RELATIONSHIP BETWEEN REPRODUCTIVE HISTORY, PHYSICAL PERFORMANCE AND CARDIOVASCULAR RISK IN MIDDLE-AGED AND OLDER WOMEN: A CROSS-SECTION STUDY
Aging, cardiovascular disease, reproductive history, physical functional performance.
Introduction: During population aging, there is an increase in the number of health problems associated with this event, which may be related to life-course events, such as reproductive history. Among them, there is an increase in the prevalence of cardiovascular diseases and a decrease in physical performance, which may be responsible for reducing the quality of life and increasing health costs. Objectives: To analyze the relationship between reproductive history, cardiovascular risk and physical performance in middle-aged and elderly women. Materials and Methods: This is an observational, analytical, cross-sectional study with an epidemiological nature. The population consisted of women aged between 40 and 80 years, living in the municipalities of Parnamirim and Santa Cruz, Rio Grande do Norte. The variables of reproductive history (age at menarche, age at first birth, parity and menopausal status) were collected through self-report.
Physical performance was measured by the Short Physical Performance Battery, chair stand test and unipodal balance test with eyes open. Cardiovascular risk was analyzed using the Framingham Cardiovascular Risk Score. In addition, sociodemographic, socioeconomic data, body mass index, biochemical parameters and information on the participants' physical activity were collected. Regarding the statistical analyzes, in the first article, multiple linear regression analysis was performed between the variables that presented p <0.20 in the bivariate analysis and the Framingham Cardiovascular Risk Score. For the second article, the Multiple Linear Regression analysis was performed to estimate the relationship between the physical performance variables and the Framingham Cardiovascular Risk Score, adjusted by the covariables age, years of study and physical activity. Results: Regarding the results of the first article, with each increase in the number of children, women increased the Framingham Cardiovascular Risk Score by 0.19 points (β = 0.199, p = 0.01). In addition, those who were postmenopausal had an increase of 1.6 (β = -1.601, p = 0.002) in the Framingham Cardiovascular Risk Score. In the second article, cardiovascular risk remained significant for all performance variables, in which women classified as high cardiovascular risk had worse SPPB scores (β = -0.325, 95% CI -0.643: - 0.007), in the sit test and getting up (β = 0.697, 95% CI 0.030: 1.364) and in open eyes balance (β = -2.986, 95% CI -5.525: -0.446), in relation to those classified as low cardiovascular risk. Conclusion: The present study observed that women with high parity and who were in the post-menopause had higher scores for cardiovascular risk. And those with high cardiovascular risk had worse physical function. Thus, the investigation of these factors may serve to implement new strategies for their prevention and reversion and, with that, it may reduce physical impairment and disability in middle-aged and elderly women.