Banca de DEFESA: RAQUEL DANTAS COSTA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : RAQUEL DANTAS COSTA
DATA : 28/02/2019
HORA: 14:30
LOCAL: A definir
TÍTULO:

 

Biodegradable non-woven fabrics development and evaluation of medicine incorporation to its structure

PALAVRAS-CHAVES:

Blends. Non woven. Medicine. Evaporation

PÁGINAS: 50
GRANDE ÁREA: Engenharias
ÁREA: Engenharia Química
SUBÁREA: Tecnologia Química
ESPECIALIDADE: Têxteis
RESUMO:

Non-woven fabrics were obtained using the phase inversion method using the solvent evaporation technique from Polyacid Lactic/Poly (Adipate Co-Terephthalate Butylene) blend (PLA/PBAT) and the incorporation of a compound composed of Calcipotriol Hydrate and Betamethasone Dipropionate. The incorporation method of the drug according to it dissolution time was evaluated and the nonwoven were characterized by SEM, XRD, FTIR, TG, water vapor transmission and wettability. In the superficial SEM, a predominantly dense structure was observed in all samples. When analyzing transversely, elongate inclusions, characteristic of the blends, were observed in the systems with pure polymer, and in the membranes with drug included, the image shows uniformly distributed pores. By DRX the characteristic peaks of PBAT and PLA in the pure membrane were visualized and after the incorporation of the drug there was an increase of the respective peaks, indicating the effectiveness of the incorporation. The FTIR analysis showed that the bands increased with the addition of the drug, demonstrating that the drug was incorporated into the PLA/PBAT matrix. Thermogravimetric analysis showed that the presence of the drug decreased the thermal stability of the nonwoven, suggesting chemical interaction between the polymer and the drug. Wettability tests showed the presence of the drug alters the hydrophobicity of the system. From vapor transmission, a satisfactory flow was obtained, in accordance with the suggested need. Thus, the obtained non-woven fabrics are indicated so that they can be possibly used in a controlled drug delivery system.

MEMBROS DA BANCA:
Interna - 2254759 - AMANDA MELISSA DAMIAO LEITE
Externa ao Programa - 1718775 - KALINE MELO DE SOUTO VIANA
Externo à Instituição - ANTONIO MARCOS URBANO DE ARAUJO - UFRN
Externo à Instituição - RENE ANISIO DA PAZ - UFCG
Externa à Instituição - VANESSA DA NOBREGA MEDEIROS - UFCG