Banca de DEFESA: ISABELLE LISIANY DE LIMA TAVARES

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : ISABELLE LISIANY DE LIMA TAVARES
DATE: 21/03/2025
TIME: 14:00
LOCAL: Google Meet: https://meet.google.com/jij- xmvc-ndi
TITLE:

Prevalence of Staphylococcus aureus and Methicillin-resistant Staphylococcus
aureus colonizing the mouth of bedridden and homebound elderly people, and associated factors

 

KEY WORDS:

Oral cavity. Elderly health. Colonization.

PAGES: 75
BIG AREA: Ciências Biológicas
AREA: Microbiologia
SUMMARY:

The elderly population is the fastest growing demographic in the world. As
a consequence, there is an increase in elderly people living at home or even bedridden, with varying
degrees of dependence. With aging, the immune system becomes less efficient, generating systemic
impairments in the elderly, who become more vulnerable to possible bacterial infections. Therefore, the
objective of this study was to evaluate the prevalence of Staphylococcus aureus and Methicillin-resistant
Staphylococcus aureus (MRSA) colonizing the mouth of bedridden and homebound elderly people, as well
as evaluating factors associated with this colonization. For this, 263 elderly people were visited at their
homes in the city of Natal/RN, samples of the oral environment were collected using swabs, which were
placed in saline solution and sent to the research laboratory. The samples were pipetted into BHI (Brain Heart Infusion Broth) enrichment broth and after incubation, they were seeded on the salt mannitol agar
selective culture medium. Colonies suggestive of Staphylococcus aureus were reisolated with subsequent
identification through conventional laboratory tests and mass spectrometry (MALDI-TOF). The susceptibility
profile and identification of the MRSA lineage were performed using the disk diffusion method. Data
related to sociodemographic factors and self-perception of health were collected through the application of
a questionnaire. The prevalence of elderly people colonized by S. aureus was 13.3% (n=35) and for MRSA it
was 1.5% (n=4). MRSA was resistant only to penicillin, erythromycin and clindamycin. Statistical tests
showed a significant association between the presence of S. aureus and the variables male sex (p= 0.033),
bedridden elderly (p=0.020), poor self-perceived general health (p=0.001) and difficulty eating (p=0.004).
The presence of S. aureus and especially the MRSA lineage colonizing elderly people may represent a risk to
the health of this population, especially due to their greater immunological vulnerability.

 

 

COMMITTEE MEMBERS:
Interna - 1049952 - DEYSIANE OLIVEIRA BRANDAO
Externa à Instituição - GILMARA CELLI MAIA DE ALMEIDA - UERN
Interna - 1452833 - MARIA CELESTE NUNES DE MELO