Banca de QUALIFICAÇÃO: INGRYD CAMARA MORAIS

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
DISCENTE : INGRYD CAMARA MORAIS
DATA : 04/07/2016
HORA: 11:00
LOCAL: Sala de reuniões do Instituto de Medicina Tropical
TÍTULO:

Use of Deltamethrin collars by dogs reduces human and dogs exposure to sand flies

PALAVRAS-CHAVES:

Sand flies; saliva; exposition

PÁGINAS: 21
GRANDE ÁREA: Ciências Biológicas
ÁREA: Bioquímica
RESUMO:

Visceral leishmaniasis (VL) is a disease caused by the protozoan Leishmania infantum, which has Lutzomyia longipalpis as the main vector  and domestic dogs are the main reservoir in Latin America. In Brazil, the principal control measure for VL has been the euthanasia of Leishmania infected dogs, with occasion spray for vector control. However, there is a lag between the identification of canine VL and the placement of intervention measures. Some studies report anti-sand fly saliva antibodies as a means to assess exposure to sand flies. This study aimed to determine the impact of impregnated deltamethrin collars Leishmania transmission in Brazil. Anti-saliva antibodies were determined by ELISA. We found that dogs from the intervention area had lower titer of anti-saliva antibodies after 6 months of collar use. Recombinant proteins correlated with salivary gland homogenate and can be used as a surrogate of sand fly exposure.  Humans residing in the intervention area were also less exposed to the vector in relation to the control area and had lower titers of anti-Leishmania antibodies. In conclusion, impregnated collars reduced Leishmania transmission and improved the health of the dogs in endemic areas for VL.

MEMBROS DA BANCA:
Externo ao Programa - 1714243 - DANIELLA REGINA ARANTES MARTINS SALHA
Externo ao Programa - 1212336 - ELIANA LUCIA TOMAZ DO NASCIMENTO
Externo ao Programa - 1046922 - LEONARDO CAPISTRANO FERREIRA