allocated to the experimental group (EG) and healthy subjects matched for age, gender and body mass index were allocated to the control group (CG). After collecting sociodemographic and clinical data, the subjects were assessed for lung function (spirometry) and respiratory muscle strength (maximum respiratory pressures). Then, the PT and PCF volumes were evaluated before (Pre I-EM) during (I-EM) and after the application of the I-EM technique (Post I-EM), through Optoelectronic Plethysmography (OEP). Results: Nine individuals with ALS were evaluated, of which 6 had spinal onset ALS. An increase of 0.73±1.4 L/s was observed in the PCF of holders with Spinal-onset ALS, while holders with bulbar-onset ALS showed a reduction of 0.82±1.2 L/s immediately after the application of the I-EM technique. As for the analysis parameters of the controlled pattern, the rapid and shallow breathing index (RSBI) at the Pre I-EM moment was 71.46 (38.53-122.40) and changed to 55.41 (29.42- 159.43) at the time Post I-EM. Conclusion: The results demonstrated that the I-EM technique led to an acute increase in the PCF value in spinal-onset ALS, as well as improved the pattern followed by the population followed, by reducing the RSBI.

COMMITTEE MEMBERS:
Externa à Instituição - ANA ALINE MARCELINO DA SILVA - ESTACIO
Presidente - 1545315 - GUILHERME AUGUSTO DE FREITAS FREGONEZI
Externa ao Programa - 2211046 - LUCIEN PERONI GUALDI - null