Cortical activity and motor performance during learning a virtual game in patients with stroke
Cerebrovascular disorders, Virtual reality exposure therapy, Upper extremity, Electroencephalography, Rehabilitation
Post-stroke sequelae indicate the need for interventions that favor the functional recovery of these patients. Objective: This study aimed to assess cortical activity and motor performance during the learning of a virtual reality game in stroke patients. Method: 12 patients participated in the study, 6 with left brain injury (LP), mean age 54.1 years (± 9.4) and 6 with right injury (RD), mean age ± 50.6 years (± 5.8) and 12 healthy individuals who activated the left (LH) and right (RH) hemispheres. Participants underwent an electroencephalographic evaluation when performing training with 3 blocks of 5 attempts of the virtual darts game (XBOX Kinect). Game performance was recorded using absolute (AE), constant (CE) and variable (VE) error measures. Data were analyzed using ANOVA with Tukey's post hoc test. Results: LP group had lower alpha potency in AF3 (left prefrontal cortex) (p = 0.031) and RP group in T8 (right temporal cortex) (p = 0.038). As for beta wave, there was less power in FC5 (left prefrontal cortex) (p = 0.001), and more power in P7 (left sensory area) (p = 0.010) for LP group. Patients showed higher AE and CE values than healthy ones (p = 0.015). Conclusion: The behavior of cortical activation and motor performance suggest the benefits of playing with virtual reality in stimulating motor learning, especially in patients with right brain injury. Perhaps patients with left brain injury need more time of exposure to virtual reality therapy to intensify brain plasticity and motor learning.